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<title>Chinese Journal of Magnetic Resonance Imaging RSS feed</title>
<link>http://med-sci.cn/cgzcx/en/contents_list.asp?issue=201104</link>
<language>zh-cn</language>
<copyright>An RSS feed for Chinese Journal of Magnetic Resonance Imaging</copyright>
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<title><![CDATA[Strengthening MR imaging diagnosis and research on multiple sclerosis]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.3969/j.issn.1674-8034.2011.04.001</link>
<description><![CDATA[The clinical classification, clinical diagnostic criteria, magnetic resonance imaging (MRI) diagnostic criteria, and major differential diagnosis of multiple sclerosis (MS) were overviewed. The role of MRI in the diagnosis of MS was emphasized, and the importance of MRI in the relevant research on MS was also elucidated.]]></description>
<pubDate>Wed,20 Apr 2011 00:00:00  GMT</pubDate>
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<title><![CDATA[Application of MRI in multiple sclerosis: Interpretation of recommendations for using MRI in multiple sclerosis guideline issued by Spain Society of Neurology in 2010]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.3969/j.issn.1674-8034.2011.04.002</link>
<description><![CDATA[During the last two decades, since the most sensitive of magnetic resonance imaging (MRI) to multiple sclerosis (MS) lesions, MRI has been widely used in the diagnosis and treatment monitoring. But, the application of MRI in every day clinical practice is still suboptimal. For this reason, an expert group on MS of Spain Society of Neurology, based on an extensive review of the literature and on their own experience, produced a consensus on recommendations for using and interpreting MRI results in MS. It provides methods for different type and course of MS. These guidelines are intended to assist in the use of conventional MRI for the diagnosis and monitoring of patients with MS. In addition, they should provide a foundation for the development of non-conventional MRI techniques in clinical application and studies of MS. This article interprets the guideline, illustrates the contents, provides relevant knowledge and addresses some points with author’s sight, in order to assist in Chinese medical practice.]]></description>
<pubDate>Wed,20 Apr 2011 00:00:00  GMT</pubDate>
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<title><![CDATA[Advancement of functional MR imaging in multiple sclerosis]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.3969/j.issn.1674-8034.2011.04.003</link>
<description><![CDATA[One of the important clinical manifestations of multiple sclerosis (MS) is cognitive dysfunction. There is increasing evidence that the degree of cognitive dysfunction does not simply depend on the extent of tissue destruction, but rather represents a complex balance among tissue damage, tissue repair, and cortical reorganization in patients with MS. Functional magnetic resonance imaging (fMRI) and resting-state fMRI provides information regarding the extent and nature of neuroplasticity, which may contribute to the maintenance of normal performance despite scattered brain lesions. An altered recruitment of regions normally devoted to the performance of a given task and/or the recruitment of additional areas, which are not typically activated by healthy people for performing that given task, have been described in patients with MS, independent of their clinical phenotype when investigating the visual, cognitive, and motor systems. These functional changes have been related to the extent and severity of brain damage within and outside T2-visible lesions on conventional MR imaging and to the involvement of specific central nervous system (CNS) structures, including the spinal cord and the optic nerve. Brain functional changes have been shown to be dynamic over time, not only after an acute relapse, but also in clinically stable patients. This review will focus on the contribution of task functional MR imaging and resting-state functional MR imaging techniques in the evaluation of MS and provide an overview of functional MR imaging techniques with regard to current findings, clinical correlations, and future directions.]]></description>
<pubDate>Wed,20 Apr 2011 00:00:00  GMT</pubDate>
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<title><![CDATA[Review some MRI signs of multiple sclerosis and its clinical significance]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.3969/j.issn.1674-8034.2011.04.004</link>
<description><![CDATA[Objective: To investigate some MRI signs of the multiple sclerosis and review the literature, so as to elevate the rate of correct diagnosis. Materials and Methods: A total of 41 subjects with ﬁnal diagnosis of multiple sclerosis were selected between January 2009 and March 2011 as case group. The sex ratio was 18 males to 23 females. The age ranged from 11 to 52 years old, and the course of disease was from one month to five years. All the patients underwent MRI examination. Results: In addition to conventional imaging manifestations, the multiple sclerosis often presented ice-melting sign, plaster sign, tree sign, path sign, horn sign and converse comma sign. Conclusion: These signs of multiple sclerosis have important value for the correct diagnosis.]]></description>
