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<title>Chinese Journal of Magnetic Resonance Imaging RSS feed</title>
<link>http://med-sci.cn/cgzcx/en/contents_list.asp?issue=202101</link>
<language>zh-cn</language>
<copyright>An RSS feed for Chinese Journal of Magnetic Resonance Imaging</copyright>
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<title><![CDATA[Study on the correlation between body dysfunction and the degree of pyramidal tract injury in acute ischemic stroke by using diffusion tensor imaging technology]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2021.01.002</link>
<description><![CDATA[Objective: To study the correlation between body dysfunction and pyramidal tract injury in acute ischemic stroke by using diffusion tensor imaging technology. Materials and Methods: Collect routine MRI scans, DWI, DTI examinations, fractional anisotropy maps (FA maps) and ADC maps generated from workstations automatically for patients with acute ischemic stroke during the acute phase of the disease. We selected 16 cases that the lesion just invade unilateral basal ganglia from acute ischemic stroke patients. Measure the FA values, ADC values, and fiber bundle numbers of the lesion area and the corresponding part of the opposite side of the brain, and calculate the difference between the healthy side and the affected side of the fiber bundle numbers. Use the Mimics software to measure the lesion volume, and use the national institutes of health stroke scale (NIH Stroke Scale, NIHSS), clinical medical muscle grading to evaluate the degree of functional impairment. Use statistical methods to study the differences in the number of fiber bundles, FA values, and ADC values on the affected side and the normal side; to calculate the correlation between the differences in fiber bundle numbers and the lesion volume, NIHSS score, and muscle strength score, to count all the positive manifestations of the nervous system in 16 patients. Diffusion tensor tractography (DTT) and 3D slicer software were used to reconstruct the fiber bundles of the lesions and the corresponding parts on the healthy side, and the morphological changes of the fiber bundles were compared and observed. Results: There was a statistically significant difference between the number of pyramidal tracts, FA and ADC on the affected side and the same part on the normal side by using paired t test (P＜0.05, 0.001, 0.005, 0.001, respectively ). There was a significant correlation between the difference in the number of fiber bundles and the lesion volume and muscle strength grade (r=0.632, P=0.009; r =-0.554, P=0.026), and there was a significant positive correlation between the lesion volume and NIHSS score (r=0.789, P=0.000). And the difference and correlation were statistically significant. There was no correlation between the difference in the number of healthy and affected side fiber bundles and NIHSS score (P=0.061), and there was no correlation between the degree of reduction in FA value and the degree of reduction in ADC volume (P=0.890). The shape of the affected fiber bundle was different from that of the healthy side. Some of the affected fiber bundles are compressed, deformed,displaced, and broken, and some of the fiber bundles on the normal side extend toward the affected side. Conclusions: In patients with acute ischemic stroke, there was a correlation between body dysfunction and the degree of vertebral tract injury. The larger the lesion volume, the more severe the pyramidal tract injury was, the more severe the degree of brain tissue damage was, and the more obvious the body dysfunction was.]]></description>
<pubDate>Wed,20 Jan 2021 00:00:00  GMT</pubDate>
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<title><![CDATA[Predictors of intracranial hemorrhage after mechanical thrombectomy in acute ischemic stroke]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2021.01.003</link>
<description><![CDATA[Objective: To investigate the predictors for the occurrence of intracranial hemorrhage (ICH) in acute ischemic stroke patients after mechanical thrombectomy (MT). Materials and Methods: In this retrospective study, one hundred and thirty-five acute stroke patients who were treated in our hospital from January 2017 to June 2019 were evaluated. All patients underwent MR examination after MT therapy. ICH was evaluated by brain CT or MR examination after MT within 24 hours. ICH was divided into symptomatic ICH (sICH) and non-sICH (patients without ICH and sICH). MRI data and other clinical data were recorded. Statistical methods were used to analyze the predictors of ICH and sICH after MT in acute ischemic stroke. Results: Compared with no ICH group (n=79), ICH group (n=56) had higher fasting blood glucose (129.08±18.87 vs 139.77±16.70), higher glycated hemoglobin (HbA1c) (5.57±0.34 vs 5.99±0.42) and larger DWI infarct volume (20.28±26.30 vs 5.99±0.42), there were significant differences between two groups (t=-7.974, P＜0.001; t=-6.421, P＜0.001; t=-2.970, P=0.004). The DWI infarct volume in sICH group (n=18) (52.21±50.23) was larger than that in non-sICH (n=117) (24.28± 29.99), the difference was statistically significant (t=-3.317; P=0.001). Spearman correlation analysis showed that fasting blood glucose (r= 0.554; P＜0.001), HbA1c (r=0.450; P＜0.001) and larger DWI infarct volume (r=0.309; P＜0.001) were positively correlated with ICH, DWI infarct volume (r=0.234; P=0.006) was positively correlated with sICH. Logistic regression analysis showed that fasting blood glucose [OR (95% CI): 1.233 (1.139 ─1.335), P＜0.001], HbA1c [OR (95% CI): 39.121 (7.537 ─203.052), P＜0.001] and larger DWI infarct volume [OR (95% CI): 1.025 (1.006─1.044), P=0.009] were independent predictors of ICH after MT; DWI infarct volume [OR (95% CI):1.018 (1.006─1.030), P=0.004] were independent predictors of sICH after MT. Conclusions: Comprehensive evaluation of fasting blood glucose, HbA1c and DWI infarct volume can effectively predict the occurrence of ICH and sICH after MT, and guide clinical individualized treatment and improve functional outcome.]]></description>
