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<title>Chinese Journal of Magnetic Resonance Imaging RSS feed</title>
<link>http://med-sci.cn/cgzcx/en/contents_list.asp?issue=201905</link>
<language>zh-cn</language>
<copyright>An RSS feed for Chinese Journal of Magnetic Resonance Imaging</copyright>
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<title><![CDATA[Texture analysis of 3D-arterial spin labeling imaging in glioma grading: a pilot study]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2019.05.001</link>
<description><![CDATA[Objective: To explore the value of texture analysis based on ASL images in evaluating the heterogeneity of glioma and peritumoral edema. Materials and Methods: Eighty-one patients with glioma, confirmed by pathology, were enrolled from January 2016 to June 2018. These patients underwent routine MRI and 3D-ASL preoperative. There were 31 cases of low-grade gliomas and 50 cases of high-grade gliomas. The Max layers of tumor parenchyma and peritumoral edema were delineated on ASL gray scale images as region of interest (ROI) respectively. The histogram and gray level co-occurrence matrix texture analysis were performed using Omni-Kinetics software. Thirty-two texture feature parameters of ASL gray scale images were measured. Compare the differences of texture parameters between high grade and low grade gliomas for tumor parenchyma and peritumoral edema by unpaired student’s t-test or Mann-Whitney U test. ROC curves for statistically significant parameters were used to evaluate their efficacy. Results: Twenty-one texture parameters of tumor parenchyma had significant difference between high and low grade gliomas (P＜0.05), while 19 texture parameters of peritumoral edema had significant difference (P＜0.05). Receiver operating characteristic (ROC) were plotted , and showed that uniformity and energy of tumor parenchyma of AUC was 0.71 (95%CI: 0.59—0.8), 0.72 (95%CI: 0.59—0.85), the critical value was 0.81, 3.21×10-2, the sensitivity was 48.4%, 61.3%, the specificity was 92.00%, 92.00%, the positive predictive values was 78.9%, 82.6%, and the negative predictive values was 74.2%, 79.3%, respectively. The min intensity of peritumoral edema of AUC was 0.72 (95%CI: 0.60—0.85), the critical value was 30, the sensitivity was 84%, the specificity was 58.14%, the positive predictive value was 53.8%, and the negative predictive value was 86.0%. Conclusions: Texture analysis based on ASL images can provide more quantitative information, which is valuable for evaluating the heterogeneity of tumor parenchyma and peritumoral edema of gliomas.]]></description>
<pubDate>Mon,20 May 2019 00:00:00  GMT</pubDate>
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<title><![CDATA[The diagnostic value of multi b-values diffusion weighted imaging in the genotypes of WHO grade Ⅱ—Ⅲ astrocytomas]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2019.05.002</link>
<description><![CDATA[Objective: To investigate the value of multiple b-values diffusion weighted imaging (DWI) in predicting the genotype of isocitrate dehydrogenase1 (IDH) in WHO grade Ⅱ—Ⅲ astrocytomas. Materials and Methods: Patients' data of WHO grade Ⅱ—Ⅲ astrocytomas with IDH genetic information were collected. All routine magnetic resonance imaging (MRI) and multiple b-values DWI were performed before surgery. Measuring the parameters of the astrocytoma's parenchyma and the contralateral normal brain's parenchyma: aquaporines related diffusion coefficient (AQP-ADC), true diffusion coefficient (D), perfusion related diffusion coefficient (D*) and perfusion fraction (f). Then calculate the calibrated parameters (tumor parameters values divided by parameters values measured in the contralateral normal brain's parenchyma): relative AQP-ADC (rAQP-ADC), relative D (rD), relative D* (rD*), relative f (rf). A t-test of two samples was used to analyze the difference in parameters between different gene states, and the receiver operating characteristic (ROC) curve was plotted to calculate the threshold, sensitivity and specificity. Results: For astrocytomas, the rD value of IDH mutation group was higher than the IDH wild-type, while the D* value, rD* value and rf value of the mutation group were lower than the wild type, the difference was statistically significant (P＜0.05). The area under the ROC curve, the threshold, the sensitivity and the specificity of the rD were 0.706, 1.839, 64.71%, 80.00%. The D* were 0.814, 0.00267, 88.24%, 66.67%. The rD* were 0.759, 0.969, 58.82%, 93.33%. The rf were 0.710, 1.875, 88.24%, 53.33%. Conclusions: Multi b-values DWI has certain application value for diagnosis of IDH genotype in WHO grade Ⅱ—Ⅲ astrocytomas. The values of D* and rf are more sensitive to diagnose the genotypes of astrocytoma, while the value of rD* has higher specificity.]]></description>
