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<title>Chinese Journal of Magnetic Resonance Imaging RSS feed</title>
<link>http://med-sci.cn/cgzcx/en/contents_list.asp?issue=201904</link>
<language>zh-cn</language>
<copyright>An RSS feed for Chinese Journal of Magnetic Resonance Imaging</copyright>
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<title><![CDATA[Modulation of catechol-O-methyltransferase Val158Met polymorphism on topological reorganization of white-matter networks in attention-deficit/hyperactivity disorder children]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2019.04.001</link>
<description><![CDATA[Objective: Attention-deficit/hyperactivity disorder (ADHD) children showed the redistribution of structural connectivity involving large-scale brain systems beyond the prefrontal–striatal model. The dopamine system has been associated with symptoms of ADHD, and is important for pharmacologic treatments. The current study aims to discuss that how dopamine impact neural circuitry underlying behavior pathways occurs in ADHD. Materials and Methods: We used diffusion tensor imaging and deterministic tractography to construct individual white matter structural networks in 40 patients and 40 age-matched healthy control participants. The automated anatomic labeling template was used to parcel the brain into 90 regions of interest to define the network nodes for each subject. The number of connected fibers between each pairs of nodes was calculated and defined as the edge weight between nodes. Catechol-O-methyltransferase (COMT) rs4680 genotyping was performed. All network analyses were performed by using in-house software Gretna. Graph theory approaches were used to investigate the topologic alterations in the structural brain networks between groups and their interaction. We used a network based statistic (NBS) approach to localize specific pairs of regions in which structural connectivity were altered. Finally, the connection strength of linking between hub nodes to hub nodes, hub nodes to nonhub nodes, and nonhub nodes to nonhub nodes were calculated and analyzed between groups. Results: We found significant reorganization of white matter structural networks in ADHD Met allele carriers, manifested as increased nodal degree, nodal efficiency, fronto-striatal circuitry, parietal-cingulum-motor circuitry, feeder and local connections. Conclusions: Those diffuse white matter alterations were not only implicated in fronto-striatal networks mediating executive functions but were also involving in sensorimotor network, frontal, cingulum, and parietal areas during perception-motor, higher order cognitive, attention control and processing. Together, these genetic-based findings highlight large-scale brain systems reorganization in ADHD, might also have important implications on the clinical pharmacologic treatments and development of pharmacogenomics.]]></description>
<pubDate>Sat,20 Apr 2019 00:00:00  GMT</pubDate>
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<title><![CDATA[Application of T2-matrix sequence in the diagnosis of acute lower extremity deep vein thrombosis]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2019.04.002</link>
<description><![CDATA[Objective: To investigate the value of T2 weighted 3D fast spin echo imaging with modulated refocusing flip angles (T2-MATRIX) in the diagnosis of acute lower extremity deep vein thrombosis (LEDVT), and to provide a new imaging method for the early and accurate diagnosis and treatment of LEDVT. Materials and Methods: Twenty-one patients with acute LEDVT were prospectively recruited. T2-MATRIX sequence was performed within 14 days after the symptom onset. Two radiologists performed double-blind interpretation of T2-MATRIX and magnetization preliminary gradient echo sequence (MPRAGE) images on vascular segment level. Two sequences were compared on thrombus length, thrombus area and thrombus signal intensity. MPRAGE and ultrasound were used as the reference to calculate the diagnostic accuracy of T2-MATRIX sequence for the detection of thrombus. Results: A total of 147 vascular segments were detected in 21 patients with acute LEDVT, and thrombi were detected in 67 of these segments. The sensitivity, specificity, positive predictive value, negative predictive value and accuracy of detection of LEDVT in T2-MATRIX at the level of vascular segments were 94.03%, 98.77%, 98.41%, 95.24% and 96.60%, respectively. Intraclass correlation coefficient and bland altman analysis showed that the T2-MATRIX and MPRAGE sequences were highly consistent in the measurement of thrombosis length (P≤0.05), thrombosis area (P≤0.05) and vascular diameter (P≤0.05), with the difference within the consistency boundary accounting for 98.51%, 97.1% and 100%, respectively. Conclusions: T2-MATRIX sequence has a high diagnostic accuracy in the diagnosis of acute LEDVT. Furthermore, surrounding soft tissue edema can also be depicted on the same sequence. It has great potential to become a new imaging method in clinical practice.]]></description>
