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<title>Chinese Journal of Magnetic Resonance Imaging RSS feed</title>
<link>http://med-sci.cn/cgzcx/en/contents_list.asp?issue=202011</link>
<language>zh-cn</language>
<copyright>An RSS feed for Chinese Journal of Magnetic Resonance Imaging</copyright>
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<title><![CDATA[Degree centrality of brain network in heroin addicts treated with methadone maintenance: a resting-state functional magnetic resonance imaging study]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2020.11.001</link>
<description><![CDATA[Objective: To explore the effect of methadone maintenance treatment on the core nodes of the brain network of heroin addicts. Materials and Methods: Twenty-six heroin addicts during short-term abstinence (HA), 25 heroin addicts during methadone maintenance treatment (MMT) and 42 health controls (HC) were recruited. The resting-state fMRI data of all subjects were collected. Based on the theory of graph theory, the degree centrality (DC) of whole brains of the three groups were compared. The correlations between the DC values and history of heroin addiction and MMT were also analyzed. Results: The DC value of left medial frontal cortex and bilateral inferior parietal lobules in MMT and HC group was significantly lower than that in HA group. The DC value of left anterior precuneus lobe in MMT group was significantly higher than that in HC group. It was found that the DC value of left orbital frontal gyrus and left middle frontal gyrus in HA group and MMT group was significantly higher than that in HC group. The right insular lobe in MMT group was significantly lower than that in HC group and HA group (P＜0.001, P＜0.05 after Alphasim correction, voxels＞25). Conclusions: The methadone maintenance treatment is beneficial to the recovery of self-awareness, self-monitoring of heroin addicts. However, there are still some abnormalities such as salience, decision-making and inhibitory control, which may take longer or other comprehensive interventions to recover.]]></description>
<pubDate>Fri,20 Nov 2020 00:00:00  GMT</pubDate>
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<title><![CDATA[Amplitude of low-frequency fluctuations of resting-state functional MRI in multiple system atrophy patients with depression]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2020.11.002</link>
<description><![CDATA[Objective: To investigate the changes of resting-state spontaneous brain activity in multiple system atrophy patients with depression. Materials and Methods: Thirty-two MSA patients with depression symptom, twenty-six patients without depression and thirty-nine health controls were enrolled. All the participants underwent 3.0 T MRI resting-state blood oxygen level dependence sequence scan. Two sample t-test was used to compare the differences of the whole brain amplitude of low-frequency fluctuations (ALFF) among the three groups, and the correlation between the different brain areas and Hamilton depression score was analyzed. Results: Compared with the HC groups, MSA-D (MSA patients with depressive symptoms) shows more widely brain areas dysfunction which included right inferior temporal gyrus, bilateral putamen, right superior frontal gyrus, left middle frontal gyrus, bilateral middle occipital gyrus, left precuneus and left middle cingulate cortex than MSA-ND (MSA- no depressive symptoms). A directly comparison of the two patient groups, MSA-D shows increase ALFF in right middle temporal gyrus and right middle occipital gyrus. There was a positive correlation between the ALFF value of right middle temporal gyrus and clinical HAMD-24 score (r=-0.511, P=0.003). Conclusions: There is a wide range of resting state brain activity in MSA patients with depressive symptoms, and increased ALFF activity in the right middle temporal gyrus may be a potential biomarker for depressive symptoms in MSA.]]></description>
<pubDate>Fri,20 Nov 2020 00:00:00  GMT</pubDate>
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<title><![CDATA[The study on the correlation between hypoperfusion intensity ratio and angiography collateral circulation in acute ischemic stroke before endovascular thrombectomy therapy]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2020.11.003</link>
