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<title>Chinese Journal of Magnetic Resonance Imaging RSS feed</title>
<link>http://med-sci.cn/cgzcx/en/contents_list.asp?issue=202012</link>
<language>zh-cn</language>
<copyright>An RSS feed for Chinese Journal of Magnetic Resonance Imaging</copyright>
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<title><![CDATA[The interpretation of the 2020 publication of the Society for Cardiovascular Magnetic Resonance (SCMR) on standardized cardiovascular magnetic resonance imaging (CMR) protocols]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2020.12.001</link>
<description><![CDATA[“Standardized cardiovascular magnetic resonance imaging protocols: 2020” by Christopher M. Kramer, et al. was published online on 24 February 2020 in Journal of Cardiovascular Magnetic Resonance. This document is an update to the 2013 publication of the Society for Cardiovascular Magnetic Resonance (SCMR) on Standardized Protocols. It added more technical criteria and introduced imaging requirements in patients with devices in day-to-day clinical practice. On the basis of this protocol, this paper comprehensively interprets the technical criteria of cardiac magnetic resonance imaging in combination with China's national conditions, and provides a reference for cardiac magnetic resonance imaging in China.]]></description>
<pubDate>Sun,20 Dec 2020 00:00:00  GMT</pubDate>
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<title><![CDATA[Interpretation of the new WHO classification of bone tumors (2020)]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2020.12.002</link>
<description><![CDATA[There are certain changes in the classification of bone tumors in the fifth edition of the WHO Bone and Soft Tissue Tumors fascicle issued in 2020. We briefly summarize the main changes in this part as the adjustment of the overall classification of bone tumor in the new version, the classification and naming of each bone tumor, the new/deleted lesions, the reclassified lesions and the redefinition of known tumors, etc. Also, it is compared with the 4th edition issued in 2013 to help readers understand the content of the new classification faster and guide clinical diagnosis and treatment.]]></description>
<pubDate>Sun,20 Dec 2020 00:00:00  GMT</pubDate>
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<title><![CDATA[The value of apparent diffusion coefficient histogram in distinguishing ependymoma from anaplastic ependymoma]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2020.12.003</link>
<description><![CDATA[Objective: To explore the value of apparent diffusion coefficient histogram in distinguishing ependymoma from anaplastic ependymoma. Materials and Methods: The information of 20 patients with intracranial ependymoma and 14 patients with anaplastic ependymoma before operation were collected retrospectively. Based on the patients' apparent diffusion coefficient images, the boundaries of tumor were delineated layer by layer as the region of interest to construct the whole lesion, and the histogram analysis of the constructed region was carried out by Mazda software. The differences between the histogram parameters of ependymoma and anaplastic ependymoma were compared, and draw the operating characteristic curve of the subjects to evaluate the diagnostic performance of relevant parameters. Results: The histogram indicators with significant differences between ependymoma and anaplastic ependymoma were: mean value (P=0.010, area under the curve=0.78), kurtosis (P=0.034, area under the curve=0.75) , 99th percentile (P=0.008, area under the curve=0.76).The parameters with no significant difference between the two groups were variance, skewness and the 1st, 10th, 50th and 90th percentile (P＞0.05). When the average value, kurtosis and the 99th percentile were combined for diagnosis (area under the curve=0.89, sensitivity=85.0%, specificity=85.7%), the overall diagnostic efficiency was significantly improved. Conclusions: Histogram analysis of apparent diffusion coefficient has application value in distinguishing ependymoma from anaplastic ependymoma, especially the multi-parameter combined diagnosis is more valuable.]]></description>
<pubDate>Sun,20 Dec 2020 00:00:00  GMT</pubDate>
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<title><![CDATA[Application of 3.0 T MRI 2D-CSI 1H-MRS in children with temporal lobe epilepsy without morphological changes]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2020.12.004</link>
<description><![CDATA[Objective: To explore the value of two-dimensional chemical shift magnetic resonance imaging of hydrogen proton spectroscopy (2D-CSI 1H-MRS) in the micro changes of hippocampus. Materials and Methods: The spectral data of temporal lobe hippocampus in 36 cases of children and 20 cases of healthy control group were retrospectively analyzed to observe the relationship between gender, age and distribution, and to analyze the metabolic information of MRS in unilateral, bilateral and control groups of observation group and unilateral and healthy side of observation group. Results: There were 36 cases with male and left temporal lobe, but there was no significant difference in gender and location distribution (χ2=1.67, P＞0.05); the age of onset of bilateral males in the observation group was younger than that of females (F=12.25, P=0.015). NAA/Cr, NAA/Cho, NAA/(Cho+Cr) in the observation group were significantly lower than those in the control group (F=12.22, 35.786, 6.712; P＜0.001), Cho/Cr increased in unilateral group (F=14.712, P＜0.001), the differences were statistically significant (P＜0.05); compared with the uninjured side, NAA decreased and Cho increased in the observation group (P=0.034, 0.016), and the differences were statistically significant (P＜0.05). Conclusions: 2D-CSI 1H-MRS examination showed that there were microscopic abnormalities and changes in cellular and molecular levels in temporal lobe. Therefore, it is a promising tool for the evaluation of TLE in children.]]></description>
<pubDate>Sun,20 Dec 2020 00:00:00  GMT</pubDate>
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<title><![CDATA[Correlation research between FLAIR vascular hyperintensities and cerebral infarction in short term after transient ischemic attack of the internal carotid artery]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2020.12.005</link>
