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<title>Chinese Journal of Magnetic Resonance Imaging RSS feed</title>
<link>http://med-sci.cn/cgzcx/en/contents_list.asp?issue=202010</link>
<language>zh-cn</language>
<copyright>An RSS feed for Chinese Journal of Magnetic Resonance Imaging</copyright>
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<title><![CDATA[Brief comment on imaging mimicking pathology of heart diseases]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2020.10.001</link>
<description><![CDATA[The author briefly reviews the value of cardiac MRI in tissue characterization, in order to emphasize that MRI is the best method to realize imaging mimicking pathology in the future.]]></description>
<pubDate>Tue,20 Oct 2020 00:00:00  GMT</pubDate>
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<title><![CDATA[The standardized image interpretation and post-processing interpretation of SCMR: 2020 update]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2020.10.002</link>
<description><![CDATA[In the last issue, we interpreted the 2020 version of standardized cardiovascular magnetic resonance (CMR) imaging protocols published by Society for Cardiovascular Magnetic Resonance (SCMR). In this issue, we will further interpret the 2020 version of standardized image interpretation and post-processing. It is true that the clinical application of CMR is more and more extensive, but in view of the diversity of CMR techniques and quantitative parameters, agreement on specific standards for the interpretation and post-processing of CMR studies is required to ensure consistent quality and reproducibility of CMR reports. In order to provide relevant reference, in this article, we mainly interpreted the requirements and standards for image interpretation and post-processing and discussed the pitfalls of image analysis where appropriately.]]></description>
<pubDate>Tue,20 Oct 2020 00:00:00  GMT</pubDate>
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<title><![CDATA[The relationship between the abnormal trigeminal root structure and the changes of local brain activity in classic trigeminal neuralgia patients]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2020.10.003</link>
<description><![CDATA[Objective: The changes of anisotropy fraction (FA), mean diffusion coefficient (MD), axial diffusion coefficient (AD), radial diffusion coefficient (RD) and amplitude of low-frequency fluctuation (ALFF) of trigeminal nerve root were collected by resting-state functional magnetic resonance imaging (rs-fMRI) and diffusion tensor imaging (DTI) to explore the changes of trigeminal nerve root structure and local brain activity relevance. Materials and Methods: Twenty five patients with unilateral classical trigeminal neuralgia (CTN) (CTN group) and 20 healthy controls (HCs matched by gender, age and education years recruited from the community at the same time) were scanned with resting fMRI and DTI. The values of FA, MD, AD, RD in trigeminal nerve root and ALFF in brain area between the two groups were tested with independent t-test. The brain ALFF and trigeminal rez of patients in CTN group were analyzed correlation between DTI parameters (FA, MD, AD, RD) and visual analogue score (VAS) . Results: Compared with HCs group, ALFF values of bilateral cerebellum, bilateral fusiform gyrus, left inferior temporal gyrus, left inferior occipital gyrus, right superior occipital gyrus and right anterior central gyrus in CTN patients increased. Compared with HCs group, FA value of trigeminal nerve decreased (P＜0.05), MD value increased (P＜0.05), RD value increased (P＜0.05), AD value was normal (P＞0.05). There was a negative correlation between FA value and VAS score at rez of trigeminal nerve (r=-0.952, P＜0.05), and a positive correlation between MD value and VAS score (r=0.848, P＜0.05). ALFF value of bilateral cerebellum, bilateral fusiform gyrus, left inferior temporal gyrus, left inferior occipital gyrus, right superior occipital gyrus and right anterior central gyrus was positively correlated with the score (P＜0.05). FA value was negatively correlated with ALFF value of bilateral cerebellum, bilateral fusiform gyrus, left inferior temporal gyrus, left inferior occipital gyrus, right superior occipital gyrus and right anterior central gyrus (P＜0.05). Conclusions: There is a correlation between the trigeminal nerve local structure damage and the brain functional change areas (pain processing, motor function and emotional perception) in CTN patients.]]></description>
<pubDate>Tue,20 Oct 2020 00:00:00  GMT</pubDate>
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<title><![CDATA[The treatment effect of modified DWI-FLAIR mismatch guided thrombosis in wake-up ischemic stroke]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2020.10.004</link>
