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<title>Chinese Journal of Magnetic Resonance Imaging RSS feed</title>
<link>http://med-sci.cn/cgzcx/en/contents_list.asp?issue=202103</link>
<language>zh-cn</language>
<copyright>An RSS feed for Chinese Journal of Magnetic Resonance Imaging</copyright>
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<title><![CDATA[Clinical and MRI analysis of hepatic and cerebral hepatolenticular degeneration]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2021.03.001</link>
<description><![CDATA[Objective: To investigate the disparity of the imaging features, fundus examination and laboratory examination between hepatic and cerebral hepatolenticular degeneration [Wilson disease (WD)]. Materials and Methods: The imaging features and clinical data, presentation, laboratory examinations of 89 patients with hepatolenticular degeneration diagnosed by gene test in the first affiliated hospital of army medical university hospital between 2009—2019 were collected and analyzed retrospectively. MRI abnormalities were rated using standardized methods. Comparison of clinical measures and imaging scores between different types of hepatolenticular degeneration patients were performed. Results: There was no significant difference in the positive rate of KF between brain type and liver type (P=0.946＞0.05), but the content of copper and ceruloplasmin in patients of brain type were significant lower than those in patients of liver type (P＜0.001). The abnormal signal rate of brain MRI except pallidum, thalamus and cerebellum in patients of brain type was higher than that in patients of liver type (P=0.043, 0.013＜0.05). There was no significant difference between the two types of patients in the abnormal signal range of globus pallidus and thalamus (P＞0.05), while the cumulative score of patients with brain type was significantly higher than that of patients with liver type (P＜0.05); there was no statistical significance between the two types of patients in the abnormal signal range and cumulative score of cerebellar region (P=0.779＞0.05). The T2 sequence range and degree total score of brain MRI in patients with brain type hepatolenticular degeneration were positively correlated with the onset time (r=0.315, P= 0.038), but not in patients with liver type. Conclusions: Brain images of WD patients with simultaneous involvement of basal ganglia and brainstem are characteristic imaging findings both in patients of liver and brain types. The intracranial abnormal signal ratio, onset time, and the range and extent of intracranial lesions in patients brain types were higher than those in patients with liver type. Quantitative evaluation of T2 sequences is a potential evaluation method for the pathological stages and extent of the brain in WD patients.]]></description>
<pubDate>Sat,20 Mar 2021 00:00:00  GMT</pubDate>
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<title><![CDATA[Clinical research of NODDI technology in deep brain nucleus of Parkinson's disease]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2021.03.002</link>
<description><![CDATA[Objective: To investigate microstructural changes of gray matter nucleus in people with Parkinson's Disease (PD) by neurite orientation dispersion and density imaging (NODDI). Materials and Methods: Thirty-six PD patients and 26 healty volunteers underwent MRI and were divided into the case group and the control group, NODDI images were analyzed and processed. Intracellular volume fraction (Vic) and orientation dispersion index (ODI) from the case group were separately compared with those from the control group, and receiver operating characteristic curve (ROC) evaluated the diagnostic efficiency of different nucleus. Results: The Vic values of left substantia nigra (P＜0.001), thalamus (P=0.003), right caudate nucleus head (P=0.002), putamen (P＜0.001), globus pallidus (P＜0.001), substantia nigra (P＜0.001), red nucleus (P＜0.001) and thalamus (P=0.006) in PD patients were significantly different from those in the control group. Compared with the control group, the ODI values of left substantia nigra (P＜0.001), right caudate nucleus head (P=0.038), putamen (P=0.001), globus pallidus (P=0.023) substantia nigra (P＜0.001) and red nucleus (P=0.023) in PD patients showed significantly difference. Meanwhile, the ROC curve showed that area under curve (AUC) of the Vic values for PD's diagnosis were respectively 0.861, 0.788, 0.852, 0.843 in right substantia nigra, red nucleus, globus pallidus and putamen. In addition, the AUC of the combined diagnosis of substantia nigra and globus pallidus, substantia nigra and putamen were separately 0.925, 0.921. Conclusion: NODDI can qualitatively distinguish between PD patients and healthy volunteers, and quantitatively analyze microstructural changes of deep brain nucleus. And the joint diagnosis of nucleus can obtain higher value, which is helpful for PD's clinical diagnosis.]]></description>
<pubDate>Sat,20 Mar 2021 00:00:00  GMT</pubDate>
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<title><![CDATA[Preliminary study on comparing the ReHo features of resting-state functional MRI between the treatment-resistant and non-treatment-resistant depression]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2021.03.003</link>
