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<title>Chinese Journal of Magnetic Resonance Imaging RSS feed</title>
<link>http://med-sci.cn/cgzcx/en/contents_list.asp?issue=201604</link>
<language>zh-cn</language>
<copyright>An RSS feed for Chinese Journal of Magnetic Resonance Imaging</copyright>
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<title><![CDATA[Principle and application progress of chemical exchange saturation transfer (CEST) technique]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2016.04.001</link>
<description><![CDATA[Hydrogen protons, a component of many biological macromolecules like protein, glycosaminoglycan and glycogen, could be saturated by pre-saturated radio frequency pulses and exchanged with those hydrogen protons in the water, and then the measurement of these water molecule signals could reflect their content in the human body. This mechanism is the principal of a technique called Chemical Exchange Saturation Transfer (CEST). Meanwhile, as there is a close relation between these molecules and the incidence of tumor and stroke, this technique could be used in the diagnosis and treatment. With regard to its noninvasive and nonradiative nature, CEST has become a research hotspot. Therefore, the purpose of this article was to review the principle and application progress of this technique.]]></description>
<pubDate>Wed,20 Apr 2016 00:00:00  GMT</pubDate>
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<title><![CDATA[Research of chemical exchange saturation transfer in brain]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2016.04.002</link>
<description><![CDATA[Chemical exchange saturation transfer (CEST) imaging is a new method for magnetic resonance imaging theory of exchange in the magnetization transfer and chemical, the expansion of the new field of molecular magnetic resonance imaging, but it’s still in the research stage. The intracellular substances as an endogenous contrast agent, through the indirect detection of metabolite water signal information for tissue pH imaging and imaging of various metabolites. This paper mainly discusses the chemical and water exchange in the field of MRI saturation transfer phenomenon, expounds the principle, research status and the application in brain diseases used the different field strength clinical MRI scanner.]]></description>
<pubDate>Wed,20 Apr 2016 00:00:00  GMT</pubDate>
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<title><![CDATA[Magnetic resonance amide proton transfer (APT) imaging:description of technical principles and potential applications]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2016.04.003</link>
<description><![CDATA[Amide proton transfer (APT) imaging is related to chemical exchange saturation transfer (CEST) technique. This review focuses on description of APT technical principles, factors influencing APT imaging, and relationship between in vivo APT imaging and nuclear Overhauser effect (NOE). Potential clinical applications of APT technique, such as pH imaging, temperature imaging, as well as APT-weighted imaging for organs and tissues, are discussed.]]></description>
<pubDate>Wed,20 Apr 2016 00:00:00  GMT</pubDate>
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<title><![CDATA[Clinical applications of amide proton transfer magnetic resonance imaging]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2016.04.004</link>
<description><![CDATA[Amide proton transfer (APT) imaging is a noninvasive molecular magnetic resonance imaging (MRI) method based on chemical exchange dependent saturation transfer technique that detects endogenous mobile proteins and peptides, and amide proton exchange rates in biological tissues. APT weighted image is calculated by the magnetization transfer asymmetry between ±3.5 ppm which respect to the water frequency on z-spectrum. In recent years, APT MRI has been increasingly used for the diagnosis of diseases. In this article, we reviewed the developments of APT MRI in the clinical applications and scientific researches.]]></description>
<pubDate>Wed,20 Apr 2016 00:00:00  GMT</pubDate>
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<title><![CDATA[The value of “swallow tail” appearance of nigrosome on ESWAN at 3.0 T MR in the diagnosis of Parkinson’s disease]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2016.04.005</link>