<description><![CDATA[Objective: To investigate the correlation between hypoperfusion intensity ratio (HIR) and collateral circulation using digital subtraction angiography (DSA) in acute ischemic stroke. Materials and Methods: A total of 100 acute ischemic stroke patients receiving endovascular thrombectomy therapy in our study from January 2017 to March 2020 were analyzed retrospectively. All patients underwent MRI examination [diffusion weighted imaging (DWI)], perfusion weighted imaging (PWI)) before therapy. American Society of Interventional and Therapeutic Neuroradiology (ASITN) grading system was used to evaluate the collateral circulation. ASITN 0—2 grade was poor collateral circulation and ASITN 3—4 was good collateral circulation. HIR was defined as the ratio of the time-to-maximum (Tmax)＞10 s over Tmax＞6 s lesion volumes. The difference was statistically significant (t=9.547, P=0.007; t=7.596, P＜0.001; t=7.118, P=0.016; t=-5.753, P＜0.001). Spearman rank correlation and ROC analysis were performed to evaluate the correlation between HIR and collateral circulation. Results: The Tmax＞6 s (91.62±12.40 vs 125.73±17.91), Tmax＞10 s (26.14±17.74 vs 58.23±29.96), PWI-DWI mismatch volume (72.52±10.08 vs 89.63±14.60) and HIR value (0.33±0.08 vs 0.43±0.09) in good collaterals group (ASITN 3—4) (n=51) was significantly lower than those in poor collaterals group (ASITN 0—2) (n=49). Spearman rank correlation analysis showed that there was a negative correlation between HIR and ASITN (r=-0.672; P＜0.001). ROC analysis showed that the area under the curve of HIR predicting acute stroke collateral circulation was 0.801 (95% CI: 0.714—0.888). When the optimal cut-off value of HIR was 0.40, the sensitivity and specificity for predicting collateral circulation was 77.60% and 74.51% respectively. Conclusions: There is a close relationship between the low HIR and good collateral circulation in patients with acute ischemic stroke before endovascular thrombectomy therapy. Compared with gold standard DSA, HIR is a reliable measurement index of collateral circulation, and HIR＜0.4 is the best predicted good DSA collaterals.]]></description>
<pubDate>Fri,20 Nov 2020 00:00:00  GMT</pubDate>
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<title><![CDATA[Evaluation of glioma benign and malignant based on dynamic contrast-enhanced MR texture analysis of different regions of interest]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2020.11.004</link>
<description><![CDATA[Objective: This study was designed to investigate the role of texture analysis and dynamic contrast-enhanced MR based on different regions of interest (ROI) in determining glioma grade. Materials and Methods: Forty cases of high-grade glioma (grade Ⅲ and Ⅳ WHO) and low-grade glioma (grade Ⅰ and Ⅱ WHO) confirmed by pathology were collected. All patients underwent routine MRI and dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI). ROI is determined by the following two areas: (1) the whole tumor area; (2) the solid part of the tumor. Texture features between high-grade glioma (HGG) and low-grade glioma (LGG) were compared by nonparametric Wilcoxon rank sum test. Results: For the whole tumor ROI, the value of inhomogeneity between HGG and LGG was significantly different (Z=50.37, P=0.01＜0.05). For the real part of ROI, the inhomogeneity showed that the difference between HGG and LGG was not statistically significant (Z=34.65, P=0.06＞0.05). The whole tumor inhomogeneity parameter performed with better diagnostic accuracy. Conclusions: Texture analysis of DCE-MRI based on different ROI can provide reliable value for evaluating glioma grade.]]></description>
<pubDate>Fri,20 Nov 2020 00:00:00  GMT</pubDate>
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<title><![CDATA[A preliminary study on the central analgesic mechanism of acupuncturing the stomach meridian foot-Yangming by fMRI]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2020.11.005</link>
<description><![CDATA[Objective: To explore the central analgesic mechanism of acupuncture of the stomach meridian of foot-Yangming by comparing and analysing the changes of brain functional imaging after pain stimulation and acupuncture point analgesia. Materials and Methods: Twenty healthy volunteers were given pain stimulation and acupuncture at Zusanli and Shangjuxu points in stomach meridian of foot-Yangming respectively. The actived and inhibited area in the brain was recorded by fMRI and analyzed. Results: After pain stimulation and compatibility of acupuncture at two points, the frontal and temporal cortex, the limbic system, the thalamus ,the cerebellum and so on are activated and inhibited in varying degrees and ranges in brain functional imaging, and the difference is statistically significant (k＞30, t＞3.09, P＜0.001). Conclusions: These brain areas reflected by brain functional imaging may participate in pain and the central analgesic mechanism of stomach meridian of foot-Yangming through different regulation ways. And there are both similarities and differences between the central analgesic mechanism of stomach meridian of foot-Yangming and single acupuncture point.]]></description>
<pubDate>Fri,20 Nov 2020 00:00:00  GMT</pubDate>
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<title><![CDATA[The study of functional outcome difference and risk factors between intracranial anterior and posterior circulation in acute stroke patients]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2020.11.006</link>
