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<title>Chinese Journal of Magnetic Resonance Imaging RSS feed</title>
<link>http://med-sci.cn/cgzcx/en/contents_list.asp?issue=202006</link>
<language>zh-cn</language>
<copyright>An RSS feed for Chinese Journal of Magnetic Resonance Imaging</copyright>
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<title><![CDATA[Evaluation of the relationship between pituitary macroadenomas and cranial nerves in the cavernous]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2020.06.001</link>
<description><![CDATA[Objective: To evaluate the relationship between pituitary macroadenomas and cranial nerves in the cavernous sinuses by contrast-enhanced three-dimensional fast imaging employing steady-state acquisition with phase cycling (CE 3D-FIESTA-C). Materials and Methods: Forty patients with pituitary macroadenomas were prospectively collected, all of whom scanned the CE 3D-FIESTA-C and contrast-enhanced brain volume (CE BRAVO) sequence, and the display rate of cranial nerves in bilateral cavernous sinus was calculated for each patient. Results: On CE 3D-FIESTA-C sequence, the display rate of cranial nerves in the cavernous sinuses was 75.0%, 25.0%, 71.3%, 71.3%, 41.3%, respectively, which was higher than CE BRAVO sequence (P＜0.01). On the CE 3D-FIESTA-C sequence, the cranial nerves at the tumor site was interrupted or not shown due to the influence of the tumor to determine the invasion of the ipsilateral cavernous sinus, and the sensitivity and specificity of diagnosis were 41.7% and 95.8%, respectively. Conclusions: The CE 3D-FIESTA-C sequence can better display the cranial nerves in the cavernous sinuses in patients with pituitary adenoma. By observing whether the cranial nerve in the cavernous sinuses is interrupted or not displayed due to the influence of tumor, it can assist the diagnosis of whether the ipsilateral cavernous sinus is invaded.]]></description>
<pubDate>Sat,20 Jun 2020 00:00:00  GMT</pubDate>
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<title><![CDATA[Correlation between MMSE and amido proton transfer, susceptibility-weighted imaging in Alzheimer<sup><sup>,</sup></sup>s disease]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2020.06.002</link>
<description><![CDATA[Objective: To evaluate the correlation between the phase values of magnetic resonance amido proton transfer (APT) imaging, magnetic sensitivity weighted imaging (SWI) and the scores of neuropsychological scale in patients with Alzheimer's disease (AD). Materials and Methods: Twenty AD patients and 20 age and gender matched normal controls were selected for routine skull sequence, SWI and APT imaging. The asymmetric magnetization transfer ratio (MTRasym) and phase value of amide protons (at 3.5 ppm) in the region of interest were measured by selecting bilateral hippocampus, amygdala and substantia nigra on the APT image and SWI phase map of the transection position. All subjects were assessed with mini mental state examination (MMSE). The difference of MTRasym (3.5 ppm) and phase value between normal control group and AD group was compared. Pearson correlation was used to analyze the correlation between the value of MTRasym (3.5 ppm), phase value and MMSE score. Results: the MTRasym (3.5 ppm) value of bilateral hippocampus in AD group was significantly higher than that in normal control group [right side: (1.39±0.17)% and (0.88±0.29)%, t=4.444, P=0.000; left side: (1.42±0.31)% and (0.91±0.36)%, t=3.867, P=0.000]. The phase value of bilateral hippocampus and substantia nigra in AD group was lower than that in normal control group (P＜0.05). The MTRasym (3.5ppm) value of bilateral hippocampus was negatively correlated with MMSE score (r= -0.618 on the right, P=0.004; r=-0.513 on the left, P=0.021), and the phase value of bilateral hippocampus (r=0.446 on the right, P=0.049; r=0.518 on the left, P=0.019 and substantia nigra (r=0.593 on the right, P=0.006; r=0.898 on the left, P=0.000) was positively correlated with MMSE score. Conclusions: APT and SWI imaging can detect the protein content and iron content in hippocampus and substantia nigra of AD patients sensitively, which is helpful for AD diagnosis.]]></description>
<pubDate>Sat,20 Jun 2020 00:00:00  GMT</pubDate>
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<title><![CDATA[Resting state functional magnetic resonance imaging studies of the brain structure and function for long-term compassion meditators]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2020.06.003</link>
