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<title>Chinese Journal of Magnetic Resonance Imaging RSS feed</title>
<link>http://med-sci.cn/cgzcx/en/contents_list.asp?issue=201801</link>
<language>zh-cn</language>
<copyright>An RSS feed for Chinese Journal of Magnetic Resonance Imaging</copyright>
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<title><![CDATA[Interhemispheric resting state functional connectivity in bipolarⅠeuthymia]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2018.01.002</link>
<description><![CDATA[Objective: Abnormalities in structural and functional brain connectivity have been increasingly reported in patients with bipolar disorder (BD) by recent neuroimaging studies. However, BD-related alterations in interhemispheric functional interaction are still largely unclear. Resting-state functional magnetic resonance imaging (rs-fMRI) approaches, which reveal patterns of coherent spontaneous fluctuations in the fMRI signal, provide a means to quantitatively detect interhemispheric functional interaction pattern. We examined interhemispheric resting-state functional connectivity (RSFC) and its relationships with clinical characteristics in bipolarⅠeuthymia using a recently validated approach, voxel-mirrored homotopic connectivity (VMHC). Materials and Methods: Euthymic subjects with bipolar I disorder (n=27) and matched healthy subjects (n=27) underwent resting-state functional magnetic resonance imaging scans. rs-fMRI data were co-registered to the high-resolution T1 symmetric anatomical template, and the homotopic resting state functional connectivity was computed for each subject. Results: Group comparisons revealed that patients exhibited lower VMHC than healthy subjects in inferior frontal gyrus (opercular part), Rolandic operculum, insula, putamen (P＜0.05, GRF corrected). Negative correlation was found between the duration of BD and VMHC in the inferior frontal gyrus and Rolandic operculum (r=-0.402, P=0.037; r=-0.402, P=0.038). Conclusions: These findings suggest substantial impairment of functional coordination between homotopic brain regions in bipolarⅠeuthymia. Inferior frontal gyrus and rolandic operculum may have a role in the chronicity of BD.]]></description>
<pubDate>Sat,20 Jan 2018 00:00:00  GMT</pubDate>
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<title><![CDATA[Regional homogeneity of white matter lesions in older people with fall risk: a resting state fMRI study]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2018.01.003</link>
<description><![CDATA[Objective: The application of resting state fMRI (rs-fMRI) was used for exploring the regional homogeneity in the aged who had white matter lesions (WMLs) with fall risks. Materials and Methods: The aged more than 60 years old with WMLs were included in study, according to the Tinetti Balance and gait analysis, all patients were divided into experimental group (Tinetti＜25) and contrast group (Tinetti≥25). Regional homogeneity (ReHo) values were calculated respectively and correlation analysis was conducted between ReHo values and mini mental state exam (MMSE) and Montreal cognitive assessment (MoCA) extracted from significantly different brain regions. Results: There was statistic significance in the score of MoCA (t=3.881, P＜0.01) and MMSE (t=4.041, P＜0.01) between two groups with WMLs. In subjects with risk of falls, the mean ReHo values of left superior frontal gyrus, right middle frontal gyrus, right inferior frontal gyrus decreased, and the mean ReHo values of right middle frontal gyrus, right inferior frontal gyrus were positively correlated with MMSE and MoCA, the mean ReHo values of left superior frontal gyrus was positively correlated with MMSE. The mean ReHo values of right supplementary motor area, left primary motor cortex, left dorsal posterior cingular cortex, left fusiform gyrus, left cerebellum 3, 4, 5, 6 region, right cerebellum 10 region increased, and were negatively correlated with MMSE and MoCA. Conclusions: In subjects with fall risk, the regional homogeneity changed, these differences were correlated with cognitive function.]]></description>
<pubDate>Sat,20 Jan 2018 00:00:00  GMT</pubDate>
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<title><![CDATA[Application of multimodal magnetic resonance imaging in the evaluation of gliomas]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2018.01.004</link>