<description><![CDATA[Objective: To explore the functional outcome difference and risk factors between intracranial anterior and posterior circulation in acute stroke patients. Materials and Methods: Two hundred and ten acute anterior stroke patients and 85 acute posterior stroke patients in our hospital were retrospectively enrolled. All patients≤24 hours of symptom onset and underwent MRI examination before therapy. Patients were divided into intravenous thrombolysis group and arterial thrombectomy group. The clinical data, diffusion-weighted imaging (DWI) infarct volume, vascular recanalization (mTICI score) and the functional outcome at 3 months (mRS) were collected. Statistical analysis was performed to compare the functional outcome difference and risk factors between intracranial anterior and posterior circulation in acute stroke patients. Results: Of the 200 patients underwent intravenous thrombolysis, DWI infarct volume in the anterior circulation group (n=150) was significantly larger than that in posterior circulation group (n=50) (28.04±21.72 vs 13.54±15.17; t= -4.077, P=0.023); while the proportion of good functional outcome in the anterior circulation group was significantly higher than that in posterior circulation group (72.67% vs 42.00%; χ2= 15.502, P=0.000). Of the 95 patients underwent arterial thrombectomy, DWI infarct volume in the anterior circulation group (n=50) was significantly larger than that in posterior circulation group (n=35) (68.04±17.39 vs 43.54±6.17; t=-2.170, P=0.037), the vascular recanalization rate was significantly higher than that in posterior circulation group (mTICI score 2b—3: 78.33% vs 51.43%; χ2 =7.406, P=0.011). Compared with the posterior circulation group, the functional outcome in the anterior circulation group was better (70.00% vs 45.71%); χ2= 5.483; P=0.029). Logistic regression analysis showed that DWI infarct volume [OR (95% CI): 1.34 (1.17—1.54); P=0.021] was independent predictor factors of functional outcome in acute stroke patients underwent intravenous thrombolysis. DWI infarct volume [OR (95% CI):1.19 (1.07—2.85); P=0.034], mTICI score [OR (95% CI): 3.88 (1.27—11.78); P=0.016] were independent predictor factors of functional outcome in acute stroke patients underwent arterial thrombectomy. Conclusions: The functional outcome of acute anterior stroke patients is better than that of acute posterior stroke patients. Evaluating DWI volume and vascular recanalization comprehensively may be useful in predicting the functional outcome of acute stroke patients.]]></description>
<pubDate>Fri,20 Nov 2020 00:00:00  GMT</pubDate>
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<title><![CDATA[Magnetic resonance imaging on morphological abnormalities of brain in 1—3 years old children with autism spectrum disorder]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2020.11.007</link>
<description><![CDATA[Objective: To analyze morphological abnormalities of brain in 1—3 years old children with autism spectrum disorder (ASD) based on voxel-based morphometry (VBM), and to explore the feasibility of early diagnosis of ASD by magnetic resonance imaging (MRI) preliminarily. Materials and Methods: One to three years old children diagnosed first with ASD and age and gender matched normal children were scanned by MRI with high resolution 3D T1WI. Based on the statistical parameter graph (SPM12) with toolkit CAT12 of matlab2012b, VBM was used to analyze 3D T1WI images and the volume of each brain regions were calculated. The two sample t test was used to analyze differences of the volume of the whole brain and each brain regions. Results: There were eligible 17 cases in ASD group [All were male, with an average age of (28.9±9.5) months ranging from 12 to 34 months] and 12 cases in control group [All were male, with an average age of (28.6±10.5) months ranging from 13 to 35 months]. Compared with the control, the gray matter volume and cerebral cortex thickness of the ASD group were larger, and the cerebrospinal fluid volume was smaller (P＜0.05).The volume of gray matter in left posterior central gyrus, right inferior parietal gyrus and left inferior frontal gyrus were showed increased in 1—3 years old children with ASD (P＜0.001, Nuclear group＞100 voxels). Conclusions: There are certain characteristics of morphological abnormalities of brain in 1—3 years old children with ASD. MRI is expected to be a method of early diagnosis of ASD.]]></description>
<pubDate>Fri,20 Nov 2020 00:00:00  GMT</pubDate>
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<title><![CDATA[DWI and 3D SWAN improve the knowledge of pathophysiological mechanism of neonatal bilirubin encephalopathy]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2020.11.008</link>
