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<title>Chinese Journal of Magnetic Resonance Imaging RSS feed</title>
<link>http://med-sci.cn/cgzcx/en/contents_list.asp?issue=201601</link>
<language>zh-cn</language>
<copyright>An RSS feed for Chinese Journal of Magnetic Resonance Imaging</copyright>
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<title><![CDATA[Study of brain structure in nomal plateau area adult with voxel-based morphometry]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2016.01.001</link>
<description><![CDATA[Objective: The aim of the study was to investigate the brain structure volumes alterations in born and raised high altitude (HA) (＞3000 m) normal adult by using voxel-based morphometry method (VBM). Materials and Methods: Two groups of adults participated in the study, including an HA group [8 males and 8 females, mean age=(21.81±2.07) years] and an age- and education-matched sea level (SL) group [7 males and 13 females, mean age=(21.85±1.90) years]. 3D-T1 structural images of all subjects who were underwent the whole brain scan were acquired. Then we used the VBM method to compare the whole brain GM and WM images differences between HA group and SL group. Results: HA acclimatization (vs. SL) showed increased gray matter volume in the left posterior cingulate, the left superior temporal gyrus,decreased GM volumes was found in the right insular lobe in highland group and we also found increased WM volumes in left thalamus, the right superior frontal gyrus, the lentiform nucleus, the left occipital lobe. Conclusions: The VBM method was applied to the analysis of the magnetic resonance structural images and it could objectively display the volume changes of specific brain areas in HA group and could get us a comprehensive evaluation of the impact of altitude hypoxia on brain structure.]]></description>
<pubDate>Wed,20 Jan 2016 00:00:00  GMT</pubDate>
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<title><![CDATA[Corticospinal tract injuries in subacute phase intracerebral hemorrhage: a diffusion tensor imaging study]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2016.01.002</link>
<description><![CDATA[Objective: The aim of this study was to evaluate the impairment of corticospinal tract (CST) at basilar part of pons level and its relationship with function level using diffusion tensor imaging (DTI) obtained in subacute phase intracerebral hemorrhage (ICH) patients. Materials and Methods: Twenty-six basal ganglia hemorrhage patients in subacute phase (7—21 days after the onset of ICH) and Glasgow Coma Scale score ＞12 were recruited in the study. Function level of all patients was evaluated by the National Institutes of Health Stroke Scale (NIHSS), modified Rankin scale (mRS), and Barthel Index (BI). DTI data were also obtained by 1.5 T MR scanner for the eigenvalues λ1、λ2、λ3 of CST at basilar part of pons. Fractional anisotropy (FA), mean diffusivity (MD) and λ23 were calculated according to these eigenvalues. Then we calculated the ratios of FA (rFA), MD (rMD), λ1 (rλ1) and λ23 (rλ23) between the affected and unaffected sides of the CSTs. Paired samples t test was applied for the comparisons of FA, MD, λ1 and λ23 between the affected and unaffected CSTs. Spearman correlation analysis was conducted between values of rFA, rMD, rλ, rλ23 and scores of NIHSS, mRS and BI. Statistical analysis was accomplished with SPSS 18.0 software. Results: The FA, MD and λ1 values of affected CST were significantly decreased (P＜0.05) and λ23 did not show any significant difference between the two sides (P＞0.05). The rFA was negatively correlated with NIHSS score (rs=–0.694, P=0.000) and mRS score (rs=–0.633,P=0.001), and positively correlated with BI score (rs=0.674, P=0.000). Conclusions: The integrity of affected CST of ICH patients in subacute phase was damaged, which was characterized by Wallerian degeneration. The index rFA of CSTs at basilar part of pons level could effectively evaluate the function impairment caused by CST damage.]]></description>
<pubDate>Wed,20 Jan 2016 00:00:00  GMT</pubDate>
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<title><![CDATA[Five cases about MRI characteristics of intracephalic gangliocytoma]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2016.01.003</link>
