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<title>Chinese Journal of Magnetic Resonance Imaging RSS feed</title>
<link>http://med-sci.cn/cgzcx/en/contents_list.asp?issue=201401</link>
<language>zh-cn</language>
<copyright>An RSS feed for Chinese Journal of Magnetic Resonance Imaging</copyright>
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<title><![CDATA[Differentiation between recurrent gliomas and radiation-induced brain injuries using DCE-MRI]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.3969/j.issn.1674-8034.2014.01.001</link>
<description><![CDATA[Objective: To analysis whether hemodynamic parameters derived from dynamic contrast-enhanced (DCE) T1-weighted magnetic resonance imaging (MRI) can be used to distinguish recurrent gliomas from radiation-induced brain injury. Materials and Methods: Twenty eight patients who were being treated for glial neoplasms underwent conventional and DCE-MRI using a Philips 3.0 T scanner. Penetration analysis software can be applied to obtain T1-weighted signal intensity-time curves. The pharmacokinetic modelling was based on a two-compartment model that allows for the calculation of Ktrans (transfer constant between intravascular and extravascular, extracellular space), Ve (extravascular, extracellular space), kep (transfer constant from the extracellular, extravascular space into the plasma), Regions of interest (ROIs) were drawn manually around the entire recurrence-suspected contrast enhanced region which was measured three times and then obtain average value. A definitive diagnosis was established at subseuent surgical resection (seventeen) or clinicoradiologic follow-up (eleven). nonparametric test was uesd to determine whether there was a difference between glioma recurrence and radiation-induced brain injury.  Results: The Ktrans, Ve, Kep values in the normal white matter were significantly different than those in the radiation necrosis and recurrent gliomas (P<0.01). The significantly different hemodynamic parameters between the recurrent tumor lesions and theradiation-induced necrotic sites were Ktrans and Ve, which were significantly higher in the recurrent glioma group than in the radiation necrosis group (P<0.01). A Ktrans cutoff value higher than 0.12 showed 100% sensitivity and 87% specificity for detecting the recurrent gliomas, The area under the ROC curve of Ktrans is 0.974 (P<0.01) and Ve is 0.872 (P=0.01). The kep values in recurrent tumors were not significantly higher than those in radiation-induced necrotic lesions (P>0.05).  Conclusions: DCE-MRI can be used to identify glioma recurrence with radiation-induced brain injury, Ktrans  value and Ve value have important clinical significance.]]></description>
<pubDate>Mon,20 Jan 2014 00:00:00  GMT</pubDate>
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<title><![CDATA[Differentiation between recurrent glioma and radiation-induced brain injuries using perfusion weighted imaging and diffusion weighted imaging]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.3969/j.issn.1674-8034.2014.01.002</link>
<description><![CDATA[Objective: To evaluate the perfusion weighted imaging (PWI) and diffusion weighted imaging (DWI) in the differentiation of recurrent glioma and radiation-induced brain injuries. Materials and Methods: 30 patients with glioma having radiotherapy after surgery, presenting newly developed abnormal enhancement, were included in the study. The MR examintions comprised of conventional MR imaging, DWI and PWI. Comparison of abnormal enhancement parameter ratio area and contralateral normal area, including the relative cerebral blood volume (rCBV), relative cerebral blood flow (rCBF), relative mean transit time (rMTT) and the ratio of ADC. Results: Twenty of the 30 patients were proved glioma recurrence, ten were proved radiation-induced brain injuries. The mean rCBV ratio 2.11 (range 1.03—4.72) in glioma recurrence was higher than that 0.53 (range 0.24—1.10) in radiation injuries (P<0.05). The mean rCBF ratio 1.895 (range 0.8—4.56) in glioma recurrence was higher than that 0.515 (range 0.2—1.02) in radiation injuries (P<0.05). Resutls obtained in DWI were not statistically significant different between two analysed groups. The ADC ratio of glioma recurrence is slightly lower than the ADC ratio of radiation-induced brain injuries. Conclusions: PWI seems to be most reliable in differentiation between glioma recurrence and radiation-induced brain injuries. DWI do not differentiate analyzed groups with statistical significance, despite tendency to lower ADC values in recurrence group than in radiation-induced brian injuries.]]></description>