<description><![CDATA[Objective: To explore the value of Enhanced gradient echo T2 star weighted angiography (ESWAN) findings of nigrosome at 3.0 T MR imaging in the diagnosis of Parkinson’s Disease (PD). Materials and Methods: The ESWAN findings of 58 patients with PD and 364 age-matched healthy control were retrospectively analyzed. All the subjects were divided into PD and non-PD group according to the presence or absence of nigrosome 1 on ESWAN imaging, e.g. “swallow tail” appearance, and the accuracy was evaluated. Results: Fifty-five (94.83%) of 58 PD patients did not show “swallow tail” appearance and the rest 3 were doubtful, while 344 (94.51%) of 364 non-PD patients did have this appearance. The sensitivity of “swallow tail” appearance in differentiating PD from non-PD patients was 95% and the specifity was 91%. Conclusion: The absence of “swallow tail” appearance in nigrosome on ESWAN imaging at 3.0 T MRI provides a new, easy and reliable tool for the diagnosis of PD.]]></description>
<pubDate>Wed,20 Apr 2016 00:00:00  GMT</pubDate>
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<title><![CDATA[The functional connectivity of hypothalamus in T2DM patients: a resting-state fMRI study]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2016.04.006</link>
<description><![CDATA[Objective: To investigate whether functional connection between hypothalamus and other brain regions is impaired in type 2 diabetes mellitus (T2DM), the resting-state MRI was utilized to analyze the connectivity between hypothalamus and other brain regions. Materials and Methods: This study included the T2DM patients who were diagnosed within 1-5years (T2DM, n=59), and age, sex, education-matched healthy control subjects(HC, n=49). T2WI, FLAIR, 3D-T1WI and resting-state fMRI data were collected by Siemens MR scanner. Functional connection values between bilateral hypothalamus and other voxels in the brain were calculated, the resulted values of both groups were compared using two-sample t-test to locate the regions with significant change. Then correlation analysis was conducted between clinical data and functional connection values extracted from significantly different brain regions. Results: Compared to healthy control subjects, T2DM patients showed significantly decreased functional connection values between left hypothalamus, right hypothalamus and right brainstem, left dorsolateral prefrontal cortex, orbitofrontal cortex, left Inferior parietal lobule, right middle occipital gyrus. In T2DM patients, functional connection values between left hypothalamus and inferior temporal gyrus,left precuneus, left fusiform also decreased significantly, however, the functional connection values in left insula increased; the functional connection values between right hypothalamus and left lingual gyrus, right precentral gyrus/postcentral gyrus decreased. Moreover, negative correlations were found between HbA1c and functional connection values between left hypothalamus and left dorsol ateral prefrontal cortex (r=–0.24, P=0.04) in T2DM patients group. Conclusion: The functional connection between hypothalamus and other brain regions is impaired in T2DM patients. Moreover, this study indicated that the change of functional connection values between left dorsolateral prefrontal cortex and left hypothalamus was significantly associated with diabetes mellitus severity. Resting-state MRI can reflect the severity of T2DM.]]></description>
<pubDate>Wed,20 Apr 2016 00:00:00  GMT</pubDate>
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<title><![CDATA[The discrimination between brain metastases from lung cancer and high-grade glioma with proton MR spectroscopy and its value for survival predictorsand]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2016.04.007</link>
<description><![CDATA[Objective: To investigate the clinical discrimination value of proton MR spectroscopy(1H-MRS) between brain metastasis from lung cancer and high-grade glioma, and access its prognostic value at the same time. Materials and Methods: Thirty-six patients of high-grade gliomas and forty-three patients of brain metastasis from lung cancer were studied. Thirty-six patients of high-grade gliomas and forty-three patients of brain metastasis from lung cancer were received 1H-MRS. The variety of metabolite peaks including n-acetylaspartate (NAA), choline (Cho) and creatine (Cr) were detected in different areas including tumor, peritumoral areas and the normal brain, at the same time the ratio of NAA/Cho, NAA/Cr and Cho/Cr were computed. Cox regression were performed for univariate and multivariate analyses to explore independent predictors influencing the survival of patients with lung cancer and brain metastases respectively. Results: Significant differences between peritumoral area of high-grade gliomas and brain metastasis from lung cancer were found in the ratios of Cho/Cr and Cho/NAA (P＜0.05). The ratios of NAA/Cr, Cho/Cr and NAA/Cho were independent survival predictors in patients with lung cancer and brain metastasis as indicated by Cox proportional hazard model(P＜0.05). Conclusion: The ratios of Cho/Cr and Cho/NAA in peritumoral area can be found in brain metastases from lung cancer with 1H-MRS, which is helpful in discrimination between lung cancer and high-grade gliomas. The ratios of Cho/Cr may be an independent survival predictors in patients with lung cancer and brain metastasis.]]></description>
