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<title>Chinese Journal of Magnetic Resonance Imaging RSS feed</title>
<link>http://med-sci.cn/cgzcx/en/contents_list.asp?issue=201810</link>
<language>zh-cn</language>
<copyright>An RSS feed for Chinese Journal of Magnetic Resonance Imaging</copyright>
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<title><![CDATA[Status of radiomics in cerebral giomas]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2018.10.001</link>
<description><![CDATA[Radiomics can analyze, refine, and quantify medical imaging data, which is helpful for further understanding of molecular (genetic) pathology and clinical biology of tumors. This is instructive for the treatment and prognosis of the patients. This paper is to review the application and further progression of radiomics in cerebral glioma.]]></description>
<pubDate>Sat,20 Oct 2018 00:00:00  GMT</pubDate>
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<title><![CDATA[An update of radiogenomics based on MRI features in glioma]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2018.10.002</link>
<description><![CDATA[Brain gliomas are one of the malignant tumor in central nervous system. Gliomas are of high incidence and recurrence rate with poor prognosis. In recent years, the diagnosis of glioma has been prompt to molecular genetic level because of the increased recognize of tumoral molecular genetics. A new diagnostic guideline is proposed, with the tumoral molecular characterization being taken into account. MRI can be used to reflect the histopathology, cell metabolism and molecular genetic changes of tumor. In this paper, the application of MRI techniques in evaluating the molecular genetics of gliomas is reviewed.]]></description>
<pubDate>Sat,20 Oct 2018 00:00:00  GMT</pubDate>
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<title><![CDATA[Histogram analysis for quantitative dynamic contrast enhanced MRI in grading of glioma]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2018.10.003</link>
<description><![CDATA[Objective: This study aimed to quantitatively evaluate the value of dynamic contrast enhanced magnetic resonance imaging (DCE-MRI) in grading of glioma using histogram analysis. Materials and Methods: One hundred and twenty glioma patients were included with 28 low grade gliomas (LGG, grade Ⅰ and grade Ⅱ) and 92 high grade gliomas (HGG, grade Ⅲ and grade Ⅳ). Permeability parameters, including Ktrans, Kep, Ve, Vp, and perfusion parameters, including IAUGC, CBF and MTT, were derived from DCE-MRI by applying the modified two-compartment extended toft model. Unpaired t test and Mann-Whitney U test were used to compare the difference between DCE-MRI histogram parameters of different grade gliomas. The diagnostic efficiency, sensitivity, specificity and the corresponding diagnostic threshold value of different parameters were then compared by ROC. Results: There were significant differences of Ktrans, Kep, Ve, IAUGC and MTT between LGG and HGG (P＜0.05). The results of ROC showed that IAUGC and Ve had the best diagnostic performance (P＜0.05). The diagnostic efficiency of the 75th percentile of Ktrans had the most significant increase compare with the mean value. The 95th percentile of IAUGC had the best performance. Conclusions: Histogram analysis for DCE-MRI provides valuable information for glioma grading.]]></description>
<pubDate>Sat,20 Oct 2018 00:00:00  GMT</pubDate>
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<title><![CDATA[The influence of texture retrieving method for support vector machine with DCE MR images to grade glioma]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2018.10.004</link>
<description><![CDATA[Objective: This study aimed to investigate the influence of texture retrieving model of dynamic contrast enhancement magnetic resonance imaging (DCE-MRI) for SVM-based glioma grading. Materials and Methods: One hundred and seventeen glioma patients (pathology confirmed grade II/III/IV) receiving MRI scans were retrospectively included. The tumor image texture attributes were retrieved using three common texture retrieving models, including GLCM, GLRLM, and GLSZM models. Model-derived features were input into linear SVM scheme and SVM-recursive feature elimination (SVM-RFE) feature selecting strategies to compare the model-dependent grading accuracies that were further tested with leave-one-out cross-validation (LOOCV). Classification results were further analyzed by Graphpad Prism 6. Results: Gray level had no significant influence on classification performance (P=0.1589). Texture model had obviously contracted (P=0.0001). GLCM performed best in combination with gray level 32 and 256 by using the top 22 and 17 attributes, respectively (accuracy=0.79). Conclusions: When using DCE-MRI image textures based SVM classification of gliomas, GLCM model in combination with feature selection performed best and should be recommended for preoperative glioma grading.]]></description>