<pubDate>Mon,20 Jan 2014 00:00:00  GMT</pubDate>
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<title><![CDATA[Application value of MR spectroscopy in the peritumoral tissue of brain astrocytic tumours]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.3969/j.issn.1674-8034.2014.01.003</link>
<description><![CDATA[Objective: To discuss metabolic feature in the peritumoral tissue of different ranks brain astrocytic tumours with multi-voxel proton magnetic resonance spectroscopy (1H-MRS), and estimate its application value on of brain astrocytic tumours. Materials and Methods: 82 patients with brain astrocytic tumours confirmed by postoperative pathologic were collected, which were divided into low grade astrocytic tumours (WHO I—II) 32 cases, and high  grade astrocytic tumours (WHO III—IV) 50 cases. The semiquantitative and relatively quantitative ratio of metabolic of the parenchyma area,peritumoral tissues area,and area with normal area were measured, and value was set as P<0.05. Results: The relative quantitative ratios of Cho/Cr, Cho/NAA significantly differed in peritumoral tissues area of the high grade astrocytic tumours and the low grade astrocytic tumours (P<0.01), but NAA/Cr had no significant difference (P>0.05). Conclusions: The changes of the MRS quantitative ratio in brain astrocytic tumours peritumoral tissues area reflects the level of different tumor biological behavior, and it has important clinical value in determining the classification of the brain astrocytic tumours and the scope of attack.]]></description>
<pubDate>Mon,20 Jan 2014 00:00:00  GMT</pubDate>
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<title><![CDATA[Diagnosis and differential diagnosis of MRI in hypertensive encephalopathy]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.3969/j.issn.1674-8034.2014.01.004</link>
<description><![CDATA[Objective: To diagnosis and differential diagnosis in the patients with hypertensive encephalopathy.  Materials and Methods: The clinical data including MRI of 38 patients with hypertensive encephalopathy were analyzed retrospectively.  Results: There were positive findings in 38 patients on MRI. The positive findings mainly included brain edema and focal cerebral hemorrhage. The systolic blood pressure ranged from 180 to 230 mm Hg and diastolic blood pressure from 120 to 150 mm Hg in the patients. There were the clinical manifestations of high intracranial pressure in all the patients. Conclusions:  The main manifestation of imaging is cerebral edema, and the diagnosis and differential diagnosis may be made by imagings combined with clinical manifestations in the patients with hypertensive encephalopathy.]]></description>
<pubDate>Mon,20 Jan 2014 00:00:00  GMT</pubDate>
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<title><![CDATA[1H magentic resonance spectroscopy in the diagnoisis of multiple sclerosis]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.3969/j.issn.1674-8034.2014.01.005</link>
<description><![CDATA[Objective: To assess the utility of 1H magentic resonance spectroscopy (1H-MRS) in diagnosing and characterizing multiple sclerosis (MS). Materials and Methods: 1H-MRS was carried out in 29 patients with MS and 29 age-matched healhy control subjects. The areas under the peaks of the metabolites of N-acetylaspartic acid (NAA), creatine (Cr), choline compounds (Cho) and lactic acid (Lac) were calculated. The metabolics of NAA/(Cr+Cho), Cho/Cr and Lac/Cr were compared between the two groups. Results: The value of NAA/(Cr+Cho), Cho/Cr and LAC/Cr of MS group and control group were 0.56, 1.49, 3.35 and 0.78, 1.19, 0.23, respectively. Compared with the control group, NAA/(Cr+Cho) reduced, Cho/Cr and Lac/Cr increased in the MS group, all of which had staistically singnificance (P<0.05). Conclusions: 1H-MRS has high specificity, can provide reliable diagnostic information for early diagnosis of MS, and may have important significance to guide clinical treatment and judging prognosis.]]></description>
<pubDate>Mon,20 Jan 2014 00:00:00  GMT</pubDate>
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<title><![CDATA[White matter variations in preterm and full term neonates with punctate white matter lesions: a diffusion tensor study based on tract-based spatial statistics]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.3969/j.issn.1674-8034.2014.01.006</link>