<description><![CDATA[Objective: To investigate the safety, efficacy and outcome influencing factors of thrombosis in wake-up ischemic stroke (WUIS) using a modified diffusion-weighted imaging (DWI)-fluid-attenuated inversion-recovery (FLAIR) mismatch allowing for partial FLAIR positivity. Materials and Methods: A total of one hundred WUIS patients from January 2016 to January 2020 were collected retrospectively. All patients underwent emergency craniocerebral MRI examination before treatment. Patients with modified DWI-FLAIR mismatch were treated with thrombosis therapy. Multiple logistic regression analysis was performed to evaluate the influencing factors of WUIS patients. Results: The rate of neurological improvement (NIHSS≥4 score) (54.69% vs 30.56%; χ2=5.402, P=0.023) and favorable outcome (mRS score) (39.06% vs 19.44%; χ2=4.075, P=0.048) in modified DWI-FLAIR mismatch group (n=64) were significantly higher than those in DWI-FLAIR match group (n=36), while there were no significant difference in neurological improvement (NIHSS≥4 score) and favorable outcome (mRS score) between FLAIR negative group and partial FLAIR positivity group in subgroup of modified DWI-FLAIR mismatch (P＞0.05). Multiple logistic regression analysis showed that intravenous thrombolysis (OR=1.266, 95% CI: 1.052—1.443, P=0.004), modified DWI-FLAIR mismatch (OR=1.076, 95% CI: 0.527—1.884, P=0.013), glycosylated hemoglobin on admission (OR=1.190, 95% CI: 0.459—4.925, P=0.038), neurological improvement (NIHSS≥4 score) (OR=1.120, 95% CI: 0.570—2.210, P=0.021) were independently associated with outcome at 3 months in WUIS patients. Conclusions: It is safe and effective to use the modified DWI-FLAIR mismatch allowing for partial FLAIR positivity to select the patients with wake-up ischemic stroke for intravenous thrombolysis.]]></description>
<pubDate>Tue,20 Oct 2020 00:00:00  GMT</pubDate>
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<title><![CDATA[3.0 T MRI determination of hippocampus volume, olfactory bulb volume and cognitive impairment in Alzheimer' s disease patients]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2020.10.005</link>
<description><![CDATA[Objective: To explore the correlation of 3.0 T MRI measurement of hippocampal volume, olfactory bulb volume, depth of olfactory groove and cognitive impairment. Materials and Methods: A total of 64 Alzheimer's disease(AD) patients admitted to the Zhongnan Hospital of Wuhan Univercity from October 2017 to December 2019 were selected as AD group. The patients were divided into moderate group (32 cases) and mild group (32 cases) according to Mini-Mental State Examination (MMSE) score, 32 normal healthy subjects were selected as reference, all participants were examined by MMSE and MRI, the data of hippocampus and olfactory bulb were analyzed. Results: The values of cognitive function, hippocampal volume and olfactory bulb volume were the lowest in the moderate group, followed by the mild group, and the highest in the normal group. The differences between the three groups were statistically significant (P=0.000). There was no significant difference in olfactory groove depth between the three groups (P=0.862). The sensitivity and specificity of hippocampal volume and olfactory bulb volume were 0.76/0.78 and 0.92/0.71 respectively. Conclusions: The hippocampus volume and olfactory bulb volume of AD patients decreased with the reduction of cognitive function, and MRI measurement of hippocampus volume was better than that of olfactory bulb.]]></description>
<pubDate>Tue,20 Oct 2020 00:00:00  GMT</pubDate>
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<title><![CDATA[Correlation between acute lacunar infarction and asymmetric white matter hyperintensities]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2020.10.006</link>
<description><![CDATA[Objective: Acute lacunar infarction (ALI) and white matter hyperintensities (WMHs) are important components of cerebral small vessel disease, both closely related. This study intends to explore the effect of asymmetric WMHs on the location of ALI. Materials and Methods: Sixty-one patients (41 were male and 20 were female, with an average age of 65.7±12.6 years) with ALI and WMHs were examined by MRI, including routine imaging, fluid attenuated inversion recovery (FLAIR), diffusion weighted imaging (DWI) and magnetic resonance angiograph (MRA). The WMHs of left and right hemisphere were assessed respectively by modified scheltens scale on FLAIR sequence. The baseline data of symmetric and asymmetric WMHs groups were compared, and to further analyze the correlation between the type of WMHs and the location of ALI. Results: Among the 61 patients, according to WMHs score, 33 cases were in symmetric WMHs group and 28 cases were in asymmetric WMHs group. There were no significant differences in age, sex, body mass index (BMI), hypertension, diabetes, smoking, stroke, homocysteine (Hcy) and onset time between the symmetric and asymmetric groups (P＞0.05). There was a significant difference in National Institutes of Health Stroke Scale (NIHSS) at admission between the two groups (P＜0.05). In 61 ALI lesions, 34 lesions were located in the left cerebral hemisphere and 27 lesions in the right cerebral hemisphere. There was no significant difference between the cases of left and right hemisphere in the symmetric WMHs group (P＞0.05). In left asymmetric WMHs group (13 cases), ALI in the left hemisphere was more than that in the right hemisphere (P＜0.05). In right asymmetric WMHs group (15 cases), ALI in the right hemisphere was more than that in the left hemisphere (P＜0.05). In addition, most of the ALI in the center of the semicircular circle and the lateral ventricle were located at the edge of the WMHs. Conclusions: Cerebral hemisphere with severe white matter injury is more prone to acute ischemia in patients with asymmetric WMHs, and the ischemic lesion is mostly located on the edge of WMHs.]]></description>
<pubDate>Tue,20 Oct 2020 00:00:00  GMT</pubDate>
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<title><![CDATA[Application of contrast-enhanced MRI combined with DWI in the diagnosis of atypical hepatic abscess and hepatic metastatic tumor]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2020.10.007</link>
<description><![CDATA[Objective: To investigate the diagnostic value of contrast-enhanced magnetic resonance imaging (CE-MRI) combined with diffusion weighted imaging (DWI) in the diagnosis of atypical liver abscess and liver metastases. Materials and Methods: Retrospective analysis from January to December 2019 in Binzhou People's Hospital, 12 cases of atypical liver abscess and 11 cases of liver metastatic tumor were finally enrolled into the group, with a total of 43 lesions, MRI plain scan, DWI sequence and MR enhanced scan were performed in all cases, and all cases were confirmed by histological or clinical follow-up. It was divided into two groups, CE-MRI and CE-MRI combined with DWI, and the signal characteristics and enhancement modes of the lesions were analyzed and compared. Apparent diffusion coefficient (ADC) values of cystic and solid components of atypical liver abscess and metastatic tumor were compared. Results: The accuracy of CE-MRI in the diagnosis of atypical liver abscess and liver metastasis was 68.42% and 66.67%, respectively, and the accuracy of CE-MRI combined with DWI in the diagnosis of atypical liver abscess and liver metastasis was 94.73% and 87.50%, respectively, which were both higher than that of CE-MRI alone. The ADC values of cystic components of atypical liver abscess and liver metastatic tumor were about (1.18±0.04)×10-3 mm2/s, (2.02±0.17)×10-3 mm2/s, P＜0.01, showing statistical differences; The ADC values of solid components of liver abscess and liver metastasis were approximately (1.58±0.10)×10-3 mm2/s, (0.91±0.10)×10-3 mm2/s, P＜0.01, with statistical differences. Conclusions: CE-MRI combined with DWI has more advantages in the diagnosis of atypical liver abscess and liver metastases.]]></description>
<pubDate>Tue,20 Oct 2020 00:00:00  GMT</pubDate>
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<title><![CDATA[The resting-state fMRI study of interhemispheric voxel-mirrored homotopic connectivity in patients with primary dysmenorrhea]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2020.10.008</link>
<description><![CDATA[Objective: The present study aimed to investigate interhemispheric voxel-mirrored homotopic connectivity (VMHC) changes in patients with primary dysmenorrhea (PDM) applied by VMHC methods based on resting-state functional magnetic resonance imaging (rs-fMRI). Materials and Methods: Thirty-two patients with PDM and thirty-eight healthy female volunteers were chosen as research object. We collected the clinical data of two groups including basic demographic information, visual analogue scale for pain and anxiety, accompanying symptom score of dysmenorrhea and performed rs-fMRI. The VMHC value differences between two groups were analyzed, while the brain regions with group differences were further used to study correlation with clinical parameters. Results: Compared to the healthy controls, PDM patients demonstrated significantly increased VMHC values in the bilateral subgenual cortex/orbitofrontal region (Gaussian random field corrected, voxel P＜0.001, cluster P＜0.05, two tailed). Conclusions: Enhanced homotopic connectivity of bilateral subgenual cortex/orbitofrontal region was found in patients with PDM, which may provide a new perspective and objective imaging evidence for the central mechanism of PDM production and regulation.]]></description>
<pubDate>Tue,20 Oct 2020 00:00:00  GMT</pubDate>
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<title><![CDATA[Quantitative analysis between knee’s structural features and symptoms for the patients with knee osteoarthritis using random forest model]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2020.10.009</link>