<pubDate>Mon,20 May 2019 00:00:00  GMT</pubDate>
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<title><![CDATA[The differences of DRD2TaqIA genotype on functional connectivity of insula in heroin addicts undergoing methadone maintenance treatment: a resting-state fMRI study]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2019.05.003</link>
<description><![CDATA[Objective: This study aimed to explore the differences and significance of whole brain functional connectivity (FC) seeding as insula between heroin addicts undergoing methadone maintenance treatment (MMT) with different DRD2TaqIA genetic variants by a functional connectivity method. Materials and Methods: Twenty-seven male MMT carrier A1 allele (A+ group) and 20 age, education, smoking matched homozygous A2 allele males MMT (A- group) participated in this study. Rest-state functional MRI was performed with 3.0 T scanner. The abstinent time was defined by the monthly structure interview and urine test in the subsequent 12 nomths after the MRI scan. The MRI data analysis was conducted by the toolbox DPABI. The whole brain FC seeding as bilateral insula was obtained in group A+ and group A-. Next, intergroup differences of the insula FC was calculated with two-sample t test. Moreover, the partial correlation between abstinent time after the MRI scan and the intensity of FC which is intergroup significantly different was analyzed. Results: Compared with A- group, A+ group showed reduced FC between the right insula and the bilateral dorsolateral prefrontal cortex, and the bilateral caudate nucleus (cluster size ＞5, FDR correction, P＜0.001). In addition, FC intensity between the right insula and the right dorsolateral prefrontal cortex had a positive correlation with abstinent time (r=0.378, P=0.011. Bonferroni correction P＜0.05). Conclusions: There were significant differences in insular functional connectivity feature between heroin addicts undergoing methadone maintenance treatment (MMT) with different DRD2TaqIA genetic variants. It might one of the important pathway that the insula regulation of inhibitory control function and reward neural circuit, through which DRD2TaqIA genotype influence on relapse behavior in MMT.]]></description>
<pubDate>Mon,20 May 2019 00:00:00  GMT</pubDate>
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<title><![CDATA[Impairments of cerebral cortex and subcortical nucleus in cerebral hepatolenticular degeneration: magnetic resonance imaging study]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2019.05.004</link>
<description><![CDATA[Objective: To explore the damages of brain gray matter in patients with cerebral hepatolenticular degeneration. Materials and Methods: Brain 3D T1 weighted images were obtained from 30 patients with untreated cerebral hepatolenticular degeneration. One-way ANOVA was used to analyze group difference. Cortical gray matter and deep nucli volumes were analyzed using FMRIB Software Library (FSL) software and voxel based morphometry (VBM). Thirty healthy volunteers were enrolled as controls. Results: Compared with controls, the percentages of each cortical lobe atrophy and the comparison of bilateral cortical lobes were as follows: cerebellum (left 16.48% ＜ right 16.54%, P＞0.05), frontal cortex (left 23.6% ＞ right 19.5%, P＜0.001), temporal cortex (left 16.9% ＜ right 25.4%, P＜0.001), parietal cortex (left 15.5% ＜ right 16.1%, P＜0.001), occipital cortex (left 21.0% ＜ right 27.2%, P＜0.001), and insular cortex (left 58.7% ＞ right 49.2%, P＜0.001). The volumes of the brainstem and deep gray matter nuclei except the amygdale were significant atrophy. Atrophy percentage arranged in descending order was the accumbens nuclei, putamen nuclei, globus pallidus, thalamus, caudate nuclus, and brain-stem. There were no significant difference in the percentage of atrophy in each nucleus between the hemispheres. Conclusions: Cerebral hepatolenticular degeneration was characterized by bilaterally non-symmetrical cortical atrophy and symmetrical deep gray matter atrophy.]]></description>