<pubDate>Sat,20 Apr 2019 00:00:00  GMT</pubDate>
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<title><![CDATA[Effect of PTCD combined with albendazole on liver function and marginal ADC value in patients with end-stage hepatic alveolar echinococcosis]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2019.04.003</link>
<description><![CDATA[Objective: To treat patients with end-stage hepatic alveolar echinococcosis (HAE) jaundice by percutaneous transhepatic cholangial drainage (PTCD) combined with albendazole. The liver function index and the ADC value of the marginal zone were measured. Materials and Methods: Retrospective analysis of 40 cases of patients with obstructive jaundice of end-stage HAE diagnosed in the Department of Hepatobiliary and Pancreatic Surgery in our hospital from 2015 to 2017. The liver function indexes were compared before and after PTCD combined with drug treatment, and the ADC value of the marginal zone were also compared. Results: There were significant differences in ALT, TBIL, DBIL and IBIL between before and after treatment 3, 7, 10 days (P＜0.05). There was no difference on the ADC value of the marginal zone around the lesion between before and after treatment 3 months (P＞0.05), but there was a statistical difference between before and after treatment 6, 10 months (P＜0.05). There was no difference on the ADC value between 6 months and the 10 months after treatment. Conclusions: In patients of obstructive jaundice with end-stage HAE, the liver function index decreased after PTCD and albendazole treatment, and after 6 months the activity of the marginal zone around the lesion tends to be stable.]]></description>
<pubDate>Sat,20 Apr 2019 00:00:00  GMT</pubDate>
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<title><![CDATA[The value of different diffusion models in the depth of myometrial invasion of stage I endometrial cancer]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2019.04.004</link>
<description><![CDATA[Objective: To evaluate the value of monoexponential, biexponential, and stretched exponential diffusion-weighted imaging models in diagnosing the depth of myometrial invasion of stage Ⅰ endometrial cancer. Materials and Methods: 53 cases of stage Ⅰ endometrial cancer were collected, and conventional MRI and multi-b value DWI scan were performed. The apparent diffusion coefficient (ADC), true diffusion coefficient (D) and pseudo-diffusion coefficient (D*) were measured on the pseudo-color map of each parameter, perfusion fraction (f), distribution diffusion coefficient (DDC), water diffusion heterogeneity index (α) value. According to the pathological results after total hysterectomy, it was divided into stage Ⅰa and stage Ⅰb. Differences between the two groups were compared using two independent sample t-tests. The receiver operating characteristic (ROC) curve was plotted to evaluate the efficacy of each parameter in diagnosing the depth of myometrial invasion of stage Ⅰ endometrial cancer. Results: The values of D, f, DDC and ADC in Ⅰb phase were less than Ia, and the differences were statistically significant (P＜0.05). The D* value in Ⅰb phase was greater than that in Ia, the difference was not statistically significant (P＞0.05), Ⅰb phase the α value was less than stage Ⅰa, and the difference was not statistically significant (P＞0.05). The area under the curve (AUC) of D, f, DDC, and ADC values for the diagnosis of myometrial invasion of stage Ⅰ endometrial cancer were 0.867, 0.762, 0.794, and 0.774, respectively. Conclusions: The monoexponential model can help to diagnose the depth of myometrial invasion of stage Ⅰ endometrial cancer. The biexponential, and stretched exponential models are superior to the monoexponential model.]]></description>
<pubDate>Sat,20 Apr 2019 00:00:00  GMT</pubDate>
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<title><![CDATA[Evaluation of microcirculation perfusion in high-risk necrotic femoral head by DCE-MRI]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2019.04.005</link>
<description><![CDATA[Objective: To evaluate the changes of femoral head microcirculation perfusion in high-risk population of femoral head necrosis and the heterogeneity of femoral head blood perfusion in the normal femoral head by DCE-MRI, providing imaging evidence for ultralearly femoral head necrosis. Materials and Methods: Dynamic contrast-enhanced MRI of the hip was performed in 50 adults (a total of 60 cases of femoral head) with 30 cases experimental group who was high-risk patients with osteonecrosis of the femoral head. Another 30 cases of were selected as normal control group. The region of interest (ROI) was selected in the weight-bearing area (anterosuperior), non-weight-bearing area (inferior) and the central area of the