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<title>Chinese Journal of Magnetic Resonance Imaging RSS feed</title>
<link>http://med-sci.cn/cgzcx/en/contents_list.asp?issue=201504</link>
<language>zh-cn</language>
<copyright>An RSS feed for Chinese Journal of Magnetic Resonance Imaging</copyright>
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<title><![CDATA[MRI features of rosette-forming glioneuronal tumor]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.3969/j.issn.1674-8034.2015.04.001</link>
<description><![CDATA[Objective: To study the radiographic features of rosette-forming glioneuronal tumor (RGNT), and enhance neuroradiologist’s awareness of this newly described tumor. Materials and Methods: The radiological images of 10 patients with pathologically proved RGNT were retrospectively analyzed. There were 3 males and 7 females, with the age between 8 to 45 years. Routine MR (10 cases) and CT (3 cases), contrast-enhanced MR (10 cases) were performed. Results: There were located in cerebellar vermis (4 cases), in the fourth ventricle (2 cases), in cerebellar hemisphere (1 case), in pons (1 case), in the cervical spinal cord (1 case), in thoracic and lumbar spinal cord (1 case).The solid component of the tumor showed slightly hypo-isointense on T1WI and slightly hyperintense on T2WI.The cystic component of the tumor appeared hypointense on T1WI and hyperintense on T2WI. The enhancement pattern was various, from mild to moderate heterogenous enhancement (6 cases), ring (1 case), or focal enhancement which is nodular (2 cases), spot-like (1 case). Eight cases showed mild peritumoural edema and 1 case showed moderate edema. Four cases accompanied with obstructive hydrocephalus and 1 case with syringomyelia. On plain CT scan, solid regions showed slightly low density, cystic regions appeared low density and 2 cases showed intratumoral bleeding. Conclusion: RGNT might occur in younger age and has mild female predilection. Imaging appearance of RGNT has certain characteristics and should be considered for differentiation.]]></description>
<pubDate>Mon,20 Apr 2015 00:00:00  GMT</pubDate>
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<title><![CDATA[SWI study on astrocytoma grading and differential diagnosis of astrocytoma and solitary metastases]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.3969/j.issn.1674-8034.2015.04.002</link>
<description><![CDATA[Objective: The purpose of this study is to explore the value of the intratumoral susceptibility signal intensity (ITSS) in grading of astrocytoma and in differential diagnosis of astrocytomas and metastases. Materials and Methods: Forty-two recruited patients with brain tumors confirmed pathologically, including 14 solitary metastases and 28 astrocytomas(WHO grade Ⅰ=3, grade Ⅱ=8, grade Ⅲ=9 and grade Ⅳ=8) underwent conventional MRI examinations and susceptibility weighted imaging (SWI). Intratumoral susceptibility signal intensity(ITSS)in tumor parenchyma was obtained. The ITSS values were further compared between different grades of astrocytoma and between astrocytomas and metastases by Wilcoxon test. Receiver operating characteristic curve (ROC) was used to determine the differentiation ability of ITSS number for astrocytoma grading and brain tumors differential diagnosis. Spearman coefficient correlation analysis was used to analyze the relation between ITSS and astrocytoma grade. Results: The mean values of ITSS in grade Ⅰ, Ⅱ, Ⅲ, Ⅳ astrocytomas and metastases were respectively (3.0±2.67), (4.12±0.64), (18.11±2.15), (18.75±2.48) and (6.14±1.56). Significant difference was observed in high-grade (Ⅲ and Ⅳ) and low-grade (Ⅰ and Ⅱ) astrocytomas (H=13.156, P＜0.01), and even between the gradesⅡ and Ⅲ astrocytomas (H=7.835, P＜0.01), while no significant difference was found between grade Ⅲ and Ⅳ astrocytomas(H=0.021, P=0.885). Positive correlation was observed between ITSS and astrocytoma grade (r=0.746，P=0.000). Area under the ROC curve (AUC) was 0.912 in differentiation of the high-grade and low-grade astrocytomas when the cutoff value was set as 7.5, and the sensitivity and specificity were 88.2% and 81.8%. AUC was 0.903 in differentiation of the grade Ⅱ and grade Ⅲ astrocytomas when the cutoff value was set as 6.0, and the sensitivity and specificity were 100% and 87.5%. Significant differences of ITSS were observed between the metastases (mean rank=9.89) and high-grade astrocytomas(mean rank=21.06) (H=11.679, P=0.001), while no significant difference was observed between the metastases and low-grade astrocytomas. AUC in differentiation of the high-grade astrocytomas and metastases was 0.861 when the cutoff value of ITSS was set as 6.5, and the sensitivity and specificity were 94.1% and 71.4%. Conclusion: ITSS is helpful to determine the grade of astrocytoma and differentiate the high grade astrocytoma and metastates, which reflects the microhemorrhage and tumor vessels in the tumor parenchyma.]]></description>