<pubDate>Mon,20 May 2019 00:00:00  GMT</pubDate>
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<title><![CDATA[Comparison of intraoperative magnetic resonance imaging, ultrasound and fluorescence guided with 5-ALA in the diagnosis of residual glioma: a Meta-analysis]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2019.05.005</link>
<description><![CDATA[Objective: To evaluate the value of intraoperative magnetic resonance imaging, intraoperative ultrasound and intraoperative fluorescence guided with 5-aminolevulinic acid (5-ALA) in the diagnosis of residual glioma. Materials and Methods: Literatures on intraoperative MRI, intraoperative ultrasound and 5-ALA in the diagnosis of residual glioma were collected from Pubmed, Embase, the Cochrane Library, CNKI and Wanfang Database from the establishment of the database to April 2018. Two researchers independently screened the literature according to inclusion and exclusion criterias, and used QUADAS-2 to evaluate the quality of the included literatures. The sensitivity (Sen), specificity (Spe), positive likelihood ratio (PLR), negative likelihood ratio (NLR), diagnostic ratio (DOR) were analyzed by Meta-Disc 1.4 and Stata 13.0 software. The heterogeneity was tested and the summary receiver operating characteristic curve (SROC) was calculated. Results: Thirty-four papers were included and analyzed by random effect model. The Sen, Spe, PLR, NLR and DOR of iMRI, iUS and 5-ALA were 0.698 (0.651, 0.742), 0.819 (0.762, 0.867), 3.815 (2.208, 7.175), 0.230 (0.110, 0.484), 22.556 (5.657，89.933). 0.746 (0.717, 0.773), 0.872 (0.850, 0.892), 4.041 (2.588, 6.310), 0.313 (0.227, 0.433), 15.951 (8.190，31.068). 0.752 (0.726, 0.777), 0.862 (0.839, 0.882), 3.877 (2.593, 5.798), 0.313 (0.230, 0.425), 15.256 (8.309，28.046). The AUC of iMRI, iUS, 5-ALA were 0.897, 0.865, 0.891. There were no significant statistical significance by Z test. Conclusions: iMRI, iUS, 5-ALA have important diagnostic value for the diagnosis of residual tumor after glioma resection. iMRI and iUS can provide important imaging information of tumor resection, peripheral edema, hematoma, etc. The AUC of iMRI is slightly higher than that of iUS, 5-ALA.iMRI could provide real-time information of the overall brain hemorrhage and edema in the operation. The specificity of iUS is slightly higher than the other two technologies, and it can reduce the rate of misdiagnosis. It can make great dianostic significance in the functional area of glioma surgery. The sensitivity of 5-ALA is higher, which can reduce the rate of missed diagnosis. However, there is a certain deficiency in brain function imaging. So it cannot completely replace iMRI and iUS. At present, the combination of multiple imaging techniques in the operation plays a great role in glioma resection, which can greatly improve the accuracy of neurosurgery.]]></description>
<pubDate>Mon,20 May 2019 00:00:00  GMT</pubDate>
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<title><![CDATA[MRI diagnosis of nonspecific granulomatous lobular mastitis]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2019.05.006</link>
<description><![CDATA[Objective: To explore the imaging features of non-specific granulomatous lobular mastitis (IGM) on MRI and to improve the understanding of the disease. Materials and Methods: Twenty cases of IGM confirmed by pathology were collected. According to the breast imaging reporting and data system (BI-RADS-MRI) of 5th edtion, T2WI, diffusion weighted imaging (DWI), dynamic enhanced scan distribution and internal enhancement characteristics, time-signal curve (TIC) of IGM were observed and recorded. Then reserved the comprehensive analysis of MRI performance characteristics of IGM. Results: IGM showed mass enhancement in 1 case with circumscribed margin and rim enhancement. There were 19 cases of non mass enhancement. The apparent diffusion coefficient (ADC) value in the non-abscess forming area was (0.93±0.15)×10-3 mm2/s. They mainly appeared regional distribution (11/19, 57.9%) and segmental distribution (6/19, 31.6%). The internal enhancement characteristics was mainly inhomogeneous enhancement (14/19, 73.7%) and the aspect ratio was 1.73±0.66. There were 17 cases accompanied by micro-abscess. Conclusions: IGM has a relatively characteristic appearance on MRI. The formation of micro-abscess is more valuable to the diagnosis of this disease. The correct understanding and diagnosis of IGM can provide valuable reference for the clinical diagnosis and treatment.]]></description>