<pubDate>Wed,20 Apr 2016 00:00:00  GMT</pubDate>
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<title><![CDATA[A primary fMRI study of the chinese language function: a free fluency paradigm]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2016.04.008</link>
<description><![CDATA[Objective: To design a stimulus task for Chinese free fluency, and explore the brains language function areas in Chinese people. Materials and Methods: Nineteen healthy Chinese volunteers underwent a BOLD-fMRI scan with a free fluency stimulus task, that was block design. All images were collected and processed by SPM 8, followed by a First- and Second-level analysis. The distribution, sizes(number of voxels), and peak intensity of activations were shown by Xjview. Results: All participants completed the language task in connection with chinese language functional areas located primarily in the right superior temporal gyrus. In this study, the left fusiform gyrus and left parahippocampal gyrus were not activated, and bilateral hippocampus with low-grade activations. Conclusion: This stimulus task effectively activated brain language areas relating to chinese free fluency. BOLD-fMRI located activated areas accurately, and quantified the size and peak intensity of activations. It was stable and reliable with good compliance from patients. This study shows that chinese free fluency.]]></description>
<pubDate>Wed,20 Apr 2016 00:00:00  GMT</pubDate>
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<title><![CDATA[The features and diagnostic value of MRI for infant brachial plexus injury]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2016.04.009</link>
<description><![CDATA[Objective: To explore the MRI manifestations and its diagnostic value for infant brachial plexus injury. Materials and Methods: MRI manifestations and EMG of 15 infants clinical-related materials confirmed to have brachial plexus injury from November 2011 to November 2014 were retrospectively analyzed. Kappa was used to analyze the difference. Results: Seven of fifteen infants had unilateral preganglionic or/and postganglionic brachial plexus injury. Preganglionic brachial plexus injury occurred in 28 nerves and postganglionic injury occurred in 51 nerves, and 12 cases had combined injury. The manifestations of preganglionic brachial plexus injury in MRI included nerve root disappearance or enlargement, nerve root sleeve form abnormality, and meningeal cyst. Postganglionic injury MRI findings showed nerve trunk enlargement, continuity interrupt line with CSF leak, adjacent structure disorder and edema and nerve trunk sheath enlarge. There was no significant difference between MRN and EMG on extent confirm(κ=0.718, P＜0.05). Conclusion: MRI is good at revealing brachial plexus injury in early time, and could be rational to the first and review examination.]]></description>
<pubDate>Wed,20 Apr 2016 00:00:00  GMT</pubDate>
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<title><![CDATA[The system applying and analyzing of Z spectrum in chemical exchange saturation transfer]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2016.04.010</link>
<description><![CDATA[Objective: To create a simple and friendly software toolkit to display and analyze Z spectrum of Chemical Exchange Saturation Transfer (CEST), which is convenient for clinicians and researchers to apply and research. Materials and Methods: The data is collected by conventional CEST imaging method, and the system is made by MATLAB GUI. Fitting the Z spectrum of different region of interest (ROI) which are selected by taking the mouse, and also carrying on its analysis and comparison. Results: The different positions and different pixel values of image’s ROI, the Z spectrum are different, which reflect different biological information. Conclusion: Z spectrum directly determines the final CEST signal analysis and relates biomedical information extraction. The functions of this system mainly include CEST image denoising, the formation of asymmetric magnetization transfer rate (MTRasym) mapping, selecting ROI and fitting the Z spectrum. To fit the Z spectra of ROI which are selected by taking the mouse.]]></description>
<pubDate>Wed,20 Apr 2016 00:00:00  GMT</pubDate>
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<title><![CDATA[Differential diagnosis of AIDS: study of multi b-value DWI double-exponential model]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2016.04.011</link>