femoral head, and the percentage time-intensity curve (TIC) was drawn to read the maximum percentage of enhancement at first pass (fEmax), maximum percentage of enhancement at first pass (Emax), time to peak (TTP) and other related parameters. Comparison of perfusion parameters between different ROI of normal femoral head and corresponding regions of high-risk population of femoral head necrosis by independent sample t-test. Comparison of perfusion parameters between weight bearing areas, non-weight bearing areas and the center of femoral head using analysis of variance. Results: The Emax of ROI in weight-bearing area, non-weight bearing area of the control group was greater than that of high-risk group of femoral head necrosis (P＜0.05). The TTP of ROI in non-load area, centre of high risk group was greater than that of the control group of femoral head necrosis (P＜0.05). Another important finding was that the fEmax, Emax varied widely in the control group. fEmax and Emax were significantly greater for the weight-bearing area, the center area than for the non-weight bearing area (P＜0.01). There was no significant difference in TTP between different ROI in the control group (P＞0.05). Conclusions: The ROI of the patients with high risk of avascular necrosis which was decreased compared with the ROI in corresponding with the normal femoral head; areas with more mechanical load had more blood perfusion. In addition, the perfusion volume of femoral head in high risk population is smaller than that of healthy people. The perfusion time was longer than that of the normal femoral head, and there was blood stasis. Therefore, DCE-MRI can be used to guide clinical practice and prevent avascular necrosis of the femoral head at an early stage.]]></description>
<pubDate>Sat,20 Apr 2019 00:00:00  GMT</pubDate>
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<title><![CDATA[Voxel-mirrored homotopic connectivity in adolescents with internet addiction: A resting-state functional magnetic resonance imaging study]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2019.04.006</link>
<description><![CDATA[Objective: Voxel-mirrored homotopic connectivity (VMHC) was used to study the functional connectivity of cerebral hemispheres in internet addiction(IA) of adolescents. Materials and Methods: Resting state functional magnetic resonance imaging data and structural image data of 18 IA adolescents and 18 matched normal controls were collected, to obtain functional connections based on VMHC. The differences in VMHC values between the groups, the relationship between the mean VMHC values of differential brain regions and weekly online time, and also the diagnostic significance of VMHC for IA were analyzed. Results: The VMHC value of Medial prefrontal lobe was significantly enhanced in IA group (IA group vs. control group: 0.45 vs. 0.29, P＜0.001). The VMHC value was significantly positively correlated with the Internet time of the IA group (r=0.48, P=0.003). The ROC results showed that medial prefrontal lobe mean VMHC value had a certain diagnostic value for IA adolescents (AUC=0.86, Threshold=0.41, sensitivity=72%, specificity=94%). Conclusions: The enhanced VMHC value of medial prefrontal lobe suggests abnormal functional connection between the hemispheres of IA adolescents, and provides objective imaging evidence for IA diagnosis.]]></description>
<pubDate>Sat,20 Apr 2019 00:00:00  GMT</pubDate>
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<title><![CDATA[Neuroimaging of multinodular and vacuolating neuronal tumor]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2019.04.007</link>
<description><![CDATA[Objective: To summarize the clinical, pathologic and imaging characteristics of multinodular and vacuolating neuronal tumors (MVNT) and improve the knowledge about this disease. Materials and Methods: Relevant English literature was reviewed and features of the reported MVNT cases were summarized. Accordingly, the cases with typical imaging findings of MVNT in local database were searched and their clinical and imaging featuers were analyzed. Results:  Until January 2018, there are 87 MVNT with sufficient data had been reported in English literature. Among them, 31 cases were histologically proved. The mean age at presentation was 41(6—71) years old. A female predominance was observed. The clinical presentation included seizures/suspected seizure (1 episode), headache and nonspecific symptoms. Histologically, the MVNT consisted of multinodular tissue, with varying degrees of matrix vacuolization which indicated a dysplastic early neuronal phenotype. The tumors were located principally within the deep cortical ribbon and superficial subcortical white matter. Imaging findings corresponded well with the histologic features. Typical imaging features consisted of a cluster of variably sized nodular lesions located in the subcortical ribbon and superficial subcortical white matter following the gyral contour. They appeared hyperintense on T2WI and FLAIR images, and typically do not enhance or cause mass effect. There are 12 cases of MVNT with typical features identified among about 100 thousand cases in our database. Conclusions: MVNT is a benign lesion with typical histologic and imaging features. With improving knowledge of the features, most of the MVNTs may be diagnosed with neuroimaging without the need of biopsy.]]></description>
