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<title>Chinese Journal of Magnetic Resonance Imaging RSS feed</title>
<link>http://med-sci.cn/cgzcx/en/contents_list.asp?issue=201803</link>
<language>zh-cn</language>
<copyright>An RSS feed for Chinese Journal of Magnetic Resonance Imaging</copyright>
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<title><![CDATA[The correlation between brain MR amide proton imaging and scores of clinical psychometric scales in patients with Alzheimer<sup><sup>,</sup></sup>s disease]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2018.03.001</link>
<description><![CDATA[Objective: To evaluate the correlation between MR amide proton transfer (APT) imaging values of cerebral structures and neuropsychological scores in patients with Alzheimer's disease (AD). Materials and Methods: Twenty-one AD patients and 19 age- and sex- matched normal controls underwent APT and structural MR imaging. The magnetic resonance ratio asymmetry (MTRasym) values at 3.5 ppm of bilateral hippocampi (Hc), temporal white matter regions, occipital white matter regions and cerebral peduncles were measured on the oblique axial APT images. All the subjects were evaluated by Mini-Mental State Examination (MMSE) and clinical dementia rating (CDR). MTRasym (3.5 ppm) values of the cerebral structures between two groups were compared with independent-samples t test. Controlling for age and years of education, partial correlation analysis was used to investigate the correlation between the various MR imaging measures and MMSE, CDR scores among all the subjects. Results: Compared to normal controls, MTRasym (3.5 ppm) in bilateral hippocampi were significantly increased in AD patients [right: (0.86±0.32)% and (1.42±0.35)%, t=5.158, P=0.000; left: (0.84±0.31)% and (1.39±0.33)%. T=5.225, P=0.000]. MTRasym (3.5 ppm) values of bilateral Hc were significantly negatively correlated with MMSE scores (right r=-0.637, P=0.000. left r=-0.611, P=0.000) and positively correlated with CDR scores (right r=0.686, P=0.000. left r=0.658, P=0.000). Conclusions: APT imaging can show sensitively hippocampal abnormal metabolite based on increased proteins and peptides in patients with AD, which suggests the technique is a useful tool to diagnose AD and monitor the disease.]]></description>
<pubDate>Tue,20 Mar 2018 00:00:00  GMT</pubDate>
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<title><![CDATA[Preliminary research of the classification of the brain acute stroke by diffusion kurtosis imaging parameters]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2018.03.002</link>
<description><![CDATA[Objective: To classify the acute stroke lesions according to the diffusion kurtosis imaging (DKI) parameters and discuss the significance of the classification in diagnosis and prognosis. Materials and Methods: We chose 46 acute stroke lesions in brain and divided into 4 types. MK, Ka and Kr show hyper-intensity in Type Ⅰ. MK, Ka and Kr show isointensity or hypo-intensity in Type Ⅱ. MK, Ka and Kr show mixed signal intensity in Type Ⅲ. The ranges or intensity of MK, Ka and Kr are diverse in Type IV. The difference of DKI parameters between four types was accessed by one-way analysis of variance. We chose one case of each type to analyze the prognosis. Results: It shows that MK%, Ka% and Kr% of four types have a significant difference. Other parameters have no significant difference. Type Ⅰ may indicate the bad prognosis. Type Ⅱ and Type Ⅲ may indicate better prognosis, the volume of lesions may decrease. Conclusions: To some degree, the classification of acute stroke lesion by DKI parameters has significance in diagnosis, treatment and prognosis.]]></description>
<pubDate>Tue,20 Mar 2018 00:00:00  GMT</pubDate>
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<title><![CDATA[The alterations of resting-state brain functional connectivity after physiological food intake]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2018.03.004</link>
<description><![CDATA[Objective: To explore the alterations of resting state brain functional connectivity after physiological food intake. Materials and Methods: Forty-two healthy subjects were divided into three groups in a balanced order according to the demographic characteristics. To maximize the differences of gastrointestinal activity of the three groups, three medicines were given to the three groups, including Domperidone (promote group), Otilonium Bromide (inhibition group), and dummy (control group). All the participants were given standard experiment diet for breakfast. And the resting state fMRI scanning was performed at 4 different gastrointestinal physiological states, specifically fasting, postprandial