<pubDate>Mon,20 Apr 2015 00:00:00  GMT</pubDate>
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<title><![CDATA[Diffusion tensor imaging study of normal neonatal brain maturation]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.3969/j.issn.1674-8034.2015.04.003</link>
<description><![CDATA[Objective: The purpose of this study was to investigate the developing status and characteristics of cerebral white matter during the neonatal period by using diffusion tensor imaging technique. Materials and Methods: In this study, 38 newborns were selected, including eighteen preterm infants (appropriate for gestational age) and twenty term infants (normal birth weight), they were divided into three groups according to their gestational age, fractional anisotropy obtained from each region of interest was analyzed. Results: The differences of FA values between left and right hemispheric white matter regions were no significant statistically. FA values for the peripheral white matter regions were lower than the values for deep white matter structures,in the deep white matter, the splenium of corpus callosum showed larger FA than genu, and the anterior limb of internal capsule showed smaller FA than posterior limb of internal capsule, the FA values for the splenium were higher than the values for the posterior limb of internal capsule. Among peripheral white matter, FA in central white matter (the level of central semiovale) were the highest, no significant differences were observed between anterior and posterior white matter (the level of central semiovale) (all P＞0.05). FA values for all measured regions in group Ⅲ were more than that values in groupⅠ, and the differences were significant statistically (all P＜0.05), comparison between adjacent groups, there were significant statistically only in part of regions of interest. Conclusion: Diffusion tensor imaging technique is very usefull in the study of neonatal white matter maturation, FA value can assess myelin development quantitatively.]]></description>
<pubDate>Mon,20 Apr 2015 00:00:00  GMT</pubDate>
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<title><![CDATA[Misdiagnosis of atypical meningioma MRI manifestation analysis]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.3969/j.issn.1674-8034.2015.04.004</link>
<description><![CDATA[Objective: To study the relationship between the atypical meningioma of MRI findings and its pathological features, analyze the reasons of misdiagnosis, to improve the diagnostic level. Materials and Methods: MRI findings of 22 cases meningioma confirmed by surgery and pathology were analyzed retrospectively. All cases were performed enhanced MRI. Results: MRI findings of all the 22 cases meningioma were as following: 8 cases were exactly like intracerebral tumors, 8 cases located at uncommon sites, and 6 cases located at conman sites.  Fifteen cases showed heterogeneous signal on MRI, 12 cases had invasive boundary. Pathological grade: WHO Ⅰ grade 12 cases, WHO Ⅱ grade 4 cases, WHO Ⅲ  grade 6 cases. Conclusions: The reasons for misdiagnosis of meningioma on MRI include complexity of pathological changes, biological characteristics and unexpected locations. A key point of prompting the diagnosis of meningioma is to recognize the atypical findings on MRI combined with the pathological features.]]></description>
<pubDate>Mon,20 Apr 2015 00:00:00  GMT</pubDate>
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<title><![CDATA[The correlation analysis between the cerebral microbleeds and hypertension]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.3969/j.issn.1674-8034.2015.04.005</link>
<description><![CDATA[Objective: To evaluate the correlation between the cerebral microbleeds and the blood pressure. Materials and Methods: A total of 524 subjects were carried out conventional sequences of T1 weight imaging (T1WI), T2 weight imaging (T2WI), FLAIR, DWI and susceptibility weighted imaging (SWI). The brain regions, number and grades of the CMBs were analyzed. The hypertension history, blood pressure values before MR examination were recorded. The blood pressure  level of the subjects were divided into different grades. The subjects were divided into two groups: CMBs group and non CMBs group. Then we compare the differences of gender, age, hypertension period (year), the prevalence rate of hypertension, high blood pressure level, the average systolic pressure, diastolic pressure and CMBs sites between the two groups.The correlation between CMBs and the age, blood pressure grade, Systolic Bp and Diastolic BP was analyzed. Results: The hypertension prevalence, the average systolic blood pressure and the diastolic blood pressure of CMBs group were higher than those of values in non CMBs group. There is a longer hypertension period in CMBs group compared with non CMBs group. The CMBs distribution of different areas had significant difference. The grades of CMBs were correlated with the age, blood pressure grade, Systolic Bp and Diastolic BP. Conclusions: There was significant correlation between the CMBs and hypertension.]]></description>