<description><![CDATA[Objective: To investigate the application of multimodal magnetic resonance imaging in the diagnosis and grading of gliomas. Materials and Methods: Thirty patients of glioma with pathological and immune-histochemical confirmation, who underwent conventional and functional MRI were retrospectively enrolled in the study. Tumor enhancement, peritumoral edema, signal intensity of diffusion weighted imaging (DWI), intratumoral susceptibility signal intensity (ITSS) in susceptibility weighted imaging (SWI), perfusion in arterial spin labeling (ASL) and state of fiber bundles were compared in high grade gliomas and low grade gliomas. Fractional anisotropy (FA) value and apparent diffusion coefficient (ADC) value in diffusion tensor imaging (DTI) as well as choline (Cho) /creatine (Cr), N-acetyl aspartic acid (NAA)/Cr and Cho/NAA in 1H MR spectroscopy (MRS) were measured and calculated. The differences of all the above indexes in the two groups were statistically analyzed. Results: There were 15 HGG and 15 LGG. Peritumoral edema, ASL perfusion, fiber bundles state, ADC value and Cho/Cr, NAA/Cr, Cho/NAA between the two groups were significantly different (P＜0.05). Tumor enhancement, DWI signal intensity, ITSS and FA value were not significantly different (P＞0.05). The area under curve (AUC) of ASL perfusion, fiber bundle status, ITSS, ADC, Cho/Cr, NAA/Cr, Cho/NAA and FA were 0.889, 0.833, 0.778, 0.972, 0.972, 1.000, 1.000 and 0.486, respectively. The combined AUC of peritumoral edema, tumor enhancement and DWI signal intensity was 0.796. Conclusions: Multimodal MRI can provide comprehensive information of glioma, which plays a significant role in accurate diagnosis.]]></description>
<pubDate>Sat,20 Jan 2018 00:00:00  GMT</pubDate>
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<title><![CDATA[Relationship between focal white matter hyperintensity and minimal hepatic encephalopathy in patients with hepatitis B virus-related cirrhosis]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2018.01.005</link>
<description><![CDATA[Objective: To explore the relationship between focal white matter hyperintensity (WMH) and minimal hepatic encephalopathy (MHE) in patients with hepatitis B virus-related cirrhosis. Materials and Methods: Thirty-eight patients with hepatitis B virus-related cirrhosis, including 20 nHE and 18 MHE, admitted to our institution were included prospectively. All patients underwent neuropsychological tests, blood biochemical determinations and cerebral magnetic resonance imaging. Fluid attenuated inversion recover (FLAIR) images were reviewed for focal WMH by two neuroradiologists, independently. Those with Fazekas scale scores 0-1 were classified as no or mild focal WMH, while those with Fazekas scale scores≥2 were classified as moderate or severe focal WMH. nHE and MHE groups were compared concerning age, gender, duration of cirrhosis, Child-Pugh scale, venous blood ammonia level and the severity of focal WMH. Multivariate logistic regression analysis was performed to evaluate the independent predictor for MHE. The Spearman rank tests were performed to investigate correlation between the severity of focal WMH and cognitive function. Results: Cpmpared with the age and gender-matched nHE group, there were significantly more patients with moderate or severe focal WMH in MHE group (P＜0.01). However, duration of cirrhosis, Child-Pugh scale and venous blood ammonia level did not differ significantly between the two groups (all P＞0.05). Multivariate logistic regression analysis showed that moderate or severe focal WMH was the independent predictor for MHE (OR=18.62, 95% CI: 2.43—142.86, P＜0.05). Correlation analyses showed significant positive correlation between the severity of focal WMH and completion time of NCT-A (r=0.617, P＜0.01), significant negative correlations between the severity of focal WMH and scores of DST and digital span test (r=-0.695, P＜0.01, r=-0.558, P＜0.01). Conclusions: Moderate or severe focal WMH in cirrhotic patients is the independent predictor for MHE, which indicates the possibility of MHE.]]></description>
<pubDate>Sat,20 Jan 2018 00:00:00  GMT</pubDate>
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<title><![CDATA[MR evaluation of normal fetal cerebellar vermis development]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2018.01.006</link>
<description><![CDATA[Objective: By measuring normal fetal cerebellar vermis, adjacent structure and the angle value, calculate reference range, analyze development of different gestational age. Materials and Methods: MR images of 856 normal fetal heads in the middle and late pregnancy (from January 2011 to February 2017) were collected, separately measure vermis diameter, superior/inferior vermis height, area, vermis/posterior cranial fossa, vermis/anterior posterior diameter of the four ventricle, BV°, BT° to observe the vermis development and statistical analysis. Results: The overall and gestational age showed a linear positive correlation for linear growth, which the median sagittal anteroposterior diameter, vermis area and gestational age had the strongest correlation. Vermis/anterior posterior diameter of the four ventricle had the worst correlation. With the increase of gestational age, BV angle showed a decreasing trend, but BT was not correlated with the change of age. Conclusions: Fetal MR can  reliably depict vermis of anatomical structure, dynamically evaluate the development of the vermis according to the normative reference data.]]></description>
