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<title>Chinese Journal of Magnetic Resonance Imaging RSS feed</title>
<link>http://med-sci.cn/cgzcx/en/contents_list.asp?issue=201002</link>
<language>zh-cn</language>
<copyright>An RSS feed for Chinese Journal of Magnetic Resonance Imaging</copyright>
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<title><![CDATA[Three-dimensional high resolution venography using susceptibility weighted imaging at 7T]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.3969/j.issn.1674-8034.2010.02.002</link>
<description><![CDATA[Objective: Ultra-high-field strength MRI takes advantage of markedly improved signal-to-noise ratio (SNR) and contrast for brain venography. Imaging very small transcerebral veins and venules is now possible. In this report, we describe susceptibility weighted imaging (SWI) optimized at 7T for a high quality and substantially improved 3D venography. Materials and Methods: Ten volunteers were scanned to determine imaging parameters for best visualization of veins using SWI on both 7T and 3T whole-body human MR systems. SWI uses a fully flow velocity-compensated 3D gradient echo sequence. For both 3T and 7T scans, we used combinations of TR, TE, bandwidth and ﬂ ip angle varying from 30-45 ms, 13-26 ms, 80-140 Hz/pixel and 10-25°, respectively. The same high-pass filter was applied to the phase images for both the 3T and the 7T scans with the same phase multiplication factor of 4 to generate the minimum intensity projection (mIP) images. The quantitative image evaluation was based on magnitude, phase, susceptibility weighted, and mIP images. Resluts: The best SWI contrast was obtained at TE=T2* of venous blood, with TE=28 ms for 3T and TE=16 ms for 7T. The optimal ﬂ ip angle at 3T and 7T was roughly 15°. Both signal-to-noise ratio and contrast-to-noise ratio showed marked increases in SWI venographic images at 7T versus 3T. Compared to 3T, SWI at 7T allows for thinner partitions (1 mm and lower) and much higher in-plane resolution (215 μm) and reveals numerous additional small veins and venules. Conclusion: Preliminary results indicate the promise of using ultra-high ﬁ eld SWI to generate high resolution and high quality venography by virtue of the greatly increased SNR and susceptibility contrast at 7T.]]></description>
<pubDate>Sat,20 Feb 2010 00:00:00  GMT</pubDate>
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<title><![CDATA[Accuracy of MR imaging to identify the coronary artery plaque: comparison with intravascular ultrasound]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.3969/j.issn.1674-8034.2010.02.003</link>
<description><![CDATA[Objective: To evaluate the ability of black blood coronary arterial wall MR imaging to identify the coronary artery plaque, using intravascular ultrasound (IVUS) as the golden standard. Materials and Methods: Eleven patients (mean age 61.8±9.7 years, 6 men and 5 women) who plan to do IVUS or had done IVUS examinations, but had not done percutaneous coronary intervention (PCI), underwent black-blood coronary wall MR imaging within 10 days before or after PCI respectively. All scans were performed on a 1.5T MR scanner. Cross-sectional coronary wall imaging was acquired using a 2D double-inversion-recovery, ECG-triggered, navigator-gated, fat-suppressed, Turbo-Spin-Echo (TSE) sequence on the lesion of coronary artery from the ostium to the middle segment continuously without gap. The vessel cross-sectional area (CSA), luminal CSA, maximal wall thickness, plaque burden, CNR [(SIvessel wall – SIperivascular area) / SDnoise) and SNR (SIvessel wall / SDnoise) were measured in each slice which were then compared with the IVUS images. IVUS were divided into 5 mm segments to compare side by side with MRI. Results: Nine coronary arteries and 37 slices from 9 patients were imaged and analyzed by both MRI and IVUS. Two patients were ruled out due to long examination time. Twenty of 37 slices were found plaques on both IVUS and MRI; the plaque burden, SNR, CNR in the coronary wall containing plaque were greater compared to the normal coronary wall (0.70±0.11 vs 0.58±0.14, 1.95±0.39 vs 1.48±0.21, 5.47±2.06 vs 2.99±0.78, respectively, P<0.05). There were good correlation between MRI and IVUS in vessel CSA, lumen CSA, and plaque burden.(13.66±4.52 vs 14.92±6.37, 4.62±2.23 vs 6.03±3.85, 0.63±0.13 vs 0.60±0.14, respectively, P<0.05). Conclusion: Coronary wall MRI can identify coronary plaque in proximal segments.]]></description>