<description><![CDATA[Objective: To investigate whether these imaging based on quantitative features can predict the symptoms of the knees and to evaluate which of these features show the highest predictive value in each distinct knee symptom. Materials and Methods: Five hundred and fifty-one subjects from Osteoarthritis Biomarkers Consortium of Foundation for the National Institutes of Health (FNIH) project in the osteoarthritis initiative (OAI) were included and divided into training and test sets. A total of 153 structural features from 5 quantitative structural feature sets and the Western Ontario and McMaster Universities (WOMAC) osteoarthritis index were included to access the structural characteristics and the symptom of the knees joints, respectively. Correlation analysis and minimum-redundancy maximum-relevance (mRMR) method were used to screen the structural features. Finally, four random forest (RF) regression model were constructed to predict the four WOMAC symptom scores of the knees joints based on the selected structural features, respectively. Results: The structural image features that affect the different symptoms (physical function, pain, stiffness) of the knee joint are manly concentrated at the medial part of the femur and tibia. The constructed predictors showed good feasibility and accuracy: the R-squared of the four predictors were all above 0.9 in both training and test sets. The mean absolute errors (MAEs) and mean squared errors (MSEs) of the pain and stiffness predictors were all restricted to below 0.5 in both training and test set, while the MAEs and MSEs of the physical function and total scores predictors were 0.5296/2.2727, 0.4449/7.8488 in training/test sets, and 1.4167/3.3498, 3.1651/16.3974 in training/test set. Conclusions: Constructed random forest model can be effectively used to predict and evaluate knee joint symptom, and the selected structural features can be future used as potential biomarkers in the knee joint symptom evaluation and treatment guiding.]]></description>
<pubDate>Tue,20 Oct 2020 00:00:00  GMT</pubDate>
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<title><![CDATA[In vitro study of SR-A targeted multimodal nanoparticles for the detection of atherosclerotic vulnerable plaques]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2020.10.010</link>
<description><![CDATA[Objective: To prepare a dualmodal molecular probe targeting scavenger receptor A (SR-A) loaded with dextran sulfate (DS), and to investigate its magnetic resonance (MR)/enhanced photoacoustic (PA) imaging and targeting ability in vitro. Materials and Methods: Nanoparticles [poly (lactic-co-glycolic acid), PLGA]-Fe3O4-DS were synthesized using double emulsification method and electrostatic adsorption method. The physicochemical properties and the MR/PA imaging capability were observed in vitro. The targeting efficiency of molecular probes for activated macrophages were evaluated. Results: The prepared PLGA-Fe3O4-DS nanoparticles have a regular shape, uniform size, and good dispersibility. The average particle diameter is 263.93±21.38 nm, the Zeta potential is -20.63±2.61 mV, and the DS connection rate is 90.06%. Nanoparticles have a good negative enhancement effect on magnetic resonance imaging. With the increase of its concentration, the photoacoustic signal gradually increases. Compared with the non-targeted group (PLGA-Fe3O4), the PLGA-Fe3O4-DS nanoparticles accumulated in large numbers around the nucleus after co-incubation of nanoparticles with activated macrophages. Conclusions: The PLGA-Fe3O4-DS nanoparticles were successfully prepared, which have good MR/PA imaging capabilities and high affinity for SR-A, providing the potential of analyzing the pathophysiological mechanism of receptors in the development of atherosclerotic plaques at the molecular level.]]></description>
<pubDate>Tue,20 Oct 2020 00:00:00  GMT</pubDate>
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<title><![CDATA[Study of Gd-EOB-DTPA T1 mapping in quantitatively staging hepatic fibrosis in a rabbit model]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2020.10.011</link>
<description><![CDATA[Objective: To explore parameters obtained by Gd-EOB-DTPA T1 mapping and extracellular volume fraction in evaluating hepatic fibrosis (HF) in a rabbit model. Materials and Methods: One hundred rabbits were randomly divided into two groups: the HF group (n=80) and the control group (n=20). The HF model was established by carbon tetrachloride (CCl4) in our experiments, whereas control rabbits received a subcutaneous injection of normal saline. After completing T1 mapping imaging, rabbits underwent pathological examination to determine the HF stage using the metavir classification system. Then, quantitative parameters including T1native, T110 min, T120 min, ECV10 min and ECV20 min were measured and compared among the different HF stages using spearman correlation coefficients and receiver operating characteristic curve. Results: In all, 14, 19, 15, 19, 18 rabbits had stage F0, F1, F2, F3 and F4, respectively, were included in this study. T1native (r=0.685), T110 min (r=0.428), T120 min (r=0.818), ECV10 min (r=0.278), and ECV20 min (r=0.766), increased with HF stage progression (P＜0.001). The AUC of T120 min was higher than that of other quantitative parameters, with an AUC of 0.90, 0.93, 0.93 and 0.92 for staging≥F1, ≥F2, ≥F3, ≥F4, respectively. Conclusions: T1 mapping parameters and ECV fraction are closely associated with HF progression, indicating that this may be a promising method for quantitatively differentiating HF.]]></description>