<pubDate>Sat,20 Jan 2018 00:00:00  GMT</pubDate>
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<title><![CDATA[Functional connectivity density alterations at resting state in neuromyelitis optica patients]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2018.01.007</link>
<description><![CDATA[Objective: Using a novel functional connectivity density (FCD) approach to investigate the strength of intrinsic connectivities alternations in neuromyelitis optica (NMO) patients at resting-state, and the correlation with clincal scores and duration. Materials and Methods: A total of 20 NMO patients and 20 sex- and age-matched healthy controls underwent resting-state functional MRI (rs-fMRI) examinations. Data of rs-fMRI were measured on DPARSFA (based on Matlab station) by using degree centrality method (threshold value was 0.25). Analysis of FCD map between the patient group and the control group were performed by two sample t test (P＜0.001, uncorrected, voxels＞30). Correlation analysis was performed for regions with FCD value statistically different in NMO with clinical parameters. Results: Compared with the control group, NMO patients showed significantly increased FCD in the left cerebellum crus and decreased FCD in the bilateral frontal lobe (BA 11), bilateral cerebellum 6 and left lingual gyrus. Moreover, the FCD values of the left cerebellum crus was correlated with duration (r=0.6, P=0.005). Conclusions: NMO patients have abnormal brain function network connection properties, which show that the increase or decrease of FCD in multiple brain functional areas may be related to the neuropathologic mechanism of the limb and cognitive dysfunction of NMO patients.]]></description>
<pubDate>Sat,20 Jan 2018 00:00:00  GMT</pubDate>
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<title><![CDATA[A research using resting-state fMRI and VBM for HFS]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2018.01.008</link>
<description><![CDATA[Objective: Using magnetic resonance imaging technique to explore the change of brain function and structure in patients with hemifacial spasm (HFS). Materials and Methods: This paper combined resting-state functional magnetic resonance imaging (rs-fMRI) and voxel-based morphometry (VBM) to investigate the spontaneous brain activity and structural differences between the 33 patients with HFS and the 33 healthy controls of gender matching. And the MRI data were analyzed by SPSS, SPM12 and Matlab. Two-sample t-tests were used to determine between-group differences and thresholds at P＜0.005 (voxel level), and FWE were corrected to P＜0.05 at the cluster level. The surviving clusters ＞30 were reported. Results: Compared to the controls, the patients with HFS exhibited significantly decreased regional homogeneity (ReHo) value in the cerebellum lobule Ⅵ, and decreased gray matter volume in the cerebellum lobule Ⅵ too. Conclusions: Our results showed that patients with HFS exhibited function and structure alteration in the cerebellum lobule Ⅵ, which would play an important role in pathology of HFS.]]></description>
<pubDate>Sat,20 Jan 2018 00:00:00  GMT</pubDate>
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<title><![CDATA[Diffusion tensor imaging to evaluate the value of treatment with cervical perivascular sympathectomy in children with cerebral palsy]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2018.01.009</link>
<description><![CDATA[Objective: To explpore the value of magnetic resonance diffusion tensor imaging (DTI) and diffusion tensor tracking (DTT), on evaluating the cerebral white matter recovery in children with cerebral palsy after cervical perivascular sympathectomy. Materials and Methods: Thirty children with hemiplegic cerebral palsy accepted clinical assessment and routine MRI and DTI examination before and after operation. The fractional anisotropy (FA) values for the regions including internal capsule and cerebral peduncle in the preoperative operation side and the opposite side, preoperative and postoperative, were measured and compared. 