http://med-sci.cn/cgzcx/en/contents_list.asp?issue=202210 zh-cn An RSS feed for Chinese Journal of Magnetic Resonance Imaging http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2022.10.001 Thu,20 Oct 2022 00:00:00 GMT http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2022.10.002 Thu,20 Oct 2022 00:00:00 GMT http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2022.10.003 ^,s health awareness, the help of the Musculoskeletal Group of Chinese Society of Radiology the development of professional courses and lectures, and the continuous emergence of scientific research results, musculoskeletal imaging has received more and more attention. The influence of the discipline is continuously improved, and the professional ability of radiologists is continually improved. With the update of MRI hardware facilities, the development of accessories, and the development and application of related technologies, the clinical value and application scope of musculoskeletal imaging have continued to increase, benefiting more and more patients. Musculoskeletal imaging plays an irreplaceable role in the identification, diagnosis, differential diagnosis and quantitative analysis of various musculoskeletal diseases. It provides valuable information for clinical diagnosis and treatment, assists clinical decision-making, and is an indispensable inspection method for accurate medical treatment. Nevertheless, musculoskeletal imaging still has great potential for improvement in many aspects, such as postoperative efficacy evaluation, artificial intelligence (AI)-aided diagnosis, early disease screening, etc. The past ten years have been an important stage in the development of musculoskeletal imaging. The increase in the penetration rate of MRI equipment, the development of different diagnostic techniques, and the emergence of AI-enabled intelligent medical care have all provided opportunities for the development of musculoskeletal imaging. It is believed that shortly, musculoskeletal imaging will be able to break new ground, forge ahead, continue to improve and make more outstanding contributions to the national health strategy and the people^,s health.]]> Thu,20 Oct 2022 00:00:00 GMT http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2022.10.004 Thu,20 Oct 2022 00:00:00 GMT http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2022.10.005 Thu,20 Oct 2022 00:00:00 GMT http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2022.10.006 Thu,20 Oct 2022 00:00:00 GMT http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2022.10.007 ^,s neuroradiologists have been promoting the diagnosis, treatment, prevention, and scientific research of cerebrovascular diseases towards a more precise and scientific direction. Further research on cerebrovascular imaging based on clinical scientific issues will further enhance China radiology^,s influence in the world.]]> Thu,20 Oct 2022 00:00:00 GMT http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2022.10.008 Thu,20 Oct 2022 00:00:00 GMT http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2022.10.009 Thu,20 Oct 2022 00:00:00 GMT http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2022.10.010 Thu,20 Oct 2022 00:00:00 GMT http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2022.10.011 P＜0.05), the risperidone-treated group showed decreased FA values of 17 fiber tracts (P＜0.05) except left uncinate tracts and double arcuate tracts (P＞0.05), while MD values had no significant difference (P＞0.05). Compared with the never-treated group, the risperidone-treated group showed significantly increased FA values of the other 18 fasciculus (P＜0.05) except the left arcuate fasciculus and right superior longitudinal fasciculus (P＞0.05), and decreased MD values involving bilateral corticospinal tract, bilateral cingulate cingulate pathway, bilateral inferior fronto-occipital tract, left anterior thalamic radiation, left cingulate cingulate pathway, left inferior longitudinal tract, left superior longitudinal tract, right uncinate tract, the splenium and the genu of the corpus callosum (P＜0.05). There were no significant differences in FA and MD between the clozapine-treated group and never-treated group (P＞0.05). Compared with the clozapine-treated group, the risperidone-treated group showed significantly increased FA values involving bilateral anterior thalamic radiation, bilateral inferior fronto-occipital fasciculus, bilateral inferior longitudinal fasciculus, left corticospinal tract, left uncinate fasciculus, right arcuate fasciculus, right cingulum-hippocampus pathway, the splenium and the genu of the corpus callosum, and significantly decreased MD values involving bilateral inferior frontal-occipital tract, bilateral uncinate fasciculus, left inferior longitudinal fasciculus and right cingulum-hippocampus pathway (P＜0.05). The severity of symptoms in the patients with chronic schizophrenia was negatively correlated with the FA value and positively correlated with the MD value (P＜0.05).ConclusionsPatients with chronic schizophrenia with clozapine monotherapy showed more severe and extensive white matter microstructure defects than patients with risperidone monotherapy, suggesting that different antipsychotics had different effects in white matter characteristics.]]