<pubDate>Sat,20 Apr 2019 00:00:00  GMT</pubDate>
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<title><![CDATA[Advances in late onset Alzheimer<sup><sup>,</sup></sup>s disease susceptibility genes and their effects on brain structure and function]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2019.04.009</link>
<description><![CDATA[Alzheimer's disease (AD) is the most common type of dementia, which is characterized by progressive memory loss and cognitive decline. To date, APOE is the only known risk gene associated with distributed AD. With the development of genome-wide association studies and magnetic resonance imaging technology, more and more genes have been reported to be associated with AD, brain structure and function, such as Bridging integrator 1, Clusterin etc. However, the pathologic mechanism of these genes in AD is not clear. This paper reviews the action pathway of APOE and other genes and their effects on AD, brain structure and brain function.]]></description>
<pubDate>Sat,20 Apr 2019 00:00:00  GMT</pubDate>
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<title><![CDATA[Application and development of arterial spin labeling techniques in TIA]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2019.04.010</link>
<description><![CDATA[Transient ischemic attack (TIA) is one of the common ischemic cerebrovascular diseases. Some patients will progress to cerebral infarction after TIA and have irreversible neurological impairment. The arterial spin labeling (ASL) can non-invasively evaluate the cerebral perfusion, providing a reliable imaging basis for early diagnosis and treatment of TIA to reduce the incidence of stroke. This article reviews the application and development of ASL in TIA.]]></description>
<pubDate>Sat,20 Apr 2019 00:00:00  GMT</pubDate>
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<title><![CDATA[The research progress of three-dimensional arterial spin labeling in ischemic stroke]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2019.04.011</link>
<description><![CDATA[Three-dimensional arterial spin labeling is a kind of magnetic resonance perfusion weighted imaging technique, which is no need to inject exogenous contrast agents. Compared with the normal two-demensional ASL, there are many superiorities in 3D-ASL, such as the higher signal-to-noise ratio and the faster acquisition speed. One of the scanning parameters of 3D-ASL is post-labeling delay time. The selection of this parameter will affect the accuracy of CBF measurement. Therefore, it is very important to select suitable parameters according to different purpose or different population. 3D-ASL could reflect the cerebral blood perfusion very well, so there is great value of application in the perfusion assessment of ischemic stroke. 3D-ASL can not only help to explore occluded vessels, evaluate ischemic penumbra, predict hemorrhage transformation, but also help to adjust treatment methods and judge prognosis of patients.]]></description>
<pubDate>Sat,20 Apr 2019 00:00:00  GMT</pubDate>
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<title><![CDATA[Research progress in functional magnetic resonance imaging studies on mind wandering]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2019.04.012</link>
<description><![CDATA[Mind wandering, which is a common phenomenon in daily life, refers that individuals transfer the thought processes from the current task activities to the self-generated thoughts and feelings. The cognitive neural mechanism on mind wandering is still unclear. Functional magnetic resonance imaging (fMRI) plays an important role in understanding the cognitive neural mechanisms of mind wandering. This paper presents a systematic review of fMRI studies on mind wandering, focusing on the following aspects: task-related fMRI on mind wandering, the correlation between resting-state fMRI and mind wandering.]]></description>
<pubDate>Sat,20 Apr 2019 00:00:00  GMT</pubDate>
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<title><![CDATA[Magnetic resonance imaging for early diagnosis of neonatal bilirubin encephalopathy]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2019.04.013</link>
