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<title>Chinese Journal of Magnetic Resonance Imaging RSS feed</title>
<link>http://med-sci.cn/cgzcx/en/contents_list.asp?issue=202107</link>
<language>zh-cn</language>
<copyright>An RSS feed for Chinese Journal of Magnetic Resonance Imaging</copyright>
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<title><![CDATA[Study of brain magnetic resonance imaging in patients with hypertension and type 2 diabetes mellitus based on DKI technology]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2021.07.001</link>
<description><![CDATA[Objective: To evaluate the early subclinical brain cell damage in patients with hypertension and type 2 diabetes mellitus (T2DM) by diffusion kurtosis imaging (DKI). Materials and Methods: Twenty-six patients with hypertension and T2DM without neurological function and cognitive impairment, 27 patients with simple hypertension and 16 healthy subjects matched with gender, age and education level, were enrolled in this study, brain MRI and DKI were performed in three groups. The mean kurtosis (MK), mean diffusivity (MD) and fractional anisotropy (FA) of bilateral hippocampal gyrus, centrum semiovale, caudate head, posterior limb of internal capsule, thalamus, red nucleus, substantia nigra, pons and cerebellum were measured. Results: There were significant differences in MK values of left hippocampus gyrus, left centrum semiovale, bilateral caudate head and left posterior limb of internal capsule between three groups (P＜0.05 or P＜0.01), and there were significant differences in MK values of bilateral thalamus and left substantia nigra between some groups (P＜0.05 or P＜0.01). MD value in the right thalamus was significantly different between the three groups (P＜0.05 or P＜0.01), MD value in the right caudate head was significantly different between the some groups (P＜0.05 or P＜0.01). There was significant difference in FA value of left posterior limb of internal capsule between the three groups (P＜0.05 or P＜0.01), and there were significant difference in FA values of left centrum semiovale, right posterior limb of internal capsule between the some groups (P＜0.05 or P＜0.01). Conclusions: The brain cell of hippocampus gyrus, centrum semiovale, caudate head, posterior limb of internal capsule, thalamus and substantia nigra has been damaged in patients with hypertension and T2DM, and the damage was more serious than that in patients with simple hypertension.]]></description>
<pubDate>Tue,20 Jul 2021 00:00:00  GMT</pubDate>
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<title><![CDATA[Evaluation of left ventricular strain and its diagnostic value in dilated cardiomyopathy by cardiovascular magnetic resonance feature tracking technology]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2021.07.002</link>
<description><![CDATA[Objective: To evaluate left cardiac function, left ventricular 3D strain and the diagnostic value of strain for non-ischemic dilated cardiomyopathy (NIDCM) in patients with NIDCM based on cardiovascular magnetic resonance feature tracking technology (CMR-FT). Materials and Methods: Thirty-three patients (NIDCM group) and 33 healthy volunteers (control group) were enrolled in this study underwent CMR to compare the left ventricular function and strain parameters of the two groups. According to LGE results, the left ventricular myocardium in the NIDCM group was divided into LGE positive (164) and LGE negative (364) groups according to the 17-segment segmentation method, and the 3D strain parameters of the two groups were compared. Repeatability test, inter-group and intra-group mean comparison, Pearson correlation analysis, Logistic regression model and receiver operating characteristic (ROC) curve analysis were performed for each group. Results: The 3D global strain in NIDCM group were lower than those in control group, the differences between the two groups were significant (P＜0.001). Left ventricular ejection fraction (LVEF) in NIDCM group was significantly lower than that in control group (P＜0.001), left ventricular end diastolic volume (LVEDV), left ventricular end systolic volume (LVESV) and left ventricular mass (LVM) in the control group were higher than those in the control group (all P＜0.001). The LVEF in NIDCM group was negatively correlated with the GCS (P＜0.01). There were significant differences in RS, CS and LS between LGE positive and LGE negative segments in NIDCM group (all P＜0.05). RS of LGE positive myocardial segments had certain diagnostic value in the diagnosis of NIDCM positive myocardial segments (AUC=0.785), there was no significant diagnostic value for CS and LS (AUC=0.584, 0.665, respectively). The combined diagnosis of RS and CS had certain diagnostic value (AUC=0.789), RS and LS (AUC=0.811), CS and LS (AUC=0.712). The combined diagnostic value of RS, CS and LS (AUC=0.810) was nearly consistent with that of RS and LS. Conclusions: Strain analysis using CMR-FT has good repeatability. LVEF in NIDCM group was strongly correlated with left ventricular GCS. Strain analysis using CMR-FT technology can identify myocardial fibrosis in patients with NIDCM without contrast agent and has potential clinical value.]]></description>