> Thu,20 Oct 2022 00:00:00 GMT http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2022.10.012 P＜0.05). The node efficiency of frontal lobe, anterior cingulate gyrus, thalamus and other brain regions increased (P＜0.05), the betweenness centrality of right anterior central gyrus, left wedge lobe and left posterior central gyrus decreased (P＜0.05), but the betweenness centrality of left superior frontal gyrus and left inferior frontal gyrus increased (P＜0.05). There was a negative correlation between the betweenness centrality of the left inferior frontal gyrus pars operculariscan and the ALSFAR-R score (r=-0.514, P=0.012).ConclusionsThe abnormal changes of the structure network of motor brain and extramotor brain in ALS patients may provide imaging basis for the diagnosis and prognosis evaluation of brain injury.]]> Thu,20 Oct 2022 00:00:00 GMT http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2022.10.013 plaque≤ER_{reference vessel wall}), grade 1 (ER_{reference vessel wall}＜ER_plaque＜ER_{pituitary infundibulum}) and grade 2 (ER_plaque≥ER_{pituitary infundibulum}). Differences of clinical and plaque characteristics between groups were compared using t-test, Mann-Whitney U test, or chi-square test. Correlations between plaque characteristics and ABCD3 scores were analyzed by Spearman rank correlation or Pearson correlation.ResultsSeventy-two patients underwent HR-MRI with TIA were retrospectively analyzed, the NWI and RI in the high-risk group (n=39, 54.17%) were significantly higher than those in the low-to-intermediate-risk group (n=33, 45.83%) [0.86 (0.76, 0.92) vs. 0.62 (0.49, 0.75); 1.25 (1.05, 1.33) vs. 1.00 (0.81, 1.11); P＜0.05]. The proportion of intraplaque hemorrhage (IPH) and grade 2 enhancement was significantly higher in the high-risk group than in the low-to-intermediate-risk group [74.4% vs. 33.3%; 56.4% vs. 6.1%; P＜0.05]. The NWI (r=0.661, P＜0.01), IPH (r=0.388, P＜0.01), and plaque enhancement (r=0.467, P＜0.01) were positively correlated with the ABCD3 score.ConclusionsThis study revealed different morphological characteristics of intracranial atherosclerotic plaques in patients with low-to-medium-risk and high-risk TIA. NWI, IPH and grade 2 enhancement are potential indicators to identify high-risk TIA patients. Probing these features with HR-MRI may provide insights into the early intervention of patients with TIA.]]> Thu,20 Oct 2022 00:00:00 GMT http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2022.10.014 t-test or Mann-Whitney U test was used to compare measurement data between the two groups, and Fisher^,s exact test was used to compare categorical data. A comprehensive model was established by screening histogram parameters with difference through logistic regression analysis. By drawing receiver operating characteristic (ROC) curve and calculating area under the curve (AUC), the differential diagnosis efficiencies of each parameter and the comprehensive model were evaluated.ResultsIn ADC, skewness and Pere.01%, Pere.10% had statistically significant differences (P＜0.05), and AUC were 0.701, 0.778 and 0.642, respectively. In CE-T1WI, variance is statistically significant (P＜0.05), and AUC was 0.743. The comprehensive model established by logistic regression analysis showed AUC of 0.854, sensitivity of 68.8% and specificity of 88.9%.ConclusionsThe quantitative parameters obtained based on ADC and CE-T1WI histogram analysis of tumor maximum layer have certain value in preoperative differential diagnosis of AT/RT and MB, and provide a reference for the selection of clinical treatment.]]> Thu,20 Oct 2022 00:00:00 GMT http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2022.10.015 CI: 4.72-4.80)] mm. Upon simple linear regression analysis, we observed that the mean ONSD did vary with sex (P=0.002) and ETD (P=0.002). Further multiple linear regression analysis also showed that sex (P＜0.001) and ETD (P=0.001) were associated with ONSD. The mean ONSD for males was (4.86±0.42) mm compared with (4.63±0.40) mm for females, which meant a significant difference between the two groups (P＜0.001). We further assessed a normative value for the ONSD/ETD ratio, the mean value of which was 0.22 (95% CI: 0.21-0.22) mm.ConclusionsThis study established the range of MRI-based ONSD in healthy Chinese adults. Sex and ETD were the influencing factors of ONSD measurement. The difference in the ONSD value by sex suggest that separate normal reference ranges are need for men and women.]]