immediately, 2 h postprandial and before lunch. During data analysis, the posterior cingulate/precuneus (PCC/PCu) were selected as the seed to calculate the functional connectivity (FC) throughout the whole brain. Then the repeated measure analysis of variance (ANOVA) was used to investigate the brain areas with significant differences across the time and medicine. The brain regions with significant differences were further extracted the Z functional connectivity value which were subsequently involved into the post hoc analysis. Results: The main effect of time: significant FC changes across time were found in the right orbitofrontal cortex/putamen/thalamus, right supramarginal gyrus, and right Rolandic lobe (P＜0.05). The main effect of medicine: significant FC changes across medicine were found in the right precuneus, left middle temporal gyrus, left lingual gyrus, right middle temporal gyrus, right superior frontal gyrus, bilateral orbitofrontal cortex and left middle frontal gyrus (P＜0.05). Conclusions: The FC of the food reward system, the right thalamus and somatosensory regions demonstrated changes after physiological food intake, showing right lateralization. While no significant differences were found in these areas across medicine. This study may provide possible implications for analyzing the potential effects of food intake on the results of conventional fMRI experiments.]]></description>
<pubDate>Tue,20 Mar 2018 00:00:00  GMT</pubDate>
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<title><![CDATA[Histogram texture analysis on vulnerability of symptomatic plaques in intracranial atherosclerosis]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2018.03.005</link>
<description><![CDATA[Objective: The aim of the present study is to evaluate differences in histogram features between symptomatic and asymptomatic plaques in intracranial atherosclerotic disease on HR-MRI. Materials and Methods: This study population was retrospectively selected from patients with intracranial stenosis who underwent intracranial HR-MRI between January 2016 and January 2017, from whom all of the plaque features were extracted using CMR Tools and Image J software. Statistical analysis was performed using a logistic regression model. Results: A total of 133 plaques were identified in the 133 patients (mean age 58.5±11.4 years), of which 75 patients were considered with acute ischemic stroke and 58 patients were asymptomatic. T1 images would have a higher sensitivity to predict the vulnerability of atherosclerotic plaques by the quantitative histogram analysis compared with T2 and T1-enhancement images. Multiple logistic regression analysis showed that MLA (OR=1.301, 95% CI, 1.036—1.633), IPH (OR=12.440, 95% CI, 1.551—99.780) and CV (OR=3.476, 95% CI, 1.513—7.985) were important predictors to define symptomatic plaques. Both the morphological and histogram features had been combined to classify the intracranial atherosclerotic plaques was better than the method on the single way, where the area under the curve (AUC) of ROC curve was 0.801. Conclusions: This study demonstrated that quantitative histogram analysis based on T1WI without enhancement could help distinguish acute symptomatic from asymptomatic plaques in intracranial atherosclerosis, and it is better than traditional method to differentiate acute symptomatic and asymptomatic intracranial atherosclerotic plaques.]]></description>
<pubDate>Tue,20 Mar 2018 00:00:00  GMT</pubDate>
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<title><![CDATA[Value of dynamic contrast-enhanced MRI in diagnosis of lung cancer and different types of benign lung nodules]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2018.03.006</link>
<description><![CDATA[Objective: To evaluate the value of dynamic contrast-enhanced MRI (DCE-MRI) in the differential diagnosis of lung cancer and different types of benign lung nodules. Materials and Methods: Twenty lung cancer (malignant group), 10 active infections (active infection group) and 13 benign nodules (benign group) with pathology or clinical follow-up proven were enrolled in the study and underwent routine MRI and DCE-MRI scan. The signal intensity-time (SI-T) curves with ROI were obtained at EWS post-processing workstation and the curves were defined asⅠ, Ⅱ, Ⅲ, Ⅳ, types. The hemodynamic parameters of the three groups were calculated and analyzed. The statistical differences of the SI-T curve types and the parameters among the three groups were compared. The threshole of diagnosis of lung cancer was determined by ROC curve analysis. Results: The distribution of the curve types of the three groups were significantly different (P=0.02). Curve typesⅠand