<pubDate>Wed,20 Apr 2011 00:00:00  GMT</pubDate>
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<title><![CDATA[MRI findings of subcallosal <sup><sup>,</sup></sup>dot-dash<sup><sup>,</sup></sup> sign in patients with opticospinal multiple sclerosis]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.3969/j.issn.1674-8034.2011.04.005</link>
<description><![CDATA[Objective: To evaluate the dignostic value of the subcallosal dot-dash sign in patients with opticospinal multiple slcerosis (OSMS). Materials and Methods: The sagittal thin slice T2-FLAIR images were obtained in 42 OSMS patients and 27 normal controls by using GE 3.0 T MR system. The subcallosal dot-dash sign was observed on mid-sagittal planes. Results: The positive rate for subcallosal dot-dash sign was 66.67% (28/42) in OSMS patients. The younger OSMS group (<50 years) had a higher positive rate (73.5%) for subcallosal dot-dash sign than older OSMS group (≥50 years) (37.5%). The subcallosal dot-dash sign was not seen in the normal controls. Conclusion: The subcallosal dot-dash sign on sagittal plane may be a relative characteristic MR ﬁndings for OSMS.]]></description>
<pubDate>Wed,20 Apr 2011 00:00:00  GMT</pubDate>
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<title><![CDATA[Value of anti-aquaporin-4 antibody on Chinese patients with neuromyelitis optica]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.3969/j.issn.1674-8034.2011.04.006</link>
<description><![CDATA[Objective: To determine the value of AQP4 antibody in Chinese patients with NMO, HR-NMO (High risk NMO) and classic multiple sclerosis (MS), and also to investigate clinical features and progonosis of  patients with anti-AQP4 antibodies seropositive patients. Materials and Methods: Sera of patients with NMO, HR-NMO and MS were all investigated for the presence of AQP4 antibody by indirect immunofluorescence using human AQP4-transfected cells. The diagnositic and prognositic value of anti-AQP4 antibody were evaluated in 210 patients with NMO (n=53), HR-NMO (n=42) including optico-spinal MS (OSMS), longitudinally extensive transverse myelitis (LETM), recurrent ON (RON) and ON or TM with other antoimmune disease, classic MS (n=86), and other neurological diseases (n=29). Results: In our study, the anti-AQP4 antibody’s seropositivity in the NMO group was 71%, and the specificity was 91%. There were significant differences among NMO, HR-NMO and MS with respect to AQP4 antibody (P<0.05). Also, there were significant differences between the NMO/HR-NMO and MS group with respect to sex, accompanying with severe ON, TM, brain MRI normal, spinal-cord lesion having more than 3 segments, and anti-AQP4 antibody positive (P<0.05). And 36 (66.7%) of 55 seropositive patients were found to present with severe ON, 41 (75.9%) with TM, 30 (55.6%) with spinal-cord lesion >3 segments, 8 (14.8%) develop to ON relapse and 19 (35.2%) TM relapse within 24 median months follow-up. There were signiﬁcantly differences between seropositive and seronegative patiets with respect to accompanying with severe ON, TM, spinal-cord lesion >3 segments, developing to ON relapse and TM relapse (P<0.05). Conclusion: AQP4 antibody is a sensitive and speciﬁc biomarker for discrimination between NMO, MS and other neurological diseases.]]></description>
<pubDate>Wed,20 Apr 2011 00:00:00  GMT</pubDate>
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<title><![CDATA[Susceptibility-weighted imaging and dynamic susceptibility contrasted MR perfusion imaging of normal-appearing white matter around plaques in multiple sclerosis]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.3969/j.issn.1674-8034.2011.04.007</link>
<description><![CDATA[Objective: To determine the correlation between iron deposit and perfusion by quantificationally measuring the phase value and perfusion indices in normal-appearing white matter (NAWM) in multiple sclerosis (MS) patients. Materials and Methods: Thirty-one clinically proven MS cases were performed with susceptibility-weighted imaging (SWI) and dynamic susceptibility contrasted MR perfusion imaging (DSC-PI). Thirty age-matched healthy volunteers were participated in this study as a control. Features of MS plaques in ﬁltered phase images (FPI) were ﬁrst assessed. The measurements of phase values and perfusion parameters (including CBF and CBV) were taken and compared by using paired t test, and the correlations between phase values and perfusion parameters, as well as phase values and EDSS was respectively evaluated by using Pearson correlative analysis. Results: In 31 cases of MS, the round or oval hypointense foci with or without small veins were considered as the characteristic ﬁnding of MS plaques. In comparison with the controls, the phase values of NAWM surrounding MS plaques were signiﬁcantly lower in the MS group (P<0.05). Pearson correlation analysis revealed a significant correlation between the phase values of bilateral parietal NAWM and EDSS (P<0.05). As for the bilateral parietal and frontal NAWM, their phase values also significantly correlated with the rCBF (P<0.05). Conclusion: The phase values of NAWM in the MS patients varied with the cerebral perfusion, which also correlated with the EDSS, and could be used to evaluate the course changes of MS patients.]]></description>