<description><![CDATA[Objective: Try to summarize some part of the MRI imaging features of intracephalic gangliocytoma. Materials and Methods: The MRI features of 5 cases of intracephalic gangliocytoma proved by surgery and pathology were investigated retrospectively, and the location of tumor, tumor shape, boundary, signal and enhancement were analyzed retrospectively and literature was reviewed. Results: Five cases of intracephalic gangliocytoma were located in the temporal lobe (n=4), cerebellar vermis (n=1), the shape of tumors showed round (n=3), a big cyst-solidary (n=1), and irregular (n=1). MRI signal of tumors were hypointense (n=4) or mildly hyperintense (n=1) on T1 and mildly hyperintense (n=4) or mildly hypointense (n=1) on T2, while signal confounding (n=4). CT and MRI suggested calcification (n=3). There were no edema (n=1), mildly edema (n=3) and moderate edema (n=1). The tumors were mild enhancement (n=2) and moderate enhancement (n=3). Conclusions: This group of cases about intracephalic gangliocytoma showed MRI findings diversely, but the basic consistent with the characteristics of benign tumor. The predilection sites were higher incidence of temporal lobe, and these cases showed higher incidence of calcification, more common in young people. All the manifest perhaps could do some help for the future clinical work of imaging diagnosis and differential diagnosis.]]></description>
<pubDate>Wed,20 Jan 2016 00:00:00  GMT</pubDate>
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<title><![CDATA[MRI appearances of carotid vulnerable plaques and prediction of the risk of ischemic stroke]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2016.01.004</link>
<description><![CDATA[Objective: To study the correlation between the MRI appearances of carotid vulnerable plaque and the risk of ischemic stroke by application of magnetic resonance imaging in high resolution imaging. Materials and Methods: Two hundred cases of carotid plaques were screened by B ultrasound examination and were performed Cervical vascular magnetic resonance imaging. Carotid plaques were divided into stable plaque group and vulnerable plaque group, then we analysed the plaque composition and the degree of luminal stenosis. Patients were followed up for 60 days with the occurrence of ischemic stroke. Results: Stable plaque group 112 cases, 2 cases of ischemic stroke occurred within 60 days. Vulnerable plaque group 88 cases, 26 cases of ischemic stroke occurred within 60 days. Conclusions: There was a significant correlation between carotid vulnerable plaque and ischemic stroke within 60 days. Carotid vulnerable plaque can be used as a predictor of short-term clinical symptoms in patients with carotid artery stenosis.]]></description>
<pubDate>Wed,20 Jan 2016 00:00:00  GMT</pubDate>
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<title><![CDATA[Benefits of the combination of MRI heavily-T2WI and contrast-enhanced T1WI pulse sequences to examine human lacrimal sac and nasolacrimal duct]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2016.01.005</link>
<description><![CDATA[Objective: To evaluate capability of the combination of magnetic resonance imaging (MRI) heavily-T2 weighted imaging (h-T2WI) and contrast-enhanced T1 weighted imaging (Ce-T1WI) pulse sequences revealing the anatomic details of normal or obstructed human lacrimal sac (LS) -nasolacrimal duct (NLD). Materials and Methods: Using 1.5 T MRI system, the normal and obstructed human LS-NLDs were imaged by h-T2WI and Ce-T1WI pulse sequences both with the fat-saturation technique. LS-NLD was scanned on its axial plane (AP) and coronal plane (CP). The thinnist slice thickness, consecutive sections (no spacing), static and dynamic scanning procedures were adopted. Results: Forty-six sides of normal LS-NLD (23 subjects) were imaged with the static scanning. Of them 24 sides were scanned with a combination of h-T2WI+Ce-T1WI+AP+CP, 6 sides with a combination of h-T2WI+Ce-T1WI+AP, 8 sides with a combination of h-T2WI+AP+CP, 8 sides with a combination of Ce-T1WI+AP+CP. The static scanning of 10 sides of obstructed LS-NLD (9 patients) was performed with a combination of h-T2WI+Ce-T1WI+AP+CP. The dynamic scanning of 20 sides of normal LS-NLD (10 subjects) was done with a combination of h-T2WI+AP. The normal and obstructed LS-NLDs were revealed vividly. (1)The normal LS-NLD. On the static scanning, their lumens were narrow and small, the size and shape of their lumens varied at different levels of LS-NLD, and NLD lumen was narrower and smaller than LS. On the dynamic scanning, the autonomous lumen changes (getting small or large) had been noticed. On cross sectional view, LS was long-ellipse (16 sides) or slit-shaped (30 sides), the junction was crescent, and NLD was short-ellipse (28 sides) or circular (18 sides). By h-T2WI, three-layer different signal intensities were revealed on a lot of images of LS-NLD, and 94.7% (36 /38 sides) and 31.2% (10/32 sides) of LS-NLDs