<pubDate>Mon,20 Apr 2015 00:00:00  GMT</pubDate>
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<title><![CDATA[Clinical application of DTI in mild traumatic brain injury and its significance]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.3969/j.issn.1674-8034.2015.04.006</link>
<description><![CDATA[Objective: The purpose of this study was to detect intracranial axonal damage after mild traumatic brain injury using diffusion tensor imaging (DTI), and assess the application of DTI in mild traumatic brain injury clinically. Materials and Methods: Thirty patients were prospectively enrolled from Tianjin First Center Hospital, who sustained a mild TBI, 30 normal volunteers were also recruited as control. All the participants underwent routine MRI, DTI scanning, and Rivermead Post Concussion Symptoms Questionnaire (RPQ) within the day of examination. Results: The RPQ scores of mTBI patients were higher than control (P＜0.01). Whole brain analysis of DTI revealed the areas with higher FA values: right cerebellum, occipital lobe, declive, lingual gyrus, the triangular part of right inferior frontal gyrus, Precuneus. The areas with lower FA values were the optic radiation, cerebral peduncle, corpus callosum, the white matter under middle frontal gyrus, the white matter under precentral gyrus. Conclusion: We had shown that DTI can identify abnormalities in patients following mTBI. DTI were sensitive in finding intracranial latent lesion by mTBI. We believed such early identification could certainly be used to help diagnosis, and might play a key role in prognosis of mTBI.]]></description>
<pubDate>Mon,20 Apr 2015 00:00:00  GMT</pubDate>
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<title><![CDATA[Evaluation of 3D-TOF and 3D-FIESTA combined with MPR in microvascular decompression for trigeminal neuralgia by 3.0 T MRI system]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.3969/j.issn.1674-8034.2015.04.007</link>
<description><![CDATA[Objective: To investigate the value of 3D-TOF and 3D-FIESTA for preoperative assessment in microvascular decompression for trigeminal neuralgia. Materials and Methods: 187 cases of primary trigeminal neuralgia underwent microvascular decompression (MVD) of Xiangya Hospital were retrospectively analyzed, the 3D-TOF and 3D-FIESTA findings preoperative and the intraoperative exploration results were compared. Results: 3D-TOF and 3D-FIESTA identified surgically verified neuro-vascular compression in 173 of 187 (92.3%) symptomatic nerves. Neurovascular compression was observed in 29 of 187 (16%) of asymptomatic nerves, 179 cases (95.6%) which neurovascular compression (NVC) were observed during operation underwent MVD：73 cases (40.8%) with SCA, 28 cases (15.4%) with AICA, 5 cases (3.2%) with PICA, 17 caces with BA (9.8%), 35 cases (20.2%) with compounding compression, 11 cases (6.2%) with vein. 3D-TOF and 3D-FIESTA were not identified in 14 cases (7.7%), of which NVC 10 cases (58.8%) weren't observed during operation underwent trigeminal rhizotomy. Before operations, the 187 cases findings of 3D-TOF combined with 3D FIESTA sequence demonstrated that 173 in 187 (92.3%) were neuro-vascular compression which were ipsolateral with the symoptoms. The procedures of microvascular decompression revealed that 179 in 187 (95.6%) were neuro-vascular compression, including that 73 (40.8%) cases with SCA, 35 (20.2%) cases with combined compression, 28 (15.4%) cases with AICA, 17 (9.8%) cases with BA, 11 (6.2%) cases with vein, 5 (3.2%) cases with PICA. Conclusions: 3D-TOF and 3D-FIESTA combined with 3-D MPR which can clearly display spatial relationship of trigeminal nerve and around vessels is an effective method for preoperative assessment in microvascular decompression for trigeminal neuralgia.]]></description>
<pubDate>Mon,20 Apr 2015 00:00:00  GMT</pubDate>
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<title><![CDATA[The diagnostic value of triple-negative breast cancer using 3.0 T MRI]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.3969/j.issn.1674-8034.2015.04.008</link>
<description><![CDATA[Objective:  To invstigate the specific findings of triple-negative breast cancer (TNBC) with dynamic contrast-enhanced MRI and DWI, and to provide the  reference for presurgical evaluation. Materials and Methods: Two hundred and fifty-one patients with breast cancer who underwent operation from Augest, 2012 to June, 2014 were included. Seventy patients were TNBC, while 181 patients were ER(+)/PR(+)/HER-2(-) cancer. Comparing the dynamic contrast-enhanced breast MRI and DWI imaging findings of these two subtypes and making the appropriate statistical analysis. Results: Compared to ER(+)/PR(+)/HER-2(-) tumors, TNBC cancers were presented with single (P=0.018), larger tumor size (P=0.002), higher histologic grade (P＜0.001). MRI features associated with TNBC tumors included mass enhancement (P=0.026), lobulated (P＜0.001), smooth margins (P=0.005), ring-enhancement  (P＜0.001) and areas of intratumoral high T2 signal intensity (P＜0.001). Moreover, the TNBC appeared higher ADC value (P=0.031). Conclusions: Preoperative MRI is helpful in differentiating TNBC and contrast enhanced ER (+) /PR (+) /HER-2 (-) cancer. It would  be one of the most important noninvasive examination methods to preoperatively evaluate the breast cancer, and provide imaging basis for clinical treatment.]]></description>