<pubDate>Wed,20 Apr 2011 00:00:00  GMT</pubDate>
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<title><![CDATA[Prelimary study of lumbar intertebral disc degeneration with magnetic resonance spectroscopy, T2 relaxation times and apparent diffusion coefficient]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.3969/j.issn.1674-8034.2011.04.008</link>
<description><![CDATA[Objective: To explore the value of T2 relaxation time, magnetic resonance spectroscopy (MRS) and apparent diffusion coefficient (ADC) in the lumbar intervertebral disc degeneration. Materials and Methods: Comparison of ADC values, MRSRATIO and T2 relaxation times in 177 discs was performed at different anatomic levels and different Pfirrmann grades in 40 patients. Results: The T2 relaxation times and ADC values were signiﬁcantly correlated with Pﬁrrmann grades in different discs, but not in different anatomic levels. ADC values and T2 relaxation time were not correlated with different anatomic levels. Conclusion: ADC values and T2 relaxation time of the lumber intervertebral discs were correlated with increasing Pfirrmann grade. The results of this study support the feasibility of quantitatively assessing spinal degeneration. The values of the MRSRATIO in lumbar intervertebral disc degeneration will be further studied.]]></description>
<pubDate>Wed,20 Apr 2011 00:00:00  GMT</pubDate>
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<title><![CDATA[B value selection of diffusion-weighted MR imaging in differentiating malignant and benign liver lesions]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.3969/j.issn.1674-8034.2011.04.009</link>
<description><![CDATA[Objective: To evaluate the diagnostic value of diffusion-weighted imaging (DWI) in differentiating malignant and benign liver lesions by using different b values. Materials and Methods: Seventy-six consecutive patients with liver mass and eleven patients with liver cirrhosis were recruited and underwent CT and MR scans. DWI was performed on a 1.5 T MR scanner in all patients using three b values (300, 500, 700 s/mm2). Thirty normal patients were recruited as control group. Apparent diffusion coefﬁcient (ADC) values of the mass were calculated on the workstation and compared between malignant and benign lesions using two independent sample Wilcoxon rank sum test. Results: 25 cases were diagnosed as malignant tumors including 13 cases of hepatocellular carcinoma, 10 cases of metastasis, 2 cases of cholangiocellular carcinoma; Fifty-one patients were diagnosed as benign lesions including 23 cases of cavernous hemangioma, 18 cases of cyst, 7 cases of abscesses, 3 cases of focal nodular hyperplasia. The ADC values and the ratio of ADC of lesion/liver parenchyma of malignant lesions were signiﬁcantly lower than those of benign lesions (P<0.05). The sensitivity, specificity and accuracy were 71.4%, 80.6% and 76.9%, 95.0%, 78.1% and 73.1%, 90.0%, 77.5% and 77.5% respectively when b=300, 500 and 700 by using a threshold ADC of less than 1.60, 1.65, 1.41×10-3 mm2/s respectively. The sensitivity, speciﬁcity and accuracy were 60.0%, 81.8% and 73.6%, 65.0%, 86.1% and 78.6%, 75.0%, 94.9% and 88.1% respectively by using a threshold ADC ratio of lesion/liver less than 1.0. Liver abscesses had various ADC values ranging from 0.98 to 2.61×10-3 mm2/s. Conclusion: The ADC values and the ratios of ADC of lesion/liver parenchyma of malignant lesions were signiﬁcantly lower than those of benign lesions. The differentiating diagnostic value is more effective when b=500 is used. But the ADC values were overlapping between the malignant and benign liver lesions. Liver abscesses had various ADC values and should be diagnosed by combining with clinical and laboratory examinations.]]></description>
<pubDate>Wed,20 Apr 2011 00:00:00  GMT</pubDate>
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<title><![CDATA[Metabolic changes of liver cell apoptosis: an in vivo 1H magnetic resonance spectroscopy study]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.3969/j.issn.1674-8034.2011.04.010</link>
