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<title>Chinese Journal of Magnetic Resonance Imaging RSS feed</title>
<link>http://med-sci.cn/cgzcx/en/contents_list.asp?issue=201712</link>
<language>zh-cn</language>
<copyright>An RSS feed for Chinese Journal of Magnetic Resonance Imaging</copyright>
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<title><![CDATA[SWI and DKI study of brain iron deposition and microstructure change in gray matter nucleus in Parkinson<sup><sup>,</sup></sup>s disease]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2017.12.001</link>
<description><![CDATA[Objective: To explore the relationship between iron overload and microstructure change in the latter two levels, and further to compare and correlate the parameters from DKI and SWI in extrapyramidal systemic nuclei of Parkinson's disease (PD) patients and healthy controls. Materials and methods: This study was prospective and was approved by the hospital ethics committee. Thirty-five clinically confirmed PD patients and twenty-three healthy volunteers were enrolled in this study. PD group including 18 males and 17 females (mean age 67.00±8.76 years). Healthy control group (HC group) including 12 males and 11 females (mean age 66.48±5.2 years). All patients performed conventional MRI sequence, SWI sequence and DKI sequence scan. Bilateral Phase value, MD value, Da value, Dr value, MK value, Ka value, Kr value and FA value of the head of caudate nuclei, putamen, globus pallidus, thalamus, red nucleus, substantia nigra were measured. Two independent samples t-test was used to compare the phase value in all brain regions between the PD and HC groups. The correlations between SWI and DKI parameters of each nuclei of PD group were analyzed using Spearman correlation. All measurement data were shown as mean value and standard deviation. For all statistical analyses, a level of significance of P＜0.05. Results: The phase value decreased in substantia nigra, red nucleus, globus pallidus and the head of caudate nuclei while increased in putamen of patients with PD compared to the HC group (all P＜0.05). It showed positive correlation between the Phase value and Kr value in substantia nigra (r=0.349, P=0.030) and the Phase value and Da value in red nucleus (r=0.414, P=0.009); meanwhile, negative correlation between the Phase value and FA value in left putamen was found. Conclusions: The iron overload exists in every gray matter nucleus of the extrapyramidal system in PD patients. There are some relation between the iron overload and the change of microstructure in substantia nigra, red nucleus and putamen of patients with PD.]]></description>
<pubDate>Wed,20 Dec 2017 00:00:00  GMT</pubDate>
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<title><![CDATA[The value of the application of the SWAN and ASL in the blood vessels and thrombus of acute cerebral ischemic stroke]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2017.12.002</link>
<description><![CDATA[Objective:  To study the magnetic susceptibility weighted angiography (SWAN) and arterial spin labeling (ASL) on acute cerebral infarction responsible blood vessels and the clinical diagnostic value of blood clots. Materials and methods: Thirty patients with acute cerebral infarction due to severe stenosis or occlusion of the middle cerebral artery were collected from January 2015 to June 2017 in our hospital. Using conventional sequence of GE 3.0 T superconductive MRI scanner, MRA, SWAN and 3D-pCASL inspection, MRA, SWAN minimum density was obtained by post-processing software projection and ASL pseudo color map. Observed the blood vessels and blood clots. Results: In 30 cases of patients, SWAN prompted MCA responsible blood vessels and 25 cases of blood clots, CBF pseudo color map prompted middle cerebral artery M1 period of 23 cases of blood stasis or slow, two kinds of display method and MRA results have good consistency. Conclusions: SWAN combined with ASL showed significant clinical value in the indication of blood vessel site and blood clots components in acute cerebral ischemic stroke.]]></description>
<pubDate>Wed,20 Dec 2017 00:00:00  GMT</pubDate>
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<title><![CDATA[Analysis of metabolite levels in brain of preterm neonates by using multi-voxel magnetic resonance spectroscopy]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2017.12.003</link>