<pubDate>Wed,20 Jan 2021 00:00:00  GMT</pubDate>
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<title><![CDATA[The clinical value of T1 and T2 values in predicting brain glioma grading and cell proliferation activity]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2021.01.004</link>
<description><![CDATA[Objective: To investigate the diagnostic value of T1, T2 and enhanced T1 value in predicting glioma grading and cell proliferation activity. Materials and Methods: Thirty-six patients with glioma confirmed by surgery and pathology were retrospectively analyzed, including 21 patients with high grade glioma (HGG) and 15 patients with low grade glioma (LGG). All patients underwent Magic scan and Magic contrast-enhanced scan one week before surgery. T1 mapping and T2 mapping were generated before and after enhancement. T1 value before enhancement (T1-pre), T2 value before enhancement (T2-pre) and T1 value after enhancement (T1-Gd) were measured in the solid portion of the tumor and normal white matter in the contralateral mirror. The pathological grades and Ki-67 labeling index (Ki-67 LI) of the surgical specimens were measured. The correlation between Magic parameters and Ki-67 LI and the difference between HGG and LGG of Magic parameters and Ki-67 LI were analyzed, and the ROC curve was drawn. Result: T1-pre, T1 ratio before enhancement (ratio of T1-pre, rT1-pre), T1-Gd, T1 difference before and after enhancement (ΔT1), T1 value percentage change was significantly associated with Ki-67 LI (P＜0.05).The correlation coefficients r were 0.502, 0.331, －0.351, 0.537 and 0.473, respectively. T1-pre, ΔT1、T1 value percentage change, Ki-67 LI in HGG was significantly higher than LGG and T1-Gd, ratio of T1-Gd after enhancement (rT1-Gd) in HGG was lower than LGG. The differences were statistically significant (P＜0.05). The diagnosis efficiency for ΔT1 to distinguish HGG and LGG was best, the diagnostic threshold was 373.25 ms, area under the curve was 0.816, the sensitivity was 90.5%, and the specificity was 60%, P=0.001. Conclusions: Quantitative measurement of T1 value can be used to distinguish high grade glioma from low grade glioma, which has clinical value in predicting tumor cell proliferation.]]></description>
<pubDate>Wed,20 Jan 2021 00:00:00  GMT</pubDate>
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<title><![CDATA[Gender difference of gray and white matter surface area in major depressive disorder]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2021.01.005</link>
<description><![CDATA[Objective：The purpose of present study was to explore the sex differences in gray and white matter surface area of major depressive disorder (MDD) patients and the relationship between these differences and clinical manifestations in different gender. Methods：High resolution 3D T1WI data were collected of 61 MDD patients and 61 matched healthy controls (both groups were 25 males and 36 females) prospectively. FreeSurfer software was used to pre-process the 3D T1 data and obtained the gray and white matter surface area images of all brain regions. Two-factor ANCOVA model was used to analyze the differences of the surface area on gray and white matter among four groups and then post-hoc test was used to analyze the brain regions with differences between every two groups. Correlation analysis was used to analyze the gender differences regions of MDD and their clinical characterisitics. Result：The main effect of sex difference in the surface area of gray and white matter was located in bilateral superior frontal gyrus, middle temporal gyrus, left rostral middle frontal gyrus, lateral occipital gyrus. In addition, the white matter surface area of bilateral superior temporal gyrus, left precentral gyrus, insular, right pars triangularis gyrus, medial orbitofrontal gyrus, fusiform gyrus, inferior parietal gyrus, and the gray matter surface area of left supramarginal gyrus, right rostral middle frontal gyrus, precentral gyrus, inferior temporal gyrus, fusiform gyrus, rostral anterior cingulate gyrus, lateral occipital gyrus and inferi orparietal lobule also exhibited gender differences (P＜0.01, Bonferroni correction). Post-hoc test showed that the surface area of the above brain regions in female MDD group was smaller than that in male MDD group (P＜0.01, Bonferroni correction). Correlation analysis found that the gray matter surface area of right rostralmiddlefrontal (r=-0.398，P=0.049) and fusiform gyrus (r=-0.440，P=0.028) were negatively correlated with the HAMD scores, and the gray matter surface area of left middle temporal gyrus was negatively correlated with the illness duration in male MDD patients (r= -0.419，P=0.037). Conclusions：The current results showed gender effect on gray matter and white matter surface area between male and female MDD patients, but the brain regions do not completely overlap. These gender differences of surface area may be related to the different clinical manifestations and morbidity in male and female MDD patients.]]></description>