<description><![CDATA[Objective: To explore the changes in brain structure and function of long-term compassion meditators. Materials and Methods: The experiment number comes from 15 long-term compassion meditators who at least have 3 years of meditation experence, and 16 non-long-term meditation male volunteers, they have the same age, gender and meditation years. Brain structural and functional sequences images were collected from all participants on a Prisma 3.0 T MR scanner, voxel-based morphology (VBM), regional homogeneity (ReHo) methods were utilized to compare the difference of gray matter volume and ReHo value between two groups. Results: Comparing the results with the normal group, the volume of gray matter from the long-term compassion meditators group increased in bilateral superior temporal gyrus, right middle occipital gyrus, left anterior central gyrus and right upper central posterior gyrus. The brain regions with increased ReHo were Left and Right thalamus and left cerebellum 4/5 area. Brain regions with decreased ReHo were Right inferior frontal gyrus, right triangle inferior frontal gyrus, right middle frontal gyrus. Conclusions: The gray matter volume of long-term compassion meditators has increased, and the ReHo value in multiple brain areas has changed. The differences of brain structure and function between the long-term compassion meditators and the normal group will provide evidence for the clinical diseases assisted by meditation in some extent.]]></description>
<pubDate>Sat,20 Jun 2020 00:00:00  GMT</pubDate>
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<title><![CDATA[The study of T1 and T2 values in differentiating of benign and malignant gliomas]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2020.06.004</link>
<description><![CDATA[Objective: To discuss the value in the classification of cerebral gliomas using magnetic resonance image complication (Magic). Materials and Methods: Twenty-two cases with gliomas confirmed by clinical surgery pathology (13 cases of high grade, 9 cases of low grade) were included. All cases were performed with Magic technology before and after enhancement; T1 values (qT1) and T2 values (qT2) within the tumor parenchyma, and peritumoral region (within 1cm around the tumor parenchyma) were measured using automatically generated T1maping and T2 maping images. Receiver operating characteristic analysis (ROC) of T1 value after enhancement and the percentage change of T1 value were performed to evaluate cut-off values between high and low-grade tumors. The sensitivity and specificity were analyzed between high-grade glioma tumor (HGG) and low-grade gliomas (LGG) with independent sample t-test. Results: The pre-contrast T1 and T2 value of the HGG parenchyma were: 1478.59±232.92, and 127.41±20.02, and T1 value after enhancement was 688.44±143.79; The percentage change of T1 value was (127±68)%; The pre-contrast T1 and T2 value of the LGG parenchyma were 1610.78±333.87, 167.15±61.09, and T1 value after enhancement was 1189.37±592.37; The percentage change of T1 value was (58±63)%. The post-contrast qT1 of HGG parenchyma was less than that of LGG parenchyma, and the percentage change of T1 value of HGG parenchyma was greater than that of LGG parenchyma significantly (P＜0.05); there were no significant differences in other measured values between the two groups. the pre-contrast T1 and T2 value of the HGG peritumoral region HGG were 1367.36±213.64 and 162.87±35.56, and T1 value after enhancement was 1334.67±260.85; the percentage change of T1 value was (4±10)%. The pre-contrast T1 and T2 value of the LGG peritumoral region were: 1239.00±259.46 and 133.07±48.07, and T1 value after enhancement was 1160.48±286.44; the percentage change of T1 value was (8±9)%. There was no statistical difference between all measured values of peritumoral regions between the HGG and LGG groups (P＞0.05). The area under the ROC curve (AUC) of qT1 after enhancement was=0.786, and the diagnostic threshold was 927 ms; the sensitivity was 55.6%, and the specificity was 100%. The AUC of the rate of the percentage change of T1 value was 0.786, and the diagnostic threshold was 42.5%; the sensitivity was 92.3%, and the specificity was 55.6%. Conclusions: The Magic scan sequence may assist in the grading of cerebral gliomas.]]></description>
<pubDate>Sat,20 Jun 2020 00:00:00  GMT</pubDate>
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<title><![CDATA[Study on diffusion tensor imaging before and after minimally invasive surgery for lumbar disc herniation]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2020.06.005</link>
<description><![CDATA[Objective: To estimate the application value of diffusion tensor imaging (DTI) technology on detecting the preoperative and postoperative microstructural changes of compressed nerve roots in patients with lumbar disc herniation. And to investigate the DTI obtained data correlation with clinical symptoms. Materials and Methods: 50 patients with unilateral nerve root compression of lumbar disc herniation confirmed by clinical diagnosis and surgery were selected for this study. All patients underwent conventional magnetic resonance imaging sequence, diffusion tensor imaging (DTI) scan, oswestry disability index (ODI) score judgement, and visual analogue scale (VAS) score judgement before surgery and 3 months after surgery. The differences in apparent diffusion coefficient (ADC), fractional anisotropy (FA), ODI score and VAS score were compared. The correlation of DTI parameters with ODI score and with VAS score was