<description><![CDATA[Objective: To probe the relationship between fluid-attenuated inversion recovery vascular hyperintensities (FVH) and short-term cerebral infarction ocurrence in patients with transient ischemic attack (TIA) of the internal carotid artery. Materials and Methods: Retrospective analysis of MRI and clinical data in total 168 lesion-negative TIA patients with follow-up MRI examination during January 2010 to March 2019 in our hospital was executed, and then the multi-factor regression analysis was used to analyze whether FVH, internal carotid atherosclerosis (ICAS), etc. were the risk factors for the short-term cerebral infarction ocurrence in TIA patients. Results: Among eligible 168 TIA patients, 30 patients (17.86%) had unilateral FVH, 45 patients (26.79%) had DWI lesion on the follow-up MRI examination. According to the DWI lesion observed or not, these patients were thereby divided into two groups: R-DWI [+] group and R-DWI [-] group. In the multivariate analysis, both FVH (aOR=0.079, 95% CI=0.020–0.310, P＜0.001) and ICAS (aOR=0.257, 95% CI=0.082—0.810, P＜0.05) showed as an independent predictor of R-DWI [+]. Even though adjusted by FVH×ICAS (used to eliminate the interaction between FVH and ICAS), FVH was still associated with R-DWI [+]. Conclusions: FVH is the risk factor for short-term cerebral infarction ocurrence in TIA patients.]]></description>
<pubDate>Sun,20 Dec 2020 00:00:00  GMT</pubDate>
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<title><![CDATA[Study on brain structure network of patients with delayed encephalopathy after carbon monoxide poisoning: Based on diffusion tensor imaging]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2020.12.006</link>
<description><![CDATA[Objective: Diffusion tensor imaging (DTI) was used to measure the changes in brain structural networks of delayed encephalopathy after acute carbon monoxide poisoning (DEACMP) patients, and to explore the neuroimaging mechanism of DEACMP cognitive disorder. Materials and Methods: DTI scans were performed on 25 DEACMP patients and 25 Healthy Controls (HCs) matched by age and gender. The AAL template was used to divide the whole brain into 90 regions. The continuous tracer method was used to reconstruct the brain fiber bundle connection network and the brain structure-weighted network. The global and regional properties were computed by graph theoretical analysis. To compare the brain network regional properties between two groups, two-sample t-test (false discovery rate correction, P＜0.05) was utilized. The correlations between the brain structural network properties and clinical parameters were further analysed. Results: Both of the two groups were found to follow the efficient small-world characteristics. The shortest path length of the DEACMP group increased (Lp=0.86±0.05), global efficiency (Eglob=9.60±2.65) and local efficiency (Eloc=17.98±3.89) decreased. Moreover, the core nodes of the DEACMP group's default network, highlighting network, central execution network, and visual area were reduced (P＜0.05, FDR correction). The left amygdala node degree of DEACMP group was positively correlated with MMSE and MoCA (r=0.863, P=0.001; r=0.525, P=0.021); the left tongue gyrus degree value was positively correlated with MoCA (r=0.406, P=0.019), and CDR negative correlation (r=-0.563, P=0.016). The efficiency value of the right dorsolateral superior frontal gyrus node in the DEACMP group was negatively correlated with the CDR score (r=-0.377, P=0.031). Conclusions: The difference of topology attributes and nodes in DEACMP patients can show the degree of damage to related brain regions, especially to advanced brain functions, in DEACMP patients.]]></description>
<pubDate>Sun,20 Dec 2020 00:00:00  GMT</pubDate>
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<title><![CDATA[The value of 3.0 T MR IVIM and DKI in evaluating benign and malignant breast lesions]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2020.12.007</link>
<description><![CDATA[Objective: To evaluate the independent and combined diagnostic efficacy of 3.0 T MR intravoxel incoherent motion (IVIM) and diffusion kurtosis imaging (DKI) for benign and malignant breast lesions. Materials and Methods: Prospective collection of 50 female breast lesions (54 lesions in total) who underwent preoperative multi-parameter MR functional imaging and obtained definite pathological results. The diffusion coefficient (D), pseudo-diffusivity coefficient (D*), perfusion fraction (f) and mean diffusion kurtosis coefficient (MK), mean diffusion coefficient (MD) were obtained by using MITK and DKE software. The statistical differences of each parameter were analyzed and ROC curve was used to evaluate the diagnostic efficacy of the parameters with significant differences. Results: There were statistically significant differences between malignant and benign lesions in parameters of D, f, MK and MD values (P＜0.05), while there was no significant difference in D* value (P＞0.05). Using pathological results as the gold standard , the AUC of D, f, MK and MD values diagnosis of breast benign and malignant lesions were 0.927, 0.664, 0.944 and 0.876, respectively. Using 0.91×10-3 mm2/s, 14.58%, 0.75 and 1.47×10-3 mm2/s as the cut-off of the four parameters, the sensitivity and specificity of differentiating malignant and benign lesions were (90.91%, 95.24%), (57.58%, 76.19%), (87.88%, 85.71%) and (81.82%, 80.95%), respectively. Conclusions: The MK value in IVIM and DKI parameters has larger AUC, while the D value has high sensitivity and specificity. The AUC and sensitivity of D+MK were the highest in the combined diagnosis. IVIM and DKI have clinical value in the differential diagnosis of breast benign and malignant diseases, and the combined application can improve the diagnostic efficiency.]]></description>
<pubDate>Sun,20 Dec 2020 00:00:00  GMT</pubDate>
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<title><![CDATA[The value of routine MRI combined with diffusion-weighted imaging in the differential diagnosis of atypical liver abscess and intrahepatic cholangiocarcinoma]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2020.12.008</link>
<description><![CDATA[Objective: To investigate the value of MR routine examination combined with diffusion-weighted imaging (DWI) in the differentiation of atypical liver abscess and intrahepatic cholangiocarcinoma (ICC). Materials and Methods: MR images of 19 cases of ICC and 19 cases of atypical liver abscess were retrospectively identified, observing the difference in MR signs of the lesion, the mean apparent diffusion coefficient value (ADCmean) and the relative apparent diffusion coefficient value (rADC) of the solid part of the lesion edge between the two groups. Differences in MR signs and ADC values between the two groups were evaluated with the t test and χ2 test. Results: ICC and atypical liver abscess showed statistically significant differences in arterial phase broken ring sign, hepatic perfusion disorders, and hepatic capsular retraction (P＜0.05). The ADCmean value and rADC value of the solid components at the edge of the ICC lesion were (0.84±0.14)×10-3 mm2/s and (0.70±0.12), respectively; the ADCmean value and rADC value of the solid components at the edge of the liver abscess were (1.04±0.10)×10-3 mm2/s and (0.95±0.05), respectively; the difference between the two groups was statistically significant (P＜0.001). The area under the ROC curve of ADCmean value and rADC value were 0.832 and 0.964, respectively. Taking 0.86×10-3 mm2/s as the cut-off value, the sensitivity and specificity of ADCmean value in distinguishing ICC from atypical liver abscess are 100% and 63.2%, respectively. Taking 0.83 as the cutoff value, the sensitivity and specificity of rADC to distinguish between the two are 100% and 84.2%, respectively. Conclusions: MR routine examination combined with DWI can help to distinguish ICC from atypical hepatic abscess.]]></description>