<description><![CDATA[Objective: To investigate the possible pathophysiological mechanism of hyperbilirubinemia (HB) on neonatal brain tissue injury by analyzing the diffusion-weighted imaging (DWI) and susceptibility weighted imaging (SWI) manifestations of bilirubin encephalopathy in full-term neonates. Materials and Methods: The DWI and (three dimensions T2* weighted angiography (3D SWAN) data of 75 neonates with HB clinically confirmed were analyzed retrospectively. Children with HB were divided into two groups according to the T1WI signal of globus pallidus: normal signal (HBn group, 46 cases) and high-intensity signal group (HBh group, 29 cases). While 44 cases of healthy neonates were collected as the healthy control group (HC group). The ADC values were measured, and the ADC ratios (rADC value) were calculated in bilateral GPs and frontal white matter (FWM), and the number of low-signal foci (microbleeds) of 3D-SWAN were counted. The differences of MRI parameters between groups and their correlation with total serum bilirubin (TSB) were analyzed. Results: The rADC value of GP in HC group, HBn group and HBh group decreased successively (P＜0.05), while the difference between HC and HBh groups was significant (P＜0.05). Compared with HC group, the number of intrcerebral microbleeds (CMBs) in HB group was significantly increased (P＜0.05). The rADC value of HB group had a positive correlation with TSB (r=0.202, P=0.013). However, no correlation was found between the number of CMBs in HB group and TSB (P=0.278). Conclusions: The limited diffusion of water molecules is present in GP and related to the level of total bilirubin in children with HB. CMBs more likely occur in children with HB and need to attach importance to it during treatment.]]></description>
<pubDate>Fri,20 Nov 2020 00:00:00  GMT</pubDate>
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<title><![CDATA[Cardiac magnetic resonance right ventricular myocardial strain was applied to normal smoking population: a pilot study]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2020.11.009</link>
<description><![CDATA[Objective: To investigate the relationship between right ventricular (RV) myocardial strain (MS), right ventricular structural and functional parameters and smoking parameters in smoking volunteers with cardiac magnetic resonance (CMR). Materials and Methods: Forty-nine normal male smoking volunteers who underwent standard cardiac image acquisition in the First Affiliated Hospital of Dalian Medical University from May 2019 to January 2020 were prospective collected in the study. The detailed smoking status of each volunteer was recorded and summarized. All volunteers performed routine scans on a GE 3.0 T magnetic resonance scanner, including two-chamber, three-chamber, four-chamber and left ventricular (LV) short-axis movies. RVMS parameters including global radial strain (GRS), global circumferential strain (GCS), global longitudinal strain (GLS) and RV structure and functional parameters were measured. The correlation between RVMS, structural and functional parameters and smoking parameters were analyzed with Spearman correlation coefficient. Results: Smoking time was only positively correlated with RVGLS (r=0.324, P=0.023). Smoking intensity was positively correlated with RVGRS and RVGCS (r=0.374, P=0.008; r=0.345, P=0.015) and had a negative correlation with RV end-diastolic volume index (RVEDVi) and RV end-stolic volume index (RVESVi) (r=-0.318, P=0.026; r=-0.325, P=0.022). Smoking burden was positively correlated with RVGRS and RVGLS (r=0.298, P=0.037; r=0.372, P=0.009). Conclusions: Smoking can affect RV. With the increase of smoking time and smoking quantity, RVMS parameters may have a compensatory increase significantly under a certain load. There may be a compensatory mechanism of RV myocardium on the influence caused by smoking.]]></description>
<pubDate>Fri,20 Nov 2020 00:00:00  GMT</pubDate>
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<title><![CDATA[Study on the correlation between MRI features and KRAS status of rectal cancers before operation]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2020.11.010</link>
<description><![CDATA[Objective: To analyze whether the MRI features of rectal cancers can predict Kirsten Rat Sarcoma Viral Oncogene Homolog (KRAS) mutation status. Materials and Methods: Eighty-two patients who were confirmed to have rectal cancers by surgery and pathology and had undergone KRAS gene examination were collected retrospectively. The patients were divided into a mutant group and a wild-type group according to the mutation status of KRAS gene. Two doctors analyzed their MRI characteristics, including tumor location, gross morphology, periintestinal involvement, circumferential margin (CRM), tumor maximum longitudinal length (LTL), tumor maximum axial length (ATL), maximum axial length/maximum longitudinal length (ATL/LTL), ADC value, etc., and then analyze whether there are differences between the two groups. Results: The KRAS mutant group and the wild-type group had significant differences in tumor morphology, ATL and ATL/LTL (χ2=11.815, P=0.001; Z=-2.268, P=0.023; Z=-2.422, P=0.015). Larger ATL/LTL were more prone to KRAS gene mutation. ROC analysis between the two groups showed that the area under the curve (AUC) of ATL and ATL/LTL were 0.645 and 0.655, respectively. Conclusions: There were significant differences in ATL and ATL/LTL between KRAS mutant group and wild type group.]]></description>