<pubDate>Mon,20 Apr 2015 00:00:00  GMT</pubDate>
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<title><![CDATA[The correlation between DCE-MRI parameters and pathological characteristics in rectal cancer]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.3969/j.issn.1674-8034.2015.04.009</link>
<description><![CDATA[Objective: To evaluate the relationship between the the characteristics of dynamic contrast-enhanced MRI ( DCE-MRI) parameters and the degree of pathologic differentiation as well as Dukes staging in rectal cancer. Materials and Methods: A retrospective investigation of DCE-MRI image of fifty six patients with rectal cancer confirmed by surgical pathology was made, the time intensity curve (TIC) was rendered, the Ktrans, Ve, Kep parameters graphs were constructed,  the characteristics of the TIC, Ktrans, Ve, Kep values as well as the correlation between the degree of tumor differentiation and Dukes stage were analyzed. Results: The TIC of rectal cancer and normal rectal wall around the tumor were divided into three types, in which 8 cases belonged to the type two, 48 cases belonged to the type three. The normal rectal wall around the tumor 41 cases belonged to the type one, 15 cases belonged to the type two. The Ktrans value increase with the worsening of the degree of differentiation and the increase of Dukes staging (P＜0.01).There was no statistically significant difference of Ve and Kep values. Conclusions: DCE-MRI can reflect the haemodynamics of internal tumors, TIC and Ktrans value have certain correlation with the degree of pathologic differentiation and Dukes staging. TIC and Ktrans may be used to evaluate the malignancy degree of rectal cancer.]]></description>
<pubDate>Mon,20 Apr 2015 00:00:00  GMT</pubDate>
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<title><![CDATA[Evaluation of T2WI and readout-segmented echo-planar imaging in diagnosing early prostate cancers: a study based on PI-RADS system]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.3969/j.issn.1674-8034.2015.04.010</link>
<description><![CDATA[Objectives: To compare the clinical utility of readout-segmented echo-planar imaging (RS-EPI) with single-shot echo-planar imaging (SS-EPI) in diagnosing early prostatic cancers. Materials and Methods: Twenty surgically-proved early prostate cancer patients were collected in this retrospective study. T2WI, RS-EPI and SS-EPI were evaluated by two blinded radiologists. By using 6 sub-region classification method the possibility of the presence of cancer at each sub-region was scored according to the PI-RADS system. The receiver operating characteristic (ROC) curve was used to analyze the diagnostic efficacy of the following 6 protocols: T2WI alone (protocol 1), SS-EPI alone (protocol 2), RS-EPI (protocol 3), a combination of T2WI and SS-EPI (protocol 4) and a combination of T2WI and RS-EPI (protocol 5). Results: The area under the ROC curve (Az) of protocol 1 to protocol 5 for region-based analysis were 0.789, 0.790, 0.874, 0.838, 0.881, respectively. ROC analysis revealed significant differences between protocol 1 and 3, 4, 5, and between protocol 2 and 3, 4, and between protocol 4 and 5 (P＜0.05). While the difference between protocol 1 and 2, between 3 and 4, 5 has no statistical significance (P＞0.05). Conclusions: The combination of T2WI and DWI can improve the diagnosis ability of early prostate cancers. Combination of T2WI and RS-EPI is a more effective approach than combination of T2WI and SS-EPI for the detection of early prostate cancers.]]></description>
<pubDate>Mon,20 Apr 2015 00:00:00  GMT</pubDate>
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<title><![CDATA[Research of magnetic resonance perfusion weighted imaging in the characteristics of cervical cancer]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.3969/j.issn.1674-8034.2015.04.011</link>
