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<title>Chinese Journal of Magnetic Resonance Imaging RSS feed</title>
<link>http://med-sci.cn/cgzcx/en/contents_list.asp?issue=201706</link>
<language>zh-cn</language>
<copyright>An RSS feed for Chinese Journal of Magnetic Resonance Imaging</copyright>
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<title><![CDATA[Resting-state functional magnetic resonance imaging study of ischemic post stroke depression]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2017.06.001</link>
<description><![CDATA[Objective: To investigate the altered functional connectivity (FC) of the default mode network (DMN) in patients with post ischemic stroke depression. Materials and Methods: Thirteen PSD patients and 13 matched normal controls were recruited and the resting-state fMRI images were acquired on a 3.0 T Siemens MRI scanner. The datasets were analyzed using SPM8 and REST. The bilateral precuneus were selected as regions of interest (ROIs), and functional connectivity was calculated and compared between PSD patients and normal controls. Results: The FCs of the DMN was altered in PSD patients compared to normal controls. The brain areas which showed decreased FCs including the bilateral inferior parietal lobule, bilateral frontal lobule and bilateral temporal lobule. However, the increased FC has not been found in the current study. Conclusion: Dysfunction of the DMN may be associated with the development of PSD.]]></description>
<pubDate>Tue,20 Jun 2017 00:00:00  GMT</pubDate>
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<title><![CDATA[A functional connectivity strengths study in temporal lobe epilepsy based on resting-state fMRI]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2017.06.002</link>
<description><![CDATA[Objective: Voxel-based whole brain functional connectivity strengths (FCS) map was used to investigate resting-state functional MRI (rs-fMRI) brain network abnormalities in patients with temporal lobe epilepsy (TLE). Materials and Methods: 30 patients with TLE and age, gender and years of education matched 27 normal controls (NC) were included to take rs-fMRI examination and behavioral assessment. The rs-fMRI data were processed and FCS maps were calculated. The differences of clinical basic data of groups, such as age, yeas of education, and the differences of neuropsychological test results were compared between the two groups by using two-sample t test. In addition, the differences in gender between the two groups were compared by Chi-squared test. General linear model was used to compare the FCS difference between TLE group and NC group. Linear correlation analysis was used to evaluate the relationship between cognitive function score between FCS values of brain regions with group differences in TLE patients. Results: Compared to NC group, TLE group had significantly decreased FCS values in brain regions including left superior temporal gyrus, right superior temporal gyrus, right superior frontal gyrus and right middle frontal gyrus (P＜0.05, FDR corrected). FCS values in the right superior frontal gyrus was correlated negatively with the Beck Depression Inventory scores (r=-0.433, P=0.024), In addition, FCS values in the left superior temporal gyrus was negatively correlated with the State-Trait Anxiety Inventory scores (r= -0.434, P=0.024). Conclusion: These findings suggest multiple brain regions of the whole brain functional connectivity strengths significantly decrease in TLE patient,which may help to further reveal the neural mechanism of temporal lobe epilepsy.]]></description>
<pubDate>Tue,20 Jun 2017 00:00:00  GMT</pubDate>
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<title><![CDATA[Viability assessment of magnetic resonance spectroscopy for the detection of minimal hepatic encephalopathy severity]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2017.06.003</link>
<description><![CDATA[Objective: To evaluate regional cerebral metabolic changes in minimal hepatic encephalopathy (MHE) patients using magnetic resonance spectroscopy (MRS) in 3.0 T scanner. Materials and Methods: This study comprised 30 cirrhotic patients with MHE, 29 cirrhotic patients without MHE and 30 healthy volunteers. Single-voxel proton MRS data in the anterior cingulate cortex (ACC) and basal ganglia were acquired using a 3.0 T scanner. The concentrations of N-acetylaspartate (NAA), myo-inositol  (MI), glutamate (Glu), glutamine (Gln) and creatine (Cr) were obtained by LC-model software. Statistical analysis was performed to evaluate the differences between the three groups. Results: There was a significant increase in Glu for the cirrhotic patients, particularly the MHE patients. There was an elevation of Gln in the cirrhotic patients, but not in all cirrhotic patients or controls. There was a significant decrease in MI for the cirrhotic patients, but no significant difference between the two cirrhosis groups. There was no significant difference in NAA between the three groups. Conclusion: MRS using a 3.0 T MR scanner could detect cerebral metabolic changes in cirrhotic patients with MHE. Glu levels were elevated in cirrhotic patients with MHE; Glu levels could be used as a sensitive indicator to evaluate the severity of MHE in patients with cirrhosis.]]></description>
