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<title>Chinese Journal of Magnetic Resonance Imaging RSS feed</title>
<link>http://med-sci.cn/cgzcx/en/contents_list.asp?issue=202111</link>
<language>zh-cn</language>
<copyright>An RSS feed for Chinese Journal of Magnetic Resonance Imaging</copyright>
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<title><![CDATA[Diagnostic value of texture analysis based on diffusion tensor imaging in Parkinson<sup><sup>,</sup></sup>s disease]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2021.11.001</link>
<description><![CDATA[Objective: To investigate the diagnostic value of texture analysis of gray matter nuclei and white matter on diffusion tensor imaging (DTI) in Parkinson<sup><sup>,</sup></sup>s disease (PD) and its correlation with the development of PD. Meterials and Methods: Thirty PD patients and 22 normal controls were prospectively collected for DTI scanning. The fractional anisotropy (FA) diagrams of the two groups were obtained by post-processing. The regions of interest (ROI), including bilateral caudate head, globus pallidus, putamen, substantia nigra, red nucleus, dentate nucleus and centrum semiovale, were delineated by ITK-SNAP software. The texture features were extracted by A.K software. The Mann Whitney U test, Univariate logistic regression analysis, mRMR (maximum relevance minimum redundancy) was applied to select 5 texture features with the highest joint diagnostic efficiency, and random forest (RF) was constructed. Receiver operating characteristic (ROC) curve analysis was used to evaluate the diagnostic efficiency of the model; besides, the cross-validation method was employed to verify the reliability of the model. In addition. The texture features obtained by dimensionality reduction were analyzed by Pearson correlation with mini mental state examination (MMSE), unified Parkinson<sup><sup>,</sup></sup>s Disease Rating Scale (UPDRS) and course of disease, and Spearman correlation with Hoehn-Yahr (H-Y) stages. Results: Five texture features were obtained after dimensionality reduction, and AUC (area under the curve) of independent prediction of Parkinson<sup><sup>,</sup></sup>s disease was ranging from 0.692 to 0.871 by ROC analysis. The AUC, accuracy, sensitivity and specificity of the Parkinson<sup><sup>,</sup></sup>s disease prediction model were 0.92, 0.86, 0.89, 0.84, respectively. The accuracy, sensitivity and specificity of cross-validation were 0.89, 0.84, 0.94, respectively. No significant correlation was found between the five texture features and the clinical scale of disease. Conclusions: Texture analysis based on DTI has a high diagnostic value for PD. However, the value for evaluating the disease development is limited.]]></description>
<pubDate>Sat,20 Nov 2021 00:00:00  GMT</pubDate>
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<title><![CDATA[Study on long-rage and short-rage functional connectivity strength of brain network hubs in patients with subcortical ischemic vascular disease]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2021.11.002</link>
<description><![CDATA[Objective: To explore the characteristics of long-rage and short-rage functional connectivity strength (FCS) of brain network hubs in patients with subcortical ischemic vascular disease (SIVD). Materials and Methods: Thirty patients with SIVD and 22 normal controls (NC) were scanned with resting-state functional magnetic resonance imaging. Maps of long-rage, short-rage FCS and brain network hubs were obtained by calculation. The difference of the long-rage and short-rage FCS of brain network hubs between groups were compared and the relationship between difference and cognitive function scores were assessed. Results: Brain network hubs were mainly distributed in cuneus lobe, precuneus lobe, lingual gyrus, middle cingulate gyrus, posterior cingulate gyrus, fusiform gyrus and calcarine. Compared with NC group, the long-rage and short-rage FCS values of the bilateral superior temporal gyrus, calcarine and the short-rage FCS values of the right insula decreased, the long-rage and short-rage FCS values of the right superior frontal gyrus and the long-rage FCS values in the right precuneus increased in SIVD group (all P＜0.05). In SIVD group, the long-rage FCS values of the right superior temporal gyrus (r=0.438, P=0.022) and the short-rage FCS values of right insula (r=0.390,P=0.044) were correlated with cognitive function scores. Conclusions: There are abnormal long-rage and short-rage FCS changes in some brain network hubs of patients with SIVD, especially in insula and superior temporal gyrus, which may help to reveal its neural mechanism.]]></description>
<pubDate>Sat,20 Nov 2021 00:00:00  GMT</pubDate>
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<title><![CDATA[Study on plaque characteristics of basilar artery with mild and severe curvature based on HR-MRI]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2021.11.003</link>