<pubDate>Tue,20 Oct 2020 00:00:00  GMT</pubDate>
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<title><![CDATA[Evaluation the staging of rabbits’ liver fibrosis using diffusion kurtosis imaging: A pilot research]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2020.10.012</link>
<description><![CDATA[Objective: To investigate the diagnostic value of the quantitative diffusion kurtosis imaging (DKI) in the staging diagnosis of rabbits’ liver fibrosis. Materials and Methods: Thirty-five healthy male rabbits were divided into experimental group (n=30) and control group (n=5) by subcutaneous injection of 50% CCl4 in olive oil. Rabbit models were scanned by a 3.0 T MR scanner (Discovery MR750W, GE, Healthcare, USA). GE AW4.6 Workstation and SPSS 21.0 help to evaluate the correlation between quantitative analysis of DKI and METAVIR staging. Results: With increasing stage of liver fibrosis, FA, MK value increased (r=0.499, 0.653, P＜0.01) and MD value decreased (r=-0.537, P＜0.01). And MD value was the best parameter for distinguishing F0 from F1-F2, F0 from F3-F4 with areas under curve (AUC) of 0.886, 0.975 and MK value was the best parameter for distinguishing F1-F2 from F3-F4 with AUC of 0.751 (all P＜0.01). Conclusions: DKI related parameters MD and MK have a good application value in the staging diagnosis of rabbits’ liver fibrosis.]]></description>
<pubDate>Tue,20 Oct 2020 00:00:00  GMT</pubDate>
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<title><![CDATA[Imaging findings of intravascular lymphoma of central nervous system: Report of 4 cases and literature review]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2020.10.013</link>
<description><![CDATA[Objective: To summarize the brain MRI manifestations of intravascular(diffuse large B-cell) lymphoma, improving the understanding of intravascular lymphoma. Materials and Methods: The brain MRI findings of 4 cases of intravascular lymphoma confirmed by skin and brain biopsy were analyzed retrospectively. Combined with the clinical manifestations, laboratory examination, the key features of MRI for diagnosis of intravascular lymphoma were summarized. Results: The clinical manifestations were haemophilus syndrome in 1 case and rapid cognitive decline/progressive dementia in 3 cases. Abnormal brain MRI were displayed in all 4 cases, which showed as multiple lesions with high signal on T2WI, high signal on DWI with slight ADC reduced. The lesions were mainly located in the white matter of bilateral cerebral hemisphere and did not in accordance with the vascular distribution area. In 3 cases, short-term follow-up MRI before biopsy showed that there are always new DWI high signal lesions. Conclusions: When a patient have fever or rapid cognitive decline , and with abnormal brain MR imaging findings, which showed multiple DWI hyperintensity lesions located in brain white matter bilaterally, did not in accordance with the vascular distribution area, with or without ADC reduced, the possibility of intravascular B-cell lymphoma should be highly suspected.]]></description>
<pubDate>Tue,20 Oct 2020 00:00:00  GMT</pubDate>
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<title><![CDATA[MRI-PWI was used to evaluate cerebral blood perfusion and collateral circulation in symptomatic stroke patients]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2020.10.014</link>
<description><![CDATA[Objective: To study the clinical value of MRI perfusion imaging in the evaluation of cerebral ischemia perfusion and collateral circulation in symptomatic stroke patients. Materials and Methods: The total of 80 patients with symptomatic stroke were selected from August 2018 to August 2019. All the patients with negative DWI imaging results underwent conventional MRI, and then underwent MRI-PWI. The reginal cerebral blood volume (rCBV), reginal cerebral blood flow (rCBF), mean transit time (MTT), time to peak (TTP) values and time-density curves of the affected and healthy sides were measured and analyzed. Results: In 29 cases of DWI results can be negative patients, 25 cases of brain exists abnormal perfusion areas, including Ⅰ phase 1 8 cases, 6 patients with Ⅰ phase 2, Ⅱ phase 1 in 5 cases, Ⅱ phase 2 and 6 cases of ischemia area compared with the contralateral, rCBV, rCBF, determined by MTT, TTP differences statistically difference (P＜0.05) in Ⅰ phase 2 and Ⅱ phase 1 establish good collateral vessels. Conclusions: PWI has a higher detection rate in the early hypoperfusion area of brain tissue and can evaluate the status of peripheral microvessels, providing a strong diagnostic basis for patients with early ischemic stroke.]]></description>