<pubDate>Tue,20 Jun 2017 00:00:00  GMT</pubDate>
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<title><![CDATA[The application research of diffusion tensor imaging and magnetic resonance spectroscopic imaging in ischemic cerebral small vessel disease]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2017.06.004</link>
<description><![CDATA[Objective: To investigate the medical imaging evaluative value of diffusion tensor imaging combined with magnetic resonance spectroscopy in ischemic cerebral small vessel disease. Materials and Methods: Forty-two cases of ischemic SVD were imaged with conventional MRI, DTI and MRS. Average diffusion coefficient (DCavg) and fractional anisotropy (FA) were measured symmetrically, which in the lesion regions and the contralateral normal white matter area. Then the absolute metabolite concentrations of N-acetylaspartate (NAA), total cholines (Cho), total creatines (Cr) and myo-inositol (MI) in SVD lesion regions and the normal white matter regions around the lesions were detected, and the ratios of NAA/Cho, NAA/Cr, Cho/Cr, MI/Cr were calculated. To divide the 42 lesions of ischemic SVD into groups according to the imaging display, all the indexes above mentioned of each group were statistically analyzed. Results: The 42 lesions of ischemic SVD were divided into chronic ischemic focus group (30 cases) and chronic lacunar infarction group (12 cases). The DCavg values of SVD lesions significantly raised compared with those of the contralateral normal white matter area (P＜0.01), while the FA values of SVD lesions reduced (P＜0.01). Neither DCavg nor FA values between chronic ischemic focus group and chronic lacunar infractions group were significantly different (P＞0.05). The mean values of NAA, Cho and Cr of the SVD lesions were all less than those of the normal white matter regions around the lesions (P＜0.01), but there was no significant difference of MRS metabolic values between chronic ischemic focus group and chronic lacunar infarctions group (P＞0.05). Pearson correlation analysis showed that there was a negative correlation between DCavg value and FA (r=-0.383, P=0.012) in normal white matter, the FA value was positively correlated with NAA/Cho (r=0.420, P=0.006), NAA/Cr (r=0.382, P=0.012), but there was no correlation in the SVD lesions. The DCavg value was actively associated with hypertension in SVD lesions by Spearman correlation analysis (r=0.338, P=0.029). Conclusion: For the ischemic SVD, the values of DCavg, FA, NAA, Cho and Cr can reflect the micro variations and the functional damages of nerve neurolemma. Combined application of DTI and MRS could have a great contribution to clinical diagnose and pathological mechanism in ischemic SVD.]]></description>
<pubDate>Tue,20 Jun 2017 00:00:00  GMT</pubDate>
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<title><![CDATA[A preliminary study on evaluation of brain damage in acute phase of carbon monoxide intoxication with diffusion kurtosis imaging]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2017.06.005</link>
<description><![CDATA[Objective: To explore the clinical value of MR diffusion kurtosis imaging (DKI) about diagnosing micro-changes of brain tissue in acute phase of CO intoxication. Materials and Methods: Routine MRI and DKI was performed in 26 cases with CO poisoning of acute stage (case group) and 18 healthy volunteers (control group). Analyze the relationships between DWI results and clinical factors. The study group was divided into two groups baesd on whether there had lesions detected in DWI images: positive and negative group. The DKI parameters of same brain area were compared separately between two case groups and control group. Analyze the correlation between ADC and two kinds of parameters of MD and MK in these differential parts of brain of case groups respectively if there were both differences in some areas. Results: ①The positive DWI scan results were affected by a