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<title>Chinese Journal of Magnetic Resonance Imaging RSS feed</title>
<link>http://med-sci.cn/cgzcx/en/contents_list.asp?issue=201505</link>
<language>zh-cn</language>
<copyright>An RSS feed for Chinese Journal of Magnetic Resonance Imaging</copyright>
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<title><![CDATA[Metabolic concentrations alternations of bilateral prefrontal lobes and hippocampus after taking codeine phosphate: quantified by 1H-MRS and LCModel]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.3969/j.issn.1674-8034.2015.05.001</link>
<description><![CDATA[Objective:  Absolute quantitative analysis of healthy youth in the bilateral prefrontal lobes and hippocampus were performed and offered preliminary stage experimental data, in order to supply a reference for the further study of codeine habituation. Materials and Methods: Twenty right-handed healthy youth were included [10 males, 10 females, mean age (24.9±1.9) years]. MRS data were collected by GE 1.5 T MR scanner, using point resolved selective spectroscopy (PRESS) sequence (TE/TR 30 ms/3000 ms). The regions of interest (ROI) were located over the bilateral prefrontal lobes and hippocampus, size of ROI was 2 cm × 2 cm × 2 cm. The data of spectra were post-processed by LCModel software and the concentrations of metabolites were ultimately measured. The metabolite concentration of each people was analyzed by paired-samples t test of SPSS19.0. Results: After taking codeine phosphate, the concentration of GPC increased 0.254 mmol/L in the left prefrontal lobe while Ins declined 0.988 mmol/L, which reached statistical significance (n=13, P＜0.05. n=12, P＜0.05). The alterations of metabolites in right prefrontal lobe and bilateral hippocampus did not reach statistical significance. Conclusions: The metabolites’ concentrations of the left prefrontal lobes would change with oral codeine phosphate. GPC increased in the left prefrontal lobe while Ins declined, which was considered related with the abatement of neurotransmitter.]]></description>
<pubDate>Wed,20 May 2015 00:00:00  GMT</pubDate>
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<title><![CDATA[Quantitative research of diffusion tensor imaging in cognitive impairment of Parkinson<sup><sup>,</sup></sup>s disease]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.3969/j.issn.1674-8034.2015.05.002</link>
<description><![CDATA[Objectives: To analyze the microstructural white matter changes of Parkinson's disease (PD) patients, study the value of diffusion tensor imaging (DTI) in the diagnosis of  PD with cognitive impairment. Materials and Methods: Thirty PD patients were brought into research, including 18 patients with cognitive impairment (PD-CI) and 12 patients with cognitive normal (PD-CN), at the same time, 30 healthy volunteers were selected as the control group with gender, age, education matched. Conventional MRI and DTI examination were performed between two groups, Hoehn-Yahr (H-Y) and montreal cognitive assessment (MoCA) were evaluated before the MRI exam. On T2WI (b=0) image combined with DTI color coding graph, manually drawing the round region of interest to respectively measure the value of FA and ADC on substantia nigra, red nucleus, globus pallidus, putamen nucleus, the head of caudate nucleus, thalamus, frontal white matter, temporal white matter, parietal white matter, occipital white matter, and statistical analysis were conducted. Results: Compared with the healthy control group, the FA value of substantia nigra, putamen nucleus, the head of caudate nucleus, frontal white matter in PD patients obviously decrease (P＜0.05), the ADC value of frontal and temporal white matter is obviously increase (P＜0.05). There is statistical difference about the ADC value of frontal white matter between groups PD-CI and PD-CN (P＜0.05). The FA and ADC value on each part of patients group have no obvious correlation with H-Y and MoCA scores (P＞0.05). Conclusions: The substantia nigra- striatum loop neurons of PD patients have widespread damage, the injury of frontal white matter is probably key factor of combined cognitive impairment of PD. The appraisal of the microstructural white matter changes by using DTI may be one of the important clues to early diagnosis and illness monitoring about Parkinson's disease.]]></description>