<description><![CDATA[Objective: To investigate the influence for metabolite levels in brain of preterm neonates who suffered perinatal asphyxia or perinatal infection by using multi-voxel magnetic resonance spectroscopy. Materials and methods: A total of 60 preterm neonates at term-equivalent age underwent MRI examination. The MRI examinations including multi-voxel 1H-MRS and other conventional plain sequences were performed using MAGNETOM Skyra (Siemens Healthcare, Erlangen, Germany), and 48 preterm infants were finally enrolled in this study and were divided into four groups: Group 1 (n=13, perinatal normal), Group 2 (n=10, perinatal asphyxia), Group 3 (n=12, perinatal infection) and Group 4 (n=13, perinatal asphyxia and infection). NAA/Cr, Cho/Cr, Lac/Cr ratios were collected from voxels located the basal ganglia and thalami (BGT) and periventricular white matter (WM), and all metabolic data were analyzed by SPSS 21.0 statistical software. Metabolic values were analyzed by t test in Group 1 and were analyzed by one-way ANOVA across 4 groups, if P＜0.05, q test for multiple comparisons were analyzed by SNK method. Results: ① The differences of both NAA/Cr and Cho/Cr between anterior periventricular white matter and posterior periventricular white matter were statistically significant in Group 1 (P＜0.001). ② In BGT region, the differences of all metabolic values including NAA/Cr, Cho/Cr and Lac/Cr were statistically significant between Group 1 and Group 2, between Group 1 and Group 4, between Group 2 and Group 3, between Group 3 and Group 4. ③ In region of WM, the differences of all metabolic values including NAA/Cr, Cho/Cr, Lac/Cr were statistically significant between Group 1 and Group 2, between Group 1 and Group 4, between Group 3 and Group 4; The difference of Cho/Cr was statistically significant between Group 1 and Group 3, between Group 2 and Group 4; The differences of both NAA/Cr and Lac/Cr were statistically significant between Group 2 and Group 3. Conclusions: ① The antero-posterior gradient of myelinization in periventricular white matter exist in preterm neonates, the development of myelinization is more maturer in posterior periventricular white matter. ② Perinatal asphyxia affects directly the process of myelination and disrupts neuronal and axonal integrity. ③ Perinatal infection only affects the process of myelination in periventricular white matter.]]></description>
<pubDate>Wed,20 Dec 2017 00:00:00  GMT</pubDate>
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<title><![CDATA[The comparison of sagittal full field-of-view and reduced field-of-view intravoxel incoherent motion imaging of spinal bone marrow]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2017.12.004</link>
<description><![CDATA[Objective: The purpose of this study is to compare image quality and the intravoxel incoherent motion (IVIM) parameters obtained with full FOV or reduced FOV IVIM imaging. Materials and Methods: Twenty-six healthy volunteers (12 male, 14 female) with age of 41.12±14.96 years (Mean±SD) were enrolled in this retrospective study. The lumbar imaging protocol included routine imaging, rFOV IVIM DWI (FOV 32 cm×12.8 cm, b=0 s/mm2, 15 s/mm2, 30 s/mm2, 50 s/mm2, 70 s/mm2, 100 s/mm2, 300 s/mm2, 500 s/mm2, 800 s/mm2 ) and fFOV IVIM DWI ( FOV 32 cm×32 cm, b=0 s/mm2, 15 s/mm2, 30 s/mm2, 50 s/mm2, 70 s/mm2, 100 s/mm2, 300 s/mm2, 500 s/mm2, 800 s/mm2). Raw rFOV and fFOV IVIM DWI data were post-processed by Functool provided in Advantage Workstation (version 4.6, GE), and each vertebral body was selected as a region of interest (ROI). Image quality of rFOV and fFOV IVIM DW images were qualitatively evaluated by using a 5-point likert scale. IVIM DWI distortion was quantitatively evaluated by calculating the distortion rate of L3 vertebral body. The quantitative measurements and qualitative scores of IVIM DW images were performed by two radiologists who were blinded to the clinical and sequences information, and the consistency of the two readers was evaluated, and the mean IVIM parameters, qualitative scores, and distortion ratios of the two readers were calculated. The IVIM parameters (ADCfast, ADCslow, f), qualitative scores, and distortion ratios of the two IVIM DWI were compared with paired t-test or Wilcoxon's test according to the Kolmogorov-Smirnov test. Results: In this study, there was good inter reader agreement in IVIM parameters, qualitative scores and distortion rate of rFOV-IVIM DWI and fFOV IVIM DWI. Statistically significant differences in ADCfast (t=-9.92, P＜0.01) , ADCslow (Z=-2.20, P＜0.05), f (t=-17.86, P＜0.01), image quality scores (Z=-12.76, P＜0.01), area distortion rate (Z=-4.27, P＜0.01), and anteroposterior distances distortion rate (Z=-6.20, P＜0.01) between rFOV and fFOV IVIM DWI was observed, while no significant difference in craniocaudal distances distortion rate (t=-0.50, P=0.62) between rFOV and fFOV IVIM DWI was observed. Conclusions: Compared with fFOV IVIM, rFOV IVIM DW images of spine bone marrow show improved image quality, and rFOV IVIM technique of spine may help to obtain relatively accurate IVIM parameters.]]></description>
<pubDate>Wed,20 Dec 2017 00:00:00  GMT</pubDate>
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<title><![CDATA[The application of magnetic resonance imaging in the diagnosis of brucellosis spondylitis]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2017.12.005</link>