<description><![CDATA[Objective: To explore the brain function difference between the treatment-resistant depression (TRD) and non-treatment-resistant depression (nTRD), the local consistency ReHo (regional homogeniety) method was used to analyze the resting state functional magnetic resonance imaging data,and then the result of functional brain imaging was correlated with the scores of the clinical symptoms' scales. Materials and Methods: The study was recruited with 27 TRD patients, 22 nTRD and 22 healthy controls. All subjects were conducted with the resting state fMRI. The fMRI data was processed by DPARSF 5.0. The clinical symptoms were also collected and evaluated with the scales of Depression, Anxiety, and Rumination Response. The one way ANOVA (analysis of variance) was used to test the differences in ReHo among the three groups. The ReHo values of brain areas were correlated with the clinical scales' scores. Results: There was no significant difference in demographic data and clinical symptom scores between the two groups of depression patients. However, significant differences in ReHo values were found in the left superior temporal gyrus and multiple brain areas on the right cerebrum. Compared with the nTRD group, the TRD group showed higher ReHo values in the left superior temporal gyrus and the right posterior cerebellum, and lower in the right orbitofrontal gyrus. The ReHo values of the right upper /middle frontal gyrus and orbital frontal gyrus in the TRD group were positively correlated with the RRS scale scores, respectively (P=0.015, r=0.46), (P=0.018, r=0.44). Conclusions: Even though there are the similar scale scores of the symptoms between the TRD and non-TRD, an apparent difference exists of brain function ReHo value. Therefore, the physiopathology of TRD involves more brain regions, including emotion, cognition, primary sensory center, etc., which are significantly related to clinical symptoms.]]></description>
<pubDate>Sat,20 Mar 2021 00:00:00  GMT</pubDate>
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<title><![CDATA[DTI quantitative evaluation of brain microstructural changes after melodic intonation therapy in the treatment of Broca aphasia]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2021.03.004</link>
<description><![CDATA[Objective: To explore the characteristics of brain fiber structure changes in Broca aphasia treated with melody intonation therapy (MIT) through information of language related fiber structure provided by diffusion tensor imaging (DTI). Materials and Methods: A total of 37 patients with Broca aphasia after stroke admitted to the First affiliated Hospital of Xinjiang Medical University between January 2019 and June 2020 were enrolled. Divided the patients into two groups: control group (n=19) were treated with routine speech therapy, experimental group (n=18) were treated with MIT and routine speech therapy. Patients in both groups underwent DTI before and 2 months after the therapy. The fractional anisotropy (FA) of bilateral Broca area and arcuate fasciculus were measured before and after the therapy in experimental group. FA of both Broca area and arcuate fasciculus before and after treatment were compared between the experimental group and the control group. Results: Comparison of experimental group before and after therapy showed: FA of both Broca and arcuate fasciculus were statistically significant (Bilateral arcuate fasciculus and left Broca area P＜0.001, Right Broca area P=0.008). There was no significant difference in FA of bilateral Broca area and arcuate fasciculus between the experimental group and the control group before therapy (right Broca P=0.154, left Broca P=0.228, right arcuate fasciculus P=0.361, left arcuate fasciculus P=0.135). Two months after thrapy, between the experimental group and the control group, FA of right arcuate fasciculus were statistically significant (P=0.008). There was no significant difference in FA between left arcuate fasciculus and bilateral Broca (right Broca P=0.138, left Broca P=0.093, left arcuate fasciculus P=0.259). Conclusions: After MIT intensive rehabilitation therapy for patients with Broca aphasia, the FA of the right arcuate fasciculus increased, suggesting that the therapeutic mechanism of MIT is related to the structural changes of the right arcuate fasciculus.]]></description>
<pubDate>Sat,20 Mar 2021 00:00:00  GMT</pubDate>
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<title><![CDATA[The value of minimum apparent diffusion coefficient value in differential diagnosis of giant cell glioblastoma and glioblastoma]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2021.03.005</link>
<description><![CDATA[Objective: To explore the value of minimum apparent diffusion coefficient (ADCmin) value in the differential diagnosis of intracranial glioblastoma and giant cell glioblastoma. Materials and Methods: MRI data of 11 cases of giant cell glioblastoma and 19 cases of classical glioblastoma confirmed by surgery and pathology were retrospectively analyzed. All patients underwent MR plain scan, enhancement and DWI before surgery. The ADCmin value of the tumor parenchyma was measured, and the difference between the two was compared, and the diagnostic efficacy was analyzed by ROC curve. Results: The ADCmin value of giant cell glioblastoma was (0.989± 0.104)×10－3 mm2/s, and the ADCmin value of glioblastoma was (0.837±0.111)×10－3 mm2/s. The difference was statistically significant (t= 3.671, P=0.001). The ROC curve showed that the AUC was 0.852 (P=0.002). Taken ADCmin value=0.880×10－3 mm2/s as the threshold, the sensitivity was 90.9%, and the specificity was 68.4%. Conclusions: ADCmin value has high clinical application value in differential diagnosis of giant cell glioblastoma and classical glioblastoma, and can be used as an effective supplement for routine MR examination.]]></description>
<pubDate>Sat,20 Mar 2021 00:00:00  GMT</pubDate>
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<title><![CDATA[Clinical and imaging characteristics of cryptococcal intracranial infection in patients with acquired immune deficiency syndrome]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2021.03.006</link>
<description><![CDATA[Objective: To investigate the clinical and imaging characteristics of cryptococcus meningitis (CM) in patients with acquired immunedeficiency syndrome (AIDS), thus to improve the diagnosis of this disease. Materials and Methods: The clinical and imaging data of 20 AIDS patients with CM were retrospectively analyzed. Results: Among the 20 cases, there were 17 males and 3 females. The age were ranged from 25 to 63 (median age 40.4); the CD4 counts were range from 1 to 162/μL (median number 26/μL). In cerebrospinal fluid, glucose was (2.45±1.090) mmol/L, and chlorine content was (119.86±4.669) mmol/L. Clinical symptoms included headache (80%), nausea and vomiting (15%), disturbance of consciousness (5%), blurred vision (5%) and fever (5%), 10% cases have no symptoms. On MRI, 11 cases were mainly characterized by dilated perivascular spaces (PVS) and pseudocyst, 6 cases were mainly characterized by meningitis/meningoencephalitis, 1 case presented both dilated PVS and meningitis/meningoencephalitis, 1 case presented with meningitis/meningoencephalitis and miliary nodules, 1 case presented other imaging feature. Conclusions: The most common clinical symptom of AIDS patients with CM was headache, followed by nausea and vomiting. Imaging features included dilated PVS and pseudocyst.]]></description>