<pubDate>Wed,20 May 2015 00:00:00  GMT</pubDate>
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<title><![CDATA[The study of DTI in bilateral optic radiation in relapsing-remitting multiple sclerosis and relapsing neuromyelitis optica]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.3969/j.issn.1674-8034.2015.05.003</link>
<description><![CDATA[Objective:  To investigate whether there are differences in diffusion tensor imaging (DTI) indexes between relapsing-remitting multiple sclerosis (RRMS) and relapsing neuromyelitis optica (RNMO) in the apparent normal optic radiation by DTI. Materials and Methods: Twenty cases RRMS and RNMO patients and 20 cases age- and sex- matched healthy volunteers received DTI. Fractional anisotropy (FA) value and mean diffusivity (MD) value were acquired on bilateral optic radiation individually, and all RRMS and RNMO patients were evaluated by the expanded disability status scale (EDSS). We compared FA and MD value of bilateral optic radiation in each group using t test. We compared FA and MD value of bilateral optic radiation between each patient group and normal control group using one-way analysis of variance (one-way ANOVA) and Dunnett-t test. To evaluate the association between DTI value and EDSS score we used Spearman. All statistical analyses were conducted using SPSS 17.0. Results: (1) In each group, The bilateral optic radiation FA value (t=0.41, P=0.68. t=0.10, P=0.92. t=0.63, P=0.54) and MD value (t=0.72, P=0.48. t=0.20, P=0.84. t=0.20, P=0.84) were not significantly different (P＞0.05), respectively. FA value (P=0.00. P=0.00) of bilateral optic radiation in patient group was significantly lower than normal control group, while MD value (P=0.00, P=0.00) was significantly higher than normal control group (P＜0.05). FA value (P=0.02) in RNMO patients was decreased than that of the RRMS patients, but the MD value (P=0.50) was not significantly different. (2) There were not correlations between both FA (r=－0.19, P=0.42. r=0.20, P=0.41)  and MD (r=0.11, P=0.64. r=－0.33, P=0.15) values of bilateral optic radiation and EDSS scores (P＞0.05) in RRMS and RNMO. Conclusions: The appearing-normal optic radiation of both RRMS and RNMO patients was involved, but the involvement degree was not consistent in the two groups. FA value has potential applications to identify MS and NMO, as an important biological indicator for monitoring clinical course progress.]]></description>
<pubDate>Wed,20 May 2015 00:00:00  GMT</pubDate>
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<title><![CDATA[Comparative research of computed tomography angiography and magnetic resonance angiography for intracranial aneurysm diagnosis value]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.3969/j.issn.1674-8034.2015.05.004</link>
<description><![CDATA[Objectives: To explore the clinical value of CTA and MRA in diagnosis of intracranial aneurysms by contrast analysis of CTA and MRA examination. Materials and Methods: A retrospective study was conducted by reviewing the DSA, CTA or MRA images records of 60 patientswith suspected intracranial aneurysms. For the 60 patients, 30 patients with CTA and 30 patients with MRA examination. Image post-processing methods include maximum intensity projection (MIP) and volume rendering (VR). DSA diagnosis and arterial aneurysm clipping surgery were regarded as diagnostic criterion for aneurysm to compare the ability of CTA and MRA for intracranial aneurysms manifestation. Results: In 60 cases, a total of 30 aneurysms were confirmed by DSA and surgery, including 16 of 30 aneurysms showed by CTA, and 14 of 30 aneurysms showed by MRA. The sensitivity, specificity, and accuracy of CTA in intracranial aneurysms diagnosis were 93.3%, 86.7%, and 90.0% respectively. For MRA, the sensitivity, specificity, and accuracy in intracranial aneurysms diagnosis were 60.0%, 66.7%, and 63.3% respectively. Conclusions: CTA examination is a fast, safe, and non-invasive method for the effective diagnosis of cerebral aneurysms, and could be the optimal examination for clinical screening of intracranial aneurysms.]]></description>