<description><![CDATA[Objective: To investigate the MRI findings of brucellosis spondylitis, so as to improve the level of diagnosis and differential diagnosis of brucellosis spondylitis. Materials and methods: The MRI images of 65 patients with brucellosis spondylitis confirmed by clinical were analyzed retrospectively from January 2015 to April 2017. Predilection site of disease, shape and signal characteristics of the vertebral body, characteristics of each sequence signal and the situation of surrounding tissue were analyzed. Results: Brucellosis spondylitis was common on the lumbar spine, and the lesions were located in the anterior and middle part of the vertebral body. The morphological changes of the diseased vertebral body were not obvious in 41 cases, T1WI showed imaging is low signal, T2WI showed high or low signal, the SPAIR sequence showed high signal intensity, and obviously enhanced in the enhanced scan. Intervertebral space narrowed in 53 cases. There were 58 cases of extra vertebral soft tissue were involved, paravertebral abscess in 58 cases, epidural abscess in 18 cases, the signal of abscess was inhomogeneous in long T1 and long T2. SPAIR sequence showed mixed high signals with blurred boundaries, it contains some abscess cavity, which is multiple sizes, uneven thickness wall and obvious enhanced. 28 patients had accompanying signs, including small vertebral joint inflammation, anterior longitudinal ligament and interspinous ligament calcification. Conclusions: MRI manifestations of brucellosis spondylitis are characteristic, MRI has important value in diagnosis and differential diagnosis of brucellosis spondylitis, the SPAIR sequence can remove the interference of fat tissue, can sensitively detect lesions and is of great significance to show the lesion and the surrounding circumstances.]]></description>
<pubDate>Wed,20 Dec 2017 00:00:00  GMT</pubDate>
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<title><![CDATA[The value of dynamic contrast-enhanced magnetic resonance imaging in the staging of brucellosis spondylitis]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2017.12.006</link>
<description><![CDATA[Objective: To quantitatively analyze brucellar spondylitis (BS) by applying dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI), and to evaluate the value of quantitative DCE-MRI in the stating of BS. Materials and methods: Analyzed 28 BS patients with complete biochemical detection or operation data (17 males and 11 females; mean age 52 years old). All patients received routine MRI and DCE-MRI examinations. Volume transfer constant (Ktrans), rate constant (Kep), extravascular extracellular volume fraction (Ve) and plasma volume fraction (Vp) of diseased vertebral bodies of the patients were measured in perfusion parameter maps. The four parameters were compared among the diseased vertebres and the non-diseased vertebres, Ktrans, Kep were compared the acute group and the non-acute group by t-test. Results: Ktrans, Kep, Ve and Vp showed statistically significant differences (P＜0.05) between the diseased vertebrae and the non-diseased vertebrae. Ktrans was 1.723±0.266, Kep was 2.177±0.690 in the acute group, Ktrans was 2.177±0.690, Kep was 1.508±0.877 in the non-acute group, it showed statistically significant differences (P＜0.05). Conclusions: DCE-MRI quantitative analysis has great value in the diagnosis and staging of BS.]]></description>
<pubDate>Wed,20 Dec 2017 00:00:00  GMT</pubDate>
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<title><![CDATA[Application of intravoxel incoherent motion imaging of 3.0 T magnetic resonance imaging on the identification rectal tubulovillous adenoma and rectal cancer]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2017.12.007</link>
<description><![CDATA[Objective:  To evaluate the role of differential diagnosis of 3.0 T intravoxel incoherent motion magnetic resonance imaging (IVIM-MRI) on rectal tubulovillous adenoma and rectal cancer. Materials and methods: 11 cases of rectal tubulovillous adenoma and 30 cases of rectal cancer patients (confirmed by pathology) were enrolled in this study between June 2016 and June 2017 at the First Affiliated Hospital of Soochow University 3.0 T MRI normal sequences and IVIM examination in the two groups before surgery. Perfusion-related diffusion coefficient (D), real diffusion coefficient (D*), perfusion fraction (f) and apparent diffusion coefficient (ADC) were measured on the post-processing software, and D, D*, f and ADC values were compared respectively to analyze the diagnosis efficiency of each parameter of rectal tubulovillous adenoma and rectal cancer. Results: The D value and standard ADC value of rectal cancer group were lower than those of rectal tubulovillous adenoma group, and the difference was statistically significant (all P＜0.05). The mean value of D* was higher than that of rectal tubulovillous adenoma group, but the difference was not statistically significant (P＞0.05). There was no significant difference between the two groups (P＞0.05). The cut-off value for rectal tubulovillous adenoma and rectal cancer was ADC＜1.026×10-3 mm2/s, the sensitivity and specificity was 81.8%, 70%; D＜0.788×10-3 mm2/s, the sensitivity and specificity was 87.9%, 71.1%. Conclusions: D and ADC value have reference value for identification of diagnosis of rectal cancer and rectal tubulovillous adenoma.]]></description>
<pubDate>Wed,20 Dec 2017 00:00:00  GMT</pubDate>
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<title><![CDATA[Liver ESWAN and serum ferritin for quantitative evaluation of liver fibrosis: An experimental study]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2017.12.008</link>