<pubDate>Sat,20 Mar 2021 00:00:00  GMT</pubDate>
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<title><![CDATA[Comparison of conventional cholangiopancreatography and compressed sensing cholangiopancreatography in the display of biliary dilatation and pancreatic duct dilatation]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2021.03.007</link>
<description><![CDATA[Objective: To compare the image qualities of conventional cholangiopancreatography and compressed-sensing cholangiopancreatography imaging for biliary dilatation imaging and bile duct structure display for clinical selection of more suitable imaging methods. Materials andMethods: A retrospective study of 37 patients with pancreaticobiliary duct dilatation in Henan Provincial People's Hospital from July 2019 to December 2019 was investigated. Patients underwent conventional MRCP and CS-MRCP on a 1.5 T scanner (MAGNETOM Sempra, Siemens). A 5-point scale was used to evaluate image quality. One radiologist with more than 5 years of clinical experience and another one with 2 years of clinical experience scored the image quality. The results were analyzed using SPSS software paired t test. Results: There is no statistical difference in overall image quality, bile duct dilatation and pancreatic duct dilatation display on both conventional MRCP and CS-MRCP (P＞0.05). The scores of dilated bile ducts are higher than the overall image quality score and pancreatic duct dilatation score. There was no statistical difference in the image scores of bile duct dilatation caused by stones and bile duct dilatation caused by masses. Conclusions: There is no significant difference in image quality between compressed sensing cholangiopancreatography and conventional cholangiopancreatography, however, compressed sensing cholangiopancreatography can effectively shorten the imaging time and reduce respiratory motion artifacts.]]></description>
<pubDate>Sat,20 Mar 2021 00:00:00  GMT</pubDate>
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<title><![CDATA[To investigate the impact of first pass reperfusion on functional outcome of acute stroke based on hypoperfusion intensity ratio]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2021.03.008</link>
<description><![CDATA[Objects: To investigate the impact of first pass reperfusion (FPR) on functional outcome of acute stroke with different collateral circulation after endovascular thrombectomy (EVT). Materials and Methods: A total of 180 acute stroke patients in our hospital were enrolled retrospectively. All patients underwent MR perfusion imaging and EVT therapy. Hypoperfusion intensity ratio (HIR) was used to evaluate collateral circulation. Good collateral circulation was defined as HIR＜0.4 and poor collateral circulation was defined as HIR≥0.4. FPR was defined as achieving modified Thrombolysis in Cerebral Infarction (mTICI) 2b-3 after a single pass of the device. Statistical methods were performed to analyze the impact of FPR on the outcome in acute stroke with different collateral circulation after EVT therapy. Results: For patients with HIR≥0.4 (n=72), compared with non-FPR group (n=30), the mortality rate at 3 months (11.90% vs. 33.33%) was lower and good functional outcome at 3 months (59.52% vs. 33.33%) was higher in FPR group (n=42). For patients with HIR＜0.4 (n=108), the mortality rate at 3 months and good functional outcome at 3 months had no significant differences between two group (P＞0.05). Logistic regression analysis showed that FPR was an independent predictor of good functional outcome in acute stroke patients with HIR≥0.4 (OR=2.281, 95% CI: 1.419—5.286; P=0.018). While FPR had no significant difference in predicting the good functional outcome in acute stroke patients with HIR＜0.4 (OR=1.693, 95% CI: 0.596－4.798; P=0.319). Conclusions: The effect of FPR on functional outcome is highly dependent on collateral circulation. When the collateral circulation is poor (HIR≥0.4), the effect of FPR on functional outcome is more prominent.]]></description>
<pubDate>Sat,20 Mar 2021 00:00:00  GMT</pubDate>
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<title><![CDATA[To explore the outcome differences in acute ischemic stroke with different time windows after mechanical thrombectomy]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2021.03.009</link>
<description><![CDATA[Objective: We aimed at studying the outcome in acute ischemic stroke with different time windows after mechanical thrombectomy if they present with a diffusion-weighted imaging (DWI) -perfusion-weighted imaging (PWI) mismatch. Materials andMethods: In this retrospective study, 200 acute stroke patients who received mechanical thrombectomy in our hospital were enrolled. All patients ≤24 hours of symptom onset and underwent MR examination before and after therapy. The vascular recanalization was assessed by mTICI grade. DWI volume, PWI abnormal volume, the functional outcome at 3 months (mRS) and other clinical data were collected. According to the median time window, the patients were divided into early time window and late time window group. Statistical analysis was used to analyze the outcome differences in acute stroke with different time windows. Results: According to the median time window, patients were divided into early time window group (≤300 min; n=118) and late time window group (＞300 min; n=82); There was no significant difference in DWI infarct volume on admission and DWI-PWI mismatch volume between two groups (P＞0.05). However, compared with late time window group, DWI infarct growth volume [11 mL (1—45 mL) vs. 29 mL (3—87 mL)] in early time window group was smaller and the proportion of good functional outcome was higher (62.71% vs. 39.02%), the differences showed statistically significant (t=-2.371, P=0.027; χ2=10.898, P=0.001). Multivariable logistic analysis demonstrated that vascular recanalization (OR, 3.75; 95% CI: 1.43—10.86; P=0.008), DWI infarct growth volume (OR, 0.73; 95% CI: 0.58—0.95; P=0.017) and time window (OR, 0.41; 95% CI: 0.11—0.79; P=0.005) were independently associated with functional outcome. Conclusions: Outcome of acute stroke patients with DWI-PWI mismatch is time-dependent. Early time window, complete vascular recanalization and small DWI infarct growth volume are beneficial to the good functional outcome in acute stroke patients after mechanical thrombectomy.]]></description>