<pubDate>Wed,20 May 2015 00:00:00  GMT</pubDate>
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<title><![CDATA[The morphological characteristics of prechiasmatic interspace in normal people with MR imaging]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.3969/j.issn.1674-8034.2015.05.005</link>
<description><![CDATA[Objectives: To study and measure the prechiasmatic interspaces on the images in human beings, in order to provide imaging evidence for sellar region neurosurgery operation and basic research for neuroantomy. Materials and Methods: Totally 165 volunteers (87 males and 78 females, age 18 to 80 years, mean  44.6 years), who were divided into three groups by age, young(18—40 years), 60, middle-age (41—60 years), 60 and elderly age group (61—80 years), 45 underwent optic chiasm MR scan with T1 weighted MP-RAGE and T2 weighted TSE sequence. The reconstructed images of axial section parallel with optic nerve were obtained with MPR analysis software on midsagittal images. The length of the intracranial optic nerves and anterior horn of optic chiasma were measured, the area of prechiasmatic interspace was calculated as well. The difference between genders, ages and the left and right intracranial optic nerves were compared. Results: In our studies, mean values of the length of intracranial optic nerves were (18.3±3.3) mm, (18.2±3.1) mm for left and (17.3±3.3) mm for right, (17.6±3.1) mm, (18.3±3.0) mm, (17.3±3.2) mm in young, middle-age and elderly age group. the prechiasmatic interspace was triangular shape for163, trapezoid shape for 2 and its area was (44.7±7.7) mm2, (47.1±6.5) mm2, (45.6±6.9) mm2, (43.7±7.0) mm2 in young, middle-age and elderly age group. the anterior horn of optic chiasm was (72.7±7.4) degree, (69.5±7.9)°, (72.5±7.8)°, (72.3±8.0)° in young, middle-age and elderly age group. All the results did not show significant differences between male and female (P＞0.05). The length of both intracranial optic nerves had statistical significance difference between age groups (P＜0.05). There were no statistically significant difference of the anterior horn of optic chiasm and the area of prechiasmatic interspace between age groups (P＞0.05). There were no statistically significant difference of intracranial optic nerves length between left and right (P＞0.05). Conclusions: The characteristics of the prechiasmatic interspaces and its adjacent anatomical structures can be well shown on MR images and measure and establish reference values of parameters for clinical diagnosis and neurosurgery.]]></description>
<pubDate>Wed,20 May 2015 00:00:00  GMT</pubDate>
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<title><![CDATA[Nasopharyngeal lymphoma on MRI]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.3969/j.issn.1674-8034.2015.05.006</link>
<description><![CDATA[Objective: To study the appearances on MRI imaging of the nasopharyngeal lymphoma (NPL). Materials and Methods: The MRI images of  23 patients with pathologically confirmed NPL were retrospectively analyzed. According to the morphology, the NPL were divided into diffuse infiltrative and focal bump groups. All NPL were assessed for necrosis, local invasion and lymphadenopathy. Results: Fourteen cases were divided into diffuse infiltration group, and 9 cases were divided into focal bump group. Only one patient was observed small patchy necrosis, and the rest were homogeneous on MRI. There was no case present local invasion. Swollen palatine and/or lingual radix tonsil were found in 9. Swollen tonsils were bilateral and symmetrical in 7 cases which come from diffuse infiltration group. Lymphadenopathy was present in 13. Eleven cases, which were bilateral and symmetrical, all come from diffuse infiltrative group. There was no necrosis occurred in all lymphadenopathy. The largest lymph node was located at zone II in 12 cases and zone I in 1 case. Conclusions: There were typical features of NPL on MRI. The lesions at nasopharynx (NP) and lymphadenopathy were homogeneous, infrequent necrosis. Deep structures or the skull base were not involved into. And the diffuse infiltrative group could invade multiple walls of NP, and most of all are bilateral symmetry lymphadenopathy. Bilateral symmetry palate and/or tongue tonsil swollen were complicated by more than half of NPL too.]]></description>