<pubDate>Sun,20 Dec 2020 00:00:00  GMT</pubDate>
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<title><![CDATA[The feasibility of semi-automatic segmentation technology for quantification of pancreatic fat: Comparative study with traditional ROI methods]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2020.12.009</link>
<description><![CDATA[Objective: To explore the feasibility of quantifying pancreatic fat fraction (PFF) with semi-automatic segmentation using 3D mDixon Quant sequence. Materials and Methods: Thirty healthy subjects who underwent upper abdomen 3.0 T MR (Ingenia CX, Philips) including 3D mDixon Quant sequences were collected. There were 14 males and 16 females, age range 22—69 years (median age, 48 years), body mass index (BMI) range 17.71—32.59 kg/m2 (median, 24.57 kg/m2). After scanning, the images were imported into ISP (IntelliSpace Portal, Philips) workstation. Traditional regions of interest (ROI) placement and semi-automatic segmentation techniques were used to measure PFF on fat fraction images. Three ROIs were placed on the pancreatic uncinate process, head and neck, body, and tail, avoiding blood vessels, pancreatic duct and visceral adipose tissue. The mean value of ROIs was recorded as the FF in this region, and then the average FF of all regions were calculated as the whole PFF. Pancreatic tissue was manually traced on fat fraction images and was semi-automatically segmented, and then whole PFF was calculated automatically. The operation time was recorded. Two observers (3 and 5 years of imaging diagnosis experience) used two methods to measure PFF. Data were analyzed by SPSS 22.0. Shapiro-Wilk test was used to test the normality of the data. The intra-class correlation coefficient (ICC) was used to test the consistency of the data. The non-parametric Mann-Whitney U test was used to test the differences in PFF and the operation time by the two methods. Results: The data consistency of two observers was good (ICC=0.981, 0.929). The consistency of whole PFF in two groups was good (ICC=0.981). The whole PFF (%) of the two groups were 3.73 (2.97, 5.84) and 4.20 (3.05, 6.21) respectively. The semi-automatic segmentation technique measured the pancreatic fat fraction slightly larger than the traditional ROI placement method, and there was no significant difference (Z=-0.466, P＞0.05). The operation time was statistically different (85 s vs 133 s, Z=-6.238, P＜0.05). Conclusions: The semi-automatic segmentation technology is feasible for the quantification of pancreatic fat. It can significantly shorten the measurement time under the condition of ensuring the accuracy of the results, and has a good clinical application prospect.]]></description>
<pubDate>Sun,20 Dec 2020 00:00:00  GMT</pubDate>
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<title><![CDATA[MRI features of the submandibular gland in Sjögren syndrome]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2020.12.010</link>
<description><![CDATA[Objective: To investigate the MRI imaging features and diagnostic efficacy of submandibular glands in patients with Sjögren's syndrome (SS). Materials and Methods: MRI images of the submandibular glands of 31 patients diagnosed with SS and 15 healthy volunteers were collected. Observed T1WI, T2WI and lipid-suppressing T2WI images, and classified the fat signal of the submandibular glands of the patients. Measured the volume of the bilateral submandibular glands of the subject and observed the volume changes of the two groups. Results: All patients showed uneven changes in bilateral submandibular gland signals. Both T1WI and T2WI images showed multiple diffuse fat signals, and lipid-suppressed T2WI showed low signals. Of the 62 glands, 50 lesions were detected by conventional MRI, with no false positive results. There are 12 at grade 0, 14 at grade 1, 10 at grade 2, 13 at grade 3, and 13 at grade 4. There were no fat signals in 30 submandibular glands in 15 cases in the control group, and the fat signal grade was 0. The sensitivity of the submandibular gland was 80.7%, and the positive predictive value was 100%, specificity is 100%. The AUC of submandibular gland fat signal classification is 0.903. The volume of the submandibular gland in the case group was less than that of the control group (P＜0.05), and the volume of the non-grade submandibular gland in the case group was less than that of grade 0 (P＜0.05). The correlation between the volume of submandibular glands and the classification of fat signals in the case group was poor (r=-0.102, P＞0.05), and the results were not statistically significant. Conclusions: Routine submandibular gland MRI examination can be used as one of the imaging examinations to diagnose SS.]]></description>
<pubDate>Sun,20 Dec 2020 00:00:00  GMT</pubDate>
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<title><![CDATA[Predictive value of random forest based on MRI radiomics in evaluating the invasion depth of endometrial carcinoma]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2020.12.011</link>
<description><![CDATA[Objective: To explore the predictive value of random forest based on MRI plain T2WI and contrast-enhanced T1WI radiomics in evaluating the invasion depth of endometrial carcinoma. Materials and Methods: We retrospectively analyzed one hundred and fourteen (eighty-six cases of stage ⅠA and twenty-eight cases of stage ⅠB) patients with endometrial carcinoma confirmed by surgical pathology and all patients underwent pelvic MRI plain and contrast-enhanced examination. All MRI data were divided into training and testing set by stratified sampling method with the ratio of 4∶1. The ITK-SNAP software was used to manually delineate the region of interest layer by layer on the sagittal T2WI images and the second phase of the multi-phase T1WI contrast-enhanced images. The radiomics features were extracted based on an open soured tool named pyradiomics (https://github.com/Radiomics/pyradiomics), and the model was established based on scikit-learn (https://www.sklearn.org/). Predictive performance was evaluated by the receiver operating characteristics (ROC) curve. Results: In the testing set, the area under the curve (AUC) of the RF model based on the plain T2WI images predicting the depth of myometrial invasion for endometrial carcinoma was 0.938, and the accuracy, sensitivity and specificity were 91.3%, 87.5%, and 93.3%, respectively. The top three most important features of the model were shape flatness, GLSZM zone variance, and GLRLM run variance; The AUC of the RF model based on contrast-enhanced T1WI images was 0.818, the accuracy, sensitivity and specificity were 81.8%, 100%, and 75.0%, respectively. The top three most important features of the model were shape flatness, GLDM large dependence high gray level emphasis, and GLCM correlation. Conclusions: The algorithm of random forest based on MRI radiomics demonstrated great potential in predicting the invasion depth of endometrial carcinoma, and the model based on T2WI images demonstrated more diagnostic value than that contrast-enhanced T1WI images.]]></description>