<pubDate>Mon,20 May 2019 00:00:00  GMT</pubDate>
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<title><![CDATA[Three dimensional fast spin echo accelerated with compressed sensing diagnoses cartilage lesions in knee]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2019.05.007</link>
<description><![CDATA[Objective: To explore the diagnostic performance of modulated flip angle technique in refocused imaging with extended echo train (MATRIX) which is a three dimensional fast spin echo accelerated with compressed sensing for cartilage lesions of the knee joint. Materials and Methods: Sixty-two knee joints in 62 patients with knee joint injury were examined at 3.0 T magnetic resonance imaging (MRI) system before arthroscopic operation. Following conventional two dimensional fast spin echo (2D FSE) protocol, MATRIX including sagittal fat-suppressed proton density weighted image (PDWI) and non-fat-suppressed T1-weighted image (T1WI) was performed. And then axial and coronal images were reformatted after MATRIX scanning. 2D FSE and MATRIX images were independently reviewed by two radiologists. Signal to noise ratio (SNR) and contrast to noise ratio (CNR) of cartilage in 2D FSE and MATRIX images were calculated. Two radiologists independently graded cartilage lesions according to ICRS grade system, and then sensitivity, specificity and accuracy of 2D FSE and MATRIX were calculated with arthroscopy as the reference standard. Statistic analysis was performed with paired t test and McNemar test. Results: SNR of cartilage and CNR of cartilage/fluid and cartilage/marrow in MATRIX were significantly higher (P＜0.01) than these in conventional 2D FSE. The sensitivity, specificity and accuracy of MATRIX and 2D FSE for diagnosing cartilage lesions were respectively 70.8%/59.2%, 75.5%/84.2% and 74.1%/76.6%. MATRIX had significantly higher sensitivity (P＜0.01) but  lower specificity (P＜0.01) than 2D FSE. There was no significant differences (P=0.067) in accuracy between two sequences. Conclusions: MATRIX has significantly higher SNR and CNR for cartilage, and provides higher sensitivity but lower specificity for diagnosing cartilage lesions compared to conventional 2D FSE.]]></description>
<pubDate>Mon,20 May 2019 00:00:00  GMT</pubDate>
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<title><![CDATA[Quantitative study of spinal tuberculosis by HISTO and DWI sequences]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2019.05.008</link>
<description><![CDATA[Objective: To explore the selection of high-speed multi-echo T2 corrected multicho at 1H MR Spectroscopy (HISTO) and diffusion weighted imaging (DWI) and ROI setting methods for quantitative study and analysis of FF%, R2water and ADC values in patients with spinal tuberculosis. Materials and Methods: Fifty vertebral bodies of 17 patients with spinal tuberculosis and 50 vertebral bodies of 17 healthy volunteers. HISTO and DWI sequence scanning, HISTO sequence will automatically draw the curve according to the region of interest selected before scanning and calculate the area under the curve. The DWI sequence selects the lesion vertebral body and adjacent normal vertebral body area by the same area unit on the fitted ADC map. The affected vertebral disc and healthy volunteers were the region of interest, and the ADC values were obtained. Results: the fat and R2water values of the lesion vertebral body and normal vertebral body in the HISTO sequence were: fat (19.90±12.59), (44.15±8.30) and R2water (26.12±8.94), (37.95±4.35); The ADC values of the vertebral body, the lesion near the normal vertebral body, the lesion jumping 2 normal vertebral body and the healthy