Ⅱ were considered positive for malignancy. It was found that the Wash-in for the malignant group was significantly higher than that for the benign group and significantly lower than that for the active infection group (P=0.034, 0.012). The TTP for the malignant group was significantly lower than that for the benign group and significantly higher than that for the active infection group (P=0.018, 0.041). With 54.2 and 30.5 as the threshold Wash-in for distinguishing lung cancer from active infection and benign nodules, the sensitivity, specificity and accuracy was 80.05%, 70.57%, 74.42% respectively. Conclusions: The SI-T curves and the hemodynamic parameters of DCE-MRI may be a useful tool in differentiating lung cancer from active infection nodules,as well as benign nodules.]]></description>
<pubDate>Tue,20 Mar 2018 00:00:00  GMT</pubDate>
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<title><![CDATA[Dynamic contrast enhanced MRI for pancreatic perfusion in acute pancreatitis]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2018.03.007</link>
<description><![CDATA[Objective: To study dynamic contrast enhanced MRI (DCE-MRI) for the normal pancreas and acute pancreatitis (AP). Materials and Methods: The institutional review board approved the study, written informed consent was obtained. Twenty patients without any pancreatic disorders (control group) and forty five patients with clinically proved AP were recruited in this study. All patients had performed MRI with T1WI, T2WI, fat suppression T2WI sequences, multiple flip angle T1WI-LAVA and T1WI-LAVA dynamic contrast enhanced scan sequence. The OmitkDCEMRITool of Omni-Kinetics Version V2.0.10 (GE) was used to analyze the multiple flip angles T1WI-LAVA and T1WI-LAVA dynamic contrast enhanced imagings. The Ktrans, Vp and AUC values were measured in both AP group and Control group. The perfusion parameters of the head, body and tail of normal pancreas were compared by using the Wilcoxon singned-rank test, and the perfusion parameters of AP group and Control group were compared by Wilcoxon rank sum test. Results: The Ktrans, Vp and AUC values of AP were (0.417, 0.132—0.746) ml/min, (0.058, 0.028—0.12) and (4.467, 3.594—7.447), respectively. The Ktrans, Vp and AUC values of normal pancreas were (0.762, 0.389—0.918) ml/min, (0.222, 0.111—0.347), (6.597, 4.646—9.226), respectively. The Ktrans, Vp and AUC values of AP were lower than those of control group (all P＜0.05). The Vp value of normal pancreas was no statistically significant difference among the head, body and tail (all P＞0.05). The Ktrans and AUC values of normal pancreas were statistically significant difference between the head and body (all P＜0.05), as well as between the head and tail (all P＜0.05). But no statistical difference was found between the body and tail (all P＞0.05). Conclusions: DCE-MRI can quantify the microcirculation perfusion of the pancreas with noninvasive and no radiation, and lay the foundations of theory and practice for further study the AP perfusion.]]></description>
<pubDate>Tue,20 Mar 2018 00:00:00  GMT</pubDate>
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<title><![CDATA[Feasibility of non-contrast-enhanced magnetic resonance angiography for evaluating portal venous hemodynamics]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2018.03.008</link>
<description><![CDATA[Objective: To investigate the feasibility of non-contrast-enhanced magnetic resonance angiography (NCE-MRA) using spatial labeling with multiple inversion pulses (SLEEK) in evaluating portal venous hemodynamics. Materials and Methods: Twenty-five patients with portal hypertension were examined with SLEEK-MRA and color Doppler ultrasonography (CDUS) respectively. SLEEK-MRA series were performed with different blood suppression inversion time (BSP TI) settings of 600 ms, 900 ms, 1200 ms and 1500 ms. Portal venous branching grade of SLEEK-MRA series were analyzed with CDUS-measured hemodynamics using Spearman rank correlation coefficient (rs). Patients were divided into 2 groups depending on portal venous velocity and portal venous branching grades as well as BSP TI settings of the 2 groups were compared. Results: At all BSP TI settings, branching grade scores of the left portal vein (LPV) and the right portal vein (RPV) were of statistically significant correlation with CDUS-measured flow velocity of LPV and RPV respectively. The correlation coefficient of LPV at each BSP TI settings (600, 900, 1200, 1500 ms) were 0.534, 0.408, 0.563, 0.621 respectively. The correlation coefficient of RPV at each BSP TI settings were 0.655, 0.578, 0.699, 0.641 respectively. For patients of obviously decreased portal flow velocity, branching