<pubDate>Wed,20 May 2015 00:00:00  GMT</pubDate>
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<title><![CDATA[A comparative study of contrast-enhanced and unenhanced MR pulmonary angiography in the diagnosis of pulmonary embolism]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.3969/j.issn.1674-8034.2015.05.007</link>
<description><![CDATA[Objective:  To evaluate relative detection accuracy of pulmonary embolism (PE) with contrast-enhanced MR angiography (CE-MRA) and unenhanced MR angiography by applying spatial labeling with multiple inversion pulses sequence (SLEEK) imaging. Materials and Methods: Twenty-six patients (15 males and  11 females) with computed tomographic pulmonary angiography (CTPA) diagnosed pulmonary embolism (PE) underwent contrast-enhanced MR pulmonary angiography and SLEEK MR angiography within 48 hours after CTPA. Referring to CTPA, sensitivity, specificity, and positive and negative predictive values for PE detection were calculated and compared for each MR method. Results: Sensitivities for PE detection were 78.8% for contrast-enhanced MR pulmonary angiography and 83.8% for SLEEK MR angiography respectively. Specificities for PE detection were 97.7% for contrast-enhanced MR Pulmonary angiography and 100% for SLEEK MR angiography respectively. Agreement between readers was relatively high (k=0.87). Conclusions: Contrast-enhanced MR pulmonary angiography and SLEEK MR angiography possessed relatively similar sensitivity and specificity. However, considering the non-invasive property of SLEEK MR angiography, where no contrast agent was required, it might become a potential diagnostic strategy for pulmonary embolism.]]></description>
<pubDate>Wed,20 May 2015 00:00:00  GMT</pubDate>
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<title><![CDATA[The value of MRI combined with MRCP in the diagnosis of ampullar area focus]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.3969/j.issn.1674-8034.2015.05.008</link>
<description><![CDATA[Objective:  To assess the value of magnetic resonance cholangiopan-creatography (MRCP) combind with MRI sequence in the diagnosis of ampullar area focus. Materials and Methods: Fifty-one patients with the ampullar area focus, which were examined by MRI combined with MRCP. ERCP, ultrasonography and pathology, and all the reports were compared with other examinations. Conventional MRI includes axil (T1WI, T2WI, T2WI+FS), coronal(T1WI). MRCP examination includes 3D and 2D MRCP examination. Result: MRI combined with MRCP scan demonstrated 4 cases of ampullar cancer, 13 cases of pancreatic head cancer, 9 cases of lower bile duct cancer,1 case of duodenum papilla cancer, 19 cases of calculus, 5 cases of inflammation. Conclusions: MRCP combined with MRI has a high value in the diagnosis and differential diagnosis of ampullar area focus, it can not only demonstrate the location and the range of ampullar area focus, but also can make the degree of straitness and the character clear.]]></description>
<pubDate>Wed,20 May 2015 00:00:00  GMT</pubDate>
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<title><![CDATA[1H MRS quantification of ectopic fat accumulation in pancreas and its relationship with islet beta-cell function in patients with newly diagnosed type 2 diabetes mellitus]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.3969/j.issn.1674-8034.2015.05.009</link>
<description><![CDATA[Objective:  To in vivo quantify the pancreatic fat content in newly diagnosed type 2 diabetes mellitus (T2DM) by applying 1H MRS, and investigate its relationships with liver fat content, serum triglyceride (TG) and islet beta-cell function. Materials and Methods: Fifty-eight T2DM subjects and thirty-two volunteers without T2DM were included in this study. All T2DM subjects were newly diagnosed according to the clinical criteria without any therapy. The pancreatic spectroscopy of at least one location (head, body, and tail) and liver spectroscopy at right lobe were acquired by single-voxel PRESS sequence on 3.0 T MR scanner. The pancreas fat content (PFC) and liver fat content (LFC) were calculated in each case. Spearman correlations between PFC and LFC, TG, the body mass index (BMI), the fasting blood-glucose (FBG), the fasting serum insulin (FINS), the homeostasis model assessment of insulin resistance  (HOMA-IR), the homeostasis model assessment-β (HOMA-β) and the Lee-Bennett islet beta cell function index (MBCI) were performed in order to visualize their relationships. Results: The mean values of PFC in 58 T2DM subjects and 32 volunteers without T2DM were (16.09±6.27)% and (14.56±7.97)%, respectively, there is no statistically difference (P＞0.05). The LFC in 32 T2DM subjects and all volunteers without T2DM was successfully measured, the mean values were (21.13±14.44)% and (12.43±12.19)%, respectively, there was statistically significant differences (P=0.006). Moderate to low correlations were found between PFC and LFC (r=0.502, P=0.003), TG (r=0.467, P=0.007), and BMI (r=0.362, P=0.042) in volunteers without T2DM, but no statistical correlation was found between PFC and LFC, TG, BMI, FBG, FINS, HOMA-IR, HOMA-β, and MBCI (r＜0.15, P＞0.05) in T2DM subjects. Conclusions: No correlation was found between PFC and LPF, TG, and islet beta-cell function in patients with newly diagnosed T2DM.]]></description>
<pubDate>Wed,20 May 2015 00:00:00  GMT</pubDate>
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<title><![CDATA[MRI clinical diagnosis of calf injury]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.3969/j.issn.1674-8034.2015.05.010</link>
<description><![CDATA[Objective: To research the diagnostic value of the gastrocnemius muscle injury and clinical significance of MRI. Materials and Methods: The clinical data of 24 patients with no fractures in the tibia and fibula showed on X-ray were selected, while MRI examination showed that there were injury in the calf. MR examination was performed with phased-array body coil surface, conventional T1WI and T2WI with fat suppression, the scan of the long axis parallel to the tibia and fibula in the sagittal and coronal and auxiliary cross section perpendicular to the long axis of the bone within two weeks after injury. Results: Nine cases of 24 patients were slightly injured (degree Ⅰ), 12 cases of them were moderate injured (degree Ⅱ) and three of them were severely injured (degree Ⅲ). All patients did not have tibia and fibula fractures or bone contusion.specificity 80.6%, this time accurate index was the highest and best diagnostic efficacy. Conclusions: MRI findings in the gastrocnemius muscle damage examination are clear, intuitive and highly accurate so it can be used as clinical diagnosis.]]></description>
<pubDate>Wed,20 May 2015 00:00:00  GMT</pubDate>
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<title><![CDATA[The preliminary exploration of prenatal placenta increta using unenhanced MR imaging under multi-positions and mult-sequences]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.3969/j.issn.1674-8034.2015.05.011</link>
<description><![CDATA[Objective:  To summarize the effective scanning sequences of non enhanced MRI in the diagnosis of placenta accreta by performing multi- positional and multi-sequential non-enhanced MR scanning over 69 cases of prenatal placenta. Materials and Methods: A total of 69 suspicious cases with placenta previa by ultrasound and clinical symptoms were examined by 3.0 T magnetic resonance under 2 positions and 5 sequences. The image quality of different filling bladder state were compared and the imaging findings of placenta increta were analyzed. Preoperative imaging were compared with intraoperative observation and postoperative pathologic results. SPSS16.0 statistical software was used for statistical analysis. Result: The image quality of 69 cases could meet the demand of diagnosis. The preoperative diagnosis was consistent with pathology and postoperative diagnosis. The quality of imaging were improved by two positions and patient discomfort was reduced, the artifact and volume effect was reduced by bladder different filling state. Compared with postoperative pathologic results, the diagnosis sensitivity, specificity and accuracy of placenta increta under multi-positions and multi-sequences was respectively 96.7%(58/60), 77.8% (7/9) and 95.7% (66/69). The diagnosis sensitivity of penetrative placenta under combination of supine position and lateral position was 66.7% and was higher than that of the single supine position (33.7%). Conclusions: Different bladder filling state with position change can effectively reduce the artifact and volume effect and improve the imaging quality. The unenhanced MR scanning imaging under 2 positions and 5 sequences can provide abundant diagnostic information and treatment information for the placenta previa and provide a significant role in the clinical diagnosis and treatment.]]></description>