<description><![CDATA[Objective: To study the differences in the distribution, size and composition of basilar artery (BA) plaques using high resolution magnetic resonance imaging (HR-MRI) among patients with mild and severe BA curvature. Materials and Methods: By three-dimension time of flight magnetic resonance angiography (3D-TOF-MRA), patients with BA curvature were included in the study. The transverse distance from the outer wall of the vessel at the maximum curvature of BA to both ends of BA (the junction line between the top of BA and the confluence of the left and right vertebral arteries) was measured and divided into mild curvature group (5 mm＜transverse distance＜10 mm) and severe curvature group (transverse distance≥10 mm). Clinical factors, plaque distribution (inner arc, outer arc), size (minimal plaque, apparent plaque) and composition [intraplaque hemorrhage (IPH)] were compared between the two groups. Results: Ninety-two patients with 106 plaques were enrolled, including 54 patients with 60 BA plaques in the mild BA curvature group and 38 patients with 46 BA plaques in the severe BA curvature group. BA plaques were common in the inner arc between the two groups (inner arc vs. outer arc: 76.7%, 73.9% vs. 23.3%, 26.1%). The plaques were more obvious in the severe BA curvature group than in the mild BA curvature group (severe vs. mild: 65.2% vs. 36.7%), and the difference was statistically significant (P=0.004). The proportion of IPH in the severe BA curvature group was higher than that in the mild BA curvature group (severe vs mild: 69.6% vs. 25.0%), and the difference was statistically significant (P＜0.001). There were no statistically significant differences in clinical related factors between the two groups (P＞0.05). Conclusions: The curved basilar atherosclerotic plaques are mostly distributed in the inner arc. Apparent plaques are more likely to occur in the severe BA curvature group than in the mild BA curvature group, and the proportion of IPH in the severe BA curvature group is higher than that in the mild BA curvature group, and the plaque in the mild BA curvature group is more stable.]]></description>
<pubDate>Sat,20 Nov 2021 00:00:00  GMT</pubDate>
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<title><![CDATA[Preliminary study of quantitative susceptibility mapping in the brain iron deposition of unilateral middle cerebral artery stenosis or occlusion]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2021.11.004</link>
<description><![CDATA[Objective: The MR quantitative susceptibility mapping (QSM) was used to explore the iron deposition of brain gray matter nucleus in patients with unilateral middle cerebral artery (MCA) stenosis or occlusion. Materials and Methods: Thirty-three patients with unilateral MCA stenosis or occlusion underwent QSM and conventional MRI scan by GE 3.0 T MR. After processing the original images, QSM images were obtained. Susceptibility values of bilateral caudate nucleus, putamen, globus pallidus and thalamus were measured and compared between the lesion side and the contralateral side by paired sample t-test. According to the degree of lumen stenosis, the 33 patients were divided into mild and moderate stenosis group, severe stenosis group and occlusion group. One-way analysis of variance was used to compare the differences of susceptibility values of gray matter nucleus in the three groups. Results: There was significant difference in susceptibility values of caudate nucleus, putamen and globus pallidus between the lesion side and the contralateral side in 33 subjects (P＜0.05), while there was no significant difference in susceptibility values of thalamus on both sides (P＞0.05). And there was no statistical significance among the above three groups (P＞0.05). Conclusions: The QSM technique found that the iron content in gray matter nucleus of the lesion side in patients with unilateral MCA stenosis or occlusion was higher than the contralateral side, which further deepens the understanding of the pathophysiological changes of ischemic stroke and provides guidance for clinical treatment and improvement of the prognosis of ischemic stroke.]]></description>
<pubDate>Sat,20 Nov 2021 00:00:00  GMT</pubDate>
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<title><![CDATA[A preliminary study of cardiac magnetic resonance myocardial strain technique in the left atrium of normal male smokers]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2021.11.005</link>
<description><![CDATA[Objective: To assess the left atrial (LA) structure, function and myocardial strain (MS) between normal male smokers and non-smokers using cardiac magnetic resonance (CMR) MS technique. Materials and Methods: Seventy normal male volunteers underwent conventional heart scanning in 3.0 T magnetic resonance in our hospital were enrolled in this study. They were divided into a smoker group (44 volunteers) and a non-smoker group (26 volunteers). General information and clinical data were documented. The left atrial (LA) structure, function and MS parameters were measured by Medis Suite software. MS parameters included global longitudinal strain (GLS), global radial strain (GRS), and global circumferential strain (GCS). We compared the differences in LA structure, function and MS parameters between the non-smoker group and smoker group. Results: LA MS parameters showed good consistency within and between the group (ICC≥0.75). GCS and GRS in smoker group were significantly lower than in non-smoker group (33.81%±11.23% vs. 40.21%±11.84%, -28.99%±4.95% vs. -31.66%±4.75%, all P＜0.05). There was no statistically difference in LA structure and function parameters between two groups. Conclusions: In contrast with non-smoker volunteers, LA GCS and GRS of smoker volunteers were damaged to a certain extent, before the changes of LA structure and function.]]></description>
<pubDate>Sat,20 Nov 2021 00:00:00  GMT</pubDate>
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<title><![CDATA[The value of T1 mapping and ECV in the diagnosis of acute pancreatitis and recurrent acute pancreatitis: a primary study]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2021.11.006</link>