grade scores were significantly lower than patients of normal or slightly decreased portal flow velocity. To reach the same portal venous branching visualization, patients of obviously decreased portal flow velocity need to apply with higher BSP TI settings. While most of patients of normal or slightly decreased portal flow velocity applied 900 ms to reach grade 6, 42.9% of patients of obviously decreased portal flow velocity could not reach it even applied a BSP TI setting of 1500ms. Conclusions: SLEEK-MRA has the potential to suggest portal venous flow changes with high-quality morphological visualization of portal vein imaging simultaneously. It is feasible for SLEEK-MRA to provide hemodynamical information.]]></description>
<pubDate>Tue,20 Mar 2018 00:00:00  GMT</pubDate>
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<title><![CDATA[The application value of diffusion kurtosis imaging and histogram analysis for assessing preoperative T stages of rectal cancer]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2018.03.009</link>
<description><![CDATA[Objective: To explore the value of diffusion kurtosis imaging (DKI) and histogram analyses for assessing preoperative T stages of rectal cancer. Materials and Methods: Fifty patients were enrolled confirmed rectal adenocarcinoma by pathology from our hospital. The value of DKI parameters and histogram metrics for assessing preoperative T stages in rectal cancer were retrospectively analyzed. Results: (1) In all, there were 19 early rectal cancer (T1-2) and 31 advanced cancer (T3-4). ADC-10th and ADC-25th were significantly higher in T1-2 than in T3-4 rectal cancer [the ADC value were (0.65±0.08)×10-3 mm2/s vs (0.58±0.11)×10-3 mm2/s, (0.73±0.11)×10-3 mm2/s vs (0.65±0.11)×10-3 mm2/s, and the P value were 0.035, 0.024 respectively]. (2) D-10th and D-25th were also significantly higher in T1-2 than in T3-4 rectal cancer [the D value were 0.96±0.19×10-3 mm2/s vs 0.84±0.16×10-3 mm2/s, 1.15±0.27×10-3 mm2/s vs 0.99±0.18×10-3 mm2/s, and the P value were 0.017, 0.044 respectively]. (3) K value and its histogram metrics showed no statistically significance between T1-2 and T3-4. (4) D-10th had the biggest area under the curve (AUC 0.799) of all the parameters, the sensitivity and specificity were 84.2%, 61.3% respectively. (5) DKI combined with traditional MRI had an accuracy of 68% to assess the lymph node of rectal cancer. Conclusions: DKI and its histogram metrics are quite valuable for assessing preoperative T stages of rectal cancer, and D-10th has the highest diagnostic efficiency.]]></description>
<pubDate>Tue,20 Mar 2018 00:00:00  GMT</pubDate>
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<title><![CDATA[Value of intravoxel incoherent motion diffusion weighted imaging in endometrial cancer for estimating histological grade and myometrial invasion]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2018.03.010</link>
<description><![CDATA[Objective: To investigate the utility of intravoxel incoherent motion (IVIM) imaging in assessing pathological grade and myometrial invasion of endometrial cancer (EC) preoperatively. Materials and Methods: Forty-three consecutive patients with EC confirmed by surgery and pathology underwent IVIM DWI with 12 b values preoperatively. IVIM parameters including apparent diffusion coefficient (ADC), true diffusivity (D), perfusion-related diffusivity (D*) and perfusion fraction (f) were measured and compared among different pathological grades (Grade1, 2, 3), and between the depth of myometrial invasion. Spearman correlation was performed to analyze the association of these parameters with the histological grades and the depth of myometrial invasion. ROC curve was used to determine diagnostic efficiency. Results: The ADC, D and f values were negatively associated with tumor grades of EC (r=-0.604, -0.448 and -0.428, P=0.000, 0.002 and 0.004). There were significant difference of ADC values between G1 and G3 of EC, between G2 and G3 of EC (P=0.000 and 0.009). The D and f values of ECwere significantly lower in the G3 than G1 (P=0.01). No statistical difference of the D* existed between those three groups (P=0.071). Area under the curve (AUC) was largest for ADC in distinguishing G3 from G1-2 (AUC=0.825, 95%CI: 0.679—0.924; P=0.0001), and with the cut-off of 0.796×10-3 mm2/s, the sensitivity, specificity and accuracy were 71.43%, 89.66% and 83.72%, respectively. All these parameters were negatively correlated with the depth of myometrial invasion. The ADC, D, D* and f values were significantly lower in the deep myometrial invasion than the superficial myometrial invasion. The D value showed the highest diagnostic performance in recognizing deep myometrial invasion (AUC=0.879, 95%CI: 0.744—0.959, P=0.0001), and using the cut-off of 0.631×10-3 mm2/s,