volunteer vertebral body, the affected intervertebral disc and the healthy volunteer disc in the DWI sequence were (1.05±0.25), (0.39±0.18) and (0.38±0.20), respectively, (0.35±0.11), (0.38±0.20) and (1.94±0.16), (1.73±0.14), on the HISTO sequence, the lipid peak is on the left, the water peak is on the right, the lipid peak of the lesion is reduced, the area under the curve is less, the water peak becomes higher and narrower, the R2water value is reduced, and the FF% value is reduced compared with the R2water value. The fat content and R2water value of the body were statistically significant (P＜0.05) with the fat content and R2water value of the healthy volunteers. DWI sequence of spinal tuberculosis lesions vertebral body and lesion adjacent vertebral body, lesion jumping 2 vertebral bodies and healthy volunteer vertebral body and affected intervertebral disc and healthy volunteer intervertebral disc have statistical significance (P＜0.05). Conclusions: Quantitative analysis shows that HISTO and DWI imaging can better complement conventional MRI in diagnosis and differential diagnosis of spinal tuberculosis.]]></description>
<pubDate>Mon,20 May 2019 00:00:00  GMT</pubDate>
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<title><![CDATA[Comparative study of image quality between synthetic MRI and conventional MRI]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2019.05.009</link>
<description><![CDATA[Objective: Compare the image quality between Synthetic MRI and conventional MRI of the brain by assessment of image contrast, noise level and artifact, and further investigate the differences of diagnostic quality. Materials and Methods: Retrospectively reviewed 30 patients who had synthetic MRI added to conventional MRI scan from Apr to Nov 2018. Images of T1FLAIR, T2WI, T2FLAIR were compared in two different ways: visual grading scale and measurement. Visual imaging quality were rated in 5 scales according to the 4 criteria: gray and white matter interface, margin of the lesion, noise level and artifact. In each patient, 12 regions of interest were placed in the brain image, which included the gray matter, white matter and cerebral spinal fluid. The image contrasts were calculated and compared from the differences of signal intensities measured from 12 different ROIs. Results: Synthetic T1FLAIR, T2WI and T2FLAIR generally had higher signal intensity than conventional MRI (P＜0.01). Synthetic T1FLAIR had higher contrast between gray matter, white matter and cerebral spinal fluid than conventional T1FLAIR (P＜0.01). Synthetic T2WI had similar contrast between gray matter and white matter with conventional T2WI (P＜0.01), and had lower contrast between gray matter and cerebral spinal fluid (P＜0.01) as well as white matter and cerebral spinal fluid (P＜0.01). Synthetic T2FLAIR had similar contrast between gray matter and white matter, and had higher contrast between gray matter and cerebral spinal fluid (P＜0.01) as well as white matter and cerebral spinal fluid (P＜0.01). Synthetic MRI had higher level of noise and artifact, especially on T2FLAIR. The conspicuity of white matter focal cerebral ischemia were higher in the Synthetic T1WI and Synthetic T2WI but the interfaces between gray matter and white matter were less clear in Syn MRI. Conclusions: Synthetic MRI has similar or higher image contrast between gray matter and white matter, and has higher lesion conspicuity than conventional MRI. Synthetic MRI image quality is perceived to be inferior, especially in T2FLAIR. Extra conventional T2FLAIR could be added to synthetic MRI in clinical work.]]></description>
<pubDate>Mon,20 May 2019 00:00:00  GMT</pubDate>
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<title><![CDATA[The clinical value of 3D-T1WI modulated flip angle technique in refocused imaging with extended echo train technology in diagnosis of deep venous thrombosis]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2019.05.010</link>