<pubDate>Sat,20 Mar 2021 00:00:00  GMT</pubDate>
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<title><![CDATA[The value of diffusion-weighted imaging of single index, double index and stretch index models in the differential diagnosis of orbital benign and malignant tumors]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2021.03.010</link>
<description><![CDATA[Objective: To explore the value of single index, double index and stretch index model DWI in the differentiation of orbital benign and malignant tumors. Materials and Methods: Fifty-one patients with orbital tumors confirmed by surgery and pathology from January 2019 to December 2019 were enrolled. They underwent 3.0 T conventional magnetic resonance and multi-b value DWI examination before surgery. Among them, 26 were benign and 25 were malignant. Use GE ADW4.6 Functiontool post-processing software to measure the apparent diffusion coefficient (ADC) value of the single exponential model, the slow apparent diffusion coefficient (ADCslow) value, the fast apparent diffusion coefficient (ADCfast), perfusion fraction (f) value of the double exponential model, and the distributed diffusion coefficient (DDC) value、 the heterogeneity of intravoxel diffusion (α) value of stretch index model, compare the difference of each parameter value. Receiver operating characteristic curve (ROC) was used to evaluate the effectiveness of statistically different parameters in the differential diagnosis of orbital benign and malignant. Results: ADC, ADCslow, DDC and α values were significantly different in the differential diagnosis of benign tumors and malignant tumors (P＜0.05). Among them, the area under the receiver operating characteristic curve of DDC and ADCslow was the largest, respectively 0.84 and 0.81, the diagnostic threshold was 1.15×10－3 mm2/s (sensitivity, 79.20%; specificity, 92.60%) and 0.60×10－3 mm2/s (sensitivity 87.50%; specificity 66.70%). Conclusions: Diffusion weighted imaging with double index and stretch index models provides more information for the differential diagnosis of orbital tumors from benign and malignant. Compared with the ADC value generated by traditional single index DWI, ADCslow and DDC have greater advantages in the differential diagnosis of benign and malignant orbital tumors. The combination of ADCslow, DDC, and α has the highest diagnostic efficiency.]]></description>
<pubDate>Sat,20 Mar 2021 00:00:00  GMT</pubDate>
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<title><![CDATA[A comparative study on the evaluation of cardiac function in patients with acute myocardial infarction using compressed sensing cardiac cine imaging compared with traditional cardiac cine imaging]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2021.03.011</link>
<description><![CDATA[Objective: To investigate the advantage and value of compressed sensing cardiac cine imaging compared with traditional cardiac cine imaging in evaluation of cardiac function after acute myocardial infarction. Materials and Methods: Thirty patients with ST-segment myocardial infarction (STEMI) myocardial infarction after percutaneous coronary intervention (PCI) were scanned with United imaging UMR 780 3.0 T MRI, the uCS-Cine sequence based on compressed sensing technology, and the traditional sequence based on balanced steady-state free precession cardiac cine sequence (standard-Cine). The 8-slice images covered the apex to the bottom of the heart. The uCS-Cine whole heart scan was completed by one breath holding. Scanning parameters: slice thickness 8mm, interval 4 mm, TR/TE=2.73/1.36 ms, TA=12.7 s. The standard-Cine was performed with 8 breath holding. Scanning parameters: slice thickness 8 mm, interval 4 mm, TR/TE=2.82/1.30 ms, TA=150 s. Two experienced radiologists evaluated the signal to noise ratio (SNR) of cardiac muscle, and the display of anatomical structures, artifacts and whether they could meet the needs of diagnosis on 8 layers (apex as the first layer and bottom as the eighth layer). The cardiac function of the two sequences was analyzed by uWS-780 workstation. The results were evaluated by SPSS 21.0 software by paired rank sum test. Results: The results of cardiac function analysis of 30 patients showed that there was no significant difference in left ventricular ejection fraction (LVEF) and left ventricular end systolic volume (LVESV) between uCS-Cine and standard-Cine sequences (P＞0.05), while the standard-Cine of left ventricular end diastolic volume (LVEDV) was slightly larger than that of uCS-Cine (P＜0.05). In terms of the objective score of image quality, the SNR of cardiac muscle of standard-Cine in slice1-slice 8 was higher than that in uCS-Cine (P＜0.05), and in terms of subjective image quality score, compared with standard-Cine sequence, 8-layer short axis images covered from apex to bottom of heart. At slice1-slice6 level, image quality score was not statistically significant (P＞0.05), while in slice7-slice8 level, the subjective score of traditional standard-Cine was better than that of uCS-Cine, and the results were statistically significant (P＜0.05). Conclusions: Compared with the conventional standard-Cine, the uCS-Cine based on compressed sensing technology has no significant difference in heart function analysis and subjective score of image quality, and can greatly shorten the examination time, improve the success rate of examination, and has high clinical application value.]]></description>
<pubDate>Sat,20 Mar 2021 00:00:00  GMT</pubDate>