<pubDate>Wed,20 Jan 2021 00:00:00  GMT</pubDate>
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<title><![CDATA[A multimodal magnetic resonance study of the effects of acute alcohol on CBF and OEF in memory-related brain regions in young people]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2021.01.006</link>
<description><![CDATA[Objective: Three-dimensional pseudo-continuous arterial spin labeling (3D pCASL) and asymmetric spine echo-based echo plane imaging (ASE EPI) were used to study the effects of different doses of acute alcohol on cerebral blood flow (CBF) and oxygen extraction fraction (OEF) in the memory-related brain regions of healthy young people, and to analyze the relationship between CBF and OEF in memory-related brain regions after different doses of acute alcohol consumption. Materials and Methods: Twenty-nine young volunteers were fed with different doses of Chinese alcohol. After drinking, blood alcohol concentration (BAC) was measured. BAC≥ 0.04% was the low concentration group, BAC≥0.06% was the medium concentration group, and BAC≥0.08% was the high concentration group, respectively. All subjects were examined by the memory function test and brain MRI before drinking and 30 minutes after drinking. The data before drinking was as the control group. The values of CBF and OEF in left middle frontal gyrus, parietal lobe, occipital cortex, bilateral cingulate gyrus, hippocampus, amygdala and bilateral cerebellar hemisphere were compared before and after drinking respectively. Results: (1) Compared with pre-drinking, 30 minutes after drinking, the CBF of left middle frontal gyrus, parietal lobe, occipital cortex, bilateral cingulate gyrus, hippocampus, amygdala increased (P＜0.05), and the CBF of bilateral cerebellar hemisphere decreased (P＜0.05). The difference of CBF within mild, moderate and severe dose groups was statistically significant (P＜0.05) by multiple comparison of LSD-t test. (2) Compared with pre-drinking, 30 minutes after drinking, the OEF of left middle frontal gyrus, parietal lobe, occipital cortex, bilateral cingulate gyrus, hippocampus, amygdala decreased (P＜0.05), and the OEF of bilateral cerebellar hemisphere increased (P＜0.05). The difference of OEF within mild, moderate and severe dose groups was statistically significant (P＜0.05) by multiple comparison of LSD-t test. Conclusions: After acute alcohol, the CBF and OEF of the memory-related brain regions showed a negative correlation, and the brain oxygen supply and utilization were in dynamic balance. The changes of cerebral blood flow and cerebral metabolism information of memory-related brain regions after acute alcohol have certain significance in revealing the mechanism of alcohol on the memory-related brain regions.]]></description>
<pubDate>Wed,20 Jan 2021 00:00:00  GMT</pubDate>
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<title><![CDATA[Intravoxel incoherent motion magnetic resonance imaging detecting alterations on optic nerve in the patients with orbital tumor]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2021.01.007</link>
<description><![CDATA[Objective: To investigate the value of intravoxel incoherent motion (IVIM) magnetic resonance imaging in evaluating the degree of optic nerve injury in orbital tumors. Materials and Methods: Twenty-five patients with space-occupying lesions confirmed by imaging examination and 12 volunteers were enrolled in this study, the difference of apparent diffusion coefficient (ADC), slow ADC (D), fast ADC (D*), fractional of fast ADC (f) of the affected side optic nerve and the contralateral side were compared by paired t test, parameters and the asymmetry index (AI) of parameters of optic nerve between the patient group and the control group were compared by independent sample t-test. International standard visual acuity chart was used to measure visual acuity, 11 cases were impaired visual acuity, 14 cases were not. Results: The affected side optic nerve presented significantly decreased f compared to the unaffected side [f= (28.2±2.7)% , (46.4±3.0)% respectively; P=0.0015], the affected side optic nerve presented significantly decreased f compared to the control group [f= (28.2±2.7)% , (45.4±5.5)% respectively; P=0.002], the visual impaired patients presented significantly decreased D* compared to the not visual impared [D* =(26.6±7.0)×10－3 mm2/s, (62.5±11.0)×10－3 mm2/s respectively; P=0.023]; affected group optic nerve presented significantly increased AI of f compared to the control group (AI of f =0.26±0.06, 0.03±0.06 respectively; P=0.033); there was a low correlation between visual acuity and D* of affected optic nerve(r=0.462, P=0.02). Conclusions: The voxel incoherent motion parameter D* was superior to the conventional single-exponential ADC in evaluating the optic nerve function damage caused by orbital tumors, and can provide more abundant information.]]></description>
<pubDate>Wed,20 Jan 2021 00:00:00  GMT</pubDate>
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<title><![CDATA[Application of high resolution dynamic enhanced MR scan in TN staging and operation mode selection of rectal cancer before operationLIU Jinling]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2021.01.008</link>