<pubDate>Tue,20 Oct 2020 00:00:00  GMT</pubDate>
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<title><![CDATA[MRI characteristics and prognosis in patients with intracranial tumors]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2020.10.015</link>
<description><![CDATA[Objective: To explore the MRI characteristics and prognosis of patients with intracranial tumors. Materials and Methods: A total of 128 patients with intracranial tumors admitted to the First People’s Hospital of Tianmen in Hubei Province from March 2017 to May 2019 were enrolled; meanwhile, 130 healthy people were selected as the control group. The MRI features of the two groups were observed. The patients with intracranial tumors were evaluated for prognostic cognitive function after 12 weeks of treatment, and the correlation between MRI imaging features and cognitive function was analyzed. Results: The scores of the Montreal Cognitive Assessment scale (MoCA) in the observation group were lower than those in the control group (P＜0.05). The MRI leukoaraiosis in level 1-4 in the observation group were 23.4%, 26.6%, 30.5%, 19.5%, respectively; and those in the control group were 88.5%, 10.0%, 1.5%, 0.0%, respectively (P＜0.05). MRI showed that intratumoral vascular emptying accounted for 88.3% (113/128), peritumoral edema accounted for 65.6% (84/128), intratumoral bleeding accounted for 84.4% (108/128), and cystic necrosis accounted for 76.6%(98/128). According to Pearson correlation analysis, the MoCA score was negatively correlated with leukoaraiosis, intratumoral vascular emptying, peritumoral edema, intratumoral hemorrhage, and cystic necrosis (P＜0.05). Conclusions: MRI imaging analysis showed that the imaging features of patients with intracranial tumors were leukoaraiosis, intratumoral vascular emptying, peritumoral edema, intratumoral hemorrhage, cystic necrosis; besides, the more serious the above phenomenon, the worse the cognitive function of prognosis.]]></description>
<pubDate>Tue,20 Oct 2020 00:00:00  GMT</pubDate>
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<title><![CDATA[Prognostic value of cardiac magnetic resonance-late gadolinium enhancement (CMR-LGE) in patients with end-stage hypertrophic cardiomyopathy]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2020.10.016</link>
<description><![CDATA[Objective: To investigate the prognostic value of cardiac magnetic resonance-late gadolinium enhancement (CMR-LGE) in patients with end-stage hypertrophic cardiomyopathy (ES-HCM). Materials and Methods: One hundred and three patients with ES-HCM in our hospital from August 2015 to November 2019 were enrolled, and divided into two groups according to the absence or presence of LGE, LGE-negative group (n=26) and LGE-positive group (n=77). The clinical symptoms and signs, CMR parameters, and the incidence of major adverse cardiovascular events (MACE) were compared between the two groups. Results: The proportion of palpitations, chest tightness, chest pain, dyspnea, lower extremity edema, syncope, cardiac murmur, and arrhythmia in the LGE-positive group had no significant difference with that of the LGE-negative group (P=0.873, 0.570, 0.916, 0.872, 0.805, 0.981, 0.598, 0.975). The left ventricular maximum wall thickness (LVMWT) in the LGE-positive group was significantly higher than that in the LGE-negative group (P=0.000); the left ventricular ejection fraction (LVEF) in the LGE-positive group was significantly lower than that in the LGE-negative group (P=0.000); Left ventricular end-systolic volume (LVESV), right ventricular ejection fraction (RVEF), left ventricular stroke volume (LVSV), left ventricular end-diastolic volume (LVEDV), right ventricular stroke volume (RVSV), right ventricular end-diastolic volume (RVEDV), left ventricular myocardial mass (LVMM), and right ventricular end-systolic volume (RVESV) had no significant difference between groups (P=0.874, 0.869, 0.929, 0.949, 0.853, 0.918, 0.986, 0.818). During the follow-up period, the incidence of MACE in the LGE-positive group was significantly higher than that in the LGE-negative group (P=0.049). Conclusions: CMR-LGE has certain clinical value in the prognosis assessment of end-stage hypertrophic cardiomyopathy.]]></description>
<pubDate>Tue,20 Oct 2020 00:00:00  GMT</pubDate>
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<title><![CDATA[The principle of amide proton transfer imaging and advances in arterial occlusive cerebral infarction]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2020.10.023</link>