<description><![CDATA[Objective: To investigate the clinical value of 3D-T1WI modulated flip angle technique in refocused imaging with extended echo train (MATRIX) sequences in diagnosis of deep venous thrombosis (DVT). Materials and Methods: In this prospective study, 20 patients clinically were diagnosed with deep venous thrombosis using ultrasound and D-dimer test from February 2018 to October 2018 in our hospital. 3D-T1WI-MATRIX and 3D-T1WI magnetization prepared rapid acquisition gradient echo (MPRAGE) were scanned by United Imaging uMR 770 3.0 T MRI system. The image quality of two sequences were evaluated with signal-to-noise ratio (SNR) and thrombosis vs blood contrast-to-noise ratio (CNR), and observed by two experienced radiologists through the demonstration and artifact of the venous thrombosis and the anatomical structure in five MPR axial pieces in inferior vena cava, common iliac vein, external iliac vein, upper femoral vein and middle-lower femoral vein among two sequences using five-point scale. Using SPSS 21.0 for statistical analysis. Results: In 20 cases of DVT patients, the SNR and CNR in 3D-T1WI-MATRIX were 117.20±65.40, 194.28±191.58, while the SNR and CNR in 3D-T1WI-MPARGE were 65.23±34.67, 57.24±54.38. The differences between them were statistically significant (P＜0.05). The subjective image quality score among the two radiologists showed statistically significant differences in inferior vena cava, common iliac vein, external iliac vein, and middle-lower femoral vein in two sequences (P＜0.05). there was no significant difference in upper femoral vein (P＞0.05). Conclusions: As a black-blood sequence, 3D-T1WI-MATRIX is a new technique which has better SNR and CNR, less artifacts compared to 3D-T1WI-MPARGE which shows great value for DVT diagnosis.]]></description>
<pubDate>Mon,20 May 2019 00:00:00  GMT</pubDate>
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<title><![CDATA[Evaluation of liver fibrosis in rats by magnetic resonance intravoxel incoherence imaging]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2019.05.011</link>
<description><![CDATA[Objective: To evaluate the diagnostic value of intravoxel incoherent motion (IVIM) in the evaluation of liver fibrosis in rats. Materials and Methods: SPF SD rats were randomly divided into experimental group (55) and control group (11). The experimental group was established with hepatic fibrosis model. From the 2nd to the 12th week, 5 rats in the experimental group and 1 in the control group were randomly selected for MR scanning, and the METAVIR stage for diagnosis and diffusion weighted imaging (DWI) and IVIM parameter values were measured during the same period. SPSS 22.0 was used to analyze the correlation, diagnosis, and staging value of DWI and IVIM parameters with liver fibrosis stages. Results: (1) Four deaths and poor quality of 6 scanned images were excluded during modeling in the experimental group, and 45 experimental mice were eventually included. The pathological results: F1 to F4 were 8, 13, 14 and 10 respectively, and 11 of the control group were F0. (2) ADC, D*, and f were lower in the experimental group than in the control group (P＜0.01). Spearman analysis showed that ADC, D, f, and D* were negatively correlated with liver fibrosis levels (P＜0.05). (3) The ADC, D, f, D* values decreased with the progression of hepatic fibrosis, and the ADC of F3 and F4 were significantly different. D* of F0 and F1, D* and f of F1 and F2, and D of F3 and F4 were significantly different (P＜0.05). The receiver operating characteristic (ROC) curve showed that D* identified F0 and F1—F4, F0—F1 and F2—F4, and F0—F2 and F3—F4 were better than ADC, D and f. ADC identified F0—F3 and F4 as the most efficient. Conclusions: D* discriminates F0—F3 with the highest efficiency, and ADC discriminates F0—F3 and F4 with the highest efficacy. D*, ADC have liver fibrosis staging application value.]]></description>
<pubDate>Mon,20 May 2019 00:00:00  GMT</pubDate>
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<title><![CDATA[Advances in magnetic resonance diffusion kurtosis imaging study of common mental disorders]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2019.05.013</link>