<pubDate>Sun,20 Dec 2020 00:00:00  GMT</pubDate>
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<title><![CDATA[A Meta analysis of quantitative evaluation of lumbar disc degeneration by diffusion weighted magnetic resonance imaging]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2020.12.012</link>
<description><![CDATA[Objective: Based on Meta analysis to explore the clinical application of magnetic resonance diffusion weighted imaging in quantitative evaluation of early lumbar disc degeneration. Materials and Methods: Literature on evaluation of lumbar disc degeneration using diffusion weighted imaging (DWI) published in PubMed, EMBASE, the Cochrane Library, CNKI, Wanfang and VIPS databases from the self-built database to October 1, 2019 was retrieved. Two researchers independently screened and extracted the retrieved literature according to inclusion and exclusion criteria. Combie cross study evaluation tool was used to evaluate the quality of the included literature. Using RevMan 5.3 and Stata 15.0 software for Meta analysis. Results: A total of 12 references were included. There were 577 grade Ⅰ discs, 1704 grade Ⅱ discs, 1299 grade Ⅲ discs, 1092 grade Ⅳ discs and 194 grade Ⅴ discs. ADC value of grade Ⅰ discs nucleus pulposus was higher than that of grade Ⅱ discs nucleus pulposus. The difference was statistically significant weighted mean difference (WMD)=0.034, 95% CI: 0.005—0.064, P=0.024. ADC value of grade Ⅱ discs nucleus pulposus was significantly higher than that of grade Ⅲ discs nucleus pulposus (WMD=0.161, 95% CI: 0.124—0.197, P＜0.0001). ADC value of grade Ⅲ discs nucleus pulposus was significantly higher than that of grade Ⅳ discs nucleus pulposus (WMD=0.297, 95% CI: 0.222—0.373, P＜0.0001). ADC value of grade Ⅳ discs nucleus pulposus was significantly higher than that of grade Ⅴ discs nucleus pulposus (WMD=0.293, 95% CI: 0.176—0.411, P＜0.0001). Conclusions: Diffusional weighted imaging can quantitatively evaluate different grades of lumbar disc degeneration, especially distinguish early lumbar disc degeneration, and provide imaging basis for early diagnosis of lumbar disc degeneration.]]></description>
<pubDate>Sun,20 Dec 2020 00:00:00  GMT</pubDate>
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<title><![CDATA[MRI findings of whole spinal in 22 patients with SAPHO syndrome]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2020.12.013</link>
<description><![CDATA[Objective: To evaluate MRI manifestations of the whole spinal lesions of synovitis, acne, palmoplantar pustulosis, hyperostosis and osteitis (SAPHO) syndrome and investigate its regularity. Materials and Methods: The distribution, involvement patterns, and characteristics of both active inflammatory and chronic structural lesions of the whole spine 3.0 T MRI images of 22 SAPHO syndrome patients were analyzed. Auto-tracking-bedscanning technic was applied to scan the cervical, thoracic, and lumbar part and the image was stitched by whole spine imaging software. Results: SAPHO syndrome involvement spinal lesions were mainly located in the thoracic segments (45.4% of spinal lesions) (P＜0.05). Bone marrow edema (BME) was the most common active lesion, and lipid deposition was the most common structural lesion, which were mainly distributed at the anterior corners of thoracic vertebra. The jump distribution and parallel distribution were 53.3% and 46.7% of BME, 41.3% and 58.7% of lipid deposition, respectively. Other lesions included bone bridge (3.9%), bone erosion (19.2%), osteosclerosis (3.0%), narrowing of intervertebral space (4.3%), compression fractures (3.5%), involvement of the paravertebral soft tissue (4.6%). Conclusions: The whole spinal lesions of SAPHO syndrome is characterized by BME and lipid deposition at the anterior corners of thoracic vertebra, which are distributed in jump and parallel manners. These characteristics may be diagnostic clue for SAPHO syndrome.]]></description>
<pubDate>Sun,20 Dec 2020 00:00:00  GMT</pubDate>
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<title><![CDATA[Magnetic resonance imaging findings of jaw in 9 patients with SAPHO syndrome]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2020.12.014</link>
<description><![CDATA[Objective: To investigate magnetic resonance imaging findings of jaw in patients with SAPHO syndrome and to improve our understanding of the disease. Materials and Methods: The MRI data of 9 patients with SAPHO in our department were reviewed. Two experienced radiologists read the films together, to assess the extent and degree of the bone marrow edema, hyperostosis, hypertrophy and fat infiltration of the mandible, the involvement of mandibular joints and surrounding tissues, and the diffusion limitation of lesions revealed by diffusion weighted imaging. The discrepancies were reached in consensus after discussion. Results: All the 9 patients of mandible with SAPHO exhibited varying degrees of abnormalities on magnetic resonance imaging. All of the patients show the marrow edema, mainly involving the body of the mandible, of which 8 cases are asymmetrical. Seven patients showed asymmetrical hyperostosis, of which 6 cases involved medulla. There was no fat infiltration. There were 5 cases showed peripheral soft tissue edema, of which 1 case involving adjacent muscles. All of the 9 cases were accompanied by multiple peripheral lymph nodes. One case underwent diffusion weighted imaging examination, and there was no obvious diffusion limitation in the lesion area. Conclusions: Magnetic resonance imaging can clearly show the range and degree of mandible involvement in SAPHO syndrome, which has certain characteristics, and providing help for clinical diagnosis and follow-up.]]></description>
<pubDate>Sun,20 Dec 2020 00:00:00  GMT</pubDate>
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<title><![CDATA[Correlation between quantitative magnetic resonance DTI values and neurological prognosis in patients with cervical spondylotic myelopathy]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2020.12.015</link>