analyzed. Results: There was no significant difference in ADC values between the affected nerve roots and the healthy side before surgery (P＞0.05). The FA values of the affected nerve roots before surgery were significantly lower than that of the healthy side (P＜0.05). The FA values of the affected nerve roots were increased after operation, yet there was no significant difference when it was compared with the healthy side (P＞0.05). The preoperative FA value of the affected nerve root was negatively correlated with the preoperative ODI score (r=-0.494, P＜0.05) and VAS score (r=-0.560, P＜0.05). The FA value of the affected nerve root before surgery was positively correlated with the improvement of ODI score (r=0.492, P＜0.05) and VAS score (r=0.435, P＜0.05). Conclusions: DTI could be quantitatively used to evaluate the microstructural changes of the compressed nerve roots, and it also provides reference values for the selection of patients' treatments and accurate assessment of postoperative curative effect.]]></description>
<pubDate>Sat,20 Jun 2020 00:00:00  GMT</pubDate>
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<title><![CDATA[Evaluation of skeletal muscle microvascular permeability and texture analysis based on DCE-MRI in diabetic mellitus merged with critical limb ischemia rabbits]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2020.06.006</link>
<description><![CDATA[Objective: To evaluate skeletal muscle microvascular permeability and blood perfusion in diabetic rabbits with critical limb ischemia by using permeability and texture analysis based on quantitative dynamic contrast enhanced magnetic resonance imaging (DCE-MRI). Materials and Methods: Japanese big ear rabbits were randomly assigned to experimental (n=12) and sham-operated (n=12) group. After modeling, all rabbits underwent axial MR imaging (DCE-MRI) of the vastus lateralis muscle at fixed time points (1, 2, 3 weeks after operation). The pharmacokinetic model was used to acquire the quantitative permeability parameters of DCE-MRI and texture analysis based on Ktrans. Independent sample t test or Mann-Whitney U test and repeated measures analysis was used to compare the difference of permeability parameters between experimental and sham-operated group at the same time point. The texture features extracted in both group at week 3 were modeled for further feature screening. The area under the curve (AUC) was obtained by joint ROC curve analysis of the texture parameters with statistical differences. The correlation of permeability parameters and texture parameters with MVD (CD31) and peripheral blood EPCs was analyzed. Results: The difference of vastus lateralis muscle of Ktrans value at each time point in the experimental group was statistically significant, Texture analysis based on DCE-MRI were significantly different in both group. The AUC value is 0.882, there was a correlation between pathological and texture parameters. Conclusions: Permeability parameters and texture analysis based on DCE-MRI quantitative can be used to evaluate microvascular permeability and blood perfusion of diabetic mellitus merged with critical limb ischemia rabbits skeletal muscle.]]></description>
<pubDate>Sat,20 Jun 2020 00:00:00  GMT</pubDate>
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<title><![CDATA[Diffusion weighted imaging of head based on GRADE-DWI sequence]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2020.06.007</link>
<description><![CDATA[Objective: To compare brain image quality between echo-planar imaging diffusion-weighted imaging (EPI-DWI) and gradient and spin echo diffusion-weighted imaging (GRASE-DWI) in magnetic resonance imaging (MRI) examination of head. Materials and Methods: This prospective study enrolled patients with clinical suspicion of cerebral infarction. The scans were performed on a 3.0 T MRI with sequences consisted of T2W-TSE, T1W-TSE, single-shot EPI-DWI and GRASE-DWI. Two blinded neuroradiologists evaluated both EPI-DWI and GRASE-DWI images independently using a 5-point Likert scale. The evaluation included image definition, distortion and magnetic susceptibility artifact. For patients confirmed with cerebral infarction diagnosis, apparent diffusion coefficient (ADC) value, misaligned distance of fusion images of TIWI-TSE and two DWIs, signal-to-noise ratio (SNR), signal intensity ratio (SIR), and contrast-to-noise ratio (CNR) were also obtained for further comparisons. Interobserver agreement was also evaluated. Results: 45 patients were included in this study. Among them, 33 patients were diagnosed with cerebral infarction. The distortions and magnetic susceptibility artifacts of GRASE-DWI were smaller than those of EPI-DWI (P＜0.05). There was no significant difference in the image definition between groups (P＞0.05), and the interobserver agreement was good (Kappa=0.67, 0.61, 0.69, 0.71). The SNR and CNR of GRASE-DWI were lower than those of EPI-DWI (P＜0.05), there was no significant difference in the SIR (P=0.08). ADC values of GRASE-DWI, in both normal brain tissues and infarcted areas, were higher than those of EPI-DWI (P＜0.05). Misaligned distance between GRASE-DWI and EPI-DWI showed significant differences (P＜0.05). Conclusions: GRASE-DWI could significantly improve DWI image quality by reducing the susceptibility artifacts and distortions.]]></description>