<pubDate>Tue,20 Jul 2021 00:00:00  GMT</pubDate>
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<title><![CDATA[Semiquantitative and quantitative analyses of dynamic contrast-enhanced magnetic resonance imaging in the differentiation between malignant and benign thyroid nodules]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2021.07.003</link>
<description><![CDATA[Objective: To investigate the diagnostic efficacy of semiquantitative and quantitative dynamic contrast-enhanced MRI (DCE-MRI) parameters in the differentiation of malignant and benign of thyroid nodules. Materials and Methods: In this retrospective analysis, 45 patients with pathological confirmed thyroid nodule and presurgical DCE-MRI were enrolled. For each lesion, quantitative MRI kinetics including: volume transfer constant (Ktrans), rate constant (Kep), extravascular extracellular volume fraction (Ve) and semiquantitative MRI kinetic including: initial area under gadolinium concentration time curve (IAUGC), maximum slope of increase (Max Slope), contrast enhancement rate (CER), time-intensity curves (TIC) were plotted and calculated obtained. The Mann-Whitney U test and Fisher exact test was used to test the statistically significant differences of in continuous and categorical parameters between benign and malignant nodules, respectively. Then, ROC curve analysis was performed to assess the diagnostic efficiency of each parameter in differentiating benign and malignant nodule. Results: Among 45 patients, 12 benign and 34 malignant lesions were identified. No significant differences were found between malignant and benign lesions in mean Ktrans, V , and K for benign lesions were (3.63±2.83) min−1 vs. (2.70±2.42) min−1, (1.41±1.01) min−1 vs. (1.23±1.23) min−1, (0.48±0.19) min−1 vs. (0.51±0.22) min−1 respectively (all P＞0.05). However, for semiquantitative parameters, significant difference was found in CER (benign vs malignant = [(2.04±0.67) seconds vs. (1.55±0.67) seconds, P=0.04], but not in Max Slope [(0.10±0.10) seconds vs. (0.07±0.10) seconds, P=0.37] and IAUGC [(0.78±0.38) seconds vs. (0.94±0.67) seconds, P=0.45]. The optimal specificity and sensitivity for the CER were 0.75, 0.62 respectively with AUC of 0.72 most of the masses with type-Ⅱcurve were malignant (16/31) and type-Ⅲ curve were benign (10/12) with significant difference (P=0.02). Conclusions: DCE-MRI, especially the semi-qualitative TIC pattern and quantitative value of CER could be potential indicators in distinguishing malignant benign and malignant thyroid lesions. However, no significant value was shown using DCE-MRI-based quantitative parameters to differentiate benign and malignant thyroid nodules, which warrants further investigation with larger sample size data.]]></description>
<pubDate>Tue,20 Jul 2021 00:00:00  GMT</pubDate>
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<title><![CDATA[Influence of liver iron overload and steatosis on ADC value in evaluating liver fibrosis in patients with chronic hepatitis B]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2021.07.004</link>
<description><![CDATA[Objective: To investigate the effect of hepatic iron overload and steatosis on ADC value in evaluating liver fibrosis in patients with chronic hepatitis B (CHB). Materials and Methods: Seventy-three patients with CHB were included in this study. R2* and proton density fat fraction (PDFF) were measured by multi-echo Dixon for the diagnosis of hepatic iron overload and steatosis, respectively. Patients were grouped according to the presence or absence of liver iron overload and steatosis. The differences of ADC values between the groups were estimated. Liver fibrosis grading was performed according to an alternative standard recommended by WHO. The correlation between ADC values and R2*, PDFF, fibrosis grade, age, gender was analysed. Multiple linear regression analysis was performed. The correlation between ADC values and fibrosis grade was analysed after excluding patients with liver iron overload or/ and steatosis. Results: The ADC values of the liver iron overload group and the steatosis group were significantly reduced (P＜0.05). R2*, PDFF, and liver fibrosis grade were all negatively correlated with ADC values (r=-0.457, -0.298, -0.385, respectively, P＜0.05). And they were affecting factors of ADC values (standardized regression coefficient=-0.307, -0.382, -0.412; t=-2.666, -3.331, -3.510; respectively, P＜0.05). After excluding patients with liver iron overload or/and steatosis, the correlation between ADC value and liver fibrosis grade was significantly improved, and the correlation coefficients were -0.573, -0.456, and -0.688, respectively, P＜0.05. Conclusions: Hepatic iron overload and steatosis could reduce the ADC value and additionally affect the correlation between ADC values and liver fibrosis grade. When using ADC value to evaluate liver fibrosis in patients with CHB, the influence of liver iron overload and steatosis should be noticed.]]></description>