3D reconstruction of white matter tracts was employed. The gross motor function classification system (GMFCS) was used to evaluate the movement function of cerebral palsy in children. Paired sample t test was performed to compare the differences of FA values between the preoperative operation side and the lateral, preoperative and postoperative white matter. Spearman relativity analysis was performed to assess correlation between DTI parameters in different white matter fiber bundles and GMFCS in patients. Results: The FA values of white matter fiber bundle in different parts of the preoperative operation side were significantly lower of the preoperative contralateral, the differences were statistically significant (P＜0.01). Compared to preoperative, the FA values of white matter fiber bundle in different parts of the operation side were significantly increased in the six months after surgery (P＜0.01), the gross motor function had been improved. There was no statistically significant difference between the six months after surgery and the preoperative period of the FA value of white matter fiber bundles in different parts of the contralateral (P＞0.05). The clinical GMFCS in the patients were negatively correlated with the FA values (P＜0.01). Moreover, the relativity between the GMFCS and the FA value of internal capsule and cerebral peduncle were both higher (r=-0.933, P＜0.01; r=-0.873, P＜0.01). Conclusions: DTI combined with DTT can be used to quantitatively evaluate the postoperative recovery of white matter in children with cerebral palsy; it plays an important role in adjuvant clinical treatment and prognosis assessment.]]></description>
<pubDate>Sat,20 Jan 2018 00:00:00  GMT</pubDate>
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<title><![CDATA[The diagnostic performance of hepatocyte-specific Gadoxetic acid disodium (Gd-EOB-DTPA) for detection of small hepatocellular carcinoma: a Meta-analysis]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2018.01.010</link>
<description><![CDATA[Objective: To systematically review the diagnostic performance of hepatocyte-specific Gd-EOB-DTPA for small hepatocellular carcinoma (sHCC). Materials and Methods: The diagnostic tests which were used to evaluate the diagnostic performance of Gd-EOB-DTPA for sHCC, were searched and collected in several databases including PubMed, Web of Science, Embase, CNKI, CBM, Wanfang Data and VIP from January 2008 to February 2017. Two reviewers independently screened literature, extracted data, and assessed the risk of bias of included studies. Meta-analysis was performed by using Stata 12.0 software. Results: A total of 12 studies from four countries were included, involving 1685 hepatic nodules in 1127 patients. The results showed that, the pooled sensitivity, specificity, positive likelihood ratio, negative likelihood ratio, diagnostic odds ratio and corresponding 95% confidence interval of Gd-EOB-DTPA for sHCC were 0.95 (0.91, 0.97), 0.90 (0.83, 0.95), 9.84 (5.60, 17.28), 0.06 (0.03, 0.10), and 166.39 (73.66, 375.84), respectively. The area under curve of summary receiver operating characteristic (SROC) was 0.98 (0.96, 0.99). The results of subgroup analysis suggested that sample size was a significant factor that influenced the diagnostic specificity of EOB-MRI for sHCC (P＜0.01). Conclusions: Hepatocyte-specific Gd-EOB-DTPA is of highly value for diagnosis of sHCC, which deserves to be recommended for clinical practice in early detection and diagnosis. Further studies with larger sample size are in demand for improving the diagnostic specificity.]]></description>
<pubDate>Sat,20 Jan 2018 00:00:00  GMT</pubDate>
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<title><![CDATA[Unilateral hip 3.0 T MRI application in femoroacetabular impingement]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2018.01.011</link>
<description><![CDATA[Objective: The purpose of our study is to evaluate the value of 3.0 T MRI for the diagnosis of acetabular labrum injury in the patients with femoroacetabular impingement (FAI). Materials and Methods: From January 2015 to June 2017 imaging features of 60 patients with FAI confirmed by arthroscopy were analyzed retrospectively, and compared with the results of arthroscopy. Results: The sensitivity, specificity, accuracy, positive predictive value, and negative predictive value of MRI diagnosis of acetabular labrum injury were 78.9%, 100%, 80% , 100% and 20% respectively. The coincidence of MRI diagnosis of paralabral cyst, femoral head cyst, round ligament injury, herniation pit were 100%, and the coincidence of MRI diagnosis of cartilage injury was 8.3%. Conclusions: Unilateral hip 3.0 T MRI is of great value in the diagnosis of acetabular labrum injury in FAI patients.]]></description>
<pubDate>Sat,20 Jan 2018 00:00:00  GMT</pubDate>