<pubDate>Sat,20 Feb 2010 00:00:00  GMT</pubDate>
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<title><![CDATA[MR imaging findings in noncompaction of ventricular myocardium]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.3969/j.issn.1674-8034.2010.02.004</link>
<description><![CDATA[Objective: To investigate the clinical value of magnetic resonance imaging (MRI) in the diagnosis of noncompaction of ventricular myocardium (NVM). Materials and Methods: We retrospectively analyzed the clinical manifestations and MRI ﬁ ndings of 10 NVM patients. Results: Ten patients (9 males and 1 female) presented with different clinical features. One patient was referred with no symptom, 9 patients with different degree of chest distress and palpitations, and the most serious manifestations happened in 1 adolescent with whole heart failure and thrombus in right subclavian vein, vena cava superior and left ventricular apex. Abnormal findings of electrocardiogram were found in 8 patients including hypertrophy (2 patients) and cardiac arrhythmia (6 patients). Noncompaction myocardium involved in left ventricular in 3 patients, right ventricular in 2 patients and biventricular in 5 patients. The most frequently involved segments were apex and the least determined segment were basal-septal. The ratio of thickness of the trabecular and compact layers were more easily identiﬁ ed by cine sequence in diastole and the slower ﬂ ow in trabecular were more easily determined by Turbo spin echo sequence. Conclusion: Noncompaction of ventricular myocardium can be diagnosed accurately with cardiac MR multiple plane and sequences imaging.]]></description>
<pubDate>Sat,20 Feb 2010 00:00:00  GMT</pubDate>
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<title><![CDATA[Effects of neoadjuvant chemoradiotherapy prior to surgery on rectal cancer assessing by DCE-MRI]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.3969/j.issn.1674-8034.2010.02.005</link>
<description><![CDATA[Objective: To evaluate dynamic contrast-enhanced MR imaging (DCE-MRI) in assessing pathologic responses in rectal cancer treated with neoadjuvant chemoradiotherapy (NCRT), and to compare the diagnostic accuracy of T2WI and DCE-MRI in the preoperative T and N staging of rectal cancer. Materials and Methods: Forty patients with pathologically proven primary rectal cancer were enrolled in this study, 18 patients had no preoperative treatments, 22 patients treated with NCRT. DCE-MRI was performed in all patients on GE 1.5 T Twinspeed HD MR scanner. The rectal cancer stage was made according to the TNM classiﬁ cation criteria. Preoperative MRI assessment was compared with postoperative histopathological findings. Parameters of DCE-MRI curves including type of enhancement, the time of maximum uptake, the uptake velocity T, were analyzed. The normal rectum part was selected as control. Results: (1) For rectal cancer without NCRT, DCE-MRI had an accuracy of 83.3% for T staging, and T2WI had an accuracy of 66.7%. For predicting a clear circumferential resection margin (CRM), DCE-MRI had an accuracy of 88.2%, and T2WI had an accuracy of 70.7%. Lymph nodes of diameter more than 2 mm could be found in DCE-MRI and T2WI. (2) For rectal cancer treated with NCRT, DCE-MRI had an accuracy of 86.4% for T staging and 81.8% for N staging in preoperative tumor restaging, and had an accuracy of 100% for predicting a clear CRM. However, T2WI could not distinguish stages for the tumor. (3) The T value of the lesions was equal to or lower than the normal rectum part in pathologic complete response (PCR) group, while the T value of the lesions was higher than normal rectum part in non-PCR group. Conclusion: DCE-MRI has high accuracy for preoperative tumor restaging, and play an important role for predicting circumferential resection margin status of rectal cancer treated with NCRT.]]></description>
<pubDate>Sat,20 Feb 2010 00:00:00  GMT</pubDate>
