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<title>Chinese Journal of Magnetic Resonance Imaging RSS feed</title>
<link>http://med-sci.cn/cgzcx/en/contents_list.asp?issue=201001</link>
<language>zh-cn</language>
<copyright>An RSS feed for Chinese Journal of Magnetic Resonance Imaging</copyright>
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<title><![CDATA[Functional MRI evaluation on linguistic center in patients with expressive aphasia after cerebral infarction]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.3969/j.issn.1674-8034.2010.01.004</link>
<description><![CDATA[Objective: To evaluate the brain activation in patients with expressive aphasia after cerebral infarction. Materials and Methods: Fifteen patients suffering from expressive aphasia after cerebral infarction and 15 normal middle-old aged subjects were recruited in this study. All patients and subjects received block-designed category-member generation task fMRI. SPM2 software was used to process fMRI data. Intra- and inter-group analysis was performed to obtain activated mapping in of two groups and different mapping between two groups. MNI coordinate and activated intensity of the brain regions were recorded. Results: Ten male patients and ten male controls were selected after head motion and machine noise had been ruled out. Activated regions of the control group included Broca’s area, right Broca’s homologue area, supplement motor area (SMA), left anterior insula, left superior temporal gyrus and left precentral gyrus. Activated regions of the patient group included left middle frontal gyrus, postcentral gyrus, inferior parietal lobule, precuneus lobe, right inferior frontal gyrus, bilaterial precentral gyrus, insula, thalamas,striatum, SMA and cerebellum. When contrast to the patients group, only the posterior part of left inferior frontal gyrus showed activation in control group. There was no signiﬁ cant activation when patients group contrast to control group. Conclusion: Compared with normal middle-old aged controls, the activation level of the posterior part of left inferior frontal gyrus (Broca's area) declined or disappeared in patients with expressive aphasia after cerebral infarction, which suggest that the damage to the Broca’s area has led to the occurrence of expressive aphasia.]]></description>
<pubDate>Wed,20 Jan 2010 00:00:00  GMT</pubDate>
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<title><![CDATA[Investigation of brain motor functional connectivity in ischemic stroke patients after rehabilitative treatment with resting-state functional MRI]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.3969/j.issn.1674-8034.2010.01.005</link>
<description><![CDATA[Objective: To investigate the change of brain motor functional connectivity in ischemic stroke patients after rehabilitative treatment with resting-state functional MRI(fMRI). Materials and Methods: Resting-state fMRI was employed on two sub-acute ischemic stroke patients before and after the rehabilitative treatment with functional electric stimulation (FES), and the difference of brain motor functional connectivity was analyzed. Results: After rehabilitative treatment, motor function of upper extremity was ameliorated, and functional connectivity of bilateral motor cortex was decreased. There was the correlation between behavioral improvement and connectivity decrease.  Conclusion: The dependence of affected cerebral hemisphere on unaffected cerebral hemisphere was decreased after motor functional improvement of upper extremity.]]></description>
<pubDate>Wed,20 Jan 2010 00:00:00  GMT</pubDate>
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<title><![CDATA[Correlation of corticospinal tract injury and the outcome of motor function after six months of intracerebral hemorrhage: quantitative evaluation with diffusion tensor tractography]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.3969/j.issn.1674-8034.2010.01.006</link>
<description><![CDATA[Objective: To investigate the predicting value by analyzing corticospinal tract (CST) injury to the motor function after intracerebral hemorrhage (ICH) with quantitative diffusion tensor tractography (DTT). Materials and Methods: Diffusion tensor imaging was performed in twenty-ﬁ ve acute ICH patients, whose hemorrhage involves basal ganglia, internal capsule or corona radiate. The affected side of CST was reconstructed with Volume-One 1.64 and diffusion Tensor Visualizer II(dTV II) software from Tokyo University. The relative remaining number of CST, which is as quantitative indicator, was calculated. Fugl-Meyer scoring was used to evaluate the prognosis. Results: The correlation coefﬁ cient (r value) between relative remaining number of CST and Fugl-Meyer score after six month of ICH is 0.879 (P<0.01). Conclusion: Quantitative DTT of CST could be used to predict the motor function in ICH patients.]]></description>