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<title><![CDATA[Image quality assessment on MR images of the prostate acquired in different diffusion weighted sequences]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2021.03.012</link>
<description><![CDATA[Objective: We aimed to compare the image quality among conventional diffusion-weighted imaging (DWI), ZOOMit DWI, and RESOLVE DWI sequences for prostate imaging and to optimize the strategy to obtain high-quality diffusion MRI. Materials and Methods: We retrospectively collected patients scanned with conventional DWI, ZOOMit DWI, and RESOLVE DWI imaging on the same scanner from April to october 2020, sixty patients were enrolled. The clarity, distortion, and artifacts of the images acquired in the three sequences were subjectively evaluated by two experience d radiologists. The outline of the prostate was manually delineated from the images by two experienced radiologists, and the SNR and CNR of the images were calculated. Differences in the subjective scores and objective parameters among the three sequences were compared. Results: The subjective scores of clarity, distortion, and artifacts have significantly difference among the three sequences (P＜0.05). ZOOMit DWI had the highest clarity and the lowest distortion and artifacts. The the SNR (b=50) and SNR (b=1400) have significantly difference among the three DWI techniques (P＜0.05). The CNR (b=50) of the three DWI sequences have no difference (P＞0.05). The right-left diameter and the ratio of the anterior-posterior diameter/right-left diameter have significantly difference among the three DWI techniques (P＜0.05). Conclusions: ZOOMit DWI sequence images were of higher quality. Therefore, ZOOMit DWI for prostate MRI is preferable for a better diagnosis.]]></description>
<pubDate>Sat,20 Mar 2021 00:00:00  GMT</pubDate>
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<title><![CDATA[Simultaneous multi-slice accelerated turbo spin echo imaging for the thigh muscle-an image quality analysis]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2021.03.013</link>
<description><![CDATA[Objective: To investigate the image quality of simultaneous multi-slice (SMS) accelerated fat-saturated (FS) T2WI turbo spin echo (TSE) magnetic resonance imaging protocol on the thigh muscle in comparison with parallel acquisition technique (PAT) accelerated FS T2WI TSE protocol. Materials and Methods: Twenty-seven subjects (19 healthy volunteers and 8 patients indicated for MRI examination for thigh muscle) were included in the research in total. All subjects were scanned using a 3.0 tesla MRI. Axial SMS accelerated FS T2WI TSE images and PAT accelerated FS T2WI TSE images of the thigh muscle were acquired for all the subjects. The scan time was 1 minute 20 seconds for SMS accelerated FS T2WI TSE image and 2 minutes 28 seconds for PAT accelerated FS T2WI TSE imaging respectively. Images were transferred to the workstation for further measurement. Signal intensity (SI) and noise (standard deviation, SD) of thigh muscle were measured on the same slice of two image sequences with SMS or PAT technique. The ROIs were located at the right medial vastus muscles, with an area of 1 cm2. Signal to noise ratio (SNR) was calculated accordingly. Subjective image quality was evaluated by 2 experienced radiologists independently using a 5-point scale. Paired student's t-test was used to compare the SD and SNR for the two groups of images. Wilcoxon signed ranks test was used to compare the subjective scores between the two groups. Statistically difference was considered while P＜0.05. The accordance between two different observers was investigated at the mean time. ICC values of more than 0.6 were considered good accordance between the two observers. Results: SMS accelerated FS T2WI TSE images showed significantly lower noises in comparison with PAT accelerated FS T2WI TSE images [(1.37±0.25) vs.(1.57±0.33); P=0.032]. There was no significant difference in SNR between two groups [(41.50±15.75) vs. (46.23±10.89); P=0.085]. The subjective image quality was of no significant difference by both of the two observers. Observer 1: [(3.81±0.68) vs. (3.93±0.50); P=0.317]; Observer 2: [(3.85±0.53) vs. (3.78±0.64); P=0.527]. Both groups of images showed good inter-observer accordance (SMS accelerated TSE images: ICC=0.75, conventional TSE images. ICC=0.782). Conclusions: By using a SMS accelerated FS T2WI TSE scan protocol in the imaging of the thigh muscle, compared with PAT accelerated FS T2WI TSE scan protocol, the acquisition time is reduced while the image quality remains similar.]]></description>
<pubDate>Sat,20 Mar 2021 00:00:00  GMT</pubDate>
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<title><![CDATA[Application of MR FLAIR in the diagnosis of ischemic stroke]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2021.03.014</link>
<description><![CDATA[Objective: To explore the application value of MR fluid-attenuated inversion recovery (FLAIR) sequence in the diagnosis of ischemic stroke. Materials and Methods: The clinical and MR imaging data of 150 patients with ischemic stroke treated in the hospital between January 2019 and March 2020 were retrospectively analyzed. According to the strength of FLAIR sequence hyperintense vessel sign (HVS), the patients were divided into group A (HVS＜5 points, n=53) and group B (HVS≥5 points, n=97). Clinical and imaging characteristics of the two groups were compared. The relationship between different HVS scores and the severity of neurological deficit and cerebral collateral circulation compensation grading, the relationship between Alberta Stroke Program Early CT Score (ASPECTS) on diffusion weighted imaging (DWI-ASPECTS) and cerebral infarction volume were analyzed. Results: There were no significant differences in gender, age, time from onset to MR examination, hypertension, diabetes, hyperlipidemia, smoking history and drinking history between the two groups (P＞0.05). The proportion of atrial fibrillation and National Institute of Health Stroke Scale (NIHSS) score of group A were higher than those of group B [39.62% vs. 20.62%, (14.65±2.54) points vs. (12.87±3.27) points] (P＜0.05). The grade of cerebral collateral circulation compensation and DWI-ASPECTS score were lower than group B [(1.86±0.45) vs. (2.27±0.64),(7.76±1.23) points vs. (8.25±1.34) points] (P＜0.05). The cerebral infarction volume of group A was larger than that of group B [(54.28±12.34) cm3 vs. (25.67±8.63) cm3] (P＜0.05). Conclusions: MR FLAIR is of value in the diagnosis of ischemic stroke. The higher the HVS score, the better the cerebral collateral circulation compensation, the milder the neurological deficit, and the smaller the cerebral infarction volume, which is of great significance for ischemic stroke.]]></description>