long duration of disturbance of consciousness and a diminution of GCS score; ②Compared with the controls, in case groups there was a significantly reduced MD value of bilateral globus pallidus, centrum semiovale and periventricular white matter, corpus callosum genu, and MK values were increased in bilateral globus pallidus, thalamus, centrum semiovale and periventricular white matter. Thereinto, in positive and negative group, MD values of globus pallidus were significantly reduced while MK values were  increased, and MK values of thalamus were also increased. Besides, in positive group FA values of globus pallidus were reduced; ③The results indicated that there was a strong correlation between MD or MK and ADC in case groups. The above differences were statistically significant (P＜0.05). Conclusion: DKI techniques can reflect tiny structural changes of brain tissue in acute phase of CO intoxication, which will contribute to explaining features of brain damage from a micro level.]]></description>
<pubDate>Tue,20 Jun 2017 00:00:00  GMT</pubDate>
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<title><![CDATA[Preliminary study on myocardial strain in patients with hypertrophic cardiomyopathy by MR feature tracking]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2017.06.006</link>
<description><![CDATA[Objective: The feature tracking technique of cardiac magnetic resonance (CMR-FT) was used to analyze the cardiac function and myocardial segmental strain in patients with hypertrophic cardiomyopathy (HCM), and to explore the feasibility of CMR-FT in the detection of early deformation abnormalities in patients with hypertrophic cardiomyopathy. Materials and Methods: 17 hypertrophic cardiomyopathy patients and 14 healthy subjects as control cases were enrolled in our study. CMR was performed on 3.0 T scanner with the sequence of cine steady-state free precession. Cardiac functional segmental strain (38 segments of HCM and 38 segments of healthy subjects) was measured using CVI software. Results: Left ventricular function parameters (left ventricular end-diastolic volume, left ventricular end-systolic volume and left ventricular ejection fraction) had no difference between HCM patients and healthy subjects (all P＞0.05). Segmental strain were significantly lower in patients with HCM compared to healthy subjects (all P＜0.05): circumferential strain[(-5.26±2.70)% vs (-11.68±2.06)%], long-axis strain [(-7.92±5.07)% vs (-13.93±3.89)%] and peak systolic circumferential strain[(-10.44±5.46)% vs (-18.43±2.99)%], peak systolic longitudinal strain[(-12.29±8.17)% vs (-20.26±2.93)%]. Conclusion: For hypertrophic cardiomyopathy patients with normal cardiac function, CMR-FT can detect changes of strain in hypertrophic myocardial segment in early stage, CMR-FT is able to find myocardial systolic dysfunction earlier than left ventricular function parameters.]]></description>
<pubDate>Tue,20 Jun 2017 00:00:00  GMT</pubDate>
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<title><![CDATA[The significance of MRI enhanced scan in the spinal tuberculosis]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2017.06.007</link>
<description><![CDATA[Objective: To improve the diagnosis of spinal tuberculosis by analyzing the MRI imaging findings of spinal tuberculosis. Materials and Methods: MRI imaging data of 57 patients with spinal tuberculosis confirmed by biopsy and surgery and pathology were analyzed retrospectively. The findings of MRI plain scan and enhanced scan images of spinal tuberculosis were analyzed. Results: Fifty-seven cases of cervical tuberculosis in 5 cases, 12 cases of thoracic tuberculosis, 24 cases of lumbar spine tuberculosis. Cervical vertebrae complicating thoracic vertebrae were 3 cases. Thoracic vertebrae complicating lumbar were 8 cases. Lumbar complicating sacral vertebrae were 5 cases. Only one vertebrae was involved in 2 cases, two vertebraes were involved in 41 cases, more than three vertebraes were involved in 14 cases. There were stenosis or disappearance of intervertebral space in 43 cases and 40 cases had cold abscess. There were obviously enhanced in 41 cases and weak or no enhanced in 16 cases by MR enhanced scan. 57 patients were treated with 1-3 months by the combination of multiple anti-tuberculosis chemotherapy. MR scan was performed more than 2 times in 15 patients before operation. 12 patients' imaging performances were better than that of anti-tuberculosis chemotherapy and 3 cases were not. Conclusion: MRI enhanced scan has important application value in diagnosis and treatment of spinal tuberculosis.]]></description>