<description><![CDATA[Objective: To investigate the diagnostic value of T1 mapping imaging and extracellular volume fraction (ECV) in acute pancreatitis (AP) and recurrent acute pancreatitis (RAP). Materials and Methods: The patients who underwent pancreatic MRI and T1 mapping examination were respectively analyzed between December 2018 and June 2020 in our hospital. The enrolled cases were grouped as AP group (40 cases) and normal control group (22 cases). Additionally, the cases in AP group were divided into two subgroups: single acute pancreatitis (SAP) (20 cases) and RAP (20 cases) according to the frequency of AP attacks. T1 relaxation times before and after enhancement in pancreatic parenchyma (T1pre pancreas and T1post pancreas) and abdominal aorta on the same slice (T1pre blood and T1post blood) were measured and the value of pancreatic enhancement ratio (PER) and ECV were calculated in all patients. The Mann-Whitney U-test and independent t-test were applied to compare the differences of these parameters between AP group and normal control group as well as SAP group and RAP group. Results: AP group tend to have higher values of T1pre pancreas, T1post pancreas, PER and ECV [(1145.20±25.90) ms, (473.50±13.20) ms, 0.65±0.00, 0.39±0.00 respectively] than that in normal control group [(802.20±12.20) ms,(434.60±8.40) ms, 0.38±0.00, 0.28±0.00 respectively], which were statistically significant between the two groups (P＜0.05). However, only the value of ECV was statistically significant between SAP group (0.35±0.20) and RAP group (0.41±0.10) (P=0.01). Conclusions: T1 mapping parameters and ECV are effective quantitative imaging parameters for diagnosis of acute pancreatitis and recurrent acute pancreatitis.]]></description>
<pubDate>Sat,20 Nov 2021 00:00:00  GMT</pubDate>
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<title><![CDATA[Multiparametric MRI radiomics signature for prediction of KRAS gene mutation in rectal cancer]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2021.11.007</link>
<description><![CDATA[Objective: To explore the value of multiparametric MRI imaging omics signal model to predict KRAS gene mutation in rectal cancer (RC). Methods and Materials: The clinicopathological data and the multi-parameter MRI imaging features of 104 patients with histopathological proven RC and preoperative MRI were retrospective recruited from Apr. 2019 to Dec. 2020. The association of clinicopathological characteristics and radiomics features with KRAS gene were evaluated using t test, χ2 test or Mann-Whitney U test. Least absolute shrinkage and selection operator (LASSO) regression was harnessed for radiomics features selection and radiomics signature building. Prediction performance of radiomics signature for KRAS gene mutation was assessed by using area under the curve (AUC) of receiver operating characteristic (ROC). Results: The associations of clinicopathological characteristics and KRAS gene mutation were not statistical significant. Univaraite analysis revealed that 16 of the 321 radiomics features were related to KRAS mutation. LASSO regression selected 7 features for radiomics signature building. The radiomics signature yielded AUC of 0.81 (95% CI: 0.70—0.92) and 0.77 (95% CI: 0.63—0.91, P=0.60) for predicting KRAS mutation in training and validation sets, among them, the maximum λ coefficiences of the first-order skewness in the ADC feature is 3.36. Conclusions: MRI radiomics signature could be used as surrogate biomarker for predicting KRAS mutation in RC, among them, the first-order skewnes of ADC features has the best predictive performance.]]></description>
<pubDate>Sat,20 Nov 2021 00:00:00  GMT</pubDate>
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<title><![CDATA[Clinical value of MRI-based scoring system in predicting placenta accreta spectrum disorders]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2021.11.008</link>
<description><![CDATA[Objective: To investigate the clinical value of MRI-based scoring system in predicting placenta accreta spectrum disorders. Materials and Methods: The data of 102 pregnant women suspected of placenta accreta spectrum disorders in our hospital were analyzed retrospectively. Nine items including MRI signs and clinical risk factors were selected to develop the MRI-based scoring system in predicting placenta accreta spectrum. Calculate average total score of each type of placenta implantation. The variance analysis and least-significant difference were used for comparison among groups and the ROC curve was drawn to calculate the cut-off score of each type of placenta implantation. Results: Among 102 pregnant women, there were 35 cases of non-implantation type, score was (2.94± 1.28), 28 cases of placenta accreta type, score was (5.54±1.75), 32 cases of placenta increta type, score was (9.88±2.37), and 7 cases of placenta percreta type, score was (13.57±1.90). There was statistically significant difference in scores among all groups (F=115.688, P< 0.05). The ROC curve showed that the cut-off score between non-implantation and placenta accreta, between placenta accreta and placenta increta, and between placenta increta and placenta percreta were 3.5, 7.5, and 10.5, respectively. Conclusions: MRI-based scoring system has a good value in predicting placenta accreta spectum disorders and depth of placenta imlantation.]]></description>
<pubDate>Sat,20 Nov 2021 00:00:00  GMT</pubDate>
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<title><![CDATA[Cerebellar-cortical functional connectivity abnormalities in individuals with nicotine dependence]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2021.11.009</link>