<description><![CDATA[Objective: The aim of this diffusion tensor imaging (DTI) study was to explore the white matter (WM) variations due to punctate white matter lesions (PWML) in preterm and full term neonates using tract-based spatial statistics (TBSS) analysis. Materials and Methods: 21 preterm and 25 full term patients with matched control neonates who underwent conventional MRI and DTI were enrolled. The differences of fractional anisotropy (FA), axial diffusivity (AD), radial diffusivity (RD) and mean diffusivity (MD) values between PWML group and paired control group were analyzed by using TBSS in preterm and full term neonates separately. Results: In both full term and preterm neonates with PWML, FA decreased significantly in optic radiation (OR), posterior limb of internal capsule (PLIC), splenium of the corpus callosum (SCC) and body of the corpus callosum (BCC). Unlike single FA decrease in preterm neonates, RD and MD increased while FA decreased in full term neonates. Additional impaired WMs could be observed in full term neonates in genu of corpus callosum (GCC), corona radiate (CR), anterior and posterior central gyrus (ACS & PCS). Conclusions: The white matter (WM) variations due to neonatal PWML were not limited in the regions where these lesions located, and they were different between preterm and full term neonates in the distribution and extent.]]></description>
<pubDate>Mon,20 Jan 2014 00:00:00  GMT</pubDate>
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<title><![CDATA[The value of quantitative dynamic-enhanced MRI in evaluating extra-ocular muscle involvement in patients with chronic thyroid-associated ophthalmopathy]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.3969/j.issn.1674-8034.2014.01.007</link>
<description><![CDATA[Objective: To evaluate retrospectively dynamic-enhanced MRI (DCE-MRI) features of involved extra-ocular muscle in patiens with chronic thyroid-associated ophthalmopathy (TAO). Materials and Methods: MRI examination were performed on 17 patients with chronic TAO and 27 healthy controls. Parameters of extra-ocular muscles of patients and controls, including Ktrans, Kep, Ve, IAUC, were produced by post process software. ROIs were drawn slice by slice along the edge of muscle belly, and repeated one month later. Results: There were no statistical difference between left and right muscles both in patients and controls (P>0.05). The mean values of Ktrans, Kep, IAUC of medial rectus and mean values of Ktrans, Kep, Ve value of inferior rectus in patiets were lower than those of healthy controls (P<0.05). The mean values of Kep, Ve, IAUC of superior rectus muscle complex in patients were higher than those of controls (P<0.05). There were no statistic differences in mean value of Ktrans, Kep, Ve, IAUC of lateral rectus and the mean value of Ve of medial rectus, the mean value of IAUC of inferior rectus and the mean value of Ktrans of superior rectus muscle complex between patients and controls (P>0.05). Among the all quantitative parameters, the mean value of Ktrans was most sensitive (The area under ROC curve of Ktrans was 0.753 in medial rectus and 0.650 in inferior rectus). Conclusions: DCE-MRI could be applied to evaluate extra-ocular muscles involvement in patients with chronic TAO. The medial rectus muscle and the inferior rectus muscle were most commonly involved in patients with TAO. The mean value of Ktrans value could be used to reflect the microcirculatory perfusion.]]></description>
<pubDate>Mon,20 Jan 2014 00:00:00  GMT</pubDate>
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<title><![CDATA[Early evaluation of 131I nuclide therapeutic effect in Graves’disease patients by MRI]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.3969/j.issn.1674-8034.2014.01.008</link>
<description><![CDATA[Objective: To evaluate the early effect of 131I nuclide therapy in Graves’ disease by MRI. Materials and Methods: MRI was performed in 18 GD patients before and at 1, 3 months after 131I nuclide therapy respectively. According to the follow-up thyroid function laboratory results at 3 months, the enrolled GD patients were divided into effective group (n=9) and ineffective group (n=9). Overall thyroid volume and apparent diffusion coefficient (ADC) values were measured blindly and the changes of volumes and ADCs were compared longitudinally in both groups. Results: Compared with GD patients before 131I nuclide therapy, the thyroid volume decreased significantly in effective group (P<0.01) in the patients one month after therapy, while there was no change in ineffective group (P=0.07), and there was no change for the average thyroid ADC values in both groups (P=0.54, 0.27). The thyroid volume decreased significantly in both effective group (P<0.01) and ineffective group (P<0.05) in GD patients three months after therapy compared with patients before therapy; the average thyroid ADC values decreased in effective group (P<0.05), however, there was no change in ineffective group (P=0.46). The thyroid volume decreased significantly in effective group (P<0.05) but there was no change in ineffective group (P=0.20) three months after therapy compared with that of one month after therapy, and there was no change for the average thyroid ADC values in both groups (P=0.53, 0.08) between three and one months after therapy.  