<pubDate>Tue,20 Jun 2017 00:00:00  GMT</pubDate>
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<title><![CDATA[Sacroiliac joint MRI findings in SAPHO syndrome]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2017.06.008</link>
<description><![CDATA[Objective: To retrospectively evaluate the MRI features of sacroiliac joint (SIJ) disorders in 13 SAPHO patients, thus increasing the awareness of SAPHO syndrome among clinicians and improving its diagnostic accuracy. Materials and Methods: 13 SAPHO patients with SIJ involvement (female: male, 9:4; mean±SD age, 45.9±8.9 years) who presented to Peking Union Medical College Hospital between November 2014 and August 2015 were enrolled. MR images of the SIJs were evaluated. Results: In our study, 11 SAPHO patients were involved with SIJ disorders bilaterally and 2 unilaterally. Therefore, a total of 24 SIJs were affected. Among the involved 24 SIJs, lesions in 16 SIJs predominantly affected the sacrum, and lesions in 20 SIJs involved both the synovial proportion and ligamentous proportion. Several abnormal MRI signal intensities in the bone adjacent to SIJs were detected, including bone marrow edema(16/24), fatty deposition(24/24), bony erosion(18/24) and sclerosis (19/24). Joint space widening was present in 8.3%(2/24) of SIJs, joint space narrowing in 16.7%(4/24) and articular ankylosis in 20.8%(5/24). Articular effusions were observed in 25%(6/24) of SIJs. Edema in the surrounding soft tissue was detected in 8.3%(2/24) of SIJs. Conclusion: SIJs were more bilaterally involved in SAPHO patients, with predilection on the sacrum. Active lesions and chronic lesions usually coexist, with a lower prevalence of ankylosing. These MRI features could provide certain information of SAPHO syndrome. Consultation of skin lesions should be taken into consideration for a comprehensive evaluation and definite diagnosis.]]></description>
<pubDate>Tue,20 Jun 2017 00:00:00  GMT</pubDate>
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<title><![CDATA[A DTI study of brain white matter fibers in mobile phone addic of college students]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2017.06.009</link>
<description><![CDATA[Objective: To investigate the differences of brain white matter fibers between mobile phone dependent patients and control subjects by a diffusion tensor imagine (DTI) method, and explore the characteristics of changed brain white matter microstructure in mobile phone dependent patients. Materials and Methods: 25 mobile phone dependent patients and 23 control subjects were recruited, they are  from Guangzhou University of Chinese Medicine Shenzhen innovation class. The Siemens 3.0 T trio MRI was used for DTI data acquisition, voxel-based analysis, (VBA) was used for fractional anisotropy (FA) comparison between addiction group and control group, using two sample t test to analyze the differences between the two groups, and performed Alphasim correction in order to take the number of voxels larger than 26, the difference was statistically significant P＜0.005 pixels after adjusted. Using two sample t test in SPSS 13.0 software to process demographic data. Results: Compared with the control group, significant reduced FA values were found in several white matter regions including superior frontal gyrus, orbital frontal cortex, insula, ventral tegmental area, hippocampus, thalamus, cerebellum in addiction group (P＜0.005) , There were no regions showed significant increase (P＜0.005). Conclusion: Altered white matter microstructures were found in mobile phone addiction group, mainly locating in the area associated with reward circuits, control and ability to execute related brain areas.]]></description>
<pubDate>Tue,20 Jun 2017 00:00:00  GMT</pubDate>
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<title><![CDATA[Variation analysis of diffusion weighted imaging in normal brain tissue between two b and multi-b value sequence]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2017.06.010</link>