<description><![CDATA[Bilirubin encephalopathy (BE) is one of the important causes of severe brain injury in newborns, resulting in severe neurological sequelae. Early accurate diagnosis of acute bilirubin encephalopathy can provide a basis for clinical treatment and help to improve prognosis. At present, it is generally believed that the high symmetry signal of bilateral globus pallidus in conventional, MRI T1WI sequence is characteristic of neonatal acute BE, but the presence of myelin in neonatal period affects signal interpretation, low specificity and high false positive rate. The use of advanced functional magnetic resonance imaging techniques can improve the diagnostic rate of BE, provide an objective basis for the early diagnosis of BE, shed new insights into pathogenesis of neurotoxic brain damage and changes the neural pathway pattern of neurotoxic brain damage caused by hyperbilirubin, such as diffusion-weighted imaging, magnetic resonance spectroscopy, diffusion tensor imaging, and diffusion kurtosis imaging. This article will review the current research progress of early diagnosis of acute bilirubin encephalopathy by magnetic resonance imaging.]]></description>
<pubDate>Sat,20 Apr 2019 00:00:00  GMT</pubDate>
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<title><![CDATA[Progress in the imaging study of solitary fibrous tumors]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2019.04.014</link>
<description><![CDATA[Solitary fibrous tumor is a rare mesenchymal-originated spindle cell tumor that can occur at any part of the body. The imaging features of solitary fibroma are characteristic. However, a definitive diagnosis still depends on pathological and immunohistochemical examination. Most of previous researches reported isolated fibroma in one organ or one part of the body. We summarized the clinical manifestations, imaging and pathological features of the systemic solitary fibroma by comprehensively reviewing the relevant literature of this kind of tumor. The latest research progress is also described.]]></description>
<pubDate>Sat,20 Apr 2019 00:00:00  GMT</pubDate>
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<title><![CDATA[Recent advances in application of Gd-EOB-DTPA MRI in the surveillance for early stage of hepatocarcinogenesis]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2019.04.015</link>
<description><![CDATA[Hepatocellular carcinoma, based on liver cirrhosis, develops via the multistep process of hepatocarcinogenesis. Dysplastic nodule and early HCC, which are at the adjacent stages in the process, are in the high risk for transformation into advanced HCC, thus it is important for these nodules to be early detected and accurately diagnosed. Gd-EOB-DTPA is a hepatocyte specific magnetic resonance imaging contrast agent. It has demonstrated an increased ability of Gd-EOB-DTPA for the detection and higher accurate qualitative diagnosis rate of small liver lesions (＜2 cm, especially＜1 cm) due to its dual performance-extracellular and intracellular contrast agent performance. It benefits early detection of HCC and provides more treatment options with better effectiveness, consequently, prolongs the patient’s survival expectancy and improves the patient’s survival quality. The article aims to summarize, review and focus on the corresponding microscopic pathological and functional changes in the dynamic evolution process of dysplastic nodules and early hepatocellular carcinoma, which can be identified and observed by combining Gd-EOB-DTPA with other MRI sequences for the differential diagnosis and outcome evaluation of liver cirrhosis-associated nodules.]]></description>
<pubDate>Sat,20 Apr 2019 00:00:00  GMT</pubDate>
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<title><![CDATA[The progress of aquaporin magnetic resonance molecular imaging in tumors]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2019.04.016</link>
<description><![CDATA[Aquaporins (AQPs), an intrinsic protein that selectively transports water molecules on the cell membrane, is widely distributed in various tissues throughout the body. Their changes in physiological and pathological state are closely related to the occurrence and development of many diseases, especially the growth, infiltration and metastasis of malignant tumors. Early accurately detecting the distribution and expression level of AQPs in tumor cells can provide more information for preoperative diagnosis, staging and postoperative efficacy evaluation. In recent years, multi b-values diffusion weighted imaging (DWI) based on the theory of AQPs, which reflects the distribution and function of cell membrane AQPs through changes in apparent diffusion coefficient (ADC), has shown great development potential and open up a new field of magnetic resonance (MR) molecular imaging. In this article, we briefly outlined the basic structure, physiological functions, expression and significance of AQPs in tumors, and reviewed the basic principle of AQP-MR molecular imaging and its application in tumors.]]></description>
<pubDate>Sat,20 Apr 2019 00:00:00  GMT</pubDate>
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