Conclusion: The overall thyroid volume and the average ADC values could demonstrate early response after 131I nuclide therapy in Graves’ disease patients.]]></description>
<pubDate>Mon,20 Jan 2014 00:00:00  GMT</pubDate>
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<title><![CDATA[Preliminary study on pathomechanism of non-small-cell lung carcinoma using apparent diffusion coefficient]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.3969/j.issn.1674-8034.2014.01.009</link>
<description><![CDATA[Objective: To investigate the value of apparent diffusion coefficient (ADC) in predicting the pathomechanism of non-small-cell lung carcinoma (NSCLC). Materials and Methods: Four-six patients with NSCLC conformed by histopathology were examined with diffusion weighting imaging (DWI). ADCs were calculated on multiple b-value imaging. Correlations between the ADCs and tumor cellularity, nuclear-cytoplasmic ratio and nuclear-kytoplasm ratio were analysed by Pearson rank correlation. Results: The ADCs of NSCLC correlated negatively with tumorous cellular density on multiple b-value imaging and as b was 300 s/mm2,which can achieve the best correlation (b=300 s/mm2, r=-0.792, P<0.01). There were inverse correlations between ADCs and nuclear-cytoplasmic ratio, nuclear- kytoplasm ratio (b=300 s/mm2, r=-0.739, P<0.01, -0.607, P=0.0187, respectively). Conclusions: Preliminary results revealed the ADCs of NSCLC had close correlation with tumorous histopathology characteristic.]]></description>
<pubDate>Mon,20 Jan 2014 00:00:00  GMT</pubDate>
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<title><![CDATA[Study of multi-modality MRI on dysplastic nodule with cirrhosis]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.3969/j.issn.1674-8034.2014.01.010</link>
<description><![CDATA[Objective: Study the imaging features of dysplastic nodule (DN) with cirrhosis by multi-modality MRI, to reveal the correlation between DN imaging features and pathological evolution mechanism. Materials and Methods: Fifteen patients with DN confirmed by pathology, laboratory tests, follow-up and several kinds of imaging examination. All patients underwent multi-modality MRI examination. Results: DN lesions showed high signal in T1WI by 80%, showed equal or low signal by 66.7% in T2WI. SNR, CNR value of the DN in T1WI and T2WI showed no obviously different from the liver parenchyma. DWI showed equal or low signal in 80% lesions as cancerous lesions in DN were high signal. All DN lesions were detected in SWI. DN cancerous lesion was slightly high signal in T1WI, with slightly low signal area in it while there was slightly high signal area in the lesion in T2WI. DN cancerous lesion was high signal in DWI. Enhancement time-signal intensity curve of DN showed almost the same with the liver parenchyma, which of cancerous lesions in DN obvious was similar to the curve of HCC. Contrast with the pathological findings, some HGDN could be diagnosed by image features. Conclusions: There was some correlation between DN imaging features and pathological evolution mechanism.]]></description>
<pubDate>Mon,20 Jan 2014 00:00:00  GMT</pubDate>
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<title><![CDATA[Dynamic contrast–enhanced MR imaging combined with T2*-weighted first-pass perfusion imaging in diagnosis of breast tumor]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.3969/j.issn.1674-8034.2014.01.011</link>