<pubDate>Fri,20 Nov 2020 00:00:00  GMT</pubDate>
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<title><![CDATA[Magnetic resonance imaging as a tool to predict pathological complete response of rectal cancer after neoadjuvant chemoradiotherapy: a Meta-analysis]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2020.11.011</link>
<description><![CDATA[Objective: The aim of this study was to evaluate the predictive effect of MRI on the pathological complete response (pCR) of rectal cancer after neoadjuvant chemoradiotherapy. Materials and Methods: Comprehensive computer-based search was performed (last updated in June 2020), and the eligible studies were selected. Pooled sensitivity, specificity, positive likelihood ratio, negative likelihood ratio, diagnostic odds ratio (DOR) and the area under the hierarchical summary receiver-operating characteristic curves (AUC) were calculated to estimate the diagnostic accuracy of MRI. Methodological quality was assessed using the quality assessment of diagnostic accuracy studies (QUADAS-2) tool. Results: Thirty five studies with 2674 patients were included and analyzed. The results showed that pooled sensitivity, specificity of MRI were [0.75, 95% CI (0.70, 0.80)] and [0.86, 95% CI (0.82, 0.89)], respectively. Among the different sequences, diffusional kurtosis imaging had the highest sensitivity with the odds ratio (OR) of 0.84 (95% CI: 0.73, 0.91). T2-weighted imaging with dynamic contrast enhanced had the highest specificity than other sequences [0.96, 95% CI (0.89, 0.99)]. In addition, T2-weighted imaging with diffusion weighted imaging was associated with the highest DOR [47.56, 95% CI (23.64, 95.72)] and AUC [0.94, 95% CI (0.92, 0.96)]. The indirect comparison also showed T2-weighted imaging with diffusion weighted imaging was the best sequence to diagnose pCR. 1.5 T and 3.0 T were similar in sensitivity, specificity and AUC results. Conclusions: T2-weighted imaging with diffusion weighted imaging is superior to other sequences of MRI, and is the optimal choice for the diagnosis of the pCR of rectal cancer. Besides, there is no difference in the prediction effect of different magnetic intensities.]]></description>
<pubDate>Fri,20 Nov 2020 00:00:00  GMT</pubDate>
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<title><![CDATA[Analysis of the influencing factors on the ablation rate of uterine fibroid by using high intensity focused ultrasound]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2020.11.012</link>
<description><![CDATA[Objective: To explore the influencing factors of high intensity focused ultrasound (HIFU) in the treatment of uterine fibroid. Materials and Methods: Retrospectively collected clinical data of 130 patients with uterine fibroid admitted to the HIFU Center of the First Affiliated Hospital of Chongqing Medical University from January 2013 to December 2018, including the patient's age, volume of fibroids and mean meridian before treatment, fibroids location, fibroids type, MRI T2WI signal intensity and uniformity, T1WI enhancement intensity and uniformity, and uterine location, etc. The preoperative and postoperative MRI images were used to calculate the preoperative volume of the fibroids and the non-perfused area after the HIFU treatment to obtain the ablation rate. The indicators above were analyzed to find out the factors that affect the efficacy of HIFU ablation of uterine fibroids. Results: Of the 130 fibroids, 70 (53.8%) fibroids were sufficient ablated. Univariate analysis results showed that volume of fibroids, mean meridian of fibroids, T2WI signal intensity and uniformity, TIWI enhancement degree and uterine position had a statistically significant effect on ablation (P＜0.05). Multivariate logistic regression analysis showed that T2WI signal intensity (P=0.035) and TIWI enhancement (P=0.038) of fibroids were more likely to achieve satisfactory ablation results. Conclusions: The volume of fibroids, the average meridian of fibroids, the intensity and uniformity of T2WI signal, the degree of T1WI enhancement, and the position of the uterus all have a certain effect on the efficacy of HIFU in treating uterine fibroids. This study has a certain predictive effect on predicting the efficacy of HIFU ablation of uterine fibroids.]]></description>
<pubDate>Fri,20 Nov 2020 00:00:00  GMT</pubDate>
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<title><![CDATA[Limb remote ischemic preconditioning prolongs the existence window of graphic penumbra in cerebral ischemia rat model and its related mechanism: through inhibiting the expression of high mobility group protein 1]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2020.11.013</link>