<pubDate>Sat,20 Mar 2021 00:00:00  GMT</pubDate>
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<title><![CDATA[Voxel-based gray matter volume study in patients with vestibular migraine]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2021.03.015</link>
<description><![CDATA[Objective: Voxel-based morphological analysis (VBM) was used to analyze the areas of gray matter changes in patients with vestibular migraine (VM), in order to provide new ideas in clinical pathophysiology. Materials and Methods: In strict accordance with the inclusion and exclusion criteria, 17 VM patients and 20 healthy controls were recruited. All subjects underwent three-dimensional T1-weighted image magnetic resonance (MRI) scans of the head. VBM was used to compare the brain gray matter volume of the two groups to explore local gray matter changes related to the pathophysiology of the disease.Results: Compared with the healthy control group, the gray matter volume of cerebellum, cerebellar vermis, anterior cingulate gyrus, middle orbital frontal gyrus, right temporal transverse gyrus, fusiform gyrus, right angular gyrus of VM patients decreased in VM group (P＜0.001, FEW correction). Conclusion: VM patients have multiple pain nociceptive and multisensory integrated brain regions with GM abnormalities. The central brain regions with volume changes may be involved in the pathophysiological mechanism of the disease.]]></description>
<pubDate>Sat,20 Mar 2021 00:00:00  GMT</pubDate>
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<title><![CDATA[CT, MRI misdiagnosis analysis of fat fibromatosis]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2021.03.016</link>
<description><![CDATA[Objective: To study the CT/MRI misdiagnosis reason on lipofibromatosis (LPF) and improve the preoperative diagnostic accuracy. Materials and Methods: Retrospectively analyzed the surgical pathology, the clinical and imaging data of 16-misdiagnosis cases of LPF and their preoperative CT/MRI. Results: Sixteen cases of LPF were all single, clinically characterized as bag piece which was slow-growing without tenderness. On CT, MRI, there were 14 (87.5%) cases, with thick density or the signal as priority. There were 15 (93.8%) cases, with fiber inserted into adipose tissue. And 8 (89%) cases, there was visible fiber reinforcement after enhanced scanning. And 7 cases, misdiagnosed as adipose tissue tumors because there was rich adipose tissue. Of which, 1 case was misdiagnosed as neurofibromatosis located in the subcutaneous, 1 case was misdiagnosed as fiber-sourced benign tumor, 1 case was hamartoma, 2 cases were misdiagnosed as a vascular tumor with no enhancement scanning, 4 cases were benign lesions. Conclusions: Although the CT and MRI signs of LPF obtain certain characteristic, but it is easily misdiagnosed as thick-density tumors or fibrous tumor or subcutaneous tumor which is described with thick density or signal priority with some fiber composition invasive growth, should consider the disease.]]></description>
<pubDate>Sat,20 Mar 2021 00:00:00  GMT</pubDate>
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<title><![CDATA[Correlation between DCE-MRI parameters/ADC and pathological molecular prognostic markers of breast cancer]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2021.03.017</link>
<description><![CDATA[Objective: To analyze the correlation between dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) parameters/apparent diffusion coefficient (ADC) and pathological molecular prognostic markers of breast cancer. Materials and Methods: The clinical data of 106 patients with breast cancer in our hospital were retrospectively analyzed. The differences in DCE-MRI parameters and ADC were compared between patients with the positive expressions and negative expressions of estrogen receptor (ER), progesterone receptor (PR), cell proliferation antigen Ki67 and androgen receptor (AR). The correlation between DCE-MRI parameters, ADC and expressions of ER, PR , Ki67 and AR was analyzed. Results: After Spearman rank correlation test, it was found that the positive expressions of ER, PR and AR were significantly negatively correlated with diameter and marginal burr (P＜0.05), and the positive expression of AR was also significantly positively correlated with time to peak (TTP) and ADC (P＜0.05). The positive expression of Ki67 was significantly positively correlated with diameter and marginal burr (P＜0.05), and was significantly negatively correlated with TTP and ADC (P＜0.05). Conclusions: DCE-MRI morphological parameters and TTP and ADC have a certain correlation with molecular biological markers of breast cancer, and they are beneficial to the prognosis of breast cancer.]]></description>
<pubDate>Sat,20 Mar 2021 00:00:00  GMT</pubDate>
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<title><![CDATA[Intravoxel incoherent motion imaging: research advances in brain tumors]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2021.03.019</link>
<description><![CDATA[Intravoxel incoherent motion (IVIM) imaging has become an important supplement to conventional brain tumor imaging in recent years. It can obtain the information of brain tumor diffusion and perfusion at the same time, which is conducive to a more comprehensive understanding of tumor physiological and pathological changes and tumor microenvironment. Recently, IVIM has achieved certain results in preoperative diagnosis, grading diagnosis, genotype monitoring and prognosis evaluation of glioma. This article will review the basic principle of IVIM and its clinical application in brain tumors.]]></description>
