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<title>Chinese Journal of Magnetic Resonance Imaging RSS feed</title>
<link>http://med-sci.cn/cgzcx/en/contents_list.asp?issue=201704</link>
<language>zh-cn</language>
<copyright>An RSS feed for Chinese Journal of Magnetic Resonance Imaging</copyright>
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<title><![CDATA[The principle and prospect of intravoxel incoherent motion imaging]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2017.04.001</link>
<description><![CDATA[The concept of intravoxel incoherent motion (IVIM) imaging has demonstrated that the diffusion-weighted signal can be influenced not only by molecular diffusion but also by microcirculation. It allows a more comprehensive analysis of datas of diffusion-weighted imaging (DWI). In recent years, IVIM has been used in clinical research. It will play an important role in the diagnosis of diseases in various organs and systems.]]></description>
<pubDate>Thu,20 Apr 2017 00:00:00  GMT</pubDate>
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<title><![CDATA[Application of artery spin labeling and intravoxel incoherent motion MR study in the grading of gliomas]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2017.04.002</link>
<description><![CDATA[Objective: To evaluate the diagnostic value of combining 3D artery spin labeling and intravoxel incoherent motion in grading of cerebral gliomas. Materials and Methods: A total of 32 patients with histopathology proved gliomas (13 low grade, 19 high grade) were included in this study. 3D ASL and multi-b IVIM images were retrospectively analyzed. The ASL and IVIM data were processed on workstation to get the CBF and D, D*, f values. The results were compared among high grade and low grade groups and P＜0. 05 was regarded as statistically significant. Results: CBF were significantly higher in high grade gliomas than lower grade gliomas [(75.6±12.3) ml/(100g•min), (55.8±8.9) ml/(100g•min), respectively; P＜0.001]. In bi-exponential IVIM model, the high grade gliomas of D* value also showed significantly higher than lower grade gliomas group [(40.3±23.5)×10-3 mm2/s, (19.2±7.5)×10-3 mm2/s, respectively; P＜0.01)], but there had no difference of D [(0.73±0.26)×10-3 mm2/s, (0.59±0.15)× 10-3 mm2/s, respectively; P＞0.05)] and f (11.1±6.9, 7.2±4.1, respectively; P＞0.05). The area under AUC of combination of CBF and D* for glioma grading was 0.935 and corresponding diagnostic sensitivity and specificity were 91.5% and 89.6%. Conclusion: The combination of 3D ASL and IVIM parameters can be used to differentiate high grade glioma and low grade glioma. Combination of CBF and D* value obtain better diagnostic performance than other parameters.]]></description>
<pubDate>Thu,20 Apr 2017 00:00:00  GMT</pubDate>
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<title><![CDATA[The predictive value of IVIM-DWI on short-term therapeutic effect and prognosis of TACE on hepatocellular carcinoma]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2017.04.003</link>
<description><![CDATA[Objective: To investigate the postoperative early response and short-term prognosis value of intravoxel incoherent motion diffusion-weighted imaging (IVIM-DWI) quantitative parameters for the patients with hepatocellular carcinoma (HCC) treated by transcatheter arterial chemoembolization (TACE). Materials and Methods: Ninety patients with biopsy-proven or clinical diagnostic HCC underwent IVIM-DWI on a 3.0 T MR scanner before TACE, and 90 HCC patients took the same MR scan one month after TACE. The quantitative parameters were measured on the maximal tumor region, including D, D* and f value before and after TACE. The patients were divided into progress group and stable group based on mRECIST as criterion. All data were statistically analyzed. Results: There were significant differences between progress group and the stable group in D and D* values of the tumor before TACE (P＜0.05, respectively). One month after TACE, the ΔD and ΔD* values of the tumor had significant differences between the two groups (P＜0.05, respectively). The D and D* values of tumors had significant differences before and after TACE (P＜0.05, respectively). Conclusion: The D, D* values of the IVIM-DWI could predict the efficacy before TACE in HCC patients. Furthermore, the IVIM-DWI as a noninvasive method might evaluate the early response after TACE in HCC patients.]]></description>
<pubDate>Thu,20 Apr 2017 00:00:00  GMT</pubDate>
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<title><![CDATA[Intravoxel incoherent motion magnetic resonance imaging for evaluating the efficacy of concurrent chemoradiotherapy in nasopharyngeal carcinoma]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2017.04.004</link>