showed this signal pattern on axial and coronal scanning respectively. The three layer signals represented respectively (a) contents (tear, tear film or air) in their lumens,(b) medial part of their wall that was smaller than a quarter of their wall thickness and (c) lateral part of their wall that was more than three-fourths of their wall thickness. The tear, the tear film and the air in their lemen gave the most hyper-intense signal, middle-intense signal and the most hypo-intense signal respectively. The medial part and lateral part wall gave a hypo- and middle-intense signals respectively. The medial part wall consists of the epithelium layer, blood capillary layer and postcapillary venule layer, and the latter both are embedded in the lamina propria. The lateral part wall is venous lacunae layer embedded in the lamina propria, too. Ce-T1WI was able to enhance obviously the signal intensity of LS-NLD wall, therefor to promote distinguishing their wall from lumen (or contents). (2) The obstructed LS-NLD. Location and extent of the obstructive lesions were revealed precisely in all of the obstructed LS-NLDs. One side was lumen stricture and 9 sides were lumen occlusion. A lot of liquid (or pus) had been accumulated in the proximal LS-NLD lumen of the obstruction site, the lumen was dilatated, its wall was thinned and only showed one signal intensity. The lumen stricture might be revealed like an “hourglass” pattern. The site of lumen occlusion lost the normal three-layer signal pattern. Conclusions: MRI h-T2WI combined with Ce-T1WI pulse sequences can vividly reveal the lumen (or natures of the contents), wall and route of the normal human LS-NLD in normal physiological condition, and even can reveal detailed layers of their wall. They also can reveal the precise location and extent of lesions in the obstructed LS-NLDs. The tissues with blood supply can be distinguished from one (or the contents) without blood supply by this way. The autonomous size change of the normal LS-NLD lumens is revealed by the dynamic h-T2WI. This combination of MR pulse sequences can achieve aims of other imaging methods which are used to reveal LS-NLD and their lesions, so it is likely to replace the other approaches of dacryocystography with the combination.]]></description>
<pubDate>Wed,20 Jan 2016 00:00:00  GMT</pubDate>
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<title><![CDATA[The value of diffusion-weighted MRI in the preoperative diagnosis and staging of tongue carcinoma]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2016.01.006</link>
<description><![CDATA[Objective: To investigate the potential value of diffusion weighted imaging (DWI) and the apparent diffusion coefficient (ADC) for preoperative diagnosis and staging of patients with tongue carcinoma. Materials and Methods: Thirty-four patients with tongue carcinoma underwent DWI in addition to routine MR imaging before therapy, of which 32 patients underwent surgical treatment. The staging accuracy by routine MRI and DWI was compared with surgical pathology as the reference standard. Results: (1) Estimating of lesion size and extent of infiltration, DWI-MRI was more accurate than routine MRI (P＜0.05). (2) Routine MRI diagnosed 45 lymph nodes metastasis and the calculated sensitivity, specificity, accuracy was 71.0%,96.0%, 88.9%. DWI-MRI detected 53 lymph nodes metastasis, and the obtained sensitivity, specificity, accuracy was 89.3%, 89.3%,98.0% 98.8%. There was no statistical significance between them. The mean ADC values of metastasis lymph nodes and benign nodes were 0.91 × 10–3 mm2/s and 1.65 × 10–3 mm2/s, respectively (P＜0.01). (3) Routine MRI made over diagnosis of 6 cases and DWI-MRI only 1 case. The accuracy of routine MRI was 82.0% and DWI was 97.0%. Compared with the two methods, there was no statistical significance between them.Conclusions: DWI was of certain advantages in displaying the range of lesion and the ADC value measurement could provide useful information for diagnosis of lymph node metastasis for tongue cancer. DWI could improve preoperative diagnosis and staging accuracy for the tongue cancer.]]></description>
<pubDate>Wed,20 Jan 2016 00:00:00  GMT</pubDate>
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<title><![CDATA[Application value of DKI in grading of extrahepatic cholangiocarcinoma]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2016.01.007</link>