<pubDate>Wed,20 Jan 2010 00:00:00  GMT</pubDate>
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<title><![CDATA[Diffusion weighted MR imaging in differentiation of low grade gliomas]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.3969/j.issn.1674-8034.2010.01.007</link>
<description><![CDATA[Objective: To assess the value of diffusion weighted imaging (DWI) in the differentiation of intracranial low grade gliomas. Materials and Methods: Twenty-one patients with pathologically proved low grade gliomas were divided into three groups: 9 astrocytomas (AC, grade II), 5 oligodendrogliomas (OD, grade II) and 7 oligodendroastrocytomas (OA, grade II). The apparent diffusion coefﬁ cient (ADC) and exponent diffusion coefﬁ cient (EDC) values in tumor solid part, peritumor edema and contralateral white matter of each tumor were measured, relative ADC (rADC) and relative EDC (rEDC) was calculated. Mean values of ADC, rADC, EDC and rEDC were analyzed among the three groups. Results: Mean ADC and rADC of tumor solid part were 1.12 and 1.52 for OD, 1.14 and 1.48 for OA, 1.93 and 2.38 for AC respectively. Mean EDC and rEDC of tumor solid part was 0.33 and 0.70 for OD, 0.32 and 0.71 for OA, 0.15 and 0.34 for AC, respectively. There was signiﬁ cant difference (P<0.01) between OD and AC, OA and AC in all parameters of tumor solid part. However, no signiﬁ cant difference was found between OD and OA in all parameters of tumor solid part. In peritumor edema, the difference was not signiﬁ cant among the three groups in all parameters. Conclusion: DWI may be helpful in differentiating OD and OA from AC, but not between OD and OA.]]></description>
<pubDate>Wed,20 Jan 2010 00:00:00  GMT</pubDate>
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<title><![CDATA[Susceptibility weighted imaging of reperfusion injury after mass cerebral infarction and correlation to clinical measures]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.3969/j.issn.1674-8034.2010.01.008</link>
<description><![CDATA[Objective: To evaluate susceptibility-weighted imaging (SWI) in the assessment of reperfusion injury after mass cerebral infarction and the correlation between imaging manifestations and clinical measures. Materials and Methods: Twenty-one patients with mass cerebral infarction were determined by the clinical and imaging manifestations. Patients with post-infarction hemorrhage were divided into mild, moderate and severe groups according to the volume of bleeding. The extent of micro-vessels around the infarction focus revealed in SWI was classified as 0-II degrees. The NIHSS scores of all the subjects were obtained and were correlated to SWI results. Results: Spontaneous post-infarction hemorrhage was observed in 16 subjects (76.2%), with 4 cases (25.0%) of severe bleeding, 5 cases (31.3%) of moderate bleeding, and 7 cases (43.8%) of mild bleeding, among which bleeding was found in 11 cases (68.8%) of sub-acute period. Severe hemorrhage positively correlated with NIHSS scores (rs=0.765, P=0.001). Micro-vessels around the lesions were found in 14 cases (66.7%). In 21 cases, 10 cases (47.6%) were II degree, 4 cases (19.0%) were I degree, 7 cases (33.3%) were 0 degree. The display degree of micro-vessels had no signiﬁ cant correlation with the NIHSS score (rs=0.408, P=0.066). Conclusion: SWI can make a sensitive, objective assessment of the reperfusion injury and collateral circulation after cerebral infarction, which is promisingly to be an effective evaluation method for the prognosis and treatment of the patients with infarction.]]></description>
<pubDate>Wed,20 Jan 2010 00:00:00  GMT</pubDate>
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<title><![CDATA[Initial study of susceptibility weighted imaging in brain masses]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.3969/j.issn.1674-8034.2010.01.009</link>
<description><![CDATA[Objective: To evaluate the value of susceptibility weighted imaging (SWI) in the diagnosis of brain masses. Materials and Methods: Forty-one patients with brain neoplasms underwent conventional MR T1WI, T2WI and SWI scanning. Thirty of them received both contrast enhanced T1WI and SWI (CE-T1WI and CE-SWI). Tumor visibility, edema, blood products, calcium, and vessels were observed respectively on SWI, the images of all sequences were scored from 0 to 3, according to their ability of depicting the observation projects above. Statistical analysis was conducted to compare the scores among these sequences. Results: Meningiomas and low-grade astrocytomas showed equisignal or mild hypersignal intensity; all recurrent meningiomas, high-grade astrocytomas and metastases in major displayed as mild low signal intensity. Venous vasculature