<pubDate>Sat,20 Mar 2021 00:00:00  GMT</pubDate>
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<title><![CDATA[Advances in imaging differentiation of pseudoprogression and recurrence of brain gliomas after treatment]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2021.03.020</link>
<description><![CDATA[Glioma, which originates from neuroepithelial cells, is the most common primary tumor in the brain. Its treatment is surgical resection and subsequent simultaneous radiotherapy and chemotherapy, but up to 30% of patients will develop new enhanced lesions in magnetic resonance imaging. This may not be the early tumor progression, but the pseudo progression caused by radiotherapy and chemotherapy Pseudoprogression, due to mild lesions and good prognosis, only needs symptomatic treatment, while tumor recurrence requires re-surgical treatment or other treatment options. If the tumor recurrence and false progression are misdiagnosed, it is likely to delay the best treatment time for patients, and eventually lead to ineffective diagnosis and treatment. Therefore, the correct distinction between recurrence and pseudoprogression of glioma patients is very important for the choice of clinical treatment. It is impossible for conventional magnetic resonance imaging to reliably distinguish PSP from EP. At present, some more advanced imaging methods are expected to identify them accurately.]]></description>
<pubDate>Sat,20 Mar 2021 00:00:00  GMT</pubDate>
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<title><![CDATA[Application progress of PET-MR imaging in Parkinson's disease]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2021.03.021</link>
<description><![CDATA[Parkinson's disease (PD) is a disease involving multiple systems and complicated etiology. Its clinical manifestations vary from person to person, and the progression of the disease varies. However, the reasons for such individual differences are still unclear. In recent years, positron emission tomography/magnetic resonance (PET-MR) imaging technology has developed rapidly and has gradually been widely used in the research of PD. It has played a huge role in elucidating the pathophysiology of PD, combining the metabolic and molecular information of PET with the structural and functional information of MR imaging will help us understand the abnormalities of the brain network of PD patients at an overall level and further broaden our understanding of the disease. This article reviews the application progress of PET-MRI in PD.]]></description>
<pubDate>Sat,20 Mar 2021 00:00:00  GMT</pubDate>
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<title><![CDATA[Research advances of magnetic resonance angiography in evaluating carotid arterystenosis]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2021.03.022</link>
<description><![CDATA[Carotid stenosis is an important cause of ischemic stroke. Early detection and early treatment can significantly reduce the fatality and disability rates. Magnetic resonance angiography plays an irreplaceable role in the quantitative assessment of carotid artery stenosis because of its advantages such as non-invasive, non-radiation and better resolution of soft tissue. This paper reviews the latest technology applications and research advances in the quantitative assessment of carotid artery stenosis using magnetic resonance angiography such as time of flight magnetic resonance angiography (TOF-MRA), contrast enhanced MRA (CE-MRA), zero echo time arterial spin aabeling MRA (zTE-ASL-MRA), four dimensional flow MRA (4D-Flow-MRA), black blood (BB), simultaneous noncontrast angiography and intraplaque hemorrhage imaging (SNAP), and rapid magnetic resonance imaging.]]></description>
<pubDate>Sat,20 Mar 2021 00:00:00  GMT</pubDate>
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<title><![CDATA[The application of cardiovascular magnetic resonance in risk stratification and prognosis evaluation in dilated cardiomyopathy]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2021.03.023</link>
<description><![CDATA[Dilated cardiomyopathy (DCM) represents a heterogeneous heart disease characterized by left ventricular dilatation and left ventricular systolic dysfunction, which could eventually result in heart failure, arrhythmia and sudden death and was also the main cause of heart transplantation. It is essential to accurately evaluate the degree of cardiac involvement, stratify disease risk, and identify high-risk individual who require close follow-up and intensive treatment in DCM patients. Cardiovascular magnetic resonance (CMR) is characterized by multi-modal and multi-parameter imaging. Using CMR cine sequences could accurately assess the morphological and functional abnormalities, whereas CMR-based histology and microstructure imaging could also provide more valuable prognosis information for DCM patients. This article will provide the overview of application progress of CMR in the risk stratification and prognosis assessment in DCM patients.]]></description>
<pubDate>Sat,20 Mar 2021 00:00:00  GMT</pubDate>
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<title><![CDATA[Application of cardiac magnetic resonance extracellular volume in hypertensive heart disease]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2021.03.024</link>
<description><![CDATA[Long-term increase in blood pressure can cause increased cardiac afterload, leading to hypertensive heart disease (HHD). The main changes of hypertensive heart disease are left ventricular hypertrophy and diffuse myocardial fibrosis. The extracellular volume (ECV) measured by cardiac magnetic resonance (CMR) T1 mapping is used as a non-invasive means to assess myocardial fibrosis and plays an important role in the diagnosis of hypertensive heart disease. The author discusses the pathophysiology of myocardial fibrosis in hypertensive heart disease, the characteristics of the extracellular volume of hypertensive heart disease, the change of extracellular volume after treatment, the extracellular volume and other techniques of cardiac magnetic resonance in hypertensive heart disease. The joint application of the company is reviewed.]]></description>