<description><![CDATA[Objective: To evaluate the application value of diffusion kurtosis imaging (DKI) based D, K parameters in grading extrahepatic cholangiocarcinoma (EHCC) and compare their diagnostic potential. Materials and Methods: Thirty-five consecutive patients surgically resected and pathologically confirmed EHCC were included in this study. All patients underwent upper abdomen magnetic resonance imaging, including traditional magnetic resonance imaging and diffusion kurtosis imaging. The DKI derived parameters D, K were calculated by using post-processing software. Compared with histologic grade (well-differentiated, moderately differentiated and poorly differentiated adenocarcinoma), evaluating the association and compare the diagnostic potential of parameters by using receiver operating characteristic (ROC) analysis. Results: Thirty-five cases of EHCC include: grade Ⅰ(well-differentiated adenocarcinoma) 11 cases, grade Ⅱ(moderately differentiated adenocarcinoma) 11 cases and grade Ⅲ (poorly differentiated adenocarcinoma) 13 cases. Grade Ⅰ group lesions parameter D, K values were (1.56±0.08) ×10–3 mm2/s, 0.38±0.07. Grade Ⅱ group were (1.47±0.09) ×10–3 mm2/s, 0.51±0.08. Grade Ⅲ group were (1.39±0.07) ×10–3 mm2/s, 0.66±0.08. D and K values were significantly different in well, moderately and poorly differentiated adenocarcinoma (P<0.001, <0.001). With the reduction of histological differentiation degree, D value decreased, while K value increased (r=0.672, 0.848). ROC analysis demonstrated a higher area under the ROC curve value for K than for D for differentiating different pathological grade of EHCC (0.860 VS 0.951). Conclusions: K value of EHCC showed significantly diagnostic performance in differentiating different grade EHCC, and are helpful of pathologic degree in preoperative diagnosis.]]></description>
<pubDate>Wed,20 Jan 2016 00:00:00  GMT</pubDate>
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<title><![CDATA[Specimens of colorectal cancer in vitro MRI pathological control study for signs of lymph node metastasis]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2016.01.008</link>
<description><![CDATA[Objective: To summarize the metastasis signs of rectal cancer lymph node on high resolution MR and DWI, to explore the accuracy of MRI examination of benign and malignant lymph node. Materials and Methods: Fourteen patients who confirmed as rectal cancer by pathology and accepted total mesentery excision rectal cancer were included in the study, and their specimens were examined by high-resolution MRI and DWI. Then according to the pathological examination, analyze the high-resolution MRI manifestations and DWI parameters characteristics of metastasis lymph node. Results: There are 14 patients with rectal cancer were concluded in the study, specimens MRI detected 112 lymph node and postoperative pathology examination found metastasis lymph nodes 22, reactive lymph nodes 36, normal lymph node 53. Most metastasis lymph node is neither smooth edge, no uniform internal signals, compared with benign lymph nodes, the difference was statistically significant (P<0.05). Most metastasis lymph node is neither smooth edge, no uniform internal signals, compared with benign lymph nodes, the difference was statistically significant, P values were less than 0.05. The short diameter of reactive hyperplastic lymph node and metastasis lymph nodes are 0.47—0.96 cm, 0.52—0.96 cm respectively, they are greater than normal lymph nodes (0.25—0.72 cm), the difference was statistically significant (P<0.05), but the difference between the reactive hyperplastic lymph node and metastasis lymph nodes has no statistical significance (P>0.05). The ratio of short diameter and length diameter are 0.855±0.047 and 0.0273±0.006, the difference was statistically significant (P<0.05). The ADC values of metastatic lymph nodes is markedly lower than the normal lymph nodes [(0.722±0.047)×10–3 mm2/s:(0.868±0.064)×10–3 mm2/s], but with reactive hyperplastic lymph node (0.734±0.078)×10–3 mm2/s was no significant difference. Conclusions: The edge and internal signal of the lymph node within the rectal mesentery displayed clearly on high-resolution magnetic resonance imaging (MRI), it has high diagnostic value for the assessment of metastasis lymph node metastasis. DWI for distinguishing normal lymph nodes with metastasis lymph node has certain value, but to identify reactive hyperplastic lymph nodes with metastasis lymph nodes, it has no significant means.]]></description>
<pubDate>Wed,20 Jan 2016 00:00:00  GMT</pubDate>
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<title><![CDATA[Development and preliminary validation of the MRI scoring methods for the hip in juvenile idiopathic arthritis]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2016.01.009</link>