<description><![CDATA[Objective: To investigate whether the value of T2* and magnitude images of ESWAN (enhanced T2* weight angiography) and the serum ferritin could determine liver fibrosis and evaluate the liver fibrosis stage. Materials and Methods: Sixty four new zealand white rabbits in this study, eight rabbits were as normal control group and fifty six rabbits were used to model liver fibrosis with CCL4 by intraperitoneal injection. The rabbits underwent MRI scan on 6th, 8th, 10th and 12th week after beginning of modeling the liver fibrosis. The values of T2* and magnitude images were obtained and got the liver METAVIR stage, and acquired the value of serum ferritin by ELISA. Results: The values of T2* and magnitude were decreased with increasing stage of fibrosis (r=-0.588, -0.388 respectively; all P＜0.05) while the value of serum ferritin was increased (r=0.409, P＜0.05). The value of T2* could distinguish normal group from F2, F3 and F4 respectively, F1 from F4, F1 from F2-4 (all P＜0.05), and the AUC≥0.74. The value of magnitude imagine could distinguish the normal group from F4, F1 from F4 and F1-3 from F4 (all P＜0.05), and the AUC≥0.822. The value of serum ferritin could differentiate normal group from F3, F4 respectively (all P＜0.05), and the AUC≥0.873. Conclusions: The value of T2* and magnitude and serum ferritin could quantificationally determine the presence and the severity of fibrosis.]]></description>
<pubDate>Wed,20 Dec 2017 00:00:00  GMT</pubDate>
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<title><![CDATA[The application of different NEX amide proton transfer imaging in brain tumors on 1.5 T MRI scanner]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2017.12.009</link>
<description><![CDATA[Objective: To analyze the effects of different number of excitation (NEX) amide proton transfer imaging in brain tumors on 1.5 T MRI scanner. Materials and Methods: The data acquisitions were carried out in clinical cases using GE Signa HDe 1.5 T MRI. The data were collected and analyzed on the analysis of the different NEX, such as the original signal, APT signal. Results: In the comparative analysis group, NEX=2 and 8, the original image quality scores were 4.55±0.83, 4.60±0.68, respectively, and there was no statistical difference; The image quality scores of the APT image were 2.7±1.03, 3.35±0.81 respectively, a statistically significant difference. The sensitivity of original image is 100%, and the sensitivity of APT image is 70% and 90%, respectively. In the random packet analysis group, NEX=2 and 8, the original image quality scores were 4.54±0.78, 4.69±0.63, respectively, and there was no statistical difference; The image quality score APT image were 2.89±0.96, 3.60±0.69, a statistically significant difference. The sensitivity of original image is 100%, and the sensitivity of APT image is 77.1% and 94.3%, respectively. No matter what a group of results, all APT images are down a file than the original images. The APT images signal to noise ratio (SNR) is relatively low, but can display and distinguish lesions. Conclusions: APT imaging after optimizing parameters, the distribution of lesions can clearly distinguish brain tumors, brain tumors and other biological metabolites presenting information from the level of molecular imaging studies, the scope of early diagnosis and evaluation of tumor and its relationship with the surrounding anatomical structure, has important significance to tumor prognosis and treatment. If the subject is unable to tolerate, the APT image of NEX=2 can also provide relatively satisfactory APT imaging results.]]></description>
<pubDate>Wed,20 Dec 2017 00:00:00  GMT</pubDate>
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<title><![CDATA[Application and development of arterial spin labeling technique of magnetic resonance imaging in cerebrovascular disease]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2017.12.012</link>
<description><![CDATA[Arterial spin labeling (ASL) is a functional MRI technique that can noninvasively assess cerebral blood flow using blood as an endogenous contrast agent. In this article, the clinical application of ASL technology in cerebrovascular disease will be reviewed. In transient ischemic attack, ASL can be sensitive to the brain perfusion abnormalities. In acute cerebral infarction, ASL can be used to assess ischemic penumbra, identify arterial occlusion of the arteries, and detect high perfusion around the infarct area. In the chronic cerebrovascular disease, multi-ASL technique can assess cerebral blood flow more accurately than before; two-stage ASL technology can assess collateral blood vessels quantitatively, also ASL can be used to assess cerebrovascular reserve. In moyamoya disease, ASL technology can assess the preoperative and postoperative perfusion and collateral blood vessels. The final statement is about ASL technology in cerebrovascular malformations and reversible posterior encephalopathy application. In the final part, current limitations and future developments of ASL techniques will be reviewed.]]></description>