<description><![CDATA[Objective: To discuss how mono-exponential model and double-exponential model of multi-b value diffusion weighted imaging perform in HIV diagnosis. Materials and Methods: Multi-b value DWI(b=0, 50, 150, 200400, 600, 800) was performed to 23 teenagers, 15 of whom were HIV-positive and 8 of whom were HIV-negative. By fitting the images of mono-exponential model and double-exponential model, ADCs, ADCf, ADC values in frontal lobe were compared between HIV-positive subjects and HIV-negative subjects by statistical analysis. Results: For left frontal lobe, HIV-positive subjects have significantly lower ADCf values than HIV-negative subjects. While ADCs, ADC values are not significantly different. Conclusion: Double-exponential model of multi-b value diffusion weighted imaging, especially ADCf values can be a reference in AIDS diagnosis.]]></description>
<pubDate>Wed,20 Apr 2016 00:00:00  GMT</pubDate>
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<title><![CDATA[MRI tracking study of SPIO labeled bone marrow stromal cells transplantation for treatment of lacunar stroke]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2016.04.012</link>
<description><![CDATA[Objective: To explore the feasibility of MRI technology in tracing bone marrow mesenchymal stem cells labeled with SPIO, and observe migration and therapeutic condition of BMSCs in focal cerebral infarction model. Materials and Methods: Investigate label efficiency and proliferation activity of three different concentrations of SPIO (25 μg/ml, 50 μg/ml, 75 μg/ml ) by Prussian blue staining and CCK8 method. A total of 28 male SD rats were randomly divided into normal control group (CON, n=4), sham operation group(SHAM, n=4), focal cerebral infarction group treated with SPIO only (MCAO+SPIO, n=10), and focal cerebral infarction treated with optmal SPIO-BMSCs (MCAO+SPIO-BMSC, n=10), MRI scan was underwent on 1 day, 9 days, 20 days, 30 days, 43 days after cell transplantation. Distribution of cell migration were observed by Prussian blue staining. Results: When label concentration was 50 μg/ml, Prussian blue staining efficiency was 100%. Compared with control group and 75 μg/ml group, 50 μg/ml group was significantly different (P<0.05). In MCAO+SPIO and MCAO+SPIO-BMSC groups, transplanted cells on T2WI and SWI sequences obviously show signal reducing area. Compared with T2WI sequences, SWI sequences show a longer, wider range of low signal. Compared with MCAO+SPIO group, MCAO+SPIO-BMSC group can observe that bone marrow mesenchymal stem cells migrate into infarction areas. Prussian blue staining showed that positive cells gathered around the infarction area. Conclusion: MRI techniques can effectively trace mesenchymal stem cells labeled with 50 μg /ml SPIO, monitor migration and therapeutic condition of BMSCs in focal cerebral infarction model, and evaluate the imaging improvement of focal cerebral infarction.]]></description>
<pubDate>Wed,20 Apr 2016 00:00:00  GMT</pubDate>
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<title><![CDATA[A review of the application of MRI techniques in cognitive impairment after traumatic brain injury]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2016.04.013</link>
<description><![CDATA[Traumatic brain injury(TBI) is closely related to a series of complications, among which cognitive impairment is a most common and long-lasting one. Currently, the diagnosis of cognitive impairment after TBI remained mostly by using a neuropsychological method while lacking the evidence of objective brain structure changes, thus affecting the treatment plan and prognosis assessment. In recent years, with the development of new MRI sequence imaging technology, a variety of new MRI sequences can clearly show the micro-structure of the whole brain and brain network. In this review, we mainly summarize the research progress of new MRI sequence in evaluation of cognitive impairment after TBI.]]></description>
<pubDate>Wed,20 Apr 2016 00:00:00  GMT</pubDate>
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<title><![CDATA[Arrhythmogenic right ventricular cardiomyopathy:cardiovascular magnetic resonance update]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2016.04.014</link>
<description><![CDATA[Arrhythmogenic right ventricular cardiomyopathy (ARVC) is a frequent cause of sudden death in the young. Since 1970s, many imaging centers have accumulated much more experience. The purpose of this paper is to provide an overall review of the definition, cardiomyopathy classification update, diagnosis and especially cardiovascular magnetic resonance update on ARVC.]]></description>
<pubDate>Wed,20 Apr 2016 00:00:00  GMT</pubDate>
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