<description><![CDATA[Objective: To investigate the correlation between the quantitative values of magnetic resonance diffusion tensor imaging (DTI) and the neurological prognosis in patients with cervical spondylotic myelopathy (CSM). Materials and Methods: A total of 102 patients with cervical spondylotic myelopathy treated in our medical imaging department from May 2017 to August 2018 were enrolled to receive decompression for cervical spondylotic myelopathy, and were divided into good group [Japanese Orthopaedic Association (JOA) recovery rate≥60%, n=49] and poor group (JOA recovery rate＜60%, n=53) according to the postoperative neurological recovery. The amount of DTI and the postoperative JOA score were observed, and the relationship between the quantitative DTI and JOA was also analyzed. Results: The proportion of T2WI high signal in the good group was lower than that in the poor group (χ2=17.21, P＜0.01). The postoperative fractional anisotropy (FA) in the good group was higher than that in the poor group, and the apparent diffusion coefficient (ADC) was lower in the postoperative group than in the poor group (t=3.59, 6.38, P＜0.001). There was no significant difference in λ∥ value and λ⊥ value between the two groups after surgery (t=0.592, 1.321, P=0.554, 0.189). The JOA score and JOA recovery rate in the good group were significantly higher than those in the poor group (t=7.22, 15.1, P＜0.001). Correlation analysis showed that postoperative FA value was positively correlated with postoperative JOA score (r=0.53, P＜0.001), that postoperative ADC value was negatively correlated with JOA recovery rate (r=-0.42, P＜0.001), and that postoperative λ⊥ value was negatively correlated with JOA recovery rate (r=-0.39, P=0.03). Conclusions: The quantitative DTI value is related to the postoperative neurological recovery and postoperative JOA score in patients with cervical spondylotic myelopathy, which can reflect the pathological state of the spinal cord and has a predictive value for the postoperative neurological function.]]></description>
<pubDate>Sun,20 Dec 2020 00:00:00  GMT</pubDate>
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<title><![CDATA[Application of MRI 3D-pCASL in patients with acute cerebral infarction]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2020.12.016</link>
<description><![CDATA[Objective: To investigate the clinical value of three-dimensional pseudo-continuous arterial spin labeling (3D-pCASL) in patients with acute cerebral infarction. Materials and Methods: A total of 84 patients with acute cerebral infarction (cerebral infarction group) were selected. The cerebral infarction group was divided into a hemorrhagic transformation group (35 cases) and a non-hemorrhagic transformation group (49 cases) according to the presence or absence of hemorrhagic transformation after thrombolysis. And 50 healthy volunteers were selected as the control group. All patients were examined by MRI 3D-pCASL, and statistical analysis was performed. Results: MRI of cerebral infarction patients showed large cerebral hemisphere hypoperfusion regions, while no distal vascular branches were shown. DWI showed significantly high signals, and ADC images showed significantly low signals. In 54 patients with cerebral infarction, the lesion was located in the right cerebral hemisphere, while in 30 patients with cerebral infarction. the absolute value of rCBF and ADC value in the core area of cerebral infarction were lower than those in the contralateral mirror area; the absolute value of rCBF and ADC value in both sides were lower than those in the healthy control group (P＜0.05). ROC curve analysis was carried out with 3D-pCASL image post-processing parameter rCBF, and the area under ROC was 0.915. The absolute value of peripheral blood flow (rCBF) and ADC values in the cerebral infarction core area of patients in the hemorrhagic transformation group were higher than those in the non-hemorrhagic transformation group (P＜0.05). ROC curve analysis was carried out with 3D-pCASL image post-processing parameter rCBF, and the area under ROC was 0.926. Conclusions: 3D-pCASL can display the hemodynamic state information of infarction lesions in patients with acute cerebral infarction. Combined with rCBF. It can objectively reflect the changes of cerebral ischemic infarction perfusion, and has certain value in predicting hemorrhage transformation after treatment, providing imaging basis for clinical diagnosis.]]></description>
<pubDate>Sun,20 Dec 2020 00:00:00  GMT</pubDate>
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<title><![CDATA[Clinical study on the distribution and stability of atherosclerosis in patients with diabetes and acute cerebral infarction based on magnetic resonance imaging]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2020.12.017</link>
<description><![CDATA[Objective: To analyze the effectiveness of MRI in the detection of plaque distribution in patients with diabetes and acute cerebral infarction and atherosclerosis, and to analyze the relevant factors that affect plaque stability. Materials and Methods: A retrospective analysis of 92 patients with acute cerebral infarction and carotid atherosclerotic plaques admitted to our hospital during the period from January 2018 to January 2020, including 34 patients with simple acute cerebral infarction atherosclerosis, diabetes complicated with acute cerebral infarction atherosclerosis. There were 58 patients with type sclerosis. Compare the blood vessel area, plaque thickness, plaque length, the narrowest blood vessel area and stenosis rate between the two groups to evaluate the plaque distribution and analyze the factors affecting the stability of the plaque, including hypertension, hyperlipidemia, coronary heart disease, drinking history, gender and diabetes, etc. Results: The number of plaque arteries on both sides of the 92 patients was 148, 62 in the simple acute cerebral infarction atherosclerosis group, and 86 with diabetic foot. Ninety-two males (46 cases), 56 females (28 cases), male plaque rate 83.64% (46/55), female plaque rate 75.68% (28/37), the difference between the two groups was statistically significant (P=0.013, t=6.872); among them, the proportion of vulnerable plaques in the simple sclerosis group was 70.97% (44/62), and the proportion of vulnerable plaques in the combined diabetes group was 83.72% (72/86). The difference between the two groups was statistically significant (P=0.001, t=7.671). In the control group (simple group), the area of the blood vessel at the infarct position, the thickness of the plaque, the length of the plaque, the area of the blood vessel at the most stenosis and the stenosis rate were (11.73±1.16) mm2, (1.17±0.18) mm, (5.73±0.62) mm, (1.63±0.32) mm2 and (76.43±17.52)%. In the observation group (combined group) the blood vessel area, plaque thickness, plaque length, the most stenosis blood vessel area and stenosis rate were (12.15±1.18) mm2, respectively (1.34±0.17) mm, (6.83±0.69) mm, (1.14±0.35) mm2 and (82.78±13.80)%. In male patients, the blood vessel area, plaque thickness, plaque length, the most stenosis blood vessel area and stenosis rate were (11.86±1.25) mm2, (1.12±0.17) mm, (5.72±0.83) mm,(1.43±0.25) mm2 and (82.35±9.72)%, the area of the blood vessel at