<pubDate>Sat,20 Oct 2018 00:00:00  GMT</pubDate>
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<title><![CDATA[Prediction of WHO grade Ⅱ glioma gene typing using diffusion kurtosis imaging]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2018.10.005</link>
<description><![CDATA[Objective: Using the magnetic resonance imaging (MRI) diffusion kurtosis imaging (DKI) to predict the isocitrate dehydrogenase (IDH) gene state of WHO grade Ⅱ brain gliomas. Materials and Methods: Clinical and imaging data of twenty-five cases patients with WHO grade Ⅱ gliomas were collected and proved by pathology. Patients underwent routine MRI and DKI scanning before surgery, measuring tumoral solid portion, peritumoral edema, and normal appearing white matter (NAWM) DKI parameter value, including fractional anisotropy (FA), mean diffusivity (MD), mean kurtosis (MK), axial kurtosis (Ka), radial kurtosis (Kr). The DKI parameters correction was made (tumor or edema parameters values divided by NAWM value) to obtain the rFA (ratio of FA), rMD (ratio of MD), rMK (ratio of MK), rKa (ratio of Ka), rKr (ratio of Kr) value. Postoperative specimens were made of wax blocks and analyzed by sanger gene sequencing. Twenty-five patients were divided into IDH-mutant (16 cases) and IDH-wild type (9 cases). DKI parameters values between the two groups were comparaed by independent sample t tests. The ROC curve was used to analyze the diagnostic value of each parameter value. Results: After the correction, the rFA and rMK value of the wild-type tumor in IDH were higher than IDH mutation, while the rMD value was lower than IDH mutated type, and the difference was statistically significant (P＜0.05). There was no statistically significant difference in the parameters of DKI in the two groups of patients after correction. The area under the ROC curve of the rMK was 75.7%, when the rMK value was 0.515, the sensitivity was 77.8%, and the specificity was 68.7%. The area under the ROC curve of rFA was 72.9%, when the rFA was 0.527, the sensitivity was 66.7%, the specificity was 93.7%. The area under the ROC curve of rMD was 75.7%, when the rMD was 1.261, the sensitivity was 87.5%, the specificity was 66.7%. Conclusions: The correction value of rMK, rFA, and rMD with WHO Ⅱ glioma is helpful to determine the state of IDH gene, and the sensitivity and specificity of the rMK and rMD value were higher.]]></description>
<pubDate>Sat,20 Oct 2018 00:00:00  GMT</pubDate>
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<title><![CDATA[Multi-modality MRI study of relationship between carotid atherosclerotic stenosis and cerebral hemodynamics]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2018.10.006</link>
<description><![CDATA[Objective: Multi-modality MRI technique was used to investigate changes in cerebral hemodynamics with the aggravation of carotid atherosclerosis. Materials and Methods: 39 patients with unilateral carotid artery stenosis were included in the experimental analysis. High-resolution magnetic resonance imaging (HR-MRI) was used to determine the degree of stenosis, while dynamic susceptibility contrast perfusion imaging (DSC-PWI) was performed to evaluate the hemodynamic changes in brain tissue. According to the degree of stenosis, patients were divided into four groups. The perfusion parameters were measured in all patients, including the temporal parietal and frontal lobe. It is analyzed whether there is statistical significance in each group of differences. Evaluated the correlation between stenosis and perfusion values. At the same time, the relative perfusion values of the temporal parietal lobe and the frontal lobe of each group were compared and analyzed. Results: In 39 cases, nine cases showed abnormal frontal perfusion, and 19 cases abnormal perfusion of the temporal parietal lobe, while they were mostly present in the severe and occlusion group. Cerebral hemodynamic abnormalities and changes in perfusion parameters were more likely to occur in the temporal parietal lobe than in the frontal lobe. (P＜0.05). Taking the temporal parietal lobe as an example, the degree of carotid artery stenosis is positively correlated with relative mean through time (rMTT), relative time-to-peak (rTTP), relative cerebral blood volume (rCBV) (P＜0.01). Conclusions: Severe carotid stenosis or occlusion may result in insufficient blood supply to the distal vessels, reduced perfusion of frontal and temporal parietal lobe.]]></description>
<pubDate>Sat,20 Oct 2018 00:00:00  GMT</pubDate>