<description><![CDATA[Objective: To investigate the effect of limb remote ischemic preconditioning (LRP) on the ischemic penumbra in a cerebral ischemia rat model, and to explore whether the neuroprotective effect of LRP might be related to the expression of high mobility group protein 1 (HMGB1). Materials and Methods: Seventy-two adult male Sprague-Dawley rats were randomized into 3 groups: cerebral ischemia group, LRP group and sham controls. All rats underwent MRI detection to acquire T2-FLAIR and diffusion-weighted imaging (DWI) data at different time points (1 h, 3 h, 6 h and 24 h). TTC staining and behavioral score were subsequently executed. Western Blot was used to detect the expression of HMGB1, and Real-time PCR was used to detect the transcription level of HMGB1. Results: LRP improved the behavioral outcomes (2.60±0.65 vs. 1.52±0.65, P＜0.001) and reduced the infarct size (68.04±13.24 vs. 29.02±23.62, P＜0.001). MRI results indicated that LRP could delay the lesion (P＜0.001) and prolong the existence window of the penumbra (P＜0.001).Western blot and PCR analysis showed that LRP down-regulated protein expression and transcription level of HMGB1 (P＜0.05). Conclusions: LRP can prolong the existence of penumbra in ischemic stroke, which may prolong the treatment time window. The neuroprotective effect of LRP is related to the expression of HMGB1.]]></description>
<pubDate>Fri,20 Nov 2020 00:00:00  GMT</pubDate>
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<title><![CDATA[The value of quantitative dynamic contrast enhanced MRI in the diagnosis of thyroid lesions]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2020.11.014</link>
<description><![CDATA[Objective: To explore the diagnosis values of quantitative dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) in thyroid lesions. Materials and Methods: According to the pathological results, the cases were divided into benign, malignant and normal groups. The differences of quantitative parameters of DCE between the three groups were analyzed. Results: A total of 22 patients were included in the analysis, including 5 benign lesions, 13 malignant lesions and 16 normal tissues. for transfer constant (Ktrans), rate constant (Kep), the malignant lesions showed higher values than benign lesions, volume of extravascular extra-cellular space per unit volume of tissue (Ve) takes contrary results, but no significant differences was found. Conclusions: There is no significant difference in the quantitative parameters of DCE between benign and malignant thyroid lesions. The specific diagnostic value of DCE needs to expand the sample size for further detection.]]></description>
<pubDate>Fri,20 Nov 2020 00:00:00  GMT</pubDate>
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<title><![CDATA[Research progress of DWI multi-model quantitative technique in glioma]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2020.11.019</link>
<description><![CDATA[Glioma is a kind of nervous system tumor originated from glial cells and neuron cells. Due to the advantages of non-radiation and high resolution of MRI, it is widely used in glioma grading, postoperative survival evaluation and treatment effect. Diffusion weighted magnetic resonance imaging is a technique that can quantify the diffusion of water molecules in micro tissues and show the microstructure changes of pathological tissues. It can be used to display the complex micro pathological changes of glioma, so it has been widely used in recent years. This paper introduces the basic concept of diffusion magnetic resonance imaging and its extended multi-model quantitative technique in clinical application.]]></description>
<pubDate>Fri,20 Nov 2020 00:00:00  GMT</pubDate>
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<title><![CDATA[Advances in research on resting brain network functional magnetic resonance imaging for PD with cognitive impairmente]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2020.11.020</link>
<description><![CDATA[Resting state functional magnetic resonance imaging (RS-fMRI) has been widely used to analyze the pathophysiology of neurodegenerative diseases such as Parkinson's disease (PD). Parkinson's patients with cognitive impairment experience changes in their functional network connections that can lead to cognitive decline.In this review, we attempt to summarize recent RS-fMRI studies and discuss the limitations and potential significance of functional connectivity features in early Parkinson's disease to track and predict future PD progression. Understanding the neurologic factors and potential triggers of clinical progression and complications is important to guide new clinical trials and develop prevention strategies.]]></description>