> Thu,20 Oct 2022 00:00:00 GMT http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2022.10.016 Thu,20 Oct 2022 00:00:00 GMT http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2022.10.017 P＜0.05). The general subjective IQ scores of cine-MoCo and cine-SegBH were (4.4±0.7) and (4.1±0.8), respectively (P＜0.05), and the standardized criteria IQ scores of cine-MoCo and cine-SegBH based on the European CMR registry standardized criteria were (0.125±0.404) and (0.425±0.844), respectively (P＜0.05). There was no significant difference by edge sharpness measurement between cine-SegBH and cine-MoCo [(0.064±0.133) vs. (0.065±0.139), P＞0.05]. There were no significant differences in the assessment of RV functional parameters between cine-SegBH and cine-MoCo, including RV ejection fraction (RVEF), RV end-diastolic volume (RVEDV), RV end-systolic volume (RVESV), RV stroke volumes (RVSV), and RV mass (RVM), additionally, all RV functional parameters showed strong correlations (r=0.966-0.992) between the two cine techniques. RV myocardial strain including global longitudinal strain (GLS), global circumferential strain (GCS), and global radial strain (GRS) derived from cine-MoCo were significantly lower than those by cine-SegBH (all P＜0.05). GCS and GRS showed strong correlations (r=0.895 for GCS; r=0.908 for GRS), but GLS showed a weak correlation (r=0.564) between the two cine techniques. Subgroup analysis showed that GLS, GCS, and GRS measured with cine-MoCo were significantly underestimated in patients with mild PAH (WHO function class Ⅰ-Ⅱ, Group 1) but no significant differences in patients with severe PAH (WHO function class Ⅲ-Ⅳ, Group 2) when compared with those measured with cine-SegBH. All parameters for both techniques showed good intra-observer and inter-observer agreement.ConclusionsCompared with cine-SegBH, cine-MoCo can shorten image acquisition time, obtain equivalent or even better IQ, and achieve precise quantitative analytic results for RV function in patients with PAH, and obtain accurate strain evaluation in patients with severe PAH.]]> Thu,20 Oct 2022 00:00:00 GMT http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2022.10.018 18F-fluorodeoxyglucose-positron emission tomography (¹⁸F-FDG PET) in assessing the proliferation status of lung adenocarcinoma.Materials and MethodsA total of 64 patients with lung adenocarcinoma confirmed by pathology in our hospital were included. The expression of Ki-67 in lung cancer tissues was detected by immunohistochemistry and divided into the high Ki-67 group (＞25%) and the low Ki-67 group (≤25%). Before treatment, all patients underwent a dedicated thoracic ¹⁸F-FDG PET/MR examination. The DWI was scanned with 10 b-values (0-1000 s/mm²). The apparent diffusion coefficient (ADC), a microstructural quantity (μ), diffusion coefficient (D), fractional order parameter (β) and maximum standardized uptake value (SUV_max) were compared between the two groups. The independent predictors of Ki-67 proliferative status were analyzed by multivariate logistic regression, receiver operating characteristic (ROC) curve was used to evaluate the discriminant performance, and the correlation between each parameter and Ki-67 was analyzed.ResultsThe ADC, D, and β values in the low Ki-67 group were significantly higher than in the high Ki-67 group (P＜0.05), and the μ and SUV_max values in the high Ki-67 group were significantly higher than in the low Ki-67 group (P＜0.05). The area under the curve (AUC) of parameters D and SUV_max were 0.873 and 0.727, respectively, and multivariate logistic regression showed that parameters D (OR: 0.421, 95% CI: 0.245-0.723, P=0.002) and SUV_max (OR: 1.022, 95% CI: 1.002-1.042, P=0.031) were independent risk factors for high Ki-67 expression. ADC and D values were negatively correlated with Ki-67 (r=-0.361, r=-0.420), and μ and SUV_max values were positively correlated with Ki-67 (r=0.369, r=0.527).ConclusionsMonoexponential, FROC models and ¹⁸F-FDG PET are effective methods to evaluate the proliferation status of lung adenocarcinoma, and the D value of FROC model shows the highest diagnostic performance. FROC model provides a new perspective for exploring the information of tumor tissue microenvironment, and has great potential in non-invasive evaluation of lung adenocarcinoma proliferation, and its clinical application has broad prospects.]]