<description><![CDATA[Objective: To evaluate and develop MRI scoring system for the hip in juvenile idiopathic arthritis. Materials and Methods: We used Wanfang and PubMed to identify relevant published articles. We proposed a new MRI scoring method for the hip in JIA based on relevant articles. Retrospective studies of 92 JIA patients with hip involvement were analysed from January 2011 to June 2014. The intra-reader and inter-reader agreement (evaluated by intra-class correlation coefficients, ICCs) were determined for scores of MRI. Results: Only 5 literatures were qualified. Except joint effusion and total scores, Other lesions of developed MRI scoring method had good reliability, ICC＞0.60, P＞0.05. We got reversible and irreversible MRI signs. Reversible MRI signs: synovial hypertrophy, joint effusion, bone edema. Irreversible MRI signs: bony erosion, cartilage loss, epiphysis lesion, joint space narrowing, muscular inflammation. There was no differences between subtypes of JIA in hip MRI scorings, oligoarticular JIA scorings were 6 (0—17), systemic JIA scorings were 5 (0—21), polyarticular (rheumatoid factor negative) scorings were 7 (1—19), polyarticular (rheumatoid factor positive) scorings were 8 (1—15), enthesitis related JIA scorings were 4 (2—5). Arthritis or subclinical-arthritis of hips could be detected much earlier. Especially in history of arthritis of 4 or fewer joints group (χ2=16.80, P＜0.01) and in history of arthritis of 5 or more joints group (χ2=4.792, P=0.029). Conclusions: Developed MRI scoring method proved to be a simple and highly reliable assessment score in the evaluation of JIA disease of the hips.]]></description>
<pubDate>Wed,20 Jan 2016 00:00:00  GMT</pubDate>
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<title><![CDATA[Study on MRI-pathologic in lipoma arborescens and chronic synovitis adipose hyperplasia of knee joint]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2016.01.010</link>
<description><![CDATA[Objective: To investigate the typical MRI features of lipoma arborescens (LA) of the knee, this paper compares and analyzes it with chronic synovitis lipohypertrophy of imaging and pathology results. Materials and Methods: Retrospective analysis was performed in 14 cases including 4 cases with LA proved by pathological diagnosis and 10 with chronic synovitis lipohypertrophy with datas of MRI and pathology. Lesionectomy was performed in all patients and specimen were observed in HE staining. Results: Four of 14 cases were diagnosed with LA. The adipose tissue by which characterized “tufted”, “dendritic”or “fluffy”, mild synovial hyperplasia as well, were revealed by the MRI and pathologic results. Two cases can not only see clusters of mature adipocyte, but also scattered ones. The others diagnosed with chronic synovitis adipose hyperplasia, both in MRI and pathology, showed synovial hyperplasia obviously and adipose tissue with only a few scattered flocculent point, while one with less adipose tissue even could not be found. Coexisting osteoarthritis was seen in all cases. Conclusions: MRI and pathologic performances of LA and hronic synovitis adipose hyperplasia show diffuse fatty infiltration of the subsynovial connective tissue. They differ in the form and content of synovial fat. Meanwhile we considered LA to be a manifestation or evolution in different stage of chronic synovitis adipose hyperplasia.]]></description>
<pubDate>Wed,20 Jan 2016 00:00:00  GMT</pubDate>
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<title><![CDATA[In vivo detection of the reversal effects using rAd/p53 to human colon cancer in mice with diffusion-weighted magnetic resonance imaging]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2016.01.011</link>
<description><![CDATA[Objective: To investigate the potential of diffusion-weighted magnetic resonance imaging (DWI) to detect the reversal effects of rAd/p53 for 5-FU resistance of human colon cancer in vivo. Materials and Methods: One hundred nude mice with human colon cancer SW480/5-Fu (5-Fu resistance) were randomly assigned into four groups: control group, 5-FU group, rAd/p53 group, rAd/p53+5-FU. At 24 h, 48 h, 72 h, 120 h and 168 h after treatment, 5 mice were selected randomly from each group and given DWI examinations. Then these mouse models were sacrificed with an overdose of anesthetic. Their tumors were removed and detected apoptosis (TUNNEL). Results: The ADC values at the edge area of the tumor in rAd/p53 and rAd/p53+5-FU groups were significantly higher than that of the control groups at the observed time points (P<0.05). The area ratios of tumor cell apoptosis in the rAd/p53+5-FU and rAd/p53 group were larger than that of control groups at the observed time point. The area ratios of tumor cell apoptosis and the ADC values in the rAd/p53+5-FU group were larger than that of rAd/p53 group at the observed time point.The ADC values of tumors were positively correlated with the area ratios of tumor cell apoptosis. Conclusions: The ADC value can evaluate the reversal effects of drug resistance with rAd/p53 in early stage of therapy in vivo.]]></description>