<description><![CDATA[Objective: To explore the value of intravoxel incoherent motion magnetic resonance imaging in evaluating the efficacy of chemoradiotherapy in nasopharyngeal carcinoma (NPC). Materials and Methods: Twenty-seven patients with nasopharyngeal carcinoma proved by biopsy pathology were enrolled. Those patients underwent MRI at the time points of pretreatment (group 1), one month after the start of radiotherapy (group 2) and one month after the end of radiotherapy (group 3). T1WI, T2WI, IVIM (9 b-factors, 0～800 s/mm2) and contrast-enhanced T1WI were included. They received concurrent chemotherapy for 3 cycles during radiotherapy. The apparent diffusion coefficient (ADC) was derived from the mono-exponential model, while the diffusion coefficient (D), perfusion fraction (f) and pseudodiffusion coefficient (D*) were calculated via the bi-exponential model. The values of IVIM parameters and maximum area for NPC lesions were measured at each time point, and their dynamic changes and correlation were analyzed. Results: Patients whose images had artifact were excluded, and 23 patients were included in this study finally. The ADC and D values increased throughout the whole course. ADC value of group 1 and 3 was 0.80×10-3 mm2/s and 1.57×10-3 mm2/s, respectively (P1/3＜0.001); D value of group 1 and 3 was 0.68×10-3 mm2/s and 1.31×10-3 mm2/s, respectively (P1/3＜0.001). f value was increased originally then decreased. f value of group 1 and 2 was 11% and 19% (P1/2＜0.001). There were no correlations between group 1 and group 2, group 1 and group 3, group 2 and group 3 for D* value. Conclusion: IVIM-MRI could monitor dynamic changes of NPC during treatment. ADC value was influenced by microcirculation perfusion, therefore the diffusion of water molecules were overrated. D value was calculated from high b values (＞200 s/mm2), so microcirculation perfusion had little effect on MR signal, it reflected pure diffusion information. D value was better at monitoring the efficacy of chemoradiotherapy. f value might be a potential biomarker.]]></description>
<pubDate>Thu,20 Apr 2017 00:00:00  GMT</pubDate>
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<title><![CDATA[Application of introvoxel incoherent motion sequence in the preoperative T-stage of tongue carcinoma]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2017.04.005</link>
<description><![CDATA[Objective: To investigate intravoxel incoherent motion MR imaging (IVIM--MRI) in the preoperative T-stage of tongue carcinoma. Materials and Methods: According to the T-stage of Head and Neck Neoplasms AJCC (2010 7th), 47 cases of tongue cancer patients were divided into four groups after searching and screening. Both conventional MRI and IVIM sequences were undergone for each patient who was staged. The accuracy of two methods for T staging of tongue cancer was compared with the pathological results. The value of IVIM parameters (pure molecular diffusion coefficient (D), perfusion-related diffusion coefficient (D*), perfusion fraction (f)) were evaluated on tongue cancer preoperative T-stage by using One-Way ANOVA. Results: Estimating of the tumor preoperative T-stage, the accuracy of the IVIM-MRI was 70.2% which was more accurate than routine MRI (48.9%) and that was statistically significant (P＜0.05); The differences of D values in the T-stage groups were statistically significant (P＜0.05), performanced for the differences of D value both in the T1 phase tongue carcinoma and T3, 4 phase, and the T2 phase tongue carcinoma and T4 phase were statistically meaningful (P＜0.05). But the differences of D* and f in the T-stage were not statistically significant (P＞0.05). Conclusion: Compared with routine MRI, IVIM-MRI has certain advantage in differentiating T-stage, and D has a certain value in the preoperative T-stage of tongue cancer.]]></description>
<pubDate>Thu,20 Apr 2017 00:00:00  GMT</pubDate>
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<title><![CDATA[The technology progression of intravoxel incoherent motion on biexponential model]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2017.04.006</link>
<description><![CDATA[Intravoxel incoherent motion (IVIM) is a quantitative method that can be used to noninvasively distinguish tissue diffusivity from perfusion related-diffusion by multiple b values sampling on diffusion-weighted imaging. IVIM biexponential model has not only attracted broad attention, but also been applied in the researches of disease diagnosis and differentiation, evaluation or prediction of therapeutic effect, lesion staging or grading and combination of other imaging patterns. The current research situations and progresses on technology, such as scanning methods, the choice of b value, the repeatability and significance of parameters, and the accuracy of perfusion-related parameters, are mainly discussed in this article.]]></description>
<pubDate>Thu,20 Apr 2017 00:00:00  GMT</pubDate>
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<title><![CDATA[Reduced perfusion in normal appearing white matter in relapsing-remitting multiple sclerosis using 3D pseudocontinuous arterial spin labeling]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2017.04.007</link>