<pubDate>Fri,20 Nov 2020 00:00:00  GMT</pubDate>
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<title><![CDATA[Current status of spinal cord MRI study of amyotrophic lateral sclerosis]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2020.11.021</link>
<description><![CDATA[Amyotrophic lateral sclerosis (ALS) is the most common type of motor neuron disease (MND), showing continuous worsen. There is currently no effective treatment. Nursing and respiratory support have significantly improved the patient's quality of life and survival rate. However, due to the heterogeneity of clinical manifestations, the average time from symptom onset to diagnosis is long. In view of this, finding new biomarkers to assist diagnosis and prognosis assessment becomes particularly important. Magnetic resonance imaging is safe, noninvasive, and easy to collect, and is a reasonable choice as a biomarker. The vast majority of current ALS imaging studies focus on cerebral changes, which are limited to upper motor neurons. Spinal cord MRI can study both upper motor neurons and lower motor neurons at the same time, so it may be a sensitive marker for early disease.]]></description>
<pubDate>Fri,20 Nov 2020 00:00:00  GMT</pubDate>
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<title><![CDATA[Application of resting state fMRI in the study of the obstructive sleep apnea-hypopnea syndrome]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2020.11.022</link>
<description><![CDATA[Obstructive sleep apnea-hypopnea syndrome (OSAHS) is a common disease with chronic multi-system damage. The central nervous system (CNS) damage of OSAHS is mainly manifested as cognitive impairment and neuropsychiatric abnormality, which seriously affects the quality of life and safety of patients. However, the neuropathological mechanism of OSAHS has not been fully elucidated. Recently, resting state functional magnetic resonance imaging (rs-fMRI) and its advanced data processing methods have opened a new way for the study of OSAHS neuroimaging. This article makes a review to explore the potential neuropathic mechanisms of CNS damage in OSAHS patients and to provide valuable methods and evidence for early diagnosis and treatment.]]></description>
<pubDate>Fri,20 Nov 2020 00:00:00  GMT</pubDate>
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<title><![CDATA[Research progress of Gd-EOB-DTPA enhanced MRI in evaluating liver function]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2020.11.023</link>
<description><![CDATA[Magnetic resonance imaging plays an important role in the detection of liver diseases. Gadolinium-ethoxybenzyl-diethylenetriamine pentaacetic acid (Gd-EOB-DTPA) is one of the commonly used liver-specific contrast agents in clinical practice. It is not only of great significance in the detection of focal lesions, but also of potential application value in the assessment of diffuse liver damage. Quantitative evaluation of liver function in different segments based on anatomical information is more important for the selection of appropriate treatment for patients with chronic liver disease and liver cancer. In recent years, Gd-EOB-DTPA-enhanced magnetic resonance imaging has become more and more widely used in clinical practice, and its methods for assessing liver function mainly include measurement of relaxation time before and after enhanced, changes in liver parenchymal signal intensity, the biliary tract signal intensity and bile duct imaging time and measurement of contrast agent in bile duct. This article reviews the related research on the diagnostic value of Gd-EOB-DTPA enhanced magnetic resonance imaging for liver function.]]></description>
<pubDate>Fri,20 Nov 2020 00:00:00  GMT</pubDate>
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<title><![CDATA[Progress in the application of multimodal imaging technique in hepatic cystic hydatidosis]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2020.11.024</link>
<description><![CDATA[Hepatic cystic echinococcosis (HCE) is a zoonotic parasitic disease infected by echinococcus granulosus. It can occur in all organs, especially in the liver. It is distributed globally and is mainly popular in the southwest and northwest pastoral areas in China. The early symptoms of the disease are usually not obvious, but it causes great harm to human health when it develops to the later stages. This paper gives a brief review of the multimodal imaging and its application in HCE, in order to improve the understanding of early diagnosis and the treatment.]]></description>
<pubDate>Fri,20 Nov 2020 00:00:00  GMT</pubDate>
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<title><![CDATA[Advances in clinical application of radiomics in prostate cancer]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2020.11.025</link>