<pubDate>Wed,20 May 2015 00:00:00  GMT</pubDate>
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<title><![CDATA[Study of a new method for imaging of GABA based on chemical exchange saturation transfer using a 7.0 T MR scanner]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.3969/j.issn.1674-8034.2015.05.013</link>
<description><![CDATA[Objective: γ-aminobutyric acid (GABA) is an important inhibitory neurotransmitter in the brain. In this study, we developed a novel MRI technique to measure GABA based on chemical exchange saturation transfer (CEST). Materials and Methods: All the MRI studies were performed in a 7.0 T Agilent MRI scanner. Z-spectra of GABA and other metabolites (glutamate, myo-inositol, creatine and choline) were acquired at 37° and pH 7.0, respectively. CEST images of phantoms with different concentrations of GABA solutions and other metabolites were collected to investigate the concentration dependent CEST effect of GABA and the potential contributions from other brain metabolites. Results: The CEST effect of GABA was observed at 2.75 ppm downfield from bulk water. The CEST effect of GABA increased with B1 amplitude and kept steady after the B1 reached 6.0 μT. The CEST effect of GABA was proportional to the GABA concentration in vitro. Except for a small contribution from glutamate, all other metabolites contributed negligible CEST effects to GABACEST at 2.75 ppm. Conclusions: These findings demonstrate the feasibility and potential to map changes in GABA concentration using CEST with a optimal B1 amplitude, which has excellent spatial and temporal resolution.]]></description>
<pubDate>Wed,20 May 2015 00:00:00  GMT</pubDate>
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<title><![CDATA[Progresses of functional magnetic resonance imaging in renal fibrosis]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.3969/j.issn.1674-8034.2015.05.014</link>
<description><![CDATA[Renal fibrosis can lead to renal failure, it is a common outcome of end-stage chronic kidney disease, and the most common cause of kidney transplant failure. Therefore, the degree of renal fibrosis is closely related to the prognosis and patients. Although some methods can inspect renal fibrosis and renal insufficiency well, none of them can non-invasively detect renal fibrosis in vivo perfectly. Recently, more and more researches about renal fibrosis and renal insufficiency diagnosis by functional MRI were reported. This paper reviews and analyzes some functional MRI progresses about renal fibrosis in the past few years.]]></description>
<pubDate>Wed,20 May 2015 00:00:00  GMT</pubDate>
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<title><![CDATA[The application progess of magnetic resonance imaging in prognosis of patients with glioblastoma]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.3969/j.issn.1674-8034.2015.05.015</link>
<description><![CDATA[Glioblastoma multiforme (GBM) is the most common form of primary brain cancer and the most malignant neoplasm with predominant astroytic differentiation. The patient with GBM has met the difficulty of complicated treatment, high morbidity and mortality, and short mean lifetime after surgery during the clinic work. There are many influencing factors related to the prognosis. Magnetic resonance imaging (MRI) provides information to assist clinicians in making important decisions of treatment plan, and has been respected in the matter of morphologic analysis before the surgery, supervision and analysis of the effect of treatment. It is considered that MRI can do some prediction of the patients with GBM by using different sequence of MRI with index like scoup of the tumor, necrosis and edema.]]></description>
<pubDate>Wed,20 May 2015 00:00:00  GMT</pubDate>
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