<description><![CDATA[Objective：To investigate the application value of high resolution MRI dynamic enhanced scan in TN staging and operation mode selection of rectal cancer before operation. Materials and Methods：A retrospective analysis was performed on 154 patients with rectal cancer confirmed by surgery and pathology in our hospital. All the patients received high resolution dynamic enhanced MR scan before surgery and underwent tumor TN staging. According to the results of preoperative staging, the operative method was proposed, and the difference between the preoperative planned and the final operative method was compared. Results：Among the 154 patients with rectal cancer, the accuracy of T staging and N staging by high resolution MRI was 87.7％ and 38.9％, respectively, The coincidence rate between the proposed operation and the actual one was 95.5％, with no statistically significant difference (P=0.480). The proposed operation and the actual one were highly consistent (Kappa value=0.873). The coincidence rate between the proposed surgical method and the actual surgical method was 98.2％ in 117 patients with medium and high rectal cancer, and the proposed surgical method was highly consistent with the actual surgical method (Kappa value=0.915). In 37 cases of low rectal cancer, the coincidence rate between the proposed operation method and the actual operation method was 86.5％, and the proposed operation method was highly consistent with the actual operation method (Kappa value=0.643). Conclusions：High-resolution MRI dynamic enhancement scanning for sensitivity and accuracy of the preoperative T staging of rectal cancer specific degree is higher, and the pathological diagnosis phase close, to formulate the operation mode and the actual operation mode high consistency, high resolution MRI dynamic enhancement scanning for the preoperative T staging of rectal cancer and the selection of surgical procedure with high clinical application value.]]></description>
<pubDate>Wed,20 Jan 2021 00:00:00  GMT</pubDate>
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<title><![CDATA[Correlation between pancreatic fat deposition and abdominal fat distribution and essential hypertension based on MRI]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2021.01.009</link>
<description><![CDATA[Objective: To investigate the association of pancreatic fat with visceral adipose tissue (VAT) and subcutaneous adipose tissue (SAT), and hypertension. Materials and Methods: A total of 54 patients with hypertension and 108 control subjects who underwent an upper abdomen MRI scan with IDEAL-IQ sequence were included. Pancreatic tissue was segmented and whole pancreatic fat fraction (FF) were measured. VAT and SAT area were measured. VAT and SAT FF were recorded. Visceral/subcutaneous adipose tissue area ratio (V/S) was also calculated. Results: Patients with hypertension had higher whole pancreatic FF, VAT area, SAT area, V/S, VAT FF and SAT FF. Whole pancreatic FF has the highest diagnostic value in detecting hypertension (area under the curve, 0.816). The threshold of whole pancreatic FF of 10.15% showed a sensitivity of 75.9% and specificity of 81.5% for hypertension. Whole pancreatic FF showed a moderate correlation with VAT area (r＝0.541) and VAT FF (r＝0.561) and a weak correlation with SAT area (r＝0.280), SAT FF (r＝0.324) and V/S (r＝0.266). Conclusions: Hypertension is associated with higher whole pancreatic FF, VAT and SAT. Both increased area and FF of VAT and SAT are positively correlated with whole pancreatic FF.]]></description>
<pubDate>Wed,20 Jan 2021 00:00:00  GMT</pubDate>
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<title><![CDATA[Predicting clinically significant prostate cancer based on perilesional and intralesional MRI radiomics features]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2021.01.010</link>
<description><![CDATA[Objective: To explore value of perilesional volume (ILV) and intralesional volume (PLV) MRI radiomics features for the diagnosis of clinically significant prostate cancer (csPCa). Materials and Methods: One hundred and forty patients (train set: 112, testing set: 28) who underwent prostate MRI examination were included in that retrospective study. ILV and PLV were manually segmented on T2WI (T2 weighted imaging), ADC map and radiomics features were extracted. Radiomics features were selected via univariate analysis and least absolute shrinkage and selection operator (LASSO) combined with 10-fold cross validation. Prediction model was built based on LASSO regression and evaluated by ROC curve analysis, decision curve analysis (DCA). Results: AUC and accuracy of model in train set were 0.93 (95% CI: 0.88—0.98, specificity: 0.87, sensitivity: 0.89), 0.84 (95% CI: 0.76—0.90), respectively. AUC and accuracy of model in test set were 0.92 (95% CI: 0.81—1, specificity: 0.95, sensitivity: 0.69), 0.89 (95% CI: 0.72—0.98), respectively. Decision curve showed that if the cut-off point is between 0.01 and 0.83 or between 0.87 and 0.98, using that model has more net benefit than either the“positive-all”model or the“negative-all”model. Conclusions: ILV and PLV based MRI radiomics features is valuable for diagnosis of csPCa.]]></description>
<pubDate>Wed,20 Jan 2021 00:00:00  GMT</pubDate>
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<title><![CDATA[Probe of the central mechanism of analgesic effect of ozone water on patients with knee osteoarthritis pain based on rs-fMRI techniqueTIAN Mingyue]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2021.01.011</link>