<description><![CDATA[Objective:  To explore the perfusion differences among cervical cancer, normal cervixand cervical intermural leiomyomas with magnetic resonance. Materials and Methods: We collected 32 cases of cervical cancer patients, 30 cases of normal cervix and 30 cases of patients with cervical intermural leiomyomas.Time signal-intensity curve (TIC), maximum enhancement (ME), steepest slope (SSmax), Time To Peak (TTP), were measured and analyzed on perfusion weighted imaging. Besides, the correlation between  characteristics of perfusion and hemodynamic  enhancement was calculated. Results: In the TIC type of cervical cancer group, "rapidly wash in followed by a plateau" had 25 cases, "rapidly wash in  followed by a slowly wash out" had  7 cases; in the TIC type of normal cervix group, "slow  wash in " had 22 cases, "rapidly  wash in  followed by a plateau" had  8 cases; in the TIC type of cervica intermural leiomyomas group, "rapidly  wash infollowed by a plateau" had  24 cases, "slowly wash in " had  6 cases. there are great statistically significant differences between ME, SSmax, TTP of the cervical cancer group and the normal cervix group (P＜0.001); there are also great statistically significant differences between cervical cancer group and cervical intermural leiomyomas group (P＜0.001). Conclusions: PWI could reflect the hemodynamic characteristics of cervical cancer well，which could help with the differential diagnosis of cervical cancer，and provide the reference  for the clinical evaluation.]]></description>
<pubDate>Mon,20 Apr 2015 00:00:00  GMT</pubDate>
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<title><![CDATA[The change of association between nephrogenic systemic fibrosis and gadolinium-based contrast agents: an updated meta-analysis applying Hill’s criteria]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.3969/j.issn.1674-8034.2015.04.012</link>
<description><![CDATA[Objective: To examine whether a causal link exists between gadolinium-based contrast agents (GBCAs) and nephrogenic systemic fibrosis (NSF) and if the link changes over time. Materials and Methods: Studies for analysis were identified by searching the PubMed, the Wiley Online Library, and the Cochrane Central Register of Controlled Trials up to December 18, 2014. Pooled odds ratios (OR) with 95% confidence intervals (CI) was calculated by using the fixed-effects model. Statistical heterogeneity was assessed by Cochrane’s Q test and I2 statistics. Publication bias was evaluated using peters test, funnel plots and fail-safe N. Quality assessment of included studies using Newcastle-Ottawa Scale (NOS). Influence analysis and cumulative meta  –analysis were also conducted in this study. All statistical analyses were performed by R software (R Core Team. R: A language and environment for statistical computing. R Foundation for Statistical Computing, Vienna, Austria. URL http://www.R-project. org, 2014). Hill’s criteria was used to evaluate evidence in support of a potential causal link between GBCAs and NSF. Results: A total of 14 studies including 6398 patients met the inclusion criteria, but 3 was excluded since they reported no NSF events. Meta-analysis of controlled trials indicated the GBCAs exposure may significantly increase the risk of NSF (OR=16. 50, 95%CI: 7.46-36.53, P＜0.01) and gadodiamide exposure may also increase the risk of NSF (OR=20.04, 95%CI: 3.72-107.78, P＜0.01). No heterogeneity (P=0. 819, I2=0%; P=0. 873, I2=0%, respectively) was observed across studies. Hill’s criteria suggested a potential causal link between GBCAs and NSF. In addition, the cumulative analysis demonstrated that the pooled ORs for GBCAs and NSF decreased post-2007 compared to pre-2007 (OR=26.71; 95%CI: 10.27-69.44). Conclusions: Although this meta-analysis suggests a strong association and potentially causal relation between GBCAs exposure and the incidence of NSF in patients with renal insufficiency, the relation decreased after 2007. More studies are warranted to examine the potential association between GBCAs other than gadodiamide and NSF.]]></description>
<pubDate>Mon,20 Apr 2015 00:00:00  GMT</pubDate>
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<title><![CDATA[Experimental research of superparamagnetic iron oxide for early magnetic resonance imaging diagnosis of hepatocarcinoma]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.3969/j.issn.1674-8034.2015.04.014</link>
<description><![CDATA[Early detection and diagnosis of liver cancer is an important issue that must be addressed. The development of molecular imaging provides a new way for early detection and diagnosis of hepatocellular carcinoma. Superparamagnetic iron oxide(SPIO) has a broad application prospect in biomedical field, and becomes a hot spot in the field of molecular imaging research currently. Compared to traditional magnetic resonance imaging(MRI) contrast medium(gadolinium), SPIO has many advantages, and can lead to negative enhancement for MRI. SPIO has wide applications in the biomedical field and can be used as not only as a drug-release carrier but also as a targeted probe carrier. SPIO has recently gained much attention in the field of molecular imaging research. SPIO is a specific MRI contrast agent for liver imaging and plays an important role in the diagnosis of hepatocellular carcinoma.]]></description>
<pubDate>Mon,20 Apr 2015 00:00:00  GMT</pubDate>
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