<description><![CDATA[Objective: To observe the variation of two b and multi-b diffusion weighted imaging (DWI) in normal brain tissue. Materials and Methods: Apply two b and multi-b DWI sequence to 29 normal appearance brain using GE 3.0 T scanner. Two b and multi-b DWI related parameter including apparent diffusion coefficient (ADC), true diffusion (D), perfusion related diffusion (D*), fraction of perfusion (f) was acquired using AW workstation. The coefficient of variation (CV) of these parameters was compared to evaluate the reliability. Results: The values of CV of ADC, D, D* and f of brain were (81.11±7.62)×10-5 mm/s, 0.094; (78.47±6.72)×10-5 mm/s, 0.086; (722.7±189.3)×10-5 mm/s, 0.262; (8.97±3.63)%, 0.404 in white matter; and (87.03±9.97)×10-5 mm/s, 0.115; (81.83±7.51)×10-5 mm/s, 0.092; (611.9±169.5)×10-5 mm/s, 0.292; (9.55±3.41)%, 0.357 in gray matter; and (76.70±7.17)×10-5 mm/s, 0.093; (73.72±6.40)×10-5 mm/s, 0.087; (1221.9±743.4)×10-5 mm/s, 0.608; (9.72±3.68%), 0.379 in basal ganglia respectively. The CVs of ADC and D were similar and good and lower than others. Conclusion: D which derived from Multi-b DWI has good reliability as ADC which derived from two b DWI in normal brain. Otherwise, D* and f have higher variation in normal brains, and with which the comparison between individual should be explained with caution.]]></description>
<pubDate>Tue,20 Jun 2017 00:00:00  GMT</pubDate>
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<title><![CDATA[Quantitative metabolites of lumbar intervertebral disc degeneration by diffusion tensor MR]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2017.06.011</link>
<description><![CDATA[Objective: To investigate the MR diffusion tensor imaging (DTI) as an application of quantitative analysis methods in lumbar intervertebral disc degeneration and the effects of different diffusion gradient directions (DGD) of DTI. Materials and Methods: Selected 50 patients with pain of waist or legs, including 32 male and 18 female, from 24 to 62 years old with mean age 46.9±16.2 years old, all the patients underwent sagittal scans for regular lumbar MRI and DTI, and with 6, 12, 20 DGD of DTI. According to the DGD, lumbar intervertebral discs can be divided into DD6, DD12, DD20 groups and divided lumbar intervertebral discs into Ⅱ, Ⅲ, Ⅳ, and Ⅴ groups by Pfirrmann grading system. ADC and FA and λ1 valuse were measured and analyzed among the different DGD groups and Pm groups. Results: There were no statistical difference of ADC values among the different DGD groups (P＞0.05), while statistical difference of FA and λ1 values were found (P＜0.05); DGD for 6, FA values were statistical differences among the different Pm groups (P＜0.05), except Ⅳ and Ⅴ(P＞0.05); DGD for 12 and 20, there were no statistical difference of FA values in all PM groups (P＞0.05), except Ⅱ. DGD for 6, 12, 20, ADC values were statistical difference in all Pm groups, except Ⅱ and Ⅲ. In DGD for 6, 12, 20, λ1 values had no statistical difference in all Pm groups (P＞0.05). Conclusion: DTI can be applied to the quantitative analysis of lumbar intervertebral disc, DGD for 6 can get high quality images and data in a relatively short time, and FA value can be used for quantitative analysis of different Pm grading lumbar intervertebral disc.]]></description>
<pubDate>Tue,20 Jun 2017 00:00:00  GMT</pubDate>
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<title><![CDATA[Application of multimodal magnetic resonance imaging in the diagnosis of glioma cell proliferation]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2017.06.015</link>
<description><![CDATA[Brain glioma is a kind of malignant tumor with high incidence and poor prognosis, which lacks effective method of preoperative diagnosis, grading and prognosis evaluation. Multimodal magnetic resonance imaging is able to evaluate histopathological change of tumor based on structural MRI. Cell proliferation is key to tumor development, which is closely related to the clinical diagnosis, grading, treatment and prognosis. This article will review and discuss the progresses of multimodal magnetic resonance imaging in the evaluation of brain glioma cell proliferation.]]></description>
<pubDate>Tue,20 Jun 2017 00:00:00  GMT</pubDate>
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<title><![CDATA[MRI evaluation of hepatic iron overload: recent advances]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2017.06.016</link>
<description><![CDATA[Iron overload can be caused by hereditary hemochromatosis, hematological diseases, chronic liver disease and so on. Severe iron overload can result in liver, heart, pancreas, thyroid organs, the central nervous system, and other organ dysfunction, or even can cause death. Iron overload can result in liver damage firstly, and the liver iron concentration bring into correspondence with the body iron content. MRI can accurately noninvasive assess and monitor the liver iron concentration, provide guidance for clinical treatment. This article mainly introduces MRI-based methods for quantification of liver iron, including remaining challenges, unsolved problems and potential application prospect.]]></description>
<pubDate>Tue,20 Jun 2017 00:00:00  GMT</pubDate>
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