<description><![CDATA[Cerebral infarction is the most common cerebrovascular disease, and arterial occlusive infarction is the common type. Decreased blood perfusion in the cerebral arterial blood supply area causes a series of pathophysiological changes, including changes in metabolism and chemical environment. Currently, computed tomography (CT) or MRI structural images, and even some conventional functional imaging, are difficult to show acid-base metabolic changes in cerebral infarction. Amide proton transfer (APT) imaging technique can detect the changes of brain metabolites, evaluate the metabolic changes of brain tissue after infarction, and clarify the chemical environment evolution of ischemic tissue. In this paper, we reviewed the progress in arterial occlusive cerebral infarction with amide proton transfer imaging.]]></description>
<pubDate>Tue,20 Oct 2020 00:00:00  GMT</pubDate>
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<title><![CDATA[Application progress of functional magnetic resonance imaging on differential diagnosis between tumor recurrence and pseudoprogression of gliomas]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2020.10.024</link>
<description><![CDATA[Gliomas are the most common primary malignant brain tumors in adults with a dismal prognosis. The postoperative recurrence and pseudoprogression of gliomas may present with new and/or increasing enhancing mass lesions in conventional MRI. Differential diagnosis of glioma postoperative recurrence and pseudoprogression is still a major clinical challenge because management of these two entities is diametrically opposed. This article reviews the current research on the application of magnetic resonance imaging techniques in the evaluation of postoperative recurrence and pseudoprogression of gliomas.]]></description>
<pubDate>Tue,20 Oct 2020 00:00:00  GMT</pubDate>
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<title><![CDATA[Status of artificial intelligence in meningioma image]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2020.10.025</link>
<description><![CDATA[The usage of artificial intelligence (AI) in medical images is rapid. It has been used in the images of meningioma for the accurate segmentation of peritumoral edema, prediction of pathological grades, and differential diagnosis. This paper is to review the application and further progression of AI in meningioma images.]]></description>
<pubDate>Tue,20 Oct 2020 00:00:00  GMT</pubDate>
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<title><![CDATA[FMRI research progress of post-stroke aphasis following treatment]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2020.10.026</link>
<description><![CDATA[Post-stroke aphasis (PSA) is one of the most common type of aphasia, mainly manifested by sensory, motor and aphasia. Speech rehabilitation therapy is the most important treatment for PSA. It can promote the function of brain remodeling and language function. The mechanism is unclear. Previous studies are mostly limited to the brain morphology investigation, and it is difficult to reveal brain function alteration following PSA treatment. With the advancement of functional magnetic resonance imaging (fMRI) and its post-processing technology, fMRI findings in brain function after PSA treatment may play an important contribution to the study of neural remodeling mechanism following PSA treatment.]]></description>
<pubDate>Tue,20 Oct 2020 00:00:00  GMT</pubDate>
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<title><![CDATA[Application progresses of intravoxel incoherent motion imaging in heart disease]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2020.10.027</link>
<description><![CDATA[Since the emergence of intravoxel incoherent motion (IVIM) technique, after nearly 30 years of continuous development and practice, considerable progress has been made in quantitatively reflecting the diffusion and perfusion information of living tissue. As a new technique reflecting the pathological and physiological characteristics of myocardial tissue at the molecular level, it has clinical significance for the diagnosis and treatment of heart disease, but also faces many challenges. The application progresses of IVIM in heart disease were reviewed in this article.]]></description>
<pubDate>Tue,20 Oct 2020 00:00:00  GMT</pubDate>
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<title><![CDATA[Progress of Gd-EOB-DTPA in the diagnosis and evaluation of HCC]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2020.10.028</link>
<description><![CDATA[gadolinium ethoxybenzyl diethylenetriamine pentaacetic acid (Gd-EOB-DTPA) has become an important tool for the diagnosis of hepatocellular carcinoma. It can improve the sensitivity and accuracy of hepatocellular carcinoma (HCC) and early HCC, and can reflect the biological characteristics and differentiation of HCC lesions, and provide new guidance for pre- and post-treatment evaluation of HCC. This article reviews the research progress of Gd-EOB-DTPA in the diagnosis and biological characteristics evaluation of HCC.]]></description>