> Thu,20 Oct 2022 00:00:00 GMT http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2022.10.019 t-test or Mann-Whitney U test were used to compare the clinical data and imaging parameters of the two groups; and Spearman correlation analysis was performed on the average blood flow velocity in early diastole, left ventricular myocardial mass, and peak diastolic thickness of the left ventricular wall.ResultsThe left ventricular mass (LV_mass) and the global peak wall thickness (GPWT) in the HCM group were significantly higher than those in the healthy control group [LV_mass: (163.70±52.18) vs. (87.27±21.01), unit: g; GPWT: (19.64±3.85) vs. (9.99±2.00), unit: mm; HCM group vs. healthy control group, P＜0.001]; for the average diastolic blood flow velocity at the level of the mitral valve, the average blood flow velocity in the early diastole of the HCM group was lower than that of the healthy control group [29.70 (17.90) vs. 50.50 (16.90), unit: cm/s; HCM group vs. healthy control group, P＜0.001]; the mean blood flow velocity in late diastole between HCM patients and the control group was not statistically different; the E/A value of the HCM group was significantly lower than that of the healthy control group [(1.26±0.70) vs. (1.80±0.85), HCM group vs. healthy control group, P=0.003].ConclusionsThe use of CMR 4D Flow can visualize the blood flow in the left ventricle, accurately distinguish the intraventricular blood flow trajectory of the heart in the early and late diastole. In addition, the decrease of mean flow velocity in the early diastolic stage of mitral valve level (E peak) and E/A value is helpful for quantitative evaluation of left ventricular diastolic dysfunction in patients with hypertrophic cardiomyopathy, and provides a reference for patients to formulate individualized treatment plans.]]> Thu,20 Oct 2022 00:00:00 GMT http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2022.10.020 n=250) and validation groups (n=62) according to the ratio of 8∶2. Firstly, doctors adopted 3D Slicer software to extract 3D imaging radiomics features from the 5 mm region in and around stage 2 of DCE-MRI images. Secondly, features were standardized with Z-score, and intra-class correlation coefficient (ICC), Spearman correlation coefficient and least absolute shrinkage and selection operator (LASSO) were used to screen the optimal radiomics features. Thirdly, model_intra, model_peri, model_intra+peri were established by support vector machine (SVM) algorithms to predict the expression status of Ki-67 in breast cancer and were verified by the validation groups. Fourthly, the performance models were assessed by the receiver operating characteristic (ROC) curve and area under the curve (AUC).ResultsThe features of intratumor, peritumor, intratumor+peritumor were extracted 1906, 1906 and 3812 samples respectively, 322, 413 and 762 features were excluded by ICC, and 624, 732 and 1604 were eliminated by Spearman, after that 8, 19 and 16 features were selected by LASSO from the rest of 960, 761 and 1446 features. With comprehensive analysis, the model_intra+peri showed the best prognostic efficacy, with AUC of 0.949 and 0.862 in the training and validation groups respectively. The calibration curve nearly showed the best value of 45%, Hosmer-Lemeshow goodness-of-fit test suggested that the curve of the model fitted the data with high efficiency (P=0.082), decision curve analysis showed better results than other models and benefits in the clinic application.ConclusionsThe predicting model of Ki-67 was creatively established by DCE-MRI and intratumoral combined peritumoral 3D radiomics model, the research provides accurate personal treatment in the breast cancer.]]> Thu,20 Oct 2022 00:00:00 GMT http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2022.10.021 ^,s Kappa was used to analyze intra‐reader agreement.ResultsThree‐plane PDWI accelerated with, PI, CS, ACS were acquired in 428 s, 375 s and 155 s, respectively. The subjective scores of the three-plane images were not different among the three groups (P=0.607, 0.174, 0.529, respectively). The agreement grading cartilage abnormalities in 14 regions of CS-PI, ACS‐PI were excellent (ICC ranging 0.969-0.995 and 0.951-0.987, respectively). Removing the regions with negative diagnosis in the three groups, the agreement in grading cartilage abnormalities of CS-PI, ACS-PI were still excellent (ICC ranging 0.868-0.939 and 0.842-0.948, respectively). The specificity of CS and ACS was 99.6% and 98.2%, respectively. The range of sensitivity of CS and ACS in grade 1-6 was 42.3%-100.0% and 17.3%-87.9%, respectively. Grading cartilage abnormalities showed perfect agreement (κ≥0.803) in 3 regions of 15 subjects for PI, CS and ACS.ConclusionsACS greatly accelerates multi‐plane MRI PDWI sequences while ensuring image quality, and achieve comparable diagnostic performance with sequences accelerated with parallel imaging in semi‐quantitative evaluation of multi‐region cartilage injury in knee osteoarthritis.]]