<description><![CDATA[Objective: To explore the neuromechanism of nicotine dependence (ND), this study used resting-state functional magnetic resonance imaging (rs-fMRI) to analyze cerebellar-cortical functional connectivity (FC) abnormalities in long-term smokers. Materials and Methods: One hundred and seventeen long-term smokers and 52 non-smoking volunteers matched with age and education were recruited through the network platform. Using rs-fMRI data, we chose bilateral CrusⅠ as the region of interest (ROI), and calculated the FC between bilateral Crus Ⅰ and other brain regions to compare the differences of cerebellar-cortical FC between smokers and healthy controls (HCs). Results: Compared with HCs, we found increased FC between the left CrusⅠ and brain regions involved in the default mode network (DMN), sensory and motor system in smokers (t=3.56, clusters≥20). The FC between right CrusⅠ and cortex in smokers were not significantly different from those in HCs. Conclusions: Long-term smokers showed multiple abnormalities in cerebellar-cortical functional connectivity, and these may be the underlying neuromechanism of nicotine dependence, which are associated with automatized smoking behavior, cognitive and attention deficits.]]></description>
<pubDate>Sat,20 Nov 2021 00:00:00  GMT</pubDate>
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<title><![CDATA[Correlative analysis of glycemic variability and brain stracture and cognitive function in type 2 diabetic patients]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2021.11.010</link>
<description><![CDATA[Objective: To investigate the correlation between glycemic variability and brain structure and cognitive function in patients with type 2 diabetes mellitus (T2DM). Materials and Methods: Seventy-one T2DM patients in our hospital were selected, and 70 healthy controls (HC) were recruited at the same time. All participants completed MRI scans and cognitive function tests. Among them, 36 of T2DM patients completed the collection of glycemic variability data through continuous glucose monitoring. Using 3.0 T MRI to obtain 3D T1 images, the two groups of gray matter volumes were statistically compared based on the cluster level, and the gray matter volume values of different brain regions were extracted, and the partial correlation analysis was used to analyze the gray matter volume values and glycemic variability indicators and cognitive test scores, in which gender, age and education level were used as covariates. Results: Compared with the control group, the volume of gray matter in the right cerebellum 4/5 area, left caudate, left thalamus, left middle frontal gyrus and left medial superior frontal gyrus were decreased and multiple cognitive test scores were reduced in the T2DM group (P＜0.05). In T2DM group, correlation between brain gray matter volume and cognitive test scores: the gray matter volume of the left caudate was negatively correlated with TMT_A (Pr=-0.276, P=0.023). The gray matter volume of the left thalamus was positively correlated with AVLT (delay) (Pr=0.251, P=0.039). The gray matter volume of the left medial superior frontal gyrus was positively correlated with DST_forward (Pr=0.258, P=0.034). Correlation between brain gray matter volume and glycemic variability index: SDBG was negatively correlated with the left caudate and the left medial superior frontal gyrus (Pr=-0.449, P=0.009; Pr=-0.376, P=0.031). Correlation between glycemic variability index and cognitive test scores: MBG was negatively correlated with SDMT and VFT (Pr=-0.357, P=0.042; Pr=-0.374, P=0.032). SDBG was negatively correlated with DST_forward (Pr=-0.465, P=0.006). CV was negatively correlated with DST_forward (Pr=-0.383, P=0.028). MODD was negatively correlated (Pr=-0.562, P=0.002). TIR was positively correlated with DST_forward (Pr=0.406, P=0.032). Conclusions: T2DM patients had gray matter volume atrophy in different brain regions and cognitive function decline. We also found that the greater of the glycemic variability, the more obvious of the gray matter atrophy and the worse the cognitive level of T2DM patients.]]></description>
<pubDate>Sat,20 Nov 2021 00:00:00  GMT</pubDate>
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<title><![CDATA[The clinical application value of constellation shuttling imaging technology based on T1W-3D sequence]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2021.11.011</link>
<description><![CDATA[Objective: To explore the clinical application value of constellation shuttling imaging technology in cranial magnetic resonance scanning. Materials and Methods: Brain imaging of 20 healthy adult volunteers on a United Imaging uMR780 3.0 T superconducting magnetic resonance, with 24-channel phased array coils, from July to August 2020, this study recruited without contraindications to magnetic resonance scanning, including 10 males and 10 females, aged 22—69 (40.2±13.3) year old. Two radiologists with an attending physician level or above perform subjective image quality assessment without knowing the image sequence information: based on visual assessment, comprehensive signal-to-noise ratio, artifacts, and the definition of gray matter borders, they perform Likert 5-level scoring. The data results were tested by kappa. Place the region of interest (ROI) in the gray matter (GM,) and white matter (WM) and background noise regions corresponding to the anatomical structure, and repeat the intensity of the gray matter, white matter signal and noise signal (noise signal), take the average of the three measurements and calculate the SNR and CNR. Using the