<description><![CDATA[The current diagnosis of mental disorders is mainly dependent on the clinical manifestations, and no clear biological indicators have been found so far. Diffusion kurtosis imaging (DKI) is one of the diffusion magnetic resonance imaging, reflecting the non-Gaussian diffusion characteristics of water molecules in the tissue, can reflect the microstructural changes more truly and subtly, can be independent of the spatial position of the tissue, at the same time, export standard diffusion tensor imaging (DTI) parameters and DKI parameters. DKI technology has found changes in the microstructure of gray matter and white matter in the study of mental disorders (schizophrenia, depression), which is helpful for the study of its neuropathophysiological mechanisms. This article proposed to summary the technic principles and aplication advances in common mental disorders for DKI.]]></description>
<pubDate>Mon,20 May 2019 00:00:00  GMT</pubDate>
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<title><![CDATA[Research processing of multimodal MRI in migraine]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2019.05.014</link>
<description><![CDATA[Migraine is a common type of primary headache disorder with high prevalence in the general population, characterized by paroxysmal attacks of typically unilateral or bilateral throbbing headache. The pathogenesis of migraine is still not clear, neuroimaging contributes much to investigating the mechanism of migraine attacking. Multimodal MRI can be used in migraine research by comprehensive analysis of the morphology, function, and metabolic status of the site. This review summarizes recent brain structural and functional imaging findings in migraine.]]></description>
<pubDate>Mon,20 May 2019 00:00:00  GMT</pubDate>
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<title><![CDATA[The states in multimodality MRI of methamphetamine induced psychosis and potential neural underpinnings]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2019.05.015</link>
<description><![CDATA[Methamphetamine has become the most popular abused drug in China, and the methamphetamine-associated psychosis (MAP) has become one of the important factors which endangering public safety. Despite the neuroimaging studies found that methamphetamine use disorder is associated with the altered brain structure and function, only a few studies focused on MAP. This paper is to review the methamphetamine induced psychosis and further progression of brain in multimodality MRI.]]></description>
<pubDate>Mon,20 May 2019 00:00:00  GMT</pubDate>
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<title><![CDATA[The basic principle of ASL technology and its research progress in vascular cognitive impairment]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2019.05.016</link>
<description><![CDATA[Vascular cognitive impairment (VCI) is a group of syndromes ranging from mild cognitive impairment to dementia. As a functional magnetic resonance imaging (fMRI) technique, arterial spin labeling (ASL) can mark the cerebral blood of VCI patients at various stages without relying on the blood-brain barrier by marking the hydrogen protons in arterial blood with specific pulses. Flow rate with good time resolution has become an important imaging tool for diagnosis and follow-up of VCI. This paper reviews the basic principles of ASL technology and the research progress in VCI in recent years.]]></description>
<pubDate>Mon,20 May 2019 00:00:00  GMT</pubDate>
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<title><![CDATA[Application of amplitude of low-frequency fluctuation in ocular disease]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2019.05.017</link>
<description><![CDATA[Amplitude of low-frequency fluctuation (ALFF) is a resting state functional magnetic resonance imaging (rs-fMRI) analysis technique, which is used to measure spontaneous fluctuations of blood oxygen level-dependent functional magnetic resonance imaging (BOLD-fMRI) signal intensity in neural activity, and the signal reflects the intensity of local spontaneous brain activity at rest. The rs-fMRI technique based on the ALFF has been used more and more widely in the study of many ocular diseases, it opens up a new understanding for the study of the relationship between the characteristics of ophthalmic diseases and the changes of local brain functional areas. Now, the application of the rs-fMRI technique based on ALFF in ophthalmic diseases is summarized as follows.]]></description>
<pubDate>Mon,20 May 2019 00:00:00  GMT</pubDate>
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