<pubDate>Wed,20 Jan 2016 00:00:00  GMT</pubDate>
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<title><![CDATA[Feasibility of multiple-echo GRE-R2* to renals at 3.0 T MRI]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2016.01.012</link>
<description><![CDATA[Objective: To explore the feasibility of multiple-echo GRE- R2* to renals at 3.0 T MRI. Materials and Methods: A MR phantom which includes fifteen vials containing 0.2—3.2 mmol/L manganese chloride in hydrochloric acid solution, 51 healthy vonlunteers (Group A) with kidneys in-situ and 22 normal renals (Group B) transplanted were scanned by 3.0 T MRI, repeated protocols to the phantom and group A with kidneys in-situ one month later. Both phantom and in-vivo renals R2* were quantified by a well-trained physician using a CMR tools after MRI. Results: Phantom R2* was linearly correlated with its concentration in vials (r=0.999, P=0.000). Through the regressions procedure,a slope of 0.008 and an intercept of –0.050 were found. No statistic differences were found for R2* value between the first and second scanning on phantom (P＞0.05), The real and predicted concentration of phantom, R2* repeated scanning on phantom have a highly reliability respectively (ICCconcentration=1, ICCR2*=0.999). No statistic differences were found for gender and age between group A and B(P＞0.05). No statistic differences were found for the cortical and medullary R2* between left and right renal (P＞0.05). No statistic differences were found for kidneys R2* in group A between the first and second scanning (P＞0.05), It showed a well reliability respectively (ICCcortex=0.847, ICCmedullation=0.915). No statistic differences were found for renal R2* between group A and B (P＞0.05). However, renal R2* was dramatically higher in medullation than in cortex and there was statistic difference (P＜0.05). Conclusions: With CMRtools, multiple-echo GRE protocol is feasible for evaluating oxygenation in kidneys at 3.0 T MRI, it could provide a reliable evidence for clinic application to renals.]]></description>
<pubDate>Wed,20 Jan 2016 00:00:00  GMT</pubDate>
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<title><![CDATA[The application of non-Gaussion DWI model in body diseases]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2016.01.014</link>
<description><![CDATA[When perform diffusion-weighted imaging (DWI) at ultrahigh b-value, the standard monoexponential model analysis may not be suitable. Water molecules diffusion behaviors in the extracellular space away from Gaussian distribution, thus it is requiring a more sophisticated model for analysis the non-Gaussian behaviors of water. Diffusional kurtosis imaging (DKI) can describe this non-Gaussian diffusion effects of water and provide an additional parameter Kapp, which presumably reflects heterogeneity and irregularity of cellular microstructure, as well as the amount of interfaces within cellular tissue. A few studies have explored DKI outside the brain in rencent years. The most investigated organ is the prostate. Studies have shown that DKI can improve tumor detection and grading. A robust understanding of DKI is necessary for radiologists to better understand the meaning of DKI parameters in the context of different tumors and how these parameters vary between tumor types and in response to treatment. This article reviewed the basic principle, biological correlation, technique highlights and the clinical application in the body of DKI.]]></description>
<pubDate>Wed,20 Jan 2016 00:00:00  GMT</pubDate>
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<title><![CDATA[Progress of resting-state functional magnetic resonance imaging in bipolar disorder]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2016.01.015</link>
<description><![CDATA[Magnetic resonance imaging (MRI) is widely applied in assessing the changes of functional and structuralbrain, and it is being used as an important tool for clinical diagnosis and evaluation of bipolar disorder (BD). In this paper, the recent progress in studies of resting-state fMRI of BD is reviewed.]]></description>
<pubDate>Wed,20 Jan 2016 00:00:00  GMT</pubDate>
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