voxel-based morphometrics CAT-12 software to obtain the total brain parenchymal volume, total gray matter volume, total white matter volume, and total cerebrospinal fluid volume. All of the above uses the statistical software version SPSS 23.0 to perform Paired t test, and the difference is statistically significant with P＜0.05. Results: The image quality of the included study Likert grade 5 score (4—5 points), the test score result: Kappa value is 0.801, P value is less than 0.001, it is considered that the image quality evaluation results of the two doctors are statistically consistent. For SNR and CNR, a t test was performed to compare the two sets of data. The results showed that the signal-to-noise ratio between the two was statistically different, and the light shuttle imaging technology group was higher than the parallel acquisition technology group. Using the voxel-based morphometrics CAT-12 software to obtain the total brain parenchymal volume, total gray matter volume, total white matter volume, and total cerebrospinal fluid volume, paired t-test was performed, and the P values were 0.98, 0.25, 0.50, 0.11, respectively. Both are greater than 0.05. There is no significant difference between the two groups of different scanning methods based on the voxel-based morphometric results in statistical significance. The scanning time of the constellation shuttling imaging technology is reduced by 116 s, which is reduced to 40%. Conclusions: Compared with the traditional parallel acquisition technology, the constellation shuttling imaging technology has a better image signal-to-noise ratio in the skull T1W sequence than the parallel acquisition technology, and can significantly shorten the scanning time, which has important clinical application value.]]></description>
<pubDate>Sat,20 Nov 2021 00:00:00  GMT</pubDate>
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<title><![CDATA[Application value of functional magnetic resonance in early diagnosing autoimmune encephalitis in and evaluating the prognosis in children]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2021.11.012</link>
<description><![CDATA[Objective: To explore the early diagnostic and prognostic value of functional magnetic resonance imaging (fMRI) in children with autoimmune encephalitis (AE). Materials and Methods: From January 2018 to May 2019, 50 children with AE and 80 children with viral encephalitis (VE) who were admitted to the Affiliated Hospital of Inner Mongolia Medical University Hospital were selected as the AE group and the VE group, respectively. MRI scans, diffusion weighted imaging (DWI), arterial spin label (ASL) perfusion imaging and 1H-magnetic resonance spectroscopy (1H-MRS) were performed respectively. The relative apparent diffusion coefficient (rADC) values of the lesion area, the normal area and the two relative ADC values were measured using DWI images, relative cerebral blood flow (rCBF) using ASL, and choline (Cho) near 2.01 ppm, N-Acetyl-L-aspartic acid (NAA) near 2.01 ppm, creatine (Cr) near 3.03 ppm and other markers and the areas under the peaks of CHo/NAA, Cho/Cr, and NAA/Cr using 1H-MRS image; the relative ratio of the area of the markers was calculated. The children with VE were grouped according to the different prognosis, and the SPSS 22.0 statistical software package was used for data analysis. ROC curve was established to analyze the diagnostic value of each functional parameter for VE and the predictive value of the prognosis of the children. Results: The values of rADC and NAA/Cr in the AE group were higher than those in the VE group, and the values of relative regional cerebral blood flow (rrCBF) and Cho/Cr were lower than those in the VE group (t=17.979, 7.250, 4.982, 5.174, P＜0.05). There was no significant difference in Cho/NAA between the two groups (P＞0.05). The values of rADC and rCBFof children with poor prognosis VE were higher than those with good prognosis, and values of NAA/Cr were lower than those with good prognosis (t=2.835, 2.282, 2.162, P＜0.05). Conclusions: The rADC value in DWI, the rrCBF value in ASL, and the NAA/Cr value in 1H-MRS have a certain application value in the early differential diagnosis of AE and VE, and may reflect the prognosis of children with AE to a certain extent.]]></description>
<pubDate>Sat,20 Nov 2021 00:00:00  GMT</pubDate>
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<title><![CDATA[MRI features identify combined hepatocellular-cholangiocarcinoma and intrahepatic cholangiocarcinoma with arterial rim enhancement]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2021.11.013</link>
<description><![CDATA[Objective: To identify the MRI features of combined hepatocellular-cholangiocarcinoma (cHCC-CCA) and intrahepatic cholangiocarcinoma (ICC) with arterial rim enhancement, so as to provide some references for the preoperative differential diagnosis. Material and Methods: Seventy cHCC-CCA patients and 74 ICC patients confirmed by pathology were included in this study. Their contrast-enhanced MRI showed the arterial rim enhancement. The clinicopathological data and MRI characteristics of patients with cHCC-CCA and ICC were analyzed retrospectively. The differences of clinicopathological and MRI characteristics between cHCC-CCA and ICC patients were also compared. Results: In this study, the incidence of intratumoral hemorrhage (25.7% vs. 9.5%, P=0.010), non-peripheral washout (51.4% vs. 9.5%, P＜0.001), enhancing capsule (60.0% vs. 14.9%, P＜0.001), nodule-in-nodule architecture (7.1%vs. 0%, P=0.025), and mosaic architecture (51.4% vs. 2.7%, P＜0.001) in cHCC-CCA with arterial rim enhancement were significantly higher than those of ICC. In contrast, the prevalence of target sign on DWI sequence (25.7% vs. 52.7%, P=0.001), delayed central enhancement (38.6% vs. 82.4%, P＜0.001) and hepatic capsule retraction (31.4% vs. 55.4%, P=0.004) in cHCC-CCA were significantly lower than those of ICC. Conclusions: MRI features including non-peripheral washout, enhancing capsule, nodule-in-nodule architecture, and mosaic architecture, combined with elevated AFP, will be helpful to distinguish the cHCC-CCA with arterial rim enhancement from ICC.]]></description>