<pubDate>Sat,20 Jun 2020 00:00:00  GMT</pubDate>
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<title><![CDATA[Analysis of MRI-related adverse event reports]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2020.06.008</link>
<description><![CDATA[Objective: To analyze the types and causes of adverse events and recall data through MRI 10-years adverse events in US combined with active recall data in China. Materials and Methods: Based on SUS database, collected 1548 MRI instruments, MRI dedicated coils, MR spectroscopy imaging and PET/MRI adverse events from January 1, 2008 to December 31, 2017; Based on the website of National Medical Products Administration, included 30 MRI, PET/MRI incidents reported to China from January 1, 2011 to December 31, 2019. Results: The type and number of MRI adverse events of fruit 1548 were 906(58.5%) of overheating injury, 170(11.0%) of mechanical damage, 133(8.6%) of ferromagnetic projection damage, 109(7.0%) of confounding events, 89(5.7%) of image quality, 86(5.6%) of noise, 55(43.6%) of unknown cause, 0(0%) of peripheral nerve stimulation; the type and number of MRI overheating injury-adverse events of fruit 906 were 348(38.4%) of unknown cause, 257(28.4%) of contact with a conductive object, 147(16.2%) of skin-to-skin contact, 97(10.7%)of bore contact, 57(6.3%) of not RF related events; the types and number of active MRI recall events in China were helium leakage 7(23.3%), overheating damage 6(20.0%), image quality 6(20.0%), mechanical damage 5(16.7%), magnet loss 3(10.0%), label 3(10.0%). Conclusions: The types and causes of adverse events and recall data are of great value to China manufacturers, clinical institutions and regulators in controlling MRI-related risks.]]></description>
<pubDate>Sat,20 Jun 2020 00:00:00  GMT</pubDate>
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<title><![CDATA[Research progress of the interhemispheric structural and functional connections after stroke]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2020.06.014</link>
<description><![CDATA[The network of bilateral cerebral hemispheres is coordinated and integrated through interhemispheric structural and functional connections. After the stroke, the interhemispheric structural and functional connections undergo extensive changes. These changes are closely related to neurological function deficit after stroke and its subsequent recovery. The evaluation of the changes in the interhemispheric structural and functional connections may be helpful in monitoring the recovery of neurological function. Regulating interhemispheric functional connectivity to promote the recovery of neurological function after stroke is also a new rehabilitation method that is currently being explored. Diffusion tensor imaging (DTI) and resting state functional magnetic resonance imaging (rs-fMRI) are commonly used to evaluate structural and functional connectivity. In this review, the authors briefly introduce the background of each method and review the current research progress in evaluating the changes in the interhemispheric structure and functional connections after stroke using DTI and rs-fMRI.]]></description>
<pubDate>Sat,20 Jun 2020 00:00:00  GMT</pubDate>
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<title><![CDATA[Research progress of MR vessel wall imaging of responsible blood vessels of ischemic stroke]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2020.06.015</link>
<description><![CDATA[Previous studies have suggested that the responsible vessels for ischemic stroke are the narrow vessels corresponding to the infarcted area, especially when intracranial vessel stenosis＞50% may cause a stroke. However, more and more studies have found that patients with stroke without obvious stenosis on the MRA have found corresponding atherosclerotic plaques on the MR wall imaging of the intracranial artery. Therefore, we believe that the vulnerability of plaque may be the main cause of ischemic stroke. MR wall imaging of intracranial arteries can clearly show the wall conditions of intracranial vessels. Therefore, this article reviews the characteristics of the vessel wall of the responsible vessels in ischemic stroke and how to quantify the vulnerable plaques in the responsible vessels.]]></description>
<pubDate>Sat,20 Jun 2020 00:00:00  GMT</pubDate>
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<title><![CDATA[The progress of functional magnetic resonance imaging and Ki-67 labeling index in the assessment of malignancy in gliomas]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2020.06.016</link>