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<title><![CDATA[The value of MR high resolution free-breathing radial VIBE in displaying the morphological characteristics of peripheral solid pulmonary masses]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2018.10.007</link>
<description><![CDATA[Objective: To evaluate initially the diagnosis capability of no radiation-dose radial VIBE in observing the morphological characteristics of peripheral solid pulmonary masses, with the routine-dose computer tomography as a reference standard. Materials and Methods: Forty-six patients, 49 peripheral solid pulmonary masses were prospectively enrolled. The average size of the masses was about (3.87±1.91) cm, standard dose CT and radial VIBE imaging were used. Two radiologists had observed MR and CT morphological characteristics of peripheral solid pulmonary masses (lobulation, speculation, pleural indentation, spinous process, cavitation, bubblelike attenuation, halo, mediastinal lymph node enlargement and calcification). According to whether the signs are displayed or not, CT images are divided into two kinds, and the MR images are evaluated by 5 point visual scoring system. With CT as a reference standard, the ROC was used to evaluate the display capability of radial VIBE in displaying the morphological appearance of peripheral solid pulmonary masses. Results:  Compared with CT, the sensitivity and specificity of radial VIBE in displaying morphological characteristics were as follows: lobulation 91.3% and 100%, respectively; speculation 90% and 78.9%, respectively; pleural indentation 62.5% and 76%, respectively; spinous process 91.1% and 83.3%, respectively; cavitation 100% and 100%; bubblelike attenuation 90%, 97.4%, respectively; halo 50%, 100%, respectively; enlarged mediastinal lymph node 94.4% and 90.3%, respectively; radial VIBE has not found these 4 cases which have calcification in CT. Conclusions:  Although not as efficient as CT, the morphological characteristics of peripheral solid pulmonary masses were well visualized on radial VIBE images, such as lobulation, spiculation, spinous process, cavitation, bubblelike attenuation and mediastinal lymph node enlargement, which can be used to evaluate the morphological characteristics of peripheral solid pulmonary masses. However, radial VIBE was less effective in displaying calcification.]]></description>
<pubDate>Sat,20 Oct 2018 00:00:00  GMT</pubDate>
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<title><![CDATA[Comparative study on three kinds of MRI sequence for cervical nerve roots with 3.0 T MRI]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2018.10.008</link>
<description><![CDATA[Objective:  To compare the applied value of three kinds of MRI sequence for imaging of cervical nerve roots with 3.0 T MRI. Materials and Methods: 37 cases need scanning cervical vertebra with 3.0 T MRI were observed, which were performed with conventional MR, three-dimensional double-echo steady state (3D-DESS), multi-echo data image combination (MEDIC) and 3D sampling perfection with application optimized contrasts using different flip angle evolutions(3D-SPACE), all of the images were used for postprocessing reconstruction, to evaluate three aspects included image quality and the display of normal cervical nerve roots, the display definition of depressed cervical nerve roots, the contrast noise ratio (CNR) between cervical nerve roots and adjacent tissue. Results:  Three kinds of MRI sequence were compared in pairs in three aspects, MR 3D-DESS exceeds MR MEDIC in both CNR of nerve root-vertebra and CNR of nerve root-cerebrospinal fluid. MR 3D-DESS exceeds MR 3D-SPACE in CNR of nerve root-vertebra, but MR 3D-SPACE exceeds MR 3D-DESS in CNR of nerve root-cerebrospinal fluid. MR 3D-SPACE exceeds MR MEDIC in CNR of nerve root-cerebrospinal fluid, but no statistical difference between MR 3D-SPACE and MR MEDIC in CNR of nerve root-vertebra. There were statistical differences for three kinds of MRI sequence were compared in pairs in three aspects of image quality, the MR 3D-DESS superior to the MR MEDIC, the image quality of MR 3D-SPACE was worst. For the display definition of depressed cervical nerve roots, there was no statistical difference between MR 3D-DESS and MR MEDIC, which compared with MR 3D-SPACE, they superior to MR 3D-SPACE, they were statistical difference. Conclusions:  MR 3D-DESS significantly outperformed the MR MEDIC and MR 3D-SPACE in aspects of showing the structure of nerve roots and diagnosing the compression of nerve roots, and same time, MR 3D-DESS had advantage in imaging of cervical nerve roots and clinical diagnosis of cervical nerve roots injury.]]></description>
<pubDate>Sat,20 Oct 2018 00:00:00  GMT</pubDate>