<pubDate>Sat,20 Nov 2021 00:00:00  GMT</pubDate>
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<title><![CDATA[The value of whole-lesion histogram analysis of MR images in differentiating uterine cellular leiomyoma from degeneration of uterine leiomyoma]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2021.11.014</link>
<description><![CDATA[Objectives: To assess the utility of whole-lesion histogram of multiple MRI sequences for differentiating uterine cellular leiomyoma (UCL) from degeneration of uterine leiomyoma (UL-D). Materials and Methods: Fourty eight patients with UCL and fourty four patients with UL-D from March 2016 to April 2021, who underwent preoperative routine pelvic MRI sequences and diffusion weighted imaging (DWI), were retrospectively evaluated. Two experienced radiologists manually delineated the volume of interest (VOI) by MaZda package in T2 weighted imaging (T2WI) and ADC images, and the values derived from whole-lesion histogram analysis (including mean, variance, skewness, Perc 1%, Perc 10%, Perc 50%, Perc 90%, Perc 99%) were measured for each volume of interest (VOI). The consistency of assessment between the two radiologists was evaluated by using intra-class correlation coefficients (ICC), the MR variables were selected to build Logistic regression model. Receiver operating characteristic (ROC) curve analysis was performed to evaluate the diagnostic performance of single variable and Logistic regression model to differentiate UCL from UL-D. Results: The intra-class correlation coefficients between radiologists was 0.844, the features of mean, variance, skewness, Perc 1%, Perc 10%, Perc 50%, Perc 90%, Perc 99% extracted from ADC maps and features of variance, kurtosis, Perc 1% extracted from T2WI images showed statistically significant (P＜0.05). The area under the curve (AUC) were 0.833, 0.677, 0.674, 0.736, 0.777, 0.824, 0.848, 0.822 and 0.705, 0.660, 0.640 for each feature respectively. The T2WI, ADC, T2WI combined ADC Logistic regression models were built to differentiate UCL from UL-D, created AUCs of 0.790, 0.848, 0.881 respectively, with corresponding Youden<sup><sup>,</sup></sup>s index were 0.4830, 0.6250, 0.6288. Pairwise comparison of ROC curves of each model, the P values were 0.3425, 0.0394, 0.2348 for T2WI vs. ADC, (T2WI+ADC) vs. T2WI, (T2WI+ADC) vs. ADC respectively. Conclusions: Whole-lesion histogram analysis of T2WI and ADC gray-level images may assist in differentitating between UCL and UL-D patients. The combined model of ADC and T2WI created larger AUC than other models, but was not superior to ADC variables.]]></description>
<pubDate>Sat,20 Nov 2021 00:00:00  GMT</pubDate>
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<title><![CDATA[Evaluation of Her-2 gene expression in endometrial carcinoma by amide proton transfer weighted and fat quantitative]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2021.11.015</link>
<description><![CDATA[Objective: To explore the value of amide proton transfer weighted (APTw) imaging and fat quantitative measurement (mDIXON-Quant) techniques in evaluating the expression of human epidermal growth factor receptor-2 (Her-2) gene in endometrial carcinoma (EC). Materials and Methods: The data of 26 patients with EC confirmed by operation and pathology were retrospectively analyzed, including 11 cases in Her-2 positive group and 15 cases in Her-2 negative group. 3.0 T MR examination was performed before operation. The scanning sequence included APTw and mDIXON-Quant. After scanning, the APT map of APTw sequence and R2* map, fat fraction (FF) map of mDIXON-Quant sequence were obtained by post-processing. The values of APT, R2* and FF of the two groups were measured by two observers respectively. Intra-class correlation coefficients (ICC) was used to test the consistency of the two observers<sup><sup>,</sup></sup> measurement results of the parameters of the two groups. The differences of each parameter value of the two groups were compared by using the independent sample t test or Mann Whitney U test. ROC curve was used to evaluate the efficiency of the parameters with statistical difference evaluating the expression of Her-2 gene in EC. Area under the curve (AUC), corresponding cut-off value, sensitivity and specificity were calculated. Results: The data measured by two observers were consistent (ICC＞0.75).The values of APT, R2* and FF in the Her-2 positive group were 2.850% (2.300%, 2.900%)、 (17.102±2.333) Hz and 1.629%±1.086%, respectively. The above parameters were 2.313%±0.415%、(15.134±1.854) Hz and 1.476%±1.131% respectively in the Her-2 negative group. The APT, R2* values of Her-2 positive group were higher than those in the Her-2 negative group, the difference was statistically significant (P＜0.05). There was no statistically significant difference in FF values between the two groups (P＞0.05). The AUC of APT, R2* values in evaluating the expression of Her-2 gene in EC were 0.755 and 0.739, the cutoff value were 2.475% and 16.503 Hz, the sensitivity were 72.7% and 63.6%, the specificity were 80.0% and 86.7%, respectively. Conclusions: APTw and mDIXON-Quant have the potential to evaluate the expression of EC Her-2 gene half quantitatively, and have certain clinical application value.]]></description>