<description><![CDATA[Brain gliomas are the most common intracranial malignant tumor, the higher the degree of malignancy, the higher the grade, the worse the prognosis. The assessment of brain gliomas malignancy is important to predict tumor grade, tumor behavior and prognosis. Ki-67 is a protein reflecting cellular proliferation and malignancy; higher Ki-67 labeling index correspond to higher proliferation and greater malignancy. However, the assessment of Ki-67 labeling index requires biopsy or surgical removal, a noninvasive method to predict Ki-67 labeling index would be of great importance for the assessment of proliferative potential and malignancy of brain glioma. Using noninvasive magnetic resonance imaging techniques to predict the Ki-67 labeling index is indispensable for the assessment of tumor malignancy. In the paper, we review the contribution of functional magnetic resonance and Ki-67 labeling index for the assessment of the gliomas malignancy.]]></description>
<pubDate>Sat,20 Jun 2020 00:00:00  GMT</pubDate>
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<title><![CDATA[The research progress of amide proton transfer weighted imaging in neurodegenerative disease]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2020.06.017</link>
<description><![CDATA[Neurodegenerative disease is a kind of disease with progressive neuronal degeneration and death, which leads to chronic progressive neurological dysfunction, including Alzheimer's disease, Parkinson's disease, multiple sclerosis and traumatic brain injury. In recent years, the incidence of neurodegenerative diseases has increased year by year, which has a serious impact on patients' daily work, study and life. Amide proton transfer imaging is a relatively new magnetic resonance imaging technique developed in recent years, which indirectly reflects the metabolic changes and physiological and pathological information in living cells by detecting endogenous free proteins and polypeptide molecules. The purpose of this paper is to explain the technical principle of APT and summarize its research status in neurodegenerative related diseases.]]></description>
<pubDate>Sat,20 Jun 2020 00:00:00  GMT</pubDate>
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<title><![CDATA[Cardiac magnetic resonance feature tracking technique and its progress]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2020.06.018</link>
<description><![CDATA[Cardiac magnetic resonance feature tracking (CMR-FT), a new emerged myocardial strain technique based on conventional MRI cine sequences, takes advantages in easy post-processing, high spatial resolution images and no demand for additional special sequences. Hence, it is widely used in atrial and ventricular myocardial strain measurement, playing a guiding role in the diagnosis and prognosis of variable cardiovascular diseases. This review aimed to summarize the principles and clinical application of CMR-FT and its up-to-date progress.]]></description>
<pubDate>Sat,20 Jun 2020 00:00:00  GMT</pubDate>
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<title><![CDATA[Research progress in the diagnosis and treatment of tumors by magnetic iron oxide nanoparticles with chemotherapeutics]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2020.06.019</link>
<description><![CDATA[Magnetic oxygen nanoparticles (NPs) have attracted wide attention due to their unique properties. NPs can be combined with fluorescent probes, biological targeting molecules or anti-tumor drugs to achieve the multifunctionality of magnetic nanoparticles, so they have good application prospects in multimodal imaging, targeted diagnosis and treatment of cancer. Magnetic iron oxide nanoparticles (IONP) have the advantages of small particle size, high biological safety, and superparamagnetism. In addition to T2 weight imaging (T2WI) MR imaging, IONP also has drug loading and magnetic targeting functions. It is currently a hot research topic in cancer diagnosis and treatment. This article reviews the research on IONP imaging performance, tumor targeting, and the emphasis on carrying different types of chemotherapy drugs.]]></description>
<pubDate>Sat,20 Jun 2020 00:00:00  GMT</pubDate>
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<title><![CDATA[Application progress of radiomics in cervical cancer]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2020.06.020</link>
<description><![CDATA[The incidence and mortality of cervical cancer are high and increasing, the age of onset was significantly younger, therefore, early diagnosis and treatment become particularly important. The treatment depends on the clinical stage, and the prognosis of patients with the same clinicopathological characteristics are quite different. Radiomics can improve the diagnosis and prognosis of cervical cancer owing to its characteristics of noninvasive, quantitative, rapid, dynamic and repeatable, and help clinicians in making decisions. This paper will review the process of radiomics, the application status and development prospect of radiomics in cervical cancer.]]></description>
<pubDate>Sat,20 Jun 2020 00:00:00  GMT</pubDate>
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