<description><![CDATA[Objective: To explore the central mechanism of analgesic effect of ozone water on knee osteoarthritis (KOA) patients with chronic pain by resting state functional magnetic resonance imaging (rs-fMRI), so as to provide theoretical basis for ozone water treatment of KOA. Materials and Methods: Eighteen patients with KOA who met the inclusion criteria were treated with joint cavity irrigation with ozone water. Visual analogue score (VAS) and rs-fMRI scan were performed before and after ozone water treatment. Regional homogeneity (ReHo) t data analysis method was used to analyze the brain areas with significant changes in ReHo after ozone water treatment. Pearson correlation analysis was performed between the changed ReHo and the changed VAS score. Results: After treatment with ozone water, ReHo values in different brain regions such as middle occipital gyrus, superior occipital gyrus, cuneiform lobe and angular gyrus in KOA patients increased, while ReHo values in superior temporal gyrus, central sulcus cover and precentral gyrus decreased. The results of correlation analysis showed that there was a negative correlation between the changes of ReHo and VAS in the right insular after ozone water treatment. Conclusions: Ozone water therapy may treat pain in patients with KOA by regulating the function of temporal lobe, parietal lobe, frontal lobe and occipital lobe, while insular may be the critical brain area of ozone water analgesia.]]></description>
<pubDate>Wed,20 Jan 2021 00:00:00  GMT</pubDate>
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<title><![CDATA[Systematic analysis, and review of the literature of pelvic digit]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2021.01.012</link>
<description><![CDATA[Objective: The clinical and medical imaging features of pelvic digit were shared through systematic analysis of the literature. Materials and Methods: Retrieved from PubMed, Embase, The cochrane library, CJFD database, Viper network and WanFang database. The literatures included in this study were systematically analyzed. Results: A total of 28 case reports were included in the systematic analysis. Pelvic digit is usually asymptomatic and is often discovered accidentally. However, there have been reports of related clinical symptoms in the past. The most common site of pelvic digit is the iliac, and the pseudarthrosis is its characteristic feature. Conclusions: Most pelvic digits were discovered incidentally by image examinations due to other unrelated diseases. Imaging examination provides valuable information for the observation of the appearance, structure and adjacent relationship with the surrounding soft tissue of the pelvic digit. Recognition of this benign anomaly and make a differential diagnosis is important to avoid unnecessary investigation or intervention.]]></description>
<pubDate>Wed,20 Jan 2021 00:00:00  GMT</pubDate>
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<title><![CDATA[Research status and progress of HIV-related neurological cognitive dysfunction syndrome based on MRI]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2021.01.014</link>
<description><![CDATA[Human immunodeficiency virus (HIV), or acquired immunodeficiency syndrome (AIDS) virus, is a virus that causes defects in the human immune system. Combination antiretroviral therapy (cART) has transformed HIV from a rapidly fatal disease to a more manageable chronic disease. Therefore, the life expectancy of HIV-infected (HIV) individuals receiving cART is almost as long as that of HIV-uninfected (HIV-) individuals. After infection, HIV enters the brain and can cause HIV-related neurocognitive disease (HAND) after a period of time. Magnetic resonance imaging (MRI) techniques [including magnetic resonance spectroscopy (MRS), structural MRI (sMRI), diffusion tensor imaging (DTI) and functional magnetic resonance imaging (fMRI)] and positron emission tomography (PET) have been used in HIV individuals. This article will introduce in detail the application and research progress of various magnetic resonance imaging technologies and brain networks in HAND.]]></description>
<pubDate>Wed,20 Jan 2021 00:00:00  GMT</pubDate>
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<title><![CDATA[Research progress of diffusion magnetic resonance imaging in mild cognitive impairment]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2021.01.015</link>
<description><![CDATA[Mild cognitive impairment (MCI) is considered to be an intermediate state of normal aging and Alzheimer's disease (AD) and other types of dementia. Active intervention during the MCI stage can help improve cognitive function and slow down the progression of AD. Therefore, it is very necessary to find sensitive imaging markers for MCI diagnosis and progress monitoring. Diffusion magnetic resonance imaging technology can noninvasively detect changes in the microstructure of brain tissue by describing the diffusion movement of water molecules in the brain tissue, providing important information for the study of the pathological mechanism of MCI and the evaluation of the severity of cognitive impairment. In recent years, the continuous development of new technologies has provided additional value for MCI research. This article reviews the research of diffusion tensor imaging (DTI), diffusion kurtosis imaging (DKI), free water diffusion magnetic resonance imaging (FW diffusion MRI), neurite direction dispersion and density imaging technology (NODDI) in MCI.]]></description>
<pubDate>Wed,20 Jan 2021 00:00:00  GMT</pubDate>
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<title><![CDATA[Dynamic functional connectivity analysis and its application in neuropsychiatric disorders]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2021.01.016</link>