<pubDate>Sat,20 Nov 2021 00:00:00  GMT</pubDate>
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<title><![CDATA[Orbital and craniocerebral magnetic resonance imaging promotes precise diagnosis and treatment of retinoblastoma: the interpretation of a consensus on imaging examination and diagnosis of retinoblastoma]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2021.11.016</link>
<description><![CDATA[Magnetic resonance imaging (MRI) is the best noninvasive method for evaluating extraocular or optic nerve invasion of retinoblastoma (RB), which plays a vital role in the diagnosis and staging of RB and provides essential evidence for eyeball enucleation. This article summarized the advantages and value of MRI in diagnosis, differential diagnosis, and staging of RB, based on the expert consensus on imaging examination and diagnosis and selective ophthalmic artery infusion in patients with retinoblastoma. The details of MRI findings of high-risk factors of RB, key points of T staging of AJCC (8th edition), key parameters of MRI scanning, and the value of the ocular surface coil were also delineated, in order to help readers to understand the consensus and to make clinical decision.]]></description>
<pubDate>Sat,20 Nov 2021 00:00:00  GMT</pubDate>
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<title><![CDATA[Research progress of functional magnetic resonance imaging of resting brain network in supplementary motor area of Parkinson<sup><sup>,</sup></sup>s disease]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2021.11.022</link>
<description><![CDATA[Resting functional magnetic resonance imaging (rs-fMRI) has been extensively applied to analyze the pathophysiology of neurodegenerative disorders such as Parkinson<sup><sup>,</sup></sup>s disease (PD). The symptoms of patients with Parkinson<sup><sup>,</sup></sup>s disease include motor symptoms and non-motor symptoms. Supplementary motor area (SMA) is related to the pathophysiology of Parkinson<sup><sup>,</sup></sup>s disease. In this review, we summarize rs-fMRI studies related to SMA in PD patients, reflecting changes in brain network reorganization and adaptation to track and predict the progression of Parkinson<sup><sup>,</sup></sup>s disease.]]></description>
<pubDate>Sat,20 Nov 2021 00:00:00  GMT</pubDate>
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<title><![CDATA[Magnetic resonance research progress in amnestic mild cognitive impairment]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2021.11.023</link>
<description><![CDATA[Alzheimer disease (AD) is a progressive age-related neurodegenerative disease. Mild cognitive impairment (MCI) is a transitional stage between the normal aging process and AD. It is divided into amnestic MCI (aMCI) and non-amnestic MCI. The former is mainly memory impairment, which is considered to be the early stage of AD. The clinical subtypes of aMCI include single-domain (SD) and multi-domain (MD). Different subtypes have different possibilities to progress to AD. At present, the etiology and pathogenesis of AD are unclear, and there is no effective cure. Therefore, early diagnosis, intervention and treatment of aMCI and delay its progression to AD are of great significance. In recent years, magnetic resonance imaging combined with different analysis methods have been applied to the study of aMCI mechanism, which can objectively and indirectly reflect the abnormality of brain structure and functional activity, and provide certain clues for explaining its mechanism. Therefore, this article reviews the progress of aMCI magnetic resonance imaging studies.]]></description>
<pubDate>Sat,20 Nov 2021 00:00:00  GMT</pubDate>
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<title><![CDATA[Research progress of brain magnetic resonance imaging in patients with obstructive sleep apnea hypopnea syndrome]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2021.11.024</link>
<description><![CDATA[As a kind of common sleep disorders, obstructive sleep apnea hypopnea syndrome (OSAHS) may cause multi-system injury especially the central nervous system and seriously affect the prognosis of patients. The main clinical manifestations of OSAHS are fragmented sleep and chronic intermittent hypoxia. The application and research progress about magnetic resonance quantitative technology of brain injury in OSAHS patients were described, so as to improve the further understanding of the disease, provide objective basis for clinical diagnosis, guide clinical intervention as soon as possible, and reduce various complications.]]></description>
<pubDate>Sat,20 Nov 2021 00:00:00  GMT</pubDate>
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<title><![CDATA[Advances in brain magnetic resonance imaging of postpartum depression]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2021.11.025</link>
<description><![CDATA[At present, the pathogenesis of central nervous system of postpartum depression (PPD) is not clear, and there is a lack of objective indicators for diagnosis and prognosis. The continuous development of MRI technology provides an important tool for in-depth study of the neuropathological mechanism and neuroimaging abnormalities of PPD. This paper makes a literature investigation and summary on the brain imaging research of patients with PPD by multi-modal MRI technology, in order to help clinicians understand its progress.]]></description>