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<title><![CDATA[Application of abbreviated protocol of magnetic resonance imaging in breast cancer high-risk people]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2018.10.009</link>
<description><![CDATA[Objective: To evaluate the validity of two abbreviated protocol (AP) of MRI in comparison with a full diagnostic protocol (FDP) of MRI in the breast cancer high-risk people. Materials and Methods: Seventy-eight female participants with high-risk of breast cancer were recruited for the study, who were underwent MRI and surgical treatment. Two AP [AP-1: consisting of the first post-contrast subtracted (FAST) and maximum-intensity projection [MIP] images; AP-2: AP-1 combined with diffusion weight imaging (DWI)] and FDP images were analyzed separately, and the sensitivity, specificity, positive predictive value (PPV) and negative predictive value (NPV) of breast cancer detection were calculated. Results: Histological examination revealed 32 malignant lesions and 46 benign lesions. The average interpretation time of the AP-1 and AP-2 were (78±25) s and (91±29) s, while the average interpretation time of the FDP was (205±54) s (F=12.355, P＜0.05). The sensitivity of the AP-1, AP-2, and FDP were respectively 93.8%, 100%, and 100%, and the specificity of the three MR protocols were respectively 76.1%, 91.3%, and 93.5%. In addition, the PPV of the AP-1, AP-2, and FDP were respectively 73.2%, 88.9% and 91.4%, and the PPV of the three MR protocols were respectively 94.6%, 100% and 100%. There was no significant difference among three MR protocols in sensitivity of breast cancer (F=2.142, P＞0.05). However, the specificity of AP-1 was significantly lower than that of AP-2 (P＜0.05) and FDP (P＜0.05), while there was no difference between AP-2 and FDP (P＞0.05). Conclusions: The AP may be efficient in the breast cancer screening with high-risk, and FAST+MIP images combined with DWI of MRI are helpful to improve specificity of breast cancer detection.]]></description>
<pubDate>Sat,20 Oct 2018 00:00:00  GMT</pubDate>
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<title><![CDATA[Analysis of MRI signal characteristics of neonatal severe hyperbilirubinemia]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2018.10.010</link>
<description><![CDATA[Objective: To investigate the MRI features of neonatal severe hyperbilirubinemia and provide objective imaging evidence for clinic. Materials and Methods: 80 cases of hyperbilirubinemia from January 2015 to July 2017 in Baoji Municipal Central Hospital, those were divided into two groups, including 35 cases of high bilirubin group, 20 cases of bilirubin encephalopathy group and correlated with cranial MRI examination. Another option of 30 cases of physiologic jaundice neonatus, who received MR examination. The difference of T1WI signal intensity in the globus pallidus (GP), subthalamic nuclei (STN), thalamus (T) were observed and measured. To analyse the relationship between serum total bilirubin level and signal intensit. Results: The ratio between the globus pallidus and the thalamus (GP/T) and the ratio between subthalamic nuclei and the thalamus (STN/T) were significantly different in T1WI (F=15.854, P=0.000; F=14.057, P=0.000), while T2WI was not statistically significant (F=2.042, P=0.137; F=0.110, P=0.896). Analyze the receiver operating characteristic (ROC) curve of GP/T ratio and STN/T ratio in bilirubin encephalopathy group, area under curve was 0.824, 0.814, the best threshold was 1.56, 1.63, respectively. MRI follow-up of 10 children with bilirubin encephalopathy showed 4 cases with high signal of T2WI in the globus pallidus. Conclusions: When the magnetic resonance T1WI GP/T, SNT/T exceeds 1.56, 1.63 in neonatal severe hyperbilirubinemia, the occurrence of bilirubin encephalopathy should be highly vigilant; While the same region changes to T2WI high signal at chronic stage, the prognosis is poor.]]></description>
<pubDate>Sat,20 Oct 2018 00:00:00  GMT</pubDate>
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<title><![CDATA[Evaluation of PI-RADS V2 in diagnosis of prostate cancer by using 3.0 T MR]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2018.10.011</link>