<description><![CDATA[Functional brain connectivity analysis based on resting-state functional magnetic resonance imaging has been widely used in the research of neuropsychiatric disorders, which includes static functional connectivity and dynamic functional connectivity (DFC). Functional connectivity has the characteristics of dynamic change with time, but static functional connectivity may not be sensitive enough to detect the alteration of neurofluctuations. DFC analysis has been implemented in order to reveal the mechanism of complex neural activities and it has made a breakthrough in many clinical studies. However, there is a lack of comparability among DFC methods, and their results in clinical application are different. In this paper, combing the methods of the DFC and the latest research results in neuropsychiatric disorders, we pointed out the improvement direction of DFC and introduced the applications prospect of DFC in diagnosis of clinical diseases.]]></description>
<pubDate>Wed,20 Jan 2021 00:00:00  GMT</pubDate>
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<title><![CDATA[MR diffusion imaging: research advances in prognosis prediction of gliomas]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2021.01.017</link>
<description><![CDATA[Glioma is the most common malignant tumor in central nervous system. The prognosis of glioma varies greatly with different pathological grades and genotypes. MRI diffusion imaging reflects the changes of tissue structure by detecting the micro movement of water molecules, which has important clinical significance for the prognosis prediction of glioma. Diffusion tensor imaging (DTI), diffusion kurtosis imaging (DKI), intravoxel incoherent motion (IVIM), stretched exponential model diffusion-weighted imaging (SEM DWI), ultra-high b-value DWI imaging and neurite orientation dispersion and density imaging (NODDI) can quantitatively detect the diffusion information of water molecules in tissues, reflect the heterogeneity of tumor and cell proliferation, which provides new ideas for accurately predicting the prognosis of glioma. This paper reviews the research progress of MRI diffusion imaging in predicting the prognosis of glioma.]]></description>
<pubDate>Wed,20 Jan 2021 00:00:00  GMT</pubDate>
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<title><![CDATA[Research progress of correlation between FLAIR vascular hyperintensity and ischemic stroke]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2021.01.018</link>
<description><![CDATA[Magnetic resonance imaging is an important tool for the diagnosis of acute ischemic stroke, and the study of various imaging signs has important clinical significance. Fluid attenuated inversion recovery sequence vascular hyperintensity (FVH) frequently encountered in acute ischemic stroke, are known to be associated with local hemodynamic disorders, which shows the loss of flow void effect on the FLAIR sequence, presenting high signal. In recent years, researches on the correlation between FVH and cerebral infarction have become hot topics. This paper reviewed the pathophysiological mechanism, scoring methods and clinical significance of FVH.]]></description>
<pubDate>Wed,20 Jan 2021 00:00:00  GMT</pubDate>
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<title><![CDATA[Research progress of magnetic resonance imaging technology in the detection, diagnosis and efficacy evaluation of pituitary tumors]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2021.01.019</link>
<description><![CDATA[With the development of magnetic resonance imaging technology, the detection rate of pituitary tumors is getting higher and higher, especially small pituitary tumors. Magnetic resonance imaging technology can detect pituitary tumors, and evaluate its nature, response to clinical treatment and prognosis. Different MRI examination methods will also increase the diagnosis rate of pituitary tumors or better evaluate the different nature of pituitary tumors. For example, artificial intelligence and imaging radiomics methods can detect the hardness of tumors. The apparent diffusion coefficient value is correlated with the consistency of tumor softness and hardness; Magnetization transfer imaging can distinguish prolactinoma from non-functioning adenoma; 3.0 T has a higher detection rate of pituitary tumors than 1.5 T MRI. New magnetic resonance imaging techniques such as magnetic resonance elastography can determine the hardness of pituitary tumors and provide important indicators for surgery. Meanwhile, different inspection techniques can also be used to predict the effects of treatment methods and the prognosis of diseases.]]></description>
<pubDate>Wed,20 Jan 2021 00:00:00  GMT</pubDate>
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<title><![CDATA[The pathogenesis of iron and oxidative stress in multiple sclerosis and advances in MRI]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2021.01.020</link>
<description><![CDATA[Multiple sclerosis (MS) is the most common inflammatory demyelinating disease in the central nervous system, and its pathogenesis is still unknown. In recent years, studies have shown that iron and oxidative stress are involved in the pathogenesis of MS, but the specific temporal and spatial dynamic changes have not been fully clarified. Therefore, the non-invasive quantitative evaluation of iron and oxidative stress in MS lesions with multi-parameter MRI is of great significance to reveal the different pathological characteristics of MS in different stages. This article reviews the potential pathogenic mechanism of iron and oxidative stress in multiple sclerosis and the corresponding research progress of MRI.]]></description>