<description><![CDATA[Objective: To investigate whether cerebral blood flow (CBF) is abnormal in normal appearing white matter (NAWM) using 3D pseudocontinuous arterial spin labeling (3D pCASL) and its relationship with clinical data. Materials and Methods: Twenty-nine relapsing-remitting MS (RRMS) and seventeen age, sex-matched healthy control subjects were prospectively and consecutively enrolled and performed MRI including T2 weighted image (T2WI), 3-dimensional Fast Spoiled Gradient Echo (3D FSPGR) and 3D pCASL. Regions of interest (ROIs) in centrum semiovale and periventricular NAWM were manually outlined to obtain the average CBF values. Two independent samples t-test was conducted for comparisons between RRMS and healthy control group in centrum semiovale and periventricular NAWM. Person and Spearman correlation analysis were used to assess the relation between clinical data and CBF values for RRMS group. Results: Compared to healthy control subjects, CBF values were significantly reduced both in centrum semiovale and periventricular NAWM in RRMS (centrum semiovale NAWM: 32.5452±4.5848 vs 35.4865±5.7968, P=0.036; periventricular NAWM: 30.7788±4.1746 vs 34.0530±4.4821, P=0.006). In RRMS group, no relationships were found between CBF values and clinical data (age, age of first onset, onset frequency, disease duration and EDSS score). Conclusion: Our 3D pCASL results showed reduced perfusion in NAWM in RRMS group indicating that there exists potential hemodynamic abnormality in NAWM and hemodynamics may be play a pivotal role in pathogenesis of RRMS patients.]]></description>
<pubDate>Thu,20 Apr 2017 00:00:00  GMT</pubDate>
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<title><![CDATA[Whole tumor volume based histogram analysis of ADC signal intensity for differentitating between WHO grade Ⅱ and Ⅲ glioma]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2017.04.008</link>
<description><![CDATA[Objective: To evaluate the differential diagnostic value of histogram analysis of ADC signal intensity based on entire region of grade Ⅱ and Ⅲ tumor, and then to investigate a potential imaging biomarker to differentiate them. Materials and Methods: Thirteen patients with grade Ⅱ glioma and 20 patients with grade Ⅲ glioma were enrolled in this retrospective study, and all tumors were pathologically confirmed. ROIs containing the entire tumor and peripheral edema were drawn in each slice of the ADC signal intensity maps. Obtained the 3D ROI ADC signal strength histogram information and all its parameters. Histogram related parameters including min intensity, max intensity, mean value, the 10th, 25th, 50th, 75th and 90th percentiles, range, voxel number, standard deviation, variance, mean deviation, skewness, kurtosis and uniformity were recorded. The obtained parameters were compared between groups. Receiver operating characteristic (ROC) curve was constructed to assess the ability of parameters between grade Ⅱ and Ⅲ glioma. Results: Min Intensity (P=0.04), 10th percentiles (P=0.03), voxel number (P=0.003), standard deviation (P=0.022), skewness (P=0.017) showed significant difference between two groups. When optimal cut point of voxel number was 5.46×106 for diagnosis of grade Ⅱ and Ⅲ, the area under the ROC curve was maximum, which was 0.856, the sensitivity and specificity was 81.5%, 80.0%. When optimal cut point of skewness was -1.414, the area under the ROC curve was 0.750, the sensitivity and specificity was 100.0%, 60.0%. When optimal cut point of standard deviation was 14.602, the area under the ROC curve was 0.738, the sensitivity and specificity was 100.0%, 55.0%. Conclusion: Histogram analysis of ADC signal intensity based on entire tumor could provide more information in differentiation of grade Ⅱ and Ⅲ glioma. Voxel number, standard deviation and skewness showed superior diagnostic value.]]></description>
<pubDate>Thu,20 Apr 2017 00:00:00  GMT</pubDate>
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<title><![CDATA[The diagnostic value of ADC combined with DWI in the differentiation of the central neurocytoma and ependymoma]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2017.04.009</link>