<description><![CDATA[Objective: To explore the feasibility of dectecting liver cell apoptosis in liver injury model by using magnetic resonance spectroscopy (MRS), and endeavor to find the characteristic changes of MRS. Materials and Methods: Twenty-seven New Zealand white rabbits were randomly divided into the control group (n=10) and the treated group (n=17). The rabbits in the treated group were intraperitoneally (i.p.) injected with sodium selenite while the ones in the control group with saline. At 48 hours after the injection, in vivo liver 1H-MRS were collected using point resolved spectroscopy sequence under the same conditions. After MR scanning, the rabbits were sacrificed immediately for histopathological examination. The 1H-MRS data were processed by SAGE 7.0 software to analyze the ratio of lipid/water (Lip/Water) and total choline/water (tCho/Water) in unsuppressed water spectral and the ratio of total choline/lipid (tCho/Lip) in suppressed water spectra. Statistical analysis was done by a two-tailed independent t test. Results: All of the listed tests were fully ﬁnished in 25 rabbits (15 treated and 10 controls). The MRS curves, mainly with peaks appearing at correct positions, could be analyzed. From MR spectra, there are some differences between the treated group and the control one. In unsuppressed water spectra, the ratio of Lip/Water (0.029±0.024, n=12) in treated group is higher than that in control group (0.014±0.007, n=10) (P<0.05); the ratio of tCho/Water (0.001±0.0005, n=12) in the treated group is signiﬁcantly lower than that (0.0030±0.0003) in control group (P<0.05). In suppressed water spectra, the ratio of tCho/Lip (0.093±0.007, n=12) in the treated group is also signiﬁcantly lower than that in control group (0.210±0.061, n=10) (P<0.05). The percentage of apoptotic cells was 9.2±3.1% in the model rats, and 0.27±0.07% in controls (P<0.001). Conclusion: After the injections, there are some characteristic differences between the 1H-MRS in the treatment group and that in the control group. In vivo 1.5 T 1H-MRS can be used to detect metabolic activity of this selenite-induced rabbit liver injury model, and liver cell apoptosis as well.]]></description>
<pubDate>Wed,20 Apr 2011 00:00:00  GMT</pubDate>
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<title><![CDATA[Proton magnetic resonance spectroscopy of the breast]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.3969/j.issn.1674-8034.2011.04.011</link>
<description><![CDATA[Contrast-enhanced MRI has gained acceptance as an important breast imaging modality. However it does not always provide a definitive pathology. Initial studies where in vivo proton MR spectroscopy has been added as an adjunct to dynamic contrast-enhanced MR imaging of the breast have shown promising results and a growing number of research groups are incorporating the technique into their breast MR protocols. The aim of this article is to illustrate the expected examination results and outline some of the pitfalls associated with undertaking a breast MRS examination.]]></description>
<pubDate>Wed,20 Apr 2011 00:00:00  GMT</pubDate>
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<title><![CDATA[Status of MR imaging diagnosis of diffuse axonal injury]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.3969/j.issn.1674-8034.2011.04.012</link>
<description><![CDATA[Diffuse axonal injury (DAI) is a serious form of brain injury, which is a primary cause of the death and disability of patients. The clinical manifestations of DAI lack specificity. Therefore the imaging diagnosis is attracting more and more attention. With the continuous development of MR technique, the MRI diagnostic level of DAI is also gradually improving. This article reviews the various MRI sequences for diagnosing DAI and predicts the future prospects of their application.]]></description>
<pubDate>Wed,20 Apr 2011 00:00:00  GMT</pubDate>
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<title><![CDATA[Wrist pain: application and research progress of MR imaging]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.3969/j.issn.1674-8034.2011.04.013</link>
<description><![CDATA[MRI examination can clearly reflect the contents of the wrist contour and position of triangular fibrocartilage complex (TFCC), articular cartilage, carpal interosseous ligament, synovial fluid, bone marrow changes and multi-level bone structural changes of joint area. In this literature, MR imaging examination in the wrist pain was reviewed, introducing commonly examination methods of the wrist, MR imaging findings of common diseases which result in wrist pain and a number of new imaging methodologies.]]></description>
<pubDate>Wed,20 Apr 2011 00:00:00  GMT</pubDate>
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<title><![CDATA[Analysis of the common MR signs in patients with multiple sclerosis]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.3969/j.issn.1674-8034.2011.04.014</link>
<description><![CDATA[This article introduced the clinical manifestations and the pathological changes in multiple sclerosis (MS). The typical MRI signs, including "fried egg sign", "open-ring sign", "arclike sign", and "halo sign" in acute/subacute stage, "subcallosal striation sign", "dot-dash sign" in early stage with callosal involvement, "Dawson's fingers" along the white matter venules, and typical findings in the spinal cord, were described and elucidated. These characteristic signs are important and helpful in the diagnosis and differential diagnosis of MS, and are valuable in the assessment of disease progression and evaluation of therapeutic effect.]]></description>
<pubDate>Wed,20 Apr 2011 00:00:00  GMT</pubDate>
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