<pubDate>Wed,20 Jan 2021 00:00:00  GMT</pubDate>
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<title><![CDATA[Research progress on brain fMRI and PET imaging of acupuncture at Taixi point]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2021.01.021</link>
<description><![CDATA[In recent years, medical imaging technology has been widely used in acupuncture Taixi (KI3) brain central effect mechanism research. According to the relevant literature reports, the application of functional magnetic resonance imaging and positron emission technology of acupuncture KI3 research mainly focused on the distribution of activated brain area, acupuncture mechanism analysis, single point and group point and so on. As a common acupoint in clinical practice, KI3 has remarkable curative effect with single use and compatibility. A large number of studies have shown that the mechanism of acupuncture KI3 and its related points to improve clinical efficacy is realized through the integration and coordination of multiple brain regions. Through reading the literature, this paper analyzes the overall research trend in this field, summarizes the achievements and shortcomings of related topics, and provides direction guidance for the follow-up scientific research work.]]></description>
<pubDate>Wed,20 Jan 2021 00:00:00  GMT</pubDate>
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<title><![CDATA[Research progress of functional magnetic resonance imaging in radiation-induced brain injury after radiotherapy of nasopharyngeal carcinoma]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2021.01.022</link>
<description><![CDATA[Nasopharyngeal carcinoma (NPC) is treated primarily by radiotherapy. Despite the continuous improvement of radiotherapy technology, radiotherapy of NPC will inevitably cause varying degrees of damage to normal tissues. Brain injury resulting from radiotherapy is one of the most common complications in patients with NPC following radiotherapy, which affects the life quality of patients seriously. Therefore, the early diagnosis of radiation-induced brain injury is particularly important. And the rapid development of functional MRI provides new methods for the early diagnosis of brain injury after radiotherapy of NPC.]]></description>
<pubDate>Wed,20 Jan 2021 00:00:00  GMT</pubDate>
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<title><![CDATA[Progress in the application of radiomics in head and neck diseases]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2021.01.023</link>
<description><![CDATA[Radiomics refers to the high-throughput extraction of large amounts of image features from radiographic images, which extracts more information from image-based features for evidence-based clinical diagnosis and better clinical decision making. In this series, the progress in the application of radiomics in head and neck diseases was reviewed in recent years, including disease diagnosis, efficacy evaluation, prognosis prediction, tumor genotypes, molecular markers, and deep learning application. The demerits of radiomics at this stage and its future development direction in medical imaging diagnosis were also summarized at the end of article.]]></description>
<pubDate>Wed,20 Jan 2021 00:00:00  GMT</pubDate>
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<title><![CDATA[Research status of DCE-MRI semi-quantitative and quantitative analysis in distinguishing benign and malignant cervical lymph nodes]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2021.01.024</link>
<description><![CDATA[Inflammation, tuberculosis, tumors, and metastasis can all lead to swelling of cervical lymph nodes. Accurate identification of benign and malignant lymph nodes plays an important role in clinical treatment. The neovascularization of malignant lymph nodes is one of the important factors for the occurrence and metastasis of malignant lymph nodes. DCE-MRI is a functional imaging method that uses a small molecule gadolinium contrast agent to evaluate microvascular permeability. It can accurately reflect the difference in permeability of benign and malignant lymph nodes through semi-quantitative and quantitative parameters, and provide more comprehensive diagnosis and treatment for clinical diagnosis and treatment. information. The author now reviews the research status of DCE-MRI semi-quantitative and quantitative analysis in the identification of benign and malignant cervical lymph nodes in the past five years at home and abroad.]]></description>
<pubDate>Wed,20 Jan 2021 00:00:00  GMT</pubDate>
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<title><![CDATA[Research progress of cardiac magnetic resonance in acute myocardial infarction]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2021.01.025</link>
<description><![CDATA[Acute myocardial infarction is a serious cardiovascular emergency with high morbidity and mortality. Although interventional therapy can effectively relieve symptoms in some patients, the area at risk and microcirculation injury during reperfusion are closely related to prognosis. With the rapid development of magnetic resonance technology, its application in acute myocardial infarction is becoming more and more mature. This paper reviews the latest research progress of cardiac magnetic resonance in acute myocardial infarction.]]></description>
<pubDate>Wed,20 Jan 2021 00:00:00  GMT</pubDate>
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<title><![CDATA[Research progress of radiomics based on MRI in breast cancer]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2021.01.026</link>