the infarct site, the thickness of the plaque, the length of the plaque, the area of the blood vessel at the most stenosis and the stenosis rate were (11.53±1.28) mm2, (1.09±0.16) mm, (5.52±0.85) mm, (1.69±0.24) mm2 and (81.87±9.82)%. The degree of vascular stenosis in the combined group was higher than that in the simple group, and the degree of vascular stenosis in male patients was higher than that in female patients. The difference was statistically significant (P＜0.05). Coronary heart disease, hyperlipidemia, hypertension, history of drinking, diabetes, smoking history, and high BMI index are risk factors that affect plaque stability, and gender is a protective factor for plaque stability. Conclusions: MRI technology can be used as an effective method to assess the stability of plaque in patients with diabetes and acute cerebral infarction. The plaque length, thickness, vascular stenosis rate and infarct area of patients with diabetes are higher than those of simple acute cerebral infarction. In patients with pulmonary sclerosis, male patients have higher plaque length, plaque thickness, vascular stenosis rate and infarct area than female patients. Factors such as coronary heart disease, hypertension, diabetes, and smoking can aggravate the condition of patients with acute cerebral infarction and atherosclerosis. We should pay attention to living habits and reasonably control the pathogenic factors.]]></description>
<pubDate>Sun,20 Dec 2020 00:00:00  GMT</pubDate>
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<title><![CDATA[The value of conventional MRI combined with apparent diffusion coefficient in differential diagnosis of orbital tumors]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2020.12.018</link>
<description><![CDATA[Objective: To investigate the value of conventional MRI measurement combined with apparent diffusion coefficient (ADC) in the differential diagnosis of orbital tumor. Materials and Methods: A total of 25 patients with orbital mass confirmed by pathological examination received diffusion weighted imaging (DWI) and MRI scanning in our hospital from August 2016 to October 2019. The structural MRI imaging characteristics (tumor location, boundary, involved range, signal intensity, and upper space effect of T2WI) were retrospectively analyzed. ADC value and signal ratio (CER) between the tumor itself and the peripheral temporal muscle after enhancement were measured. T-test and chi-square test were used to compare qualitative and quantitative results of benign and malignant orbital masses. ROC curve was used to analyze the diagnostic efficacy of each diagnostic index for orbital benign and malignant tumors. Results: In this group of 25 patients with orbital tumors, 18 were malignant and 7 were benign. The efflux effect was observed in 7 patients with malignant tumors and 6 patients with benign tumors, there was a statistical difference between the two groups (P＜0.05). There were no statistically significant differences in the location, boundary, involved range and signal intensity of benign and malignant tumors (P＞0.05). The ADC and CER values of the benign and malignant tumor groups were (1.31±0.33)×10-3 mm2/s, 1.75±0.29, (0.81±0.11)×10-3 mm2/s, 1.42±0.15, respectively, with statistically significant differences between the two groups (P＜0.05).The optimal diagnostic threshold of orbital malignant tumor was ADC value 0.75×10-3 mm2/s, AREA under ROC was 0.820, sensitivity and specificity were 87.1% and 94.3%, respectively. The area under ROC was 0.965, and the sensitivity and specificity were 83.6% and 100.0%, respectively. Conclusions: Conventional MRI combined with ADC value has a good value for the differential diagnosis of orbital tumor.]]></description>
<pubDate>Sun,20 Dec 2020 00:00:00  GMT</pubDate>
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<title><![CDATA[Comparison of the clinical value of MRI and CT in the diagnosis of nasopharyngeal carcinoma]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2020.12.019</link>
<description><![CDATA[Objective: To study the application value of MRI and CT in the clinical diagnosis of skull base bone invasion in nasopharyngeal carcinoma. Materials and Methods: To retrospectively analyze the complete clinical datas of 70 patients with nasopharyngeal carcinoma who were pathologically confirmed in our hospital from February 2018 to July 2020. The comprehensive results of the patients’ clinical symptoms, imaging data and follow-up were taken as the skull base bone invasion criteria, then to analysis of the value of CT and MRI in the diagnosis of nasopharyngeal carcinoma skull base bone invasion. Results: Bone invasion of nasopharyngeal carcinoma skull base on CT is mainly manifested as thickening of cortical bone or hyperplasia and sclerosis, single or multi-site worm-like bone destruction; MRI is mainly manifested as bone marrow high signal displaced by medium signal. Among 70 patients, 24 patients were diagnosed as skull base bone invasion with CT, the detection rate was 34.3%, of which 17 cases were invaded by multiple sites. 51 cases of skull base bone invasion were diagnosed by MRI, of which including 31 cases of multi-site invasion, the detection rate was 72.9%, the detection rate of the two examination methods was statistically different (P＜0.05). Both CT and MRI examinations showed a higher incidence of the skull base bone invading the petrosal tip. Conclusions: MRI can significantly improve the detection rate in the diagnosis of nasopharyngeal carcinoma with bone invasion of the skull base, which provides imaging basis for clinicians to choose the treatment plan and is worthy of promotion.]]></description>
<pubDate>Sun,20 Dec 2020 00:00:00  GMT</pubDate>
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<title><![CDATA[Value of contrast enhanced energy spectrum mammography, dynamic contrast-enhanced MRI combined with DWI to evaluate different molecular typing of breast cancer]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2020.12.020</link>