both inside meningiomas and low-grade astrocytomas were relatively poorer than the recurrent ones, high-grade astrocytomas and metastases; peri-venous showed arc compressed by the tumor in meningiomas, while displayed variously in other tumors. Calcium within the tumor appeared mainly in hypointense signal intensity surrounded by hyperintense signal ring on phase image, while blood product appeared conversely. Peri-edema displayed as high signal intensity. There was statistical difference of scores between SWI and conventional T1WI, T2WI in displaying blood products, calcium, and venous vasculature (P<0.01). There was no signiﬁ cant difference of scores between SWI and T2WI in displaying edema. Signiﬁ cant difference between the scores in detection of tumor visibility was found on the contrast enhanced sequences and non-contrast enhanced sequences (P<0.01). Conclusion: SWI sequence not only shows the general imaging features of brain masses but also detects venous vasculature, blood product and calcium within the tumor with superlative contrast. Different from conventional sequences, SWI shows unique details about internal architecture which is determined primarily by blood products. Phase image of SWI is helpful in differentiating blood product and calcium within the tumor.]]></description>
<pubDate>Wed,20 Jan 2010 00:00:00  GMT</pubDate>
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<title><![CDATA[Correlation between angiogenesis and multi-parameters of dynamic contrast enhancement MRI for assessments of benign and malignant breast lesions]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.3969/j.issn.1674-8034.2010.01.010</link>
<description><![CDATA[Objective: To explore the correlation between microvessel density (MVD), vascular endothelial growth factor (VEGF) and multi-parameters of dynamic contrast-enhanced (DCE) MRI, and the parameters’ value for assessments of benign/malignant breast lesions. The multi-parameters includes: the type of time-signal intensity curve (TIC), early-phase enhancement rate (EER), maximum linear slope rate (Slope), maximum enhancement rate (SImax), peak time (Tpeak), the number of tumor vessels on maximum intensity projection map (NTV). Materials and Methods: Fifty-two patients with breast lesions received preoperative DCE-MRI scans. All DCE parameters were recorded for correlation analysis. All patients were operated within 1 week after DCE-MRI. Histopathological and immunohistochemical exams were performed on the excisions to determine malignancy and the expression of marginal MVD, central MVD and VEGF. Correlations between DCE-MRI parameters and MVD, VEGF were analyzed. Results: The marginal MVD and VEGF demonstrated linear correlation with TIC, Tpeak and NTV. Strongest correlation was found between TIC and marginal MVD, as well as between Tpeak and VEGF. Central MVD has no signiﬁ cant correlation with all DCE parameters. Among the 52 patients, there were 22 malignant and 30 benign lesions. In comparison with benign lesions, the malignant lesions showed a washout TIC type III, higher EER, more NTV, and high expression of MVD and VEGF, but lower SImax  and Tpeak (P<0.005). Slope has no significant difference between malignant and benign groups. Conclusion: Among the DCE-MRI parameters, TIC, Tpeak, and NTV demonstrated correlation with MVD and VEGF, those parameters may reflecting the different angiogenesis between malignant and benign breast lesions, and therefore are most meaningful for the diagnosis of breast lesions.]]></description>
<pubDate>Wed,20 Jan 2010 00:00:00  GMT</pubDate>
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<title><![CDATA[Diffusion tensor imaging in evaluation of benign prostatic hyperplasia: preliminary study]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.3969/j.issn.1674-8034.2010.01.011</link>
<description><![CDATA[Objective: To investigate the value of diffusion tensor imaging (DTI) in evaluating the structure of normal peripheral zone (PZ) and benign prostate hyperplasia (BPH). Materials and Methods: Twenty five patients with BPH were included in this study. DTI was performed using a 1.5 Tesla superconducting magnetic scanner (SIEMENS) equipped with a pelvic phased-array multi-coil. All data were transferred to SIEMENS Leonardo Workstation and different regions of interest (ROI) of PZ and BPH were drawn by a radiologist. Using the DTI card, the fractional anisotropy (FA) and mean apparent diffusion coefﬁ cients (ADC) of DTI were calculated and the corresponding index maps were produced. Results: The FA of PZ and BPH were 0.16±0.03 and 0.23±0.04, respectively. The FA of PZ were lower than that of BPH (P<0.05). The mean ADC value of BPH (1.37±0.27×10-3 mm2/s) was lower than that of PZ (1.85±0.34×10-3 mm2/s) (P<0.05). The directions, length and amount of BPH were different from those of PZ. Conclusion: DTI can be used to evaluate the three-dimensional architecture of PZ and BPH, which has the potential to provide useful information for the treatment of BPH.]]></description>