<pubDate>Sat,20 Nov 2021 00:00:00  GMT</pubDate>
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<title><![CDATA[Advances in neuroimaging studies of childhood autism]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2021.11.026</link>
<description><![CDATA[Autism is a widespread neurodevelopmental disorder in early childhood. Its incidence rate is increasing year by year and it causes children with lifelong mental disability and cannot take care of themselves, which brings heavy pressure to society and family. It is very important for the prognosis to take effective examination means to diagnose and intervene in the early stage of the disease. However, the early clinical symptoms of autism spectrum disorder (ASD) are not typical and the diagnosis is very difficult. With the development of neuroimaging, some studies have found abnormal changes in brain structure and function in children with ASD, which is particularly important for the early diagnosis and prognosis of clinical ASD.]]></description>
<pubDate>Sat,20 Nov 2021 00:00:00  GMT</pubDate>
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<title><![CDATA[Progresses of quantitative magnetic resonance imaging for myocardial tissue evaluation]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2021.11.027</link>
<description><![CDATA[Cardiomyopathy is a general term for a type of disease mainly composed of cardiomyopathy. It is often accompanied by cardiac dysfunction and severely endangers the lives of patients. In recent years, with the rapid development and advancement of cardiac magnetic resonance quantitative imaging technology, and due to its characteristics of no ionizing radiation and high resolution, it has a greater advantage in the evaluation of myocardial diseases. Among them, cardiac magnetic resonance quantitative imaging techniques such as longitudinal relaxation time quantitative imaging (T1 mapping), transverse relaxation time quantitative imaging (T2 mapping), T2* imaging quantitative imaging (T2* mapping), feature tracking (FT) and late gadolinium enhancement (LGE) can analyze myocardial tissue non-invasively and quantitatively, reflect the changes of myocardial tissue, and provide important quantitative information for the changes of different types of myocardial disease. The progresses of magnetic resonance quantitative imaging in evaluation of myocardial tissue were reviewed in this paper.]]></description>
<pubDate>Sat,20 Nov 2021 00:00:00  GMT</pubDate>
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<title><![CDATA[Research progress of MRI radiomics in cardiac diseases]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2021.11.028</link>
<description><![CDATA[Radiomics excavates, extracts and analyzes the textural features from standard medical images with high throughput to achieve quantitative analysis of heterogeneity of myocardium of different diseases, to improve the diagnostic accuracy of cardiac diseases, provide more accurate treatment plans and assess the prognosis of diseases. This review focuses on the research progress of MRI radiomics in cardiac diseases based on different sequences, including the sequences of cine magnetic resonance imaging (cine-MRI), native T1 mapping, T1 wighted imaging (T1WI), late gadolinium enhancement (LGE) and so on.]]></description>
<pubDate>Sat,20 Nov 2021 00:00:00  GMT</pubDate>
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<title><![CDATA[Advances of functional magnetic resonance imaging in quantitative diagnosis of liver fibrosis]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2021.11.029</link>
<description><![CDATA[Liver fibrosis is the common pathological basis for various chronic liver diseases to develop into cirrhosis. Early liver fibrosis can be reversed by clinical treatment. At present, the "gold standard" for the diagnosis and staging of liver fibrosis in clinical practice is liver biopsy, which is an invasive examination and carries certain risks. In recent years, functional magnetic resonance imaging technology has developed rapidly. As a non-invasive diagnosis method, it has played an important role in the field of quantitative detection and diagnosis of liver fibrosis. This article reviews the research progress of functional magnetic resonance imaging in the field of quantitative diagnosis of liver fibrosis.]]></description>
<pubDate>Sat,20 Nov 2021 00:00:00  GMT</pubDate>
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<title><![CDATA[Research progress of functional MRI in renal ischemia reperfusion injury]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2021.11.030</link>
<description><![CDATA[Renal ischemia reperfusion injury is an important cause of acute renal injury and reduced survival rate of renal allograft. Early detection of renal ischemia reperfusion injury is the key to ensure timely clinical intervention and treatment. With the development of magnetic resonance imaging technology, the application of functional magnetic resonance imaging (fMRI) in the diagnosis of renal diseases is gradually increasing, which can noninvasively and dynamically evaluate the changes of renal function from the aspects of water molecular diffusion, microcirculation, hemodynamics, oxygenation and so on. This article reviews the functional magnetic resonance imaging study of renal ischemia reperfusion injury in order to provide more methods and evidence for early clinical evaluation and noninvasive diagnosis.]]></description>
<pubDate>Sat,20 Nov 2021 00:00:00  GMT</pubDate>
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