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<title><![CDATA[Clinical value of assessing the activity of rheumatoid arthritis using revised MRI scoring system]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.3969/j.issn.1674-8034.2010.02.006</link>
<description><![CDATA[Objective: To investigate the clinical value of assessing the activity of rheumatoid arthritis using revised MRI scoring system. Materials and Methods: MR images of both wrists and the 2nd to 5th metacarpophalangeal joints of 77 patients with RA were analyzed. MRI scores of each patient were acquired using a revised OMERACT RAMRIS Scoring System, which was based on initial OMERACT RAMRIS Scoring System and added the scores of the proximal interphalangeal joints, distal interphalangeal joints and tenosynovistis.The intra- and inter-reader reliability of MRI scoring system was assessed. The relationships between MRI score of each sign, between MRI score and clinical data were analyzed respectively. Results: There was a signiﬁ cant correlation between MRI total score and CRP (r= 0.322, P=0.009), ESR (r=0.406, P=0.001), between bone edema score, tenosynovitis score and CRP (r=0.348 and 0.414, P=0.017 and 0.004), between tenosynovitis score and the number of pain joints (r=0.329, P=0.013), between synovitis score and bone erosion score (r=0.542, P=0.000), bone edema score (r=0.365, P=0.001), tenosynovits score (r=0.610, P=0.000), between bone erosion score and bone edema score (r=0.543, P=0.000), tenosynovitis score (r=0.430, P=0.000), between bone edema score and the tenosynovitis score (r=0.671, P=0.000). Conclusion: The revised MRI scoring system can be used to assess the activity of RA semi-quantitatively and play an important role in clinical study.]]></description>
<pubDate>Sat,20 Feb 2010 00:00:00  GMT</pubDate>
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<title><![CDATA[MRI manifestations of "dural tail sign" in meningioma and its related pathology]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.3969/j.issn.1674-8034.2010.02.007</link>
<description><![CDATA[Objective: To evaluate the MRI features, pathological foundation and clinical significance of the "dural tail sign" in the meningioma. Materials and Methods: Forty-ﬁ ve patients with pathologically proved meningioma were enrolled in this study. Before resection of the meningioma, all patients underwent conventional and contrast-enhanced MR examinations and all possessed the "dural tail sign" on contrast-enhanced MR images. The dural tails were resected during the operation and made pathological examination together with the meningioma mass. The pathological components of the dural tail were all observed. Results: Pathological examination of dural tails showed that 37 cases had tumor cells inﬁ ltration (82.2%), 3 cases were only ﬁ brous hyperplasia (6.7%), 5 cases had no tumor cells inﬁ ltration and only seen vessel dilation and inﬂ ammatory cell inﬁ ltration (11.1%). The inﬁ ltration of tumor cell in the "dural tail sign" of meningioma was related with tumors’ surrounding edema and meningioma grade (P<0.05), and was not related with the size of the meningioma and shape of the "dural tail sign" (P>0.05). Conclusion: Most of "dural tail sign" tissues in the meningioma have been observed tumor cells inﬁ ltration. The "dural tail sign" tissue should be resected completely when performing the meningioma resection.]]></description>
<pubDate>Sat,20 Feb 2010 00:00:00  GMT</pubDate>
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<title><![CDATA[Diffusion tensor imaging parameter maps of projection fibers from the brain in right-handed healthy young volunteers]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.3969/j.issn.1674-8034.2010.02.008</link>