<pubDate>Wed,20 Jan 2010 00:00:00  GMT</pubDate>
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<title><![CDATA[Correlation between the severity of acute pancreatitis on MR imaging and liver function]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.3969/j.issn.1674-8034.2010.01.012</link>
<description><![CDATA[Objective: To investigate the correlation between the severity of acute pancreatitis (AP) on MR imaging and liver function. Materials and Methods: There were 64 patients with AP, all of whom had performed abdominal MR imaging. AP was categorized into types of edematous and necrotizing, and graded into mild (0-3 scores), moderate (4-6 scores) and severe (7-10 scores) according to the MR severity index (MRSI). The results of liver function test (ALT and AST) was noted and compared with the severity of AP on MRSI. Results: In the 64 patients with AP, 56 patients were edematous and 8 patients were necrotizing on MR imaging. The frequencies of ALT and AST elevated were both 100% in necrotizing AP, which were signiﬁ cantly larger than 55.4% (ALT) and 60.7% (AST) in edematous AP (P=0.014 and P=0.027, respectively). The frequencies of ALT and AST elevated were 48.8% and 53.5% in mild AP, 73.7% and 78.9% in moderate AP, and both 100% in severe AP, respectively. The frequency increasing of liver function abnormality tended to follow MRSI scores increasing. However, no signiﬁ cant difference for the frequencies can be seen among mild, moderate and severe AP. Conclusion: The necroses of AP on MR imaging may help to predict liver function abnormality in AP. However, MRSI could not be as index for predicting the abnormality of liver function in AP.]]></description>
<pubDate>Wed,20 Jan 2010 00:00:00  GMT</pubDate>
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<title><![CDATA[In vivo MR tracking imaging of SPIO-labeled adipose-derived stem cells transplantation in rat models of brain infarction]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.3969/j.issn.1674-8034.2010.01.013</link>
<description><![CDATA[Objective: To label adipose-derived stem cells (ADSCs) by complex of superparamagnetic iron oxide (SPIO) with poly-L-Lysine (PLL) and to investigate the distribution and migration of ADSCs in rat model of ischemia brain injury. Materials and Methods: The ligation of middle cerebral artery under microscope was used to cause focal brain infarction in rats. ADSCs labeled with SPIO were grafted stereotactically into the contralateral cerebral hemisphere. All animals were randomly divided into control group (n=12), SPIO-labeled ADSCs group (n=12) and SPIO-unlabeled ADSCs group (n=12). The neurological severity score (NSS) was used to evaluate neurological function recovery of rats at definite time following the transplantation. The transplanted ADSCs were analyzed in recipient rat brains by pathological method. The biodistribution of grafted ADSCs was monitored noninvasively by MR imaging. Results: Significant improvement in NSS was observed in rats receiving ADSCs transplantation compared with control group after 3 weeks (P<0.05). The transplanted ADSCs preferentially engrafted migrated toward the injured brain through callosum. MR imaging showed remarkable hypointense signal in the region of transplantation site, callosum and the rim of infarction especially in T2WI, T2 gradient-recalled echo sequence. Conclusion: Neurological and functional improvement was observed in rats with ADSCs transplantation following ischemia brain injury. In vivo MR tracking of SPIO-PPL complex labeled ADSCs could evaluate the therapeutic effect and visualize the distribution and migration of SPIO-labeled ADSCs following transplantation.]]></description>
<pubDate>Wed,20 Jan 2010 00:00:00  GMT</pubDate>
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<title><![CDATA[Diffusion weighted imaging features after hepatic right portal vein ligation in rats]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.3969/j.issn.1674-8034.2010.01.014</link>