<pubDate>Tue,20 Oct 2020 00:00:00  GMT</pubDate>
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<title><![CDATA[Research progress of neoadjuvant radiotherapy and chemotherapy for rectal cancer based on magnetic resonance imaging radiology]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2020.10.029</link>
<description><![CDATA[Neoadjuvant chemoradiotherapy followed by total mesorectal excision is the standard treatment for locally advanced rectal cancer, so it is necessary to evaluate whether patients have a good response before treatment. Quantify MRI and functional imaging have limitations in prediction of response, while radiomics can predict the treatment efficacy by high-dimensional feature extraction. Therefore, this article reviews the methods and current status of quantify MRI andradiomics for predicting the efficacy of neoadjuvant chemoradiotherapy in patients with locally advanced rectal cancer.]]></description>
<pubDate>Tue,20 Oct 2020 00:00:00  GMT</pubDate>
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<title><![CDATA[Research progress of functional magnetic resonance imaging in chronic kidney disease]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2020.10.030</link>
<description><![CDATA[Chronic kidney disease (CKD), characterized by high incidence, poor health outcomes and high treatment costs, imposes a huge burden on individuals and society. Renal tubulointerstitial fibrosis and renal medulla hypoxia are believed to be the main causes of CKD progression. At present, ultrasound-guided renal biopsy is the gold standard for the evaluation and diagnosis of renal fibrosis. However, it is difficult to carry out follow-up monitoring in clinical practice because it is an invasive test with certain side effects and poor repeatability. MRI can provide information about tissue structure noninvasively, and advances in MRI functional imaging techniques offer promise for unique insights into renal function and fibrosis severity, but its potential to assess fibrosis and inflammation in diseased kidneys remains unclear. This paper reviews the research progress of functional magnetic resonance imagingin the diagnosis of chronic kidney disease.]]></description>
<pubDate>Tue,20 Oct 2020 00:00:00  GMT</pubDate>
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<title><![CDATA[The application of <sup>19</sup>F-MR molecular imaging in targeted drug delivery]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2020.10.031</link>
<description><![CDATA[In recent years,  <sup>19</sup>F magnetic resonance ( <sup>19</sup>F-MR) molecular imaging represents a compelling option for studying targeted drug delivery. Due to the lack of endogenous fluorine in living organisms and the excellent sensitivity of  <sup>19</sup>F, nanomaterials including liquid perfluorocarbon (PFC) have been developed as ideal molecular imaging probes for  <sup>19</sup>F-MR imaging. The combination of  <sup>19</sup>F-MR imaging and targeted drug delivery presents an ideal modality for tumor-targeted theranostic, which improves the chances of diagnosis, therapy, efficacy monitoring and prognosis evaluation. In this review, we present our perspective on  <sup>19</sup>F-MR molecular imaging developments for the investigation of targeted drug delivery and stimuli-responsive drug release. And their application and the advantages and disadvantages are discussed, in order to provide theoretical basis and data support for the design, preparation, development and application of new multifunctional nanomaterials that can be used for  <sup>19</sup>F-MR molecular imaging.]]></description>
<pubDate>Tue,20 Oct 2020 00:00:00  GMT</pubDate>
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<title><![CDATA[Advances in clinical research of radiomics in bone tumors]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2020.10.032</link>
<description><![CDATA[With the development of artificial intelligence technology and the concept of precision medicine, the traditional imaging diagnosis model is gradually difficult to meet the needs of personalized medical activities. Radiomics, which uses high-throughput quantitative feature extraction methods to convert images into minable data and analyzes the data using machine learning algorithms to provide clinical decision support, has received widespread attention. Many existing studies have tried to apply radiomics to the clinical diagnosis and treatment of bone tumors. This article will focus on a brief overview of radiomics techniques from an application perspective, detailing the progress of radiomics studies in diagnosis and differential diagnosis, typing and stage, prognosis prediction and genetic analysis of bone tumor, and presenting the current challenges and future development direction.]]></description>
<pubDate>Tue,20 Oct 2020 00:00:00  GMT</pubDate>
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