<pubDate>Sat,20 Mar 2021 00:00:00  GMT</pubDate>
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<title><![CDATA[Research progress of background parenchymal enhancement in breast magnetic resonance imaging]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2021.03.025</link>
<description><![CDATA[Breast cancer is the most common malignant tumor in women, which has high morbidity and mortality rates, and different molecular subtypes of breast cancer have different biological manifestations and clinical treatment prognosis. Therefore, the search for targeted and personalized imaging markers for diagnosis and treatment of breast cancer is a hot of current research. Background parenchymal enhancement (BPE) on breast magnetic resonance imaging (MRI) is an increasingly studied parameter that reflects the microvasculature of normal breast tissue, is influenced by many factors, and in the diagnosis and treatment prognosis of mammary gland disease has important diagnostic value. BPE has profound implications for women with or at risk of breast cancer, and may assess the curative effect of neoadjuvant chemotherapy of breast cancer. BPE shows promise as an imaging biomarker but many issues need to be addressed before it can be used either to determine screening strategy or the value of risk-reducing interventions. This review analyzes the influence factors of BPE and role in the diagnosis and treatment of breast cancer screening evaluation.]]></description>
<pubDate>Sat,20 Mar 2021 00:00:00  GMT</pubDate>
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<title><![CDATA[Application progress of MRI-based artificial intelligence in the diagnosis of liver fibrosis]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2021.03.026</link>
<description><![CDATA[Liver fibrosis is a necessary pathway for liver cirrhosis and severe complications and liver cancer in chronic liver diseases. Noninvasive diagnosis of liver fibrosis has been a hot topic in clinical research. With the continuous development of imaging technology and computer science, artificial intelligence techniques such as radiomics and machine learning can extract a large number of quantitative features from medical images which cannot be recognized by human eyes to achieve diagnosis prognosis evaluation and therapeutic prediction of the disease. Recently artificial intelligence technology has been deeply studied in liver fibrosis. This paper reviews the progress of clinical application of radiomics and machine learning based on MR imaging in diagnosis and staging of liver fibrosis.]]></description>
<pubDate>Sat,20 Mar 2021 00:00:00  GMT</pubDate>
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<title><![CDATA[The application of radiomics in intrahepatic cholangiocarcinoma]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2021.03.027</link>
<description><![CDATA[Radiomics is a technique to quantify the heterogeneity of tumors by extracting the texture, morphology and other quantitative features of lesions from images through various techniques. It has been gradually used in the diagnosis, biological behavior prediction and post-treatment evaluation of intrahepatic cholangiocarcinoma. However, there are still some limitations in intrahepatic cholangiocarcinoma radiomics, such as uneven data quality, lack of stability and repeatability of extracted features, and poor popularization. This article reviewed the application of radiomics in intrahepatic cholangiocarcinoma.]]></description>
<pubDate>Sat,20 Mar 2021 00:00:00  GMT</pubDate>
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<title><![CDATA[Advances in application of radiomics in colorectal cancer]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2021.03.028</link>
<description><![CDATA[In recent years, with the continuous development of image processing and computer technology, the use of imaging histological analysis methods for accurate preoperative evaluation of patients with colorectal cancer, efficacy prediction, the development of accurate individual treatment is a new research hotspot in this field. In this article, we summarize the research results of imaging techniques in the different stages of colorectal cancer diagnosis and treatment, such as preoperative staging, curative effect evaluation and prognosis evaluation.
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<pubDate>Sat,20 Mar 2021 00:00:00  GMT</pubDate>
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<title><![CDATA[Advances in risk factors and imaging prediction for pathological fractures of spinal metastases]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2021.03.029</link>
<description><![CDATA[Pathological fractures are a serious complication of spinal metastases. The increasing number of patients with cancer and their prolonged life expectancy have led to an increase in the number of patients with spinal metastases. If early identification of those at high risk for pathological fractures can be made, it can help to intervene earlier to improve the quality of patients' final life. This review has summarized advances in the risk factors and imaging prediction tools for pathological fractures in spinal metastases.]]></description>
<pubDate>Sat,20 Mar 2021 00:00:00  GMT</pubDate>
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<title><![CDATA[Clinical application progress of magnetic resonance simultaneous multi-slice technology]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2021.03.030</link>
<description><![CDATA[The simultaneous multi-slice (SMS) technique utilizes a multiband radiofrequency pulse to excite and acquire multiple slices simultaneously, which represents the beginning of a new era of multi-slice magnetic resonance imaging. At present, the rapid imaging technology has been commercialized and put into clinical use, the scope of research has also been extended from the nervous system to other parts and organs of the body. This article reviews a large number of literatures and reviews the progress of the research on the application of SMS technique.]]></description>
<pubDate>Sat,20 Mar 2021 00:00:00  GMT</pubDate>
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