<pubDate>Tue,20 Jul 2021 00:00:00  GMT</pubDate>
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<title><![CDATA[Comparation of amide proton transfer-weighted and T2 mapping in quantifying rectal cancer with and without chemotherapy: a preliminary study]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2021.07.005</link>
<description><![CDATA[Objective: To explore the value of amide proton transfer-weighted (APTw) and T2 mapping quantitative parameters in the comparative study of chemotherapy and non-chemotherapy lesions of rectal cancer. Materials and Methods: Data from 46 patients with rectal cancer undergoing pelvic MRI at 3.0 T in our hospital were retrospectively analyzed, including 15 cases with chemotherapy (group A) and 31 cases without chemotherapy (group B). Scanning sequences included ATPw, T2 mapping and so on. Referring to the anatomical location obtained on T2 weighted imaging (T2WI), diffusion weighted imaging (DWI) and dynamic contrast enhancement MRI (DCE-MRI) images, the axial largest lesions corresponding to APTw and T2 mapping parameter images were selected, and three ROI were placed at this level, respectively, by two radiologists. The values of APTw and T2 were measured. The data were tested with inter-class correlation coefficient (ICC) to evaluate inter-observer agreement. Independent sample t-test or Mann-Whitney U was used to test the difference of APTw and T2 values between the two groups. Logistic regression was used to calculate the predicted value of APTw-T2 mapping joint parameters. The ROC curves of the parameters that were different between the two groups were evaluated respectively. Delong test was used to compare the efficacy among APTw, T2 mapping and their combined parameters. Results: The data consistency of two doctors was good (ICC＞0.75). The APTw and T2 values in group A were 1.52%±0.56% and (72.67±8.56) ms, respectively, which were both significantly lower (P＜0.05) than those in group B [APTw: 2.88% (0.77%), and T2: 86.31 (8.77) ms]. AUC of APTw and T2 values to differentiate group A and B were 0.934 and 0.923, respectively. The sensitivity, specificity and threshold value of APTw and T2 values in differentiating the two groups were 93.5%, 93.3%, 2.11% and 90.3%, 86.7%, 80.79 ms, respectively. For the predicted value of APTw-T2 mapping of the two groups, the AUC, sensitivity and specificity were 0.981, 100% and 96.8%, respectively. Delong test showed that there was no significant difference in AUC among APTw-T2 mapping, APTw and T2 mapping. Conclusions: Both APTw and T2 mapping can quantitatively distinguish rectal cancer lessions with chemotherapy from no chemotherapy.]]></description>
<pubDate>Tue,20 Jul 2021 00:00:00  GMT</pubDate>
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<title><![CDATA[An explorative resting-state fMRI study of central mechanism in patients with primary dysmenorrhea during menstrual phase by using the method of degree centrality]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2021.07.006</link>
<description><![CDATA[Objective: To investigate the central mechanism during menstrual phase in patients with primary dysmenorrhea (PDM) by using the method of degree centrality (DC) based on resting-state functional magnetic resonance imaging (rs-fMRI). Materials and Methods: Thirty-five patients (PDM group) and forty-one healthy women (HC group) were recruited for the study. The clinical data of two groups was performed, including Visual Analogue Scale for Pain and Anxiety, accompanying Symptom Score of Dysmenorrhea. Meanwhile, rs-fMRI data were collected. The difference of DC values between the two groups and the correlation between DC values in different brain regions and clinical data were analyzed by using DPABI software. Results: Compared to the healthy controls, patients with PDM demonstrated significantly increased DC values in the bilateral middle frontal gyrus, left orbital superior frontal gyrus and precuneus, and decreased values in the left brainstem, superior and middle temporal gyrus (Gaussian random field corrected, voxel P＜0.001, cluster P＜0.05, two tailed). The DC value of the right middle frontal gyrus was negatively correlated with the course of disease (r=0.383, P=0.023). Conclusions: Among the central mechanisms during menstrual phase in PDM patients, the prefrontal region may be involved in the compensatory brain activity in response to cognitive regulation of pain,, while the precuneus may be involved in the central pain sensitization mechanism. The cerebellum and brainstem may also be involved in