<description><![CDATA[Objective: To compare and analyze imaging features of lateral ventricular central neurocytoma (CNC) and ependymoma, exploring the value of DWI and ADC value in differential diagnosis of them. Materials and Methods: The clinical and imaging data of 11 cases of lateral ventricular CNC and 17 cases of lateral ventricular ependymoma pathologically confirmed were collected. All patients underwent conventional MRI scan, enhanced scan and diffusion weighted MRI scan. The results were analyzed in all cases. Results: Eleven cases of lateral ventricular CNC showed equal or slightly higher signal on DWI, and the ADC mean was (0.65±0.12)× 10-3 mm2/s. In 12 from 17 cases of lateral ventricular ependymoma, DWI showed higher or slightly higher signal, 5 cases showed low signal, ADC mean was (1.21±0.24)×10-3 mm2/s, Which was significantly higher than that of CNC (P＜0.001). When optimal cut point of ADC was 0.87×10-3 mm2/s for diagnosis of CNC and ependymoma, the area under the ROC curve was 0.98±0.01, 95% confidence intervals was 0.95—1.00, the sensitivity, specificity and accuracy was 90%, 100%and 90%. Conclusion: The imaging features are helpful in differential diagnosis of lateral ventricular CNC and ependymoma, DWI and ADC values can be applied as a complementary tool in the preoperative diagnosis and differential diagnosis of them, which can increase the diagnostic accuracy.]]></description>
<pubDate>Thu,20 Apr 2017 00:00:00  GMT</pubDate>
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<title><![CDATA[Cerebro-cerebellar functional connectivity in patients with generalized tonic-clonic seizure: a resting state functional MRI study]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2017.04.010</link>
<description><![CDATA[Objective: To explore the altered features of cerebro-cerebellar functional connectivity in resting-state during the interictal time of generalized tonic-clonic seizure (GTCS). Materials and Methods: Nineteen patients with GTCS and 22 age-, sex-, education- and handedness-matched healthy controls (HCs) were recruited. All the individuals' resting-state fMRI data were acquired in a Siemens 3.0 T MR. Firstly, amplitude of low-frequency fluctuations (ALFF) was applied to investigate the changes of whole brain spontaneous functional activity caused by GTCS. Then resting-state functional connectivity (rsFC) was calculated between seeds regions based on ALFF group differences in cerebrum (cerebellum) and all voxels in cerebellum (cerebrum). Finally, the correlation analysis was performed between ALFF/rsFC and NHS3 scores in brain regions with significant group differences. Results: Compared with the HCs, the patients with GTCS exhibit significantly increased ALFF in the right hippocampus, right cerebellar_crus2 and left cerebellar_4_5, but significantly decreased in the right precuneus and left middle frontal gyrus. Seed-based rsFC analysis showed that rsFC in patients with GTCS was significantly increased in the left cerebellar_8, right cerebellar_4_5, and right cerebellar_4_5, but significantly decreased in the left inferior frontal gyrus and right middle temporal gyrus. Furthermore, correlation analysis exhibit the positively correlated between NHS3 scores and rsFC of the left cerebellar_8 (r=0.48, P=0.036) in patients with GTCS, but negatively correlated between NHS3 scores and rsFC of the right middle temporal gyrus (r=-0.34, P=0.042) in patients with GTCS. Conclusion: Cerebro-cerebellar resting-state functional connectivity was abnormal during the interictal time of GTCS, which may be associated with the pathophysiological mechanism and clinical manifestations in patients with GTCS.]]></description>
<pubDate>Thu,20 Apr 2017 00:00:00  GMT</pubDate>
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<title><![CDATA[Prediction of collapse with MRI signs and necrosis volume measurement for non-traumatic osteonecrosis of femoral head]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2017.04.011</link>
<description><![CDATA[Objective: To investigate the clinical value of prediction of collapse in non-traumatic femoral head necrosis and based on the MRI signs and necrotic volume percentages. Materials and Methods: Fifty-six patients (76 hips) were diagnosed as non-traumatic femoral head necrosis without collapse at affiliated Zhongshan Hospital of Dalian University since September 2010 to November 2012. The X-ray examination and MRI scan were performed at the first time examination and follow-up. According to the X-ray image to determine whether collapse or not, divided into collapse group (31 hips) and non-collapse group (45 hips). The bone marrow edema, joint effusion, location of necrotic lesions necrotic morphology and signal feature was analyzed in MRI of the first time examination, and the each quadrant volume and percentage of the femoral head necrosis was measured. By Logistic regression analysis, the risk factors were concluded, and the sensitivity and specificity was determined by ROC curve (receiver operating characteristic curve). Results: There is no significant difference in routine T1 or T2 weighted imaging between the three group. The ADC values of bilateral midfrontal gyrus and superior temporal gyrus cortex significantly increased in groups Ⅰ and Ⅱ compared to groups Ⅲ (P＜0.05). The duration of disease positively correlated with ADC values of the right midfrontal gyrus in group Ⅰ and Ⅱ. Conclusion: The accuracy of prediction of collapse in patients with femoral head necrosis can be effectively improved by using the MRI feature and the measurement of the necrotic volume.]]></description>