<description><![CDATA[Breast cancer is one of the most common malignancy in women worldwide, and also the main cause of death from cancer in women. Improving accuracy of its early diagnosis, the early predictions of prognosis and response to therapy are crucial issues of clinical practice. MRI is the common imaging tool in diagnosing breast cancer because of high sensitivity to soft tissues. MRI can provide more comprehensive diagnostic information compared to mammography and ultrasonography. Radiomics, defined as the high throughput extraction and analysis of quantitative features from imaging data, is a relatively new field of research. In recent years, it has become popular and increasingly used in oncology. This article reviews the progress of radiomics based on MRI in breast cancer.]]></description>
<pubDate>Wed,20 Jan 2021 00:00:00  GMT</pubDate>
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<title><![CDATA[Research progress of <sup>1</sup>H-MRS in breast cancer]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2021.01.027</link>
<description><![CDATA[Breast cancer is a kind of malignant tumor that poses a great threat to women's health, whose morbidity and mortality are on the rise globally. Proton-magnetic resonance spectroscopic (<sup>1</sup>H-MRI) is a kind of functional magnetic resonance imaging, can detect chemicals in living tissue, noninvasive monitoring of tumor occurrence and development. <sup>1</sup>H-MRI can not only combine with other sequences to improve the diagnostic ability of breast cancer, but also has the unique advantages of complementary diagnosis ability for dynamic contrast enhanced MRI (DCE-MRI ) negative breast cancer and evaluating the early efficacy of breast cancer after neoadjuvant chemotherapy (NAC). In this paper, the status, deficiencies and prospects of <sup>1</sup>H-MRI in breast cancer are reviewed.]]></description>
<pubDate>Wed,20 Jan 2021 00:00:00  GMT</pubDate>
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<title><![CDATA[Research progresses in MRI in acute obstructive kidney injury]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2021.01.028</link>
<description><![CDATA[Acute obstructive kidney injury refers to a decline in renal function caused by urinary tract obstruction. In early stage, most patients lack specific signs or symptoms other than renal angina. However, clinical common laboratory indexes, such as serum creatinine, are used to evaluate whether the sensitivity of renal function is lower, but unable to measure the changes of single renal function. Nevertheless, treatment delay can lead to irreversible renal injury. Along with the development of magnetic resonance imaging, MRI can not only identify the site, cause and degree of urological obstruction, but also be sensitive to the secondary pathophysiological changes after the urinary obstruction in the early stage. It can quantitatively and accurately evaluate the changes of single renal function. Therefore, most patients can be corrected through early diagnosis and intervention. MRI has become a substitute of non-invasive methods for evaluating the renal function after urinary tract obstruction via one-stop scanning of anatomy and function.]]></description>
<pubDate>Wed,20 Jan 2021 00:00:00  GMT</pubDate>
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<title><![CDATA[Application progress of MRI in diagnosis and treatment of discoid meniscus]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2021.01.029</link>
<description><![CDATA[Discoid meniscus is a kind of discoid fibrocartilage plate formed by the abnormal development of meniscus, which is the most common anatomical variation of the meniscus of the knee joint. Magnetic resonance imaging (MRI) as its non-invasive imaging method of choice, can clearly show the shape, size and signal changes of the discoid meniscus, and plays an important role in its diagnosis and treatment. This article combines several different MRI techniques to study the morphology and function of discoid meniscus, reviews the application and contribution of MRI in the diagnosis and treatment of discoid meniscus, and discusses the value of MRI in the diagnosis and treatment of discoid meniscus and future research directions.]]></description>
<pubDate>Wed,20 Jan 2021 00:00:00  GMT</pubDate>
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<title><![CDATA[Progress in magnetic resonance imaging application of acute muscle strain]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2021.01.030</link>
<description><![CDATA[Acute muscle strain is defined as an acute indirect muscle injury and is common in daily life. In clinical practice, it is difficult to accurately diagnose based on symptoms and physical examination. Conventional magnetic resonance imaging (MRI) has high soft tissue resolution and is critical for the diagnosis and prognosis evaluation of acute muscle strain. Novel MRI techniques developed in recent years, including muscle MR elastography (MRE), T2 mapping, magnetic resonance diffusion weighted imaging (DWI), diffusion tensor imaging (DTI) and magnetic resonance spectroscopy (MRS), make it possible to observe the micro structure of strained muscle and provide quantitative and objective evidence for the diagnosis of acute muscle strain. This article reviews the various MRI techniques for acute muscle strain.]]></description>
<pubDate>Wed,20 Jan 2021 00:00:00  GMT</pubDate>
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