<pubDate>Wed,20 Dec 2017 00:00:00  GMT</pubDate>
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<title><![CDATA[Research progress of functional MRI in irritable bowel syndrome]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2017.12.013</link>
<description><![CDATA[The mechanism of irritable bowel syndrome (IBS) may be related to such factors as visceral hypersensitivity, abnormal intestinal motility, inflammation, psychological factors and so on. However, the symptoms of the disease could explain the lack of morphological changes and biochemical abnormalities. The etiology and pathogenesis of the disease are still unclear. The role of the "brain gut axis" in the pathogenesis of IBS has attracted wide attention and has become a breakthrough point in the study of IBS pathogenesis. Functional magnetic resonance imaging (fMRI) is a noninvasive method detecting neural activity, and has the ability to observe the brain tissue microstructure and functional changes in vivo. FMRI provides a new angle of view for evaluating the central mechanism of "brain gut axis", and also can display the activity of brain and changes in the nerve pathways in IBS patients. In addition, it also has important significance to evaluate the therapeutic effect. This article reviews the present research situation and progress of fMRI in IBS diagnosis and its therapeutic efficacy.]]></description>
<pubDate>Wed,20 Dec 2017 00:00:00  GMT</pubDate>
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<title><![CDATA[Progress of diffusion tensor imaging in acute spinal cord injury]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2017.12.014</link>
<description><![CDATA[The spinal cord is an important component of the central nervous system. The consequences caused by spinal cord injury and prognosis in different periods and different degrees are different. The development of acute spinal cord injury is rapid and serious. The conventional magnetic resonance imaging signal change has certain limitations for clinical evaluation. The magnetic resonance diffusion weighted and diffusion tensor imaging reflect the damage of spinal cord by microscopic reflection of the dispersion of water molecules. It can not only judge the acute spinal cord injury in early and timely, but also quantitatively analyze the severity of white matter fiber damage, It can provide some information about the value of this kind of patient's intervention for clinical. In this paper, the application and progress of MR diffusion weighted imaging and magnetic resonance diffusion tensor imaging in acute spinal cord injury were reviewed.]]></description>
<pubDate>Wed,20 Dec 2017 00:00:00  GMT</pubDate>
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<title><![CDATA[The application of magnetic resonance imaging in evaluating efficacy of neoadjuvant chemotherapy for breast cancer]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2017.12.015</link>
<description><![CDATA[With its advantage of high sensitivity and accuracy, magnetic resonance imaging (MRI) has been the most compelling imaging test in evaluating the efficacy of neoadjuvant chemotherapy (NAC) of breast cancer and widely accepted by the clinic. However, due to the high heterogeneity and the various shrinking patterns after chemotherapy, the current MRI assessment regimens could not help clinicians to formulate therapy plan individually. Therefore, it has become a close concern for how MRI to evaluate the efficacy of NAC accurately. Reviewing of the application of MRI in different phase of neoadjuvant chemotherapy, we will discuss the appropriate MRI testing times and imaging index and then look forward to future directions in this area based on tumor heterogeneity.]]></description>
<pubDate>Wed,20 Dec 2017 00:00:00  GMT</pubDate>
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<title><![CDATA[Analysis of magnetic resonance imaging quality control in bone and joint system]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2017.12.016</link>
<description><![CDATA[Magnetic resonance diagnosis of bone and joint system diseases has been recognized, especially for the joints, can be very clear and accurate display of its anatomical structure, and even with a fixed dissection of specimens comparable. With the MRI in the field of bone and joint diagnosis of a wide range of applications, how to further improve the scanning method to innovation, how to improve its diagnostic criteria has become an important issue of medical staff. In magnetic resonance imaging, there are many factors that affect the image quality, including the subject position, sampling orientation, imaging parameters and sequence setting principles, common artifacts and treatment principles, and so on. The rational control or application of these factors will help to establish a practicable uniform quality control standard for the osteoarticular system, and play a decisive role in the optimization of magnetic resonance technology and the acquisition of high quality images.]]></description>
<pubDate>Wed,20 Dec 2017 00:00:00  GMT</pubDate>
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