<description><![CDATA[Objective: To investigate value of the contrast enhanced energy spectrum mammography (CESM), dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) and diffusion weighted magnetic resonance imaging (DWI-MRI) to evaluate different molecular typing of breast cancer. Materials and Methods: One hundred and sixty-two patients with breast cancer in our hospital from January 2017 to February 2020 were enrolled, and divided into four groups according to the results of molecular typing, Luminal A group (n=41), Luminal B group (n=69), Her-2 overexpression group (n=32), and triple negative group (n=20). All patients received CESM, DCE-MRI, and DWI-MRI examinations. The characteristics of CESM images, wash in rate (WIR), maximum enhancement (ME), time to peak (TTP) and apparent diffusion coefficient (ADC) were compared among four groups. Spearman correlation analysis was used to analyze the correlation between CESM image characteristics and breast cancer molecular typing, and receiver operating characteristic curve (ROC) was used to analyze predictive value of MRI parameters on the breast cancer molecular typing. Results: The calcification characteristics had significant difference among four groups (P＞0.05), while significant difference was found in mass diameter, mass morphology, mass boundary, enhancement, features of axillary lymph node enlargement and ME, TTP, WIR and ADC among four groups (P＜0.05). There was no correlation between calcification and breast cancer molecular typing (P＞0.05), while the tumor diameter, tumor morphology, tumor boundary, enhancement, axillary lymphadenopathy had significant correlation with breast cancer molecular typing (P＜0.05); the AUC, accuracy and cut-off value of WIR combined ADC in the prediction of triple negative breast cancer were 0.898 (95% CI: 0.846—0.950), 82.65%, and 0.653. The AUC, accuracy and cut-off value of ME in the prediction of Luminal B breast cancer were 0.678 (95% CI: 0.591—0.765), 72.10%, and 0.442. The AUC, accuracy and cut-off value of TTP in the prediction of Her-2 overexpressed breast cancer were 0.773 (95% CI: 0.691—0.855), 73.45%, and 0.469. Conclusions: Value of CESM, dynamic contrast-enhanced MRI combined with DWI has certain guiding significance in the judgment of breast cancer molecular typing, and is expected to be applied in the prediction of breast cancer molecular typing.]]></description>
<pubDate>Sun,20 Dec 2020 00:00:00  GMT</pubDate>
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<title><![CDATA[The differential diagnosis of benign and malignant breast tumors with MRI quantitative and semi-quantitative parameters and the correlation analysis with biological indicators of breast cancer]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2020.12.021</link>
<description><![CDATA[Objective: To investigate the differential diagnosis of MRI diffusion weighted imaging (DWI) and semi-quantitative dynamic contrast-enhanced (DCE) parameters for benign and malignant breast tumors and their correlation with the biological parameters of breast cancer. Materials and Methods: The clinical datas of 50 patients with breast tumor in our hospital were retrospectively analyzed. According to the pathological results after surgical resection, they were divided into the breast cancer group (31 cases) and the benign tumor group (19 cases). Immunohistochemical examination was performed on all the breast cancer patients, and they were further divided into the PR, ER and HER-2 positive groups and the progesterone receptor (PR), estrogen receptor (ER) and human epithelial factor receptor-2 (HER-2) negative groups. All patients were examined by DWI and DCE. The apparent diffusion coefficient (ADC) and the peak time (Tmax), the early enhancement rate (EER) and the peak enhancement rate (Emax) of DCE were measured. Immunohistochemistry was used to detect the biological indicators of breast cancer, such as cell proliferation antigen markers Ki-67, PR, ER and HER-2. The differences of MR quantitative parameters and semi-quantitative parameters in benign and malignant breast tumors were compared, and the correlation between these parameters and biological indicators of breast cancer was analyzed. Results: The EER in the breast cancer group was higher than that in the benign tumor group (P＜0.05), while ADC, Tmax and Emax values were all lower than that in the benign tumor group (P＜0.05). There was no difference in ADC values between the positive group and the negative group (P＞0.05). The Tmax and Emax values of the positive breast cancer PR, ER and HER-2 groups were all lower than those of the negative group (P values were all less than 0.05). EER was significantly higher in the positive group of PR, ER and HER-2 than in the negative group (P＜0.05). EER was positively correlated with Ki-67 expression (r=0.49, P＜0.01). ADC, Tmax and Emax values were negatively correlated with Ki-67 expression (r=-0.52, -0.45 and -0.43, all P values were less than 0.05). Conclusions: DWI quantitative parameters and DCE semi-quantitative parameters can not only be used in the differential diagnosis of benign and malignant breast tumors, but also can be used as the prediction index of biological behavior of breast cancer, which provide information for clinicians to treate.]]></description>
<pubDate>Sun,20 Dec 2020 00:00:00  GMT</pubDate>
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<title><![CDATA[MR pulmonary angiography in patients with pulmonary embolism and its correlation with right heart function and prognosis]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2020.12.022</link>
<description><![CDATA[Objective: To investigate the characteristics of MR pulmonary angiography in patients with pulmonary embolism (PE) and its correlation with right heart function and prognosis assessment. Materials and Methods: A retrospective analysis was performed on 90 PE patients, who were divided into mild PE group, severe PE group, group with good prognosis and the group with poor prognosis according to their condition and prognosis. All patients underwent MR pulmonary angiography to calculate embolization score, perfusion defect score, right and left ventricular short axis maximum diameter ratio (RV/LV), and pulmonary artery diameter. To compare the features of MR pulmonary angiography in patients with different degrees of severity, as well as the differences in embolization score, perfusion defect score, RV/LV, and pulmonary artery diameter among different groups, and analyze their correlation, and analyze their prognostic value through ROC curve. Results: In mild PE patients, 254 segments (69.0%) of pulmonary artery branches showed blotchy and patchy filling defects by MR pulmonary angiography, which was significantly higher than that in severe PE group (P＜0.05). MR angiography showed 306 pulmonary artery branches (95.6%) as subsegmental or segmental filling defects in the severe group, with a significantly higher incidence than that in the mild group (P＜0.05). The embolization score, defect score, RV/LV and pulmonary artery diameter of severe PE group were significantly higher than those of mild PE group (P＜0.05). The embolization score and defect score of the group with poor prognosis were significantly higher than that of the group with good prognosis (P＜0.05). There was a significant positive correlation between embolization score and defect score, RV/LV, and pulmonary artery diameter (P＜0.05). ROC curve analysis showed that the area under the curve of defect score and embolization score for PE prognosis were 0.911 (95% CI: 0.625—0.966) and 0.796 (95% CI: 0.800—1.000), respectively. Conclusions: MR pulmonary angiography can be used to evaluate the severity of PE, and it has a certain diagnostic value for the function and prognosis of right heart.]]></description>
<pubDate>Sun,20 Dec 2020 00:00:00  GMT</pubDate>