the sensitivity, specificity and accuracy were 100%, 76.67% and 83.72%, respectively. Conclusions: IVIM DWI parameters may be a promising biomarker for endometrial cancer in predicting histological grade and the depth of myometrial invasion preoperatively which could be helpful in treatment planning and prognosis evaluation.]]></description>
<pubDate>Tue,20 Mar 2018 00:00:00  GMT</pubDate>
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<title><![CDATA[Value of quantitative dynamic contrast-enhanced MRI in the evaluation of bone marrow perfusion in the adult hip]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2018.03.011</link>
<description><![CDATA[Objective: To evaluate the bone marrow perfusion in the adult hip at quantitative dynamic contrast-enhanced MRI (DCE-MRI) with regard to sex, age and skeletal site. Materials and Methods: This retrospective study includes 168 patients who underwent DCE-MRI. Quantitative parameters Ktrans, Kep, Ve were calculated in the acetabulum, femoral epiphysis and metaphysis. The parameters at different regions were compared by Kruskal-Wallis test. The correlations between age and quantitative parameters in different sites were calculated using Spearman rank coefficient analysis in men and women respectively. Patients were then stratified into two groups, those 50 years or younger and those older than 50 years old. Perfusion parameters in different locations between different genders were compared by using the Wilcoxon signed-rank tests in each age group. Results: This study includes 168 patients (88 men, mean age, 59.97 years [age range, 22—89 years], 80 women, mean age 57.69 years [age range, 21—85 years]). A significant difference (P＜0.05) in Ktrans, Kep, Ve was found among different skeletal sites. There was a significant correlation between age and Ktrans, Kep, Ve of the acetabulum (Spearman rs=-0.532, -0.476, -0.319 in men and -0.566, -0.387, -0.406 in women respectively), between age and Ve of femoral epiphysis in men (rs=-0.152), between age and Kep of femoral epiphysis in women (rs=0.282), between age and Ktrans, Kep of femoral metaphysis in women (rs=-0.200, -0.297), P＜0.05. The Ktrans, Kep, Ve of the acetabulum and femoral metaphysis were significantly different between males and females in patients younger than 50 (P＜0.05). Males and females revealed no difference for Ve of the acetabula and femoral epiphysis in patients older than 50 years old (P＞0.05), while other parameters were statistically different (P＜0.05). Conclusions: DCE-MRI is a technique that acquires perfusion parameters in the hip non-invasively quantitatively. Bone marrow perfusion parameters in the adult hip are influenced by location, gender and age.]]></description>
<pubDate>Tue,20 Mar 2018 00:00:00  GMT</pubDate>
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<title><![CDATA[Advances in functional magnetic resonance imaging and analysis methods in trigeminal neuralgia]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2018.03.013</link>
<description><![CDATA[Trigeminal neuralgia is characterized by severe, brief, stabbing, “electric shock-like” recurrent pain attacks felt in one or more divisions of trigeminal nerve innervation areas. The pathogenesis of TN includes “Peripheral pathogenic theory” and “Central patheogenic theory”. “Neurovascular compression” is representative in former, which leads to nerve demyelination and conduction disorders. The latter emphasizes the importance of “the Central Nervous System” in the process of pain generation and modulation. The latest progresses in the field of diffusion tensor imaging (DTI), the voxel-based morphometry (VBM) and resting-state functional magnetic resonance imaging (rs-fMRI) were reviewed in this paper.]]></description>
<pubDate>Tue,20 Mar 2018 00:00:00  GMT</pubDate>
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<title><![CDATA[Research advances of functional MRI in placenta]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2018.03.014</link>
<description><![CDATA[The evaluation of placental function is essential to the understanding and diagnosis of pregnancy complications. In recent years, functional MRI is applied more and more in both animal models and clinical research in placenta, which could provide useful information on physiological functions of placenta, including vascularization, oxygenation, metabolism and diffusion within tissues. Functional MRI shows great research value and clinical applying foreground.]]></description>
<pubDate>Tue,20 Mar 2018 00:00:00  GMT</pubDate>
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