<description><![CDATA[Objective: To quantitatively analyze the diffusion tensor imaging parameter maps of the right-handed young human projection ﬁ bers, reveal the signiﬁ cance and correlation of three diffusion  parameters: fractional anisotropy (FA), mean diffusivity (MD) and T2-weighted trace. Materials and Methods: Thirty right-handed healthy young volunteers (16 men, 14 women; mean age of 28.2 years) underwent diffusion tensor imaging and conventional MR imaging with a GE 3T MR system. The FA, MD and T2-weighed trace were determined at six-pair of parts of the projection fibers. The gender, lateral and regional differences of the parameters values were tested, the correlation between different parameters were analyzed. Results: (1) No signiﬁ cant differences were found in FA, MD and T2-weighted trace due to gender. (2) The FA value of projection ﬁ bers in the left pons was superior to that in the right (P=0.011), whereas the other five-pair regions of the fibers had no lateral differences. T2-weighted trace had lateral differences in the pons, peduncle, anterior limb of internal and centrum semiovale (P value was 0.000 to 0.017). (3) The order of FA values was peduncle > posterior limb of internal capsule > genu of internal capsule > anterior limb of internal capsule, pons > centrum semiovale. (4) In the projection ﬁ bers, T2-weighted trace had negative correlation with FA and MD (r =-0.169, P =0.024; r =-0.149, P =0.047). Conclusion: In showing the projection ﬁ bers, FA can give more details than the other two parameters. FA and MD are different parameters which reﬂ ect different aspect of the water molecule diffusion. T2-weighted trace map should be analyzed combining with FA, MD map and conventional MR imaging.]]></description>
<pubDate>Sat,20 Feb 2010 00:00:00  GMT</pubDate>
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<title><![CDATA[Comparison of three different post-processing techniques on the absolute quantitation of 1H MR spectroscopy]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.3969/j.issn.1674-8034.2010.02.009</link>
<description><![CDATA[Objective: To compare the accuracy of three different kinds of post-processing techniques: LCModel, Functool and SAGE software in the estimation of metabolite concentration. Materials and Methods: Fourteen health volunteers with an average age of 26.1 years old were selected for this study. All the 1H MR spectroscopy data were collected by STEAM sequence. The scan parameters were as followed: TE=30 ms, TR=3000 ms. Results: Except for NAA/Cr, the ratios of Cho/Cr and mI/Cr were signiﬁ cant different for the three post-processing technologies. Cho/Cr obtained from LCModel software was obviously deviated from the reference. NAA/Cr and mI/Cr analyzed by Functool software were also deviated from the reference. What’s more, the concentration translated from the peak areas through a known formula, Cho/Cr and mI/Cr were still deviated from the reference when we analyzed the spectrum by SAGE software. Conclusion: Compared with Functool and SAGE softwares, LCModel software shows an advantage at the quantitation because of simulating the base-line spectrum and handling the systematic error. However, LCModel software was still weak at the calculation of metabolite concentration.]]></description>
<pubDate>Sat,20 Feb 2010 00:00:00  GMT</pubDate>
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<title><![CDATA[syngo Orthopedic MRI techniques]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.3969/j.issn.1674-8034.2010.02.010</link>
<description><![CDATA[This article summarizes the orthopedic MR imaging techniques provided by Siemens Ltd. Small-sized dedicated local coils can support high resolution imaging of joints, and multiple elements of these coils realize parallel imaging. Transmitter-receiver coil can avoid aliasing from other anatomies and reduce whole body SAR; Some advanced sequences are introduced, including: syngo BLADE which can reduce motion artifact, three point tse DIXON which can reduce the artifact from metal implants and syngo SPACE with which isotropic data can be acquired; Besides morphological imaging, biochemical imaging can be achieved by syngo MapIt with simplified in-line workflow. With all above the-state-of-art techniques, clinical oriented protocols optimized for every joint are provided.]]></description>
<pubDate>Sat,20 Feb 2010 00:00:00  GMT</pubDate>
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<title><![CDATA[Perfusion-weighted imaging of rabbit models with hepatic VX2 tumor after three-dimensional conformal radiotherapy: compared with pathological changes]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.3969/j.issn.1674-8034.2010.02.011</link>