<description><![CDATA[Objective: To study the diffusion weighted imaging (DWI) characters of hepatic cell focal apoptosis. Materials and Methods: Thirty SD rats about 300g are operated by hepatic right portal vein ligation and divided into 5 groups. T1WI, T2WI, DWI and apparent diffusion coefficient (ADC) image were obtained at 3 hours, 1 day, 3 days, 7 days, 14 days after the operation. After MRI examination, rats were sacrificed and the right hepatic lobes were sampled for pathology, electronic microscopy and TUNEL staining examination. Results: All right hepatic lobe focal apoptosis in 30 rats was certiﬁ cated by pathology, electronic microscopy and TUNEL staining examination. Occurring from 3 hours after operation, apoptosis cell gradually increased with time. It was high signal at T1-weighted image in each group after operation, low signal at T2-weighted image after 3 hours and high signal in other groups, and slightly high signal at diffusion weighted image after 3 hours, and high signal in other periods. The ADC value of the right lobe was less than the left lobe in each group (P<0.05),  the relative ADC value increased in all groups with time. The ADC value, signal-noise ratio (SNR) and sensitivity of DWI decreased with b value increasing, but the speciﬁ city increased. Conclusion: There are focal apoptosis in right hepatic lobes of rats after the portal vein ligation. What’s more, its signal in DWI image and the ADC value is unique, so DWI is useful to judge the success of hepatic vessel ligation and detect focal apoptosis area in vivo.]]></description>
<pubDate>Wed,20 Jan 2010 00:00:00  GMT</pubDate>
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<title><![CDATA[Neonatal hypoxic-ischemic encephalopathy: detection with diffusion-weighted and diffusion-tensor MR imaging]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.3969/j.issn.1674-8034.2010.01.015</link>
<description><![CDATA[Hypoxic-ischemic encephalopathy (HIE) is the primary cause of neurological disorders during perinatal period. The pathophysiologic mechanism and patterns of injury in HIE are intricacy. There are different patterns in magnetic resonance imaging (MRI) as the results of the differences in brain maturity, severity and duration of insult. In this article, we review the principle of diffusion-weighted imaging (DWI) and diffusion-tensor imaging (DTI), and their advantage for detection of HIE. The changes of DWI and DTI parameters in neonatal HIE were retrospectively analyzed and summarized according to the previous literatures. It indicates that DWI and DTI are earlier and more sensitive than the conventional MRI in detecting the lesion of neonatal HIE. Moreover, the DWI parameter is associated with the variation in cellular and molecular level. The injury in neural microstructures, such as the axon and myelin, can be illustrated by DTI fiber tracking and performed quantitative analysis by different DTI parameters. Therefore, it is no doubt that these new approaches in MRI techniques can help diagnosis, affect prognosis, and facilitate earlier treatment to the neonatal HIE in clinic.]]></description>
<pubDate>Wed,20 Jan 2010 00:00:00  GMT</pubDate>
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<title><![CDATA[TrueForm technique in high field magnatic resonance imaging]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.3969/j.issn.1674-8034.2010.01.016</link>
<description><![CDATA[As one of the cutting-edge technologies in high field MRI, TrueForm, based on Siemens’ unique Tim technology, overcomes the limitations in current high field MRI systems and represents the trends of medical MRI products. TrueForm technology not only optimizes the hardware, including RF, gradient and magnet, of MRI systems, but also comprehensively improves the software, such as data acquisition, processing, etc. This article will elaborate the features of TrueForm in three aspects, including RF system, gradient system and magnet.]]></description>
<pubDate>Wed,20 Jan 2010 00:00:00  GMT</pubDate>
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<title><![CDATA[MR guidance techniques in the diagnosis and therapy of brain neoplasms]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.3969/j.issn.1674-8034.2010.01.018</link>
<description><![CDATA[The advantages of MR guidance in intraoperative brain neoplasms resection as follows: (1) Intraoperative MR imaging provides an accurate depiction of the entire surgical volume during the procedure, and allows updating of the changing anatomic relationships as the procedure processes. This real-time guidance can limit the damage of functionally intact and normal brain tissue. (2) The margins of brain neoplasms usually can be delineated more accurately with MR imaging than with direct visual inspection. Intraoperative MR imaging could increase the rate of gross total removal for brain neoplasms. (3) The complications such as haematoma could be detected by intraoperative MRI at the end of the procedures, which can be immediately resolved before suturing the incision. (4) Functional MR imaging and dynamic enhancement MR imaging can further helped to improve the safety and efficacy. In the article, MR guidance techniques in the diagnosis and treament of brain neoplasms will be reviewed.]]></description>
<pubDate>Wed,20 Jan 2010 00:00:00  GMT</pubDate>
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