<description><![CDATA[Objective: To explore the diagnostic value of prostate image report and data system version 2 (PI-RADS V2) score in the diagnosis of prostate cancer (Pca) by 3.0 T MRI and body coil. Materials and Methods: The mutli-parameter magnetic resonance imaging (Mp-MRI) and clinical data of 50 patients with Pca confirmed by pathology were retrospectively analyzed. The prostate was divided into 6 parts according to the cutting model. Two doctors evaluated the effective predefined partitions of the Mp-MRI prostate images, compared the scores of each partition with the corresponding pathological results of the subarea, analyzed the uniformity and diagnostic results. The sensitivity, specificity, accuracy, positive predictive value and negative predictive value were evaluated. Results: 50 cases were divided into 300 prostatic central glandular regions, of which 238 were effectively predefined, the results were consistent well. The results showed that when the PI-RADS V2 score was 4, the diagnostic accuracy was 79.2%, the sensitivity was 70.4%, and the specificity was 83.8%. Routine reading results: the accuracy was 72.7%, the sensitivity was 49.7%, and the specificity was 92.3%. Conclusions: The diagnostic accuracy of PI-RADS V2 is high, and the results are highly consistent. The diagnostic efficiency of PI-RADS V2 in diagnosing central adenocarcinoma of prostate is better than that of routine reading.]]></description>
<pubDate>Sat,20 Oct 2018 00:00:00  GMT</pubDate>
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<title><![CDATA[The application value of vessel wall magnetic resonance imagingin intracranial artery dissection]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2018.10.013</link>
<description><![CDATA[Intracranial artery dissection containing dissection (IAD) and dissection aneurysm, is an important etiology of ischemic or hemorrhagic stroke in young and middle-aged individuals. The diagnosis of intracranial artery dissection is challenging due to the small diameter and tortuous path of intracranial vessels. As a non-invasive and non-radioactive method, vessel wall magnetic resonance imaging (VWMRI) can demonstrate the characteristic signal of intimal flip or intramural hematoma, thus diagnosing vessel dissection directly or indirectly, and playing a crucial role in pathogenesis, clinical stage, treatment and prognosis. This paper will briefly overview the application value of vessel wall magnetic resonance imaging in intracranial artery dissection.]]></description>
<pubDate>Sat,20 Oct 2018 00:00:00  GMT</pubDate>
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<title><![CDATA[The application of different technologies in evaluating cerebral collateral circulation of acute ischemic stroke patients]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2018.10.014</link>
<description><![CDATA[Collateral circulation is significantly associated with the good outcome after endovascular treatment for patients with acute ischemic stroke caused by the acute occlusion of cerebrovascular. Acute ischemic stroke patients with favorable collateral circulation have higher rates of good neurological outcomes compared with patients with poor collateral circulation. A comprehensive assessment of collateral circulation in clinical practice plays an important role in the selection of treatment. This paper summarizes the application of collateral circulation evaluation with different technologies.]]></description>
<pubDate>Sat,20 Oct 2018 00:00:00  GMT</pubDate>
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<title><![CDATA[Research progress on the mechanism of tactile stimulation influencing the brain]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2018.10.015</link>
<description><![CDATA[Touch stimulates a series of sites and eventually activates the cerebral cor-tex to form a tactile response. The studies found that the main activated cerebral corte-xes were the primary somatosensory cortex (S1) and the secondary somatosensory cortex (S2), the other brain regions were anterior cingulate cortex and thalamus. The factors influencing the activation of brain regions were stimulating position, the pro-perties of stimulants, age, etc.]]></description>
<pubDate>Sat,20 Oct 2018 00:00:00  GMT</pubDate>
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<title><![CDATA[Advances in application of various artificial intelligence algorithms on tumor based on radiology]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2018.10.016</link>
<description><![CDATA[Accompany with the continuous development of computer algorithm and hardware, artificial intelligence (AI) has showed promising prospective in medical image, comparing to radiologist, AI owns extreme speed in diagnosis for certain diseases and have well enough accuracy in the meantime. This article is aimed to introduce the advances in application of various artificial intelligence algorithms in tumor based on radiology, in addition, pointing out the current deficiencies of AI, in order to provide assistances to doctor for the better transition of AI from researches to clinical application in the future.]]></description>
<pubDate>Sat,20 Oct 2018 00:00:00  GMT</pubDate>
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