<description><![CDATA[Objective: To evaluate the value of breast T1WI dynamic enhancement scanning combined with T2*-weighted first-pass perfusion imaging in differential diagnosis of benign and malignant breast tumors. Materials and methods: 39 cases of benign or malignant breast tumors verified by pathology underwent T2*-weighted first-pass perfusion imaging and T1WI dynamic enhanced scan. We calculated the reduction rate of maximum signal strength in T2*-weighted first-pass perfusion imaging and the early enhancement rate of dynamic enhanced scan. We also drew the TIC of T2*-weighted first-pass perfusion imaging and T1WI dynamic enhanced scan. Results: There was a statistically significant difference in the reduction rate of the maximum signal strength in T2*-weighted first-pass perfusion imaging of breast neoplasms. When the scale of decrease of maximum signal which arrived 20% be identified as threshold, the sensitivity was 91.7%, specificity was 93.3%, and the accuracy is 92.3%. The difference of early enhancement rate in dynamic enhanced scan of breast neoplasms was not statistically different, but the type of dynamic enhancement curve had statistically significant difference. When the curve was outflow type, it could be defined as malignant standard (sensitivity was 62.5%, specificity was 93.3%, the accuracy was 74.4%). When TIC curve in T1WI dynamic enhanced scan of breast neoplasms was platform type (type II), the type of TIC curve in T2*-weighted first-pass perfusion imaging had statistically significant difference. Conclusions: T1WI dynamic enhanced scan combined with T2*-weighted first-pass perfusion imaging can be help to distinguish benign breast tumors from malignant ones. T2*-weighted first-pass perfusion imaging can improve the accuracy of qualitative diagnosis when TIC curve in T1WI dynamic enhanced scan of breast neoplasms was type II.]]></description>
<pubDate>Mon,20 Jan 2014 00:00:00  GMT</pubDate>
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<title><![CDATA[Quantitative assessment of hyperacute ischemic stroke onset time window]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.3969/j.issn.1674-8034.2014.01.012</link>
<description><![CDATA[Objective: To assess and quantify the ischemic onset time window of middle cerebral artery infarction hyperacute stroke of MCAO rat model at 7.0 T MRI diffusion weighted imaging (DWI) and by proton magnetic resonance spectrum (1H MRS). Materials and Methods: Diffusion-weighted imaging (DWI) and conventional T2WI were employed on 10 cases of MCAO rat model in measuring the average ADC lesion at different time periods. Quantification of local changes in the concentrations of metabolites within the lesions at different time zones was performed using magnetic resonance spectrum. Results: High signal area appeared half an hour after occlusion in DWI (100%). No abnormal signal was observed in 6 hours with general T2WI. 1H MRS display was consistent with elevated lactate (Lac) and reduced n-acetyl aspartic acid salt (NAA). Glutamate and taurine reached a maximum in rats 2 h after MCAO but began to decrease 3 h after MCAO. Conclusions: Hyperacute cerebral infarction can be pointed out with the application of T2WI, DWI and 1H MRS. These methods may also be used to assess quantitatively the ischemic onset time of a hyperacute stroke.]]></description>
<pubDate>Mon,20 Jan 2014 00:00:00  GMT</pubDate>
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<title><![CDATA[Cardiovascular magnetic resonance imaging: Part IV——The comparison of imaging features of cardiovascular magnetic resonance scanners with different field strength]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.3969/j.issn.1674-8034.2014.01.014</link>
<description><![CDATA[This article is the fourth section. Following the three previous sections, the current major types of cardiovascular magnetic resonance (CMR) scanner, 1.5 T and 3.0 T, were presented. 3.0 T system has played a role as the standardization for nervous system imaging in most units. But for body imaging, especially for cardiac imaging, there is much more challenging to perform imaging at 3.0 T than 1.5 T. However, it is the trend of development to perform CMR imaging in higher field strength due to the significant advantages. From the magnetic resonance physics to clinical application of CMR, the 1.5 T and 3.0 T CMR systems were compared in this article.]]></description>
<pubDate>Mon,20 Jan 2014 00:00:00  GMT</pubDate>
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<title><![CDATA[Research progress of rat brain glioma models]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.3969/j.issn.1674-8034.2014.01.015</link>
<description><![CDATA[Rat brain glioma models are capable of simulating biological characters of human brain glioma and they are widely used in the field of occurrence, development, treatment and intervention of human brain glioma. The sort of study used rat brain glioma models is more than ever. This review is focused on the variety and general features of rat brain glioma models, as well as their research progress at home and abroad.]]></description>
<pubDate>Mon,20 Jan 2014 00:00:00  GMT</pubDate>
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