<description><![CDATA[Objective: To analyze the perfusion parameters and related pathological changes of rabbit VX2 liver cancer after three-dimensional conformal radiotherapy (3DCRT) and discuss the availability of perfusion-weighted imaging (PWI) as a clinical diagnosis of liver tumors, postoperative monitoring and efﬁ cacy evaluation. Materials and Methods: Of 13 New Zealand rabbits were implanted in liver with VX2 tumor by tissue block, each rabbit was treated by single 3DCRT. All of them were performed PWI and enhanced scanning 10 days before and after the radiotherapy by using a 1.5T MR scanner with EPI-SE sequence and SENSE technology. Finally, image quality of 3 rabbits were not good enough, 13 were enrolled  into statistic. Selecting the regions of interests (ROI) of lesions and surrounding normal liver tissue, perfusion values were measured and statistically analyzed. Maximal signal reduction slope (SRSmax) of the signal intensity versus time curves were created as quantitative index, specimens of vascular endothelial growth factor (VEGF) were examined and compared with the perfusion-weighted images. Results: After radiotherapy, the SRSmax value of central and surrounding of tumor were statistically decreased than that before radiotherapy (P<0.05), but there were no differences in normal liver parenchyma of tumor border; the SRSmax decreasing of different ROI was accordant to the range of the spoiled vascular endothelial growth factor (r=0.487, P=0.01). Conclusion: PWI can reflect the microcirculation and hemodynamic changes of rabbit models with hepatic VX2 tumors after 3DCRT. SRSmax can be used as an evaluating indicator for living tumor microvessels.]]></description>
<pubDate>Sat,20 Feb 2010 00:00:00  GMT</pubDate>
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<title><![CDATA[MRI of prostate stem cell antigen specific MR molecular probe in human prostate cancer at 3.0 T: in vitro experimental study]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.3969/j.issn.1674-8034.2010.02.012</link>
<description><![CDATA[Objective: To investigate the feasibility of in vitro MRI of 7F5@GoldMag probe in prostate cancer on a clinical 3.0 T MR system. Materials and Methods: GoldMagTM-CS nanoparticles solution in different concentration was scanned to ascertain the lowest concentration that can be detected by MR system. Prostate cancer cell line PC-3 and hepatoma cell line SMMC-7721 were cultured (hepatoma cell line SMMC-7721 was control group). The two cell lines were cross-matched with 7F5@ GoldMag and non-related IgG@GoldMag. Then, the mixture was incubated at 37℃ for 1 hour. T2WI was obtained and the signal intensity was measured in each group. Statistical analysis were performed to assess the statistical differences of signal intensity by using one-way ANOVA with SPSS 11.5 software package as parameters were normally distributed, P<0.05 was considered as statistically significant difference. Results: The T2WI signal intensity of GoldMagTM-CS was signiﬁ cantly lower than that of agarose gel even if the former was diluted by 640 times. 7F5@ GoldMag could specifically decrease T2WI signal intensity of PC-3 cells in vitro. Conclusion: 7F5@GoldMag has target-directed enhancement effect in prostate cancer cell lines in vitro by using a clinical 3.0 T MR scanner.]]></description>
<pubDate>Sat,20 Feb 2010 00:00:00  GMT</pubDate>
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<title><![CDATA[Research and progress of magnetic resonance spectroscopy in diagnosis and radiotherapy of prostate cancer]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.3969/j.issn.1674-8034.2010.02.014</link>
<description><![CDATA[Magnetic resonance spectroscopy (MRS) is an approach that can non-invasively detect the composition and content evolvement of some metabolic materials in vivo, reflecting the pathophysiological processes at the molecular level. We reviewed the literatures about MRS application in the diagnosis and radiotherapy of prostate cancer, as well as the recent progress in the prostate MRS technology.]]></description>
<pubDate>Sat,20 Feb 2010 00:00:00  GMT</pubDate>
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