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<title><![CDATA[Analysis of the diagnostic efficacy of T2WI combined with DWI and DCE-MRI in peripheral chronic prostatitis and prostatic cancer]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2020.12.023</link>
<description><![CDATA[Objective: By comparing the three sequences of T2WI and T2WI combined with DWI and DCE and their combined efficacy in the diagnosis of chronic prostatitis and prostate cancer, the optimal sequence of MRI in the diagnosis of prostate lesions was discussed. Materials and Methods: A total of 43 lesions were selected from 38 patients with low T2WI signal found in peripheral prostate gland by MRI examination from June 2014 to June 2020, and the clinical pathological and imaging data were retrospectively analyzed to summarize and analyze the diagnostic efficacy of each sequence and combined application. Results: There were 26 lesions in chronic prostatitis and 17 lesions in prostate cancer. The differences between the ADC values of inflammatory lesions, cancer foci and normal tissues were statistically significant by variance analysis (P＜0.05). ADC value 0.92×10-3 mm2/s was used as the standard for detection of prostate cancer, with sensitivity of 96.2% and specificity of 88.2%. T2WI: The sensitivity and specificity of the diagnosis of prostate cancer were 52.94% and 69.23%, respectively, and the accuracy of the diagnosis of prostatitis and prostate cancer was 62.79%. The diagnostic efficacy of T2WI was compared with that of surgery and pathology, with poor consistency (Kappa=0.222). T2WI+DWI: The diagnostic sensitivity and specificity of T2WI+DWI for prostate cancer were 94.12% and 82.46% respectively, and the diagnostic accuracy for prostatitis and prostate cancer was 90.70%. The diagnostic efficacy of T2WI+DWI was compared with that of surgery and pathology, and the diagnostic efficacy was very satisfactory (Kappa=0.809), which was comparable to the combined application of T2WI+DWI+DCE. Conclusions: The diagnostic efficacy of T2WI+DWI is not significantly different from that of T2WI+DWI+DCE, so it is worth popularizing and applying.]]></description>
<pubDate>Sun,20 Dec 2020 00:00:00  GMT</pubDate>
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<title><![CDATA[Imaging evaluation of lumbar spine in middle-aged and elderly patients using MR fat quantification technique combined with quantitative computed tomography]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2020.12.024</link>
<description><![CDATA[Objective: To investigate the correlation between fat fraction (FF), R2* and bone mineral density (BMD) of lumbar vertebrae in middle-aged and elderly people of different genders. Materials and Methods: The FF and R2* values of each lumbar vertebra were measured by MRI fat quantitative technique (mDIXON-Quant), and quantitative computed tomography (QCT) was used to measure the BMD of each lumbar vertebra in 40 middle-aged and elderly patients (20 males and 20 females). The BMD, FF and R2* values of various lumbar vertebrae of different genders were compared by SNK test. The BMD, FF and R2* values of lumbar vertebrae of different genders were compared by t test. Pearson correlation analysis was conducted to analyze the correlation between FF and R2* values with BMD of each lumbar vertebrae of different genders. Results: The BMD and R2* value of each vertebral body between the middle-aged and elderly people in different genders showed no statistically significant difference (P＞0.05). There were statistically significant differences in FF value of each vertebral body between the middle-aged and elderly people in different genders (P＜0.05). The values of L4FF and L5FF were greater than L1FF in both male and female groups, and the value of L4FF in male group was greater than L2FF. There was no statistically significant difference in BMD and FF between male and female groups (P＞0.05). There was statistically significant difference in R2* between male and female groups (P＜0.05), and R2* in male group was greater than that in female group. The BMD and FF values of the lumbar spine in the middle-aged and elderly people of different genders were negatively correlated (rmale=-0.76, rfemale=-0.77, P＜0.05), and were positively correlated with R2* value (rmale=0.56, rfemale=0.45, P＜0.05). Conclusions: There was a certain correlation between lumbar body BMD with FF and R2* values in middle-aged and elderly people, and R2* values in middle-aged and elderly women were lower than those in men. Besides, the FF values in lower lumbar spine were higher than those in upper lumbar spine.]]></description>
<pubDate>Sun,20 Dec 2020 00:00:00  GMT</pubDate>
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<title><![CDATA[Application situation and progress of amide proton transfer imaging in central nervous system]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2020.12.027</link>
<description><![CDATA[Amide proton transfer (APT) imaging is a rapidly developed and mature method in chemical exchange saturation transfer imaging, based on the theory of magnetization transfer and chemical exchange, APT imaging assays changes in intracellular protein concentration and pH by detecting the rate at which amide-protons on free proteins and polypeptide chains exchange with hydrogen ions in water. As a non-invasive cellular molecular level magnetic resonance technique, APT imaging can provide important imaging information in brain injury, brain tumor, neurodegenerative disease and brain development in children, and provide help for clinical diagnosis, treatment and prognosis. This paper mainly describes the application status and progress of APT imaging in the central nervous system.]]></description>
<pubDate>Sun,20 Dec 2020 00:00:00  GMT</pubDate>
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<title><![CDATA[Application of magnetic resonance mapping technology in the differentiation of left ventricular hypertrophic diseases]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2020.12.028</link>
<description><![CDATA[Early diagnosis of left ventricular hypertrophy disease still faces many challenges, and it is difficult to implement effective treatment in the early stage of the lesion. Magnetic resonance is the gold standard for noninvasive diagnosis of myocardial disease. MR mapping technology can quantitatively analyze the myocardial characteristics of different diseases, and supplement some information about differential diagnosis. Combined with LGE (late gadolinium enhancement) technology, it greatly improves the early diagnosis efficiency of the disease, and has important risk assessment and treatment guidance value. In this paper, the characteristics of myocardial mapping parameters in patients with left ventricular hypertrophy were reviewed in order to provide necessary information for differential diagnosis.]]></description>
<pubDate>Sun,20 Dec 2020 00:00:00  GMT</pubDate>
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