<pubDate>Thu,20 Apr 2017 00:00:00  GMT</pubDate>
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<title><![CDATA[The brain mechanism of experimental itch: a Meta-analysis]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2017.04.012</link>
<description><![CDATA[Objective: For a more comprehensive description of the center network processing of itch, a Meta-analysis of neuroimaging was conducted to evaluate the structures activated during experimental itch status. Materials and Methods: Database search was performed in PubMed, Cochrane's library, Wiley Online Library, Springer Link, Science Direct, EMBASE.com, CNKI and Chinese Biomedical Literature Database for literatures published from database establishment to Aguest 2016. We collected the studies on support from functional magnetic resonance imaging (fMRI) in pruritus status according to inclusion and exclusion criteria. The ALE map was created with Ginger-ALE 2.3.6 software and the images were rendered using Mango. Results: Eight studies were identified with a total of 100 subjects. Our Meta-analysis showed that following the itch stimulation, a positive activation was localized in insular, medial dorsal nucleus of thalamus, claustrum, putamen, anterior cingulate, superior frontal gyrus, posterior cingulate, precuneus inferior frontal gyrus, middle frontal gyrus, postcentral gyrus. Conclusion: By integrating the analysis of previous fMRI studies in itch status, we thought that itching impulses pass to the central nervous system by way of the spinothalamic tract, mainly activating postcentral gyrus, precuneus, insula, cingulate cortex, premotor and supplementary motor area, prefrontal area. These brain regions contribut to the encoding of sensory processing, emotional reactions, motion planning and cognitive-evaluative of pruritus.]]></description>
<pubDate>Thu,20 Apr 2017 00:00:00  GMT</pubDate>
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<title><![CDATA[Progresses in magnetic resonance imaging of essential tremor]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2017.04.013</link>
<description><![CDATA[Essential tremor (ET) is one of the most common movement disorder origining from the central nervous system in adults. The pathophysiology of ET remains unclear. Histopathological examination is the most effective method to ascertain the pathophysiology changes. However, the autopsy rate is very low. Magnetic resonance imaging (MRI) provides reliable evidence for the functional-pathological mechanism of ET. The latest progresses in the field of voxel-based morphometry (VBM), diffusion tensor imaging (DTI) and resting-state functional magnetic resonance imaging (rs-fMRI) of ET were reviewed in this paper.]]></description>
<pubDate>Thu,20 Apr 2017 00:00:00  GMT</pubDate>
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<title><![CDATA[Research progress in the evaluation of coronary atherosclerosis plaque by magnetic resonance imaging]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2017.04.014</link>
<description><![CDATA[Coronary atherosclerosis heart disease (CHD) is one of the leading causes of death, and the patients with acute coronary syndrome (ACS) is the main cause of poor prognosis and sudden death. Autopsy pathology shows that vulnerable plaque rupture or erosion of the endothelial surface with thrombus formation is recognized as the most important mechanism of acute coronary syndromes. Magnetic resonance imaging (MRI) is noninvasive, with high reproducibility and perfect soft tissue characterization. After 20 years of hard work, carotid arteries allow identification of plaque morphology using multi-contrast weighted MRI, which has got additional validation studies using histopathologic materials and clinical practice. Although, at present, coronary artery wall imaging is still in the stage of research due to the complexity of imaging technology. In this article, the research progress of magnetic resonance imaging to evaluate coronary artery atherosclerotic plaque is reviewed.]]></description>
<pubDate>Thu,20 Apr 2017 00:00:00  GMT</pubDate>
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<title><![CDATA[Research progress of magnetic resonance imaging in brucellosis spondylitis]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2017.04.015</link>
<description><![CDATA[Brucellosis is a systemic zoonotic infection all over the world, The disease increased every year. It is a systemic infection while the spine is the most affected. Multiplanar capability and superior tissue contrast make magnetic resonance imaging the modality of first choice in evaluation and follow-up of brucellar spondylitis. MRI of brucella spondylitis, the differential diagnosis and IVIM-DWI will be reviewed in this article.]]></description>
<pubDate>Thu,20 Apr 2017 00:00:00  GMT</pubDate>
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