<description><![CDATA[Radiomics extract digital features from medical images using computer algorithm. Combining with machine learning method, prediction model was constructed and then assistant diagnosis and treatment. Currently, radiomics is supplied to the diagnosis and treatment of prostate cancer. In this article, I will make a review of the advances in clinical application of radiomics in prostate cancer.]]></description>
<pubDate>Fri,20 Nov 2020 00:00:00  GMT</pubDate>
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<title><![CDATA[Detection, stratification and differentiation of prostate cancer by intravoxel incoherent motion imaging]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2020.11.026</link>
<description><![CDATA[In recent years, the morbidity of prostate cancer has increased dramatically, so it is very important to make early diagnosis and judge the malignant degree of the tumor. Transrectal ultrasound guided biopsy is the gold standard for the diagnosis of prostate cancer, and it can also be classified pathologically, but it is invasive and may cause adverse side effects, so it is not the first choice. Multiparametric magnetic resonance imaging is the best imaging method for the diagnosis of early prostate cancer, among which diffusion-weighted imaging (DWI) is widely used to reflect the diffusion of water molecules in tissue and improve the detection rate of lesions. With the development of magnetic resonance imaging technology, the intravoxel incoherent motion (IVIM) model developed on the basis of DWI is gradually used in clinic. It uses a variety of b values and does not need intravenous injection of gadolinium contrast agent to obtain tissue diffusion and microcirculation perfusion information respectively. The potential value may be better than that of traditional DWI. This article reviews the role of IVIM imaging in prostate cancer.]]></description>
<pubDate>Fri,20 Nov 2020 00:00:00  GMT</pubDate>
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<title><![CDATA[Research progress of MRI in pelvic floor dysfunction]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2020.11.027</link>
<description><![CDATA[Pelvic floor dysfunction disease (PFD) refers to a series of diseases of pelvic anatomy and dysfunction caused by damage and degradation of pelvic floor supporting structure. MRI has a variety of examination techniques and methods for pelvic floor dysfunction diseases, which not only provides the basis for PFD anatomical and functional changes, but also helps explore pathophysiological changes. This article reviews the domestic and foreign literature on the progress of pelvic floor magnetic resonance, and describes the characteristics, current status and prospects of pelvic floor MRI imaging including static magnetic resonance imaging, dynamic magnetic resonance imaging, and functional magnetic resonance imaging.]]></description>
<pubDate>Fri,20 Nov 2020 00:00:00  GMT</pubDate>
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<title><![CDATA[Progress of blood oxygen level dependent magnetic resonance imaging in kidney disease]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2020.11.028</link>
<description><![CDATA[Blood oxygen level dependent magnetic resonance imaging (BOLD MRI) is a technique for obtaining tissue oxygen content by measuring the content of deoxyhemoglobin in the blood, which could reflect the hemodynamic and pathophysiological changes of tissues and organs and provide a non-invasive and reproducible examination method for clinical diagnosis, treatment and scientific research. Because BOLD MRI has been used in clinical studies on kidney diseases such as ischemic nephropathy, chronic kidney disease, stage of diabetic nephropathy and assessment of renal function. This article reviews the progress of clinical research in the past 5 years.]]></description>
<pubDate>Fri,20 Nov 2020 00:00:00  GMT</pubDate>
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<title><![CDATA[Progress of MRI in identifying benign and malignant vertebral compression fractures]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2020.11.029</link>
<description><![CDATA[Clinical treatment principles and prognosis of benign and malignant vertebral compression fractures (vertebral compression fractures, VCFs) are dramatically different, which is of great significance to accurately distinguish the two. In recent years, with the development and application of MRI technology (e.g. diffusion weighted imaging, dynamic contrast-enhanced imaging, and chemical-shift), especially the development of new radiomics technology, the characteristics of imaging features have been greatly improved, thereby improving the accuracy of differential diagnosis of benign and malignant VCFs. The purpose of this article is to review the application of MRI techniques and radiomics in the differential diagnosis of benign and malignant VCFs.]]></description>
<pubDate>Fri,20 Nov 2020 00:00:00  GMT</pubDate>
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