> Thu,20 Oct 2022 00:00:00 GMT http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2022.10.022 P＜0.016) for post hoc two-by-two comparisons of FC values. Finally, Pearson correlation analysis was performed between FC values and clinical scale scores for the statistically different brain regions among the 3 groups.Results(1) Compared with the FDE group, the FC of the left amygdala with the left and right anterior cingulate gyrus/left orbital part of the superior frontal gyrus was increased in the RDE group, and the FC of the right amygdala with the right precentral gyrus/right precuneus and right supplementary motor area/right middle cingulate gyrus was increased in the RDE group. Compared with the HC group, the FC of the left amygdala with the left and right anterior cingulate gyrus/left orbital part of the superior frontal gyrus was increased in the RDE group. (2) The FC values of the left amygdala and the left and right anterior cingulate/left orbital part of the superior frontal gyrus in the RDE group were positively correlated with the Rumination Response Scale (RRS) scores (r=0.460, P=0.033).ConclusionsThere were differences in FC between RDE and FDE in the amygdala and limbic circuits, reward circuit, somatosensory-motor areas and default mode network, and a more extensive FC alteration feature was present in RDE, which may be the reason why the neuropathological mechanism of RDE is more complex.]]> Thu,20 Oct 2022 00:00:00 GMT http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2022.10.023 ⊥) imaging. The corpus callosum and external capsule regions were outlined to calculate the SIR value, FA value, ADC value, and D_⊥ value, and a one-way analysis of variance was performed among the three groups. At the end of scanning, the samples were obtained for luxol fast blue (LFB) -tar purple pathological staining, and the mean grayscale value (MGSV) was measured. One-way analysis of variance between the three groups was performed. Pairwise correlation analysis was performed between the statistically significant imaging data and the MGSV.ResultsCompared with group A, group B had decreased SIR (P=0.044), fractional anisotropy (FA; P=0.001), apparent diffusion coefficient (ADC; P=0.001) and radial diffusion coefficient (D_⊥; P=0.001) values in the external capsule region. Group C had decreased SIR (P＜0.001) and FA (P=0.002) in the external capsule region. SIR (P=0.031) and FA (P=0.015) in the corpus callosum were decreased. LFB-tar purple poorly stained the areas of the myelin sheath that were damaged due to stroke, and the mean grayscale value (MGSV) decreased (P＜0.05). In the external capsule region, MGSV was negatively correlated with SIR (P＜0.0001), FA (P≤0.0001), ADC (P=0.0127), and D_⊥ (P=0.0180). In the corpus callosum region, MGSV was negatively correlated with SIR (P=0.0018).ConclusionsA combination of SIR and DTI can be used as a noninvasive imaging method to evaluate the different stages of myelin injury in ischemic stroke. This has been proven effective in rat models and provides a helpful imaging basis for clinical diagnosis and treatment.]]> Thu,20 Oct 2022 00:00:00 GMT http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2022.10.024 ω1, the exchange rate kex and the CEST signal was established based on the Bloch-McConnell equation, so as to pass the CEST under different B1. Signals were exchanged for rate quantification. According to this method, the CEST images were calculated pixel by pixel to obtain the corresponding exchange rate imaging. The independent sample t-test was used to compare the exchange rates of detected lesions and normal tissues between groups, and the contrast-to-noise ratio (CNR) was used to compare the exchange rates between groups. The CNR metric to quantify the contrast between exchange rate imaging and raw CEST imaging.ResultsRelative to the contralateral normal tissue, exchange rate imaging showed markedly low signal in the lesion area. Compared with transverse relaxation-weighted imaging (T2W) and diffusion-weighted imaging (DWI), for the short term after reperfusion, exchange rate imaging showed stronger contrast in the lesion area. The kex value in the lesion area detected by exchange rate imaging was statistically significant compared with the rest of the normal tissues (P＜0.01). With a total of 6 groups of rat comparison experiments, all the exchange rate images showed higher CNR values compared to the original CEST images.ConclusionsProton exchange rate imaging can detect acidic lesions in tissues after ischemic stroke, and has potential as an endogenous quantitative imaging biomarker.]]> Thu,20 Oct 2022 00:00:00 GMT http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2022.10.025 U test. The SNR and FDi of glioma peripheral areas in the two groups were analyzed by paired t-test (when P＜0.05, it was considered statistically significant).ResultsThe image quality score of MUSE DTI and SS-EPI DTI were 4 (4, 5), 3 (2, 3) [M (P25, P75), Z=0.87, P＜0.01]. The SNR of the peritumoral area was 65.43±32.91 and 23.41±21.21 (P＜0.01). The FDi values were 0.83±0.87, 0.68±0.71 (P＜0.05). The comprehensive quality scores of the two groups of images, SNR and FDi values of the surrounding areas of the tumor had statistically differences.ConclusionsMUSE DTI can enhance the image quality of the area around glioma, improve the visualization accuracy of white matter fiber bundles around the tumor, and provide accurate imaging evidence for clinical diagnosis and treatment.]]> Thu,20 Oct 2022 00:00:00 GMT