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<title><![CDATA[Application of local shimming in whole body diffusion weighted imaging]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2018.01.012</link>
<description><![CDATA[Objective: To discuss the application of local shimming in whole-body diffusion-weighted imaging (WB-DWI) for improving the quality of imaging. Materials and Methods: Forty consecutive patients who underwent WB-DWI scans were included in this study. All of them received two kinds of WB-DWI scans, i.e. with local shimming and without local shimming at the cervicothoracic junction. After that, 3D maximum intensity projection (MIP) images were reconstructed to check the truncation artifact. Results: The truncation artifact significantly decreased in images with local shimming compared to those without local shimming. Their image quality showed statistical difference (P＜0.01). Conclusions: Local shimming has important significance in reducing truncation artifact and improving the image quality in WB-DWI.]]></description>
<pubDate>Sat,20 Jan 2018 00:00:00  GMT</pubDate>
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<title><![CDATA[The research progress of early diagnose of Alzheimer<sup><sup>,</sup></sup>s disease by resting state functional magnetic resonance]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2018.01.014</link>
<description><![CDATA[Alzheimer's disease is the most common type of senile dementia. Clinically, AD is mainly characterized by progressive memory loss and cognitive impairment.It has been irreversible when realizing, so early identification and preventing is crucial. In recent years, resting-functional MRI (rs-fMRI) based on blood oxygen level dependent (BOLD) has become a new means to explore the AD brain functional abnormity, a large number of studies have shown that local functional activities and connection anomalies in the associated brain regions of default mode network (DMN) in the AD, this paper reviews the application in the AD brain's function in terms of resting state BOLD-fMRI.]]></description>
<pubDate>Sat,20 Jan 2018 00:00:00  GMT</pubDate>
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<title><![CDATA[Application and development of multimodal MRI in the diagnosis of early AD]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2018.01.015</link>
<description><![CDATA[Alzheimer's disease (AD) is the most common degenerative disease of the central nervous system in middle-aged and elderly people. It is characterized by progressive cognitive impairment and non-behavioral cognitive impairment. In recent years, with the development of the magnetic resonance imaging, multimodal MRI, which including structural magnetic resonance imaging (sMRI), magnetic resonance spectroscopy (MRS), diffusion tensor imaging (DTI) and diffusion kurtosis imaging (DKI), susceptibility weighted imaging (SWI) and quantitative susceptibility mapping (QSM) and functional MRI (fMRI), plays a very important role in the diagnosis of early AD. The aim of this study was to review the application and development of the multimodal MRI in the diagnosis of early Alzheimer's disease.]]></description>
<pubDate>Sat,20 Jan 2018 00:00:00  GMT</pubDate>
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<title><![CDATA[Locating the coordinates of globus pallidus internus using MR imaging-based method in Parkinson<sup><sup>,</sup></sup>s disease surgery]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2018.01.016</link>
<description><![CDATA[Surgery for Parkinson's disease is an indispensable part among all kinds of treatments, especially for patient who has showed signs of drug resistance or side effects after five to eight years of medication history. Deep brain stimulation surgery taking globus pallidus internus (GPi) as target has become a common and effective way to treat Parkinson's disease. The precisely defined location of GPi target is the key point to perform a successful surgery. For achieving the goal of accurately locating surgery targets, GPi locating method experiences two stages from indirect Atlas-based method stage to direct MR imaging-based method stage, during which magnetic resonance imaging technology plays a pivotal role. The fast development of magnetic resonance imaging technology is the necessary prerequisite to direct MR imaging-based method. Based on these considerations above, this paper conducted a systematic review on both the GPi surgery target location and application of magnetic resonance imaging technology in Parkinson's disease surgery for last two decades.]]></description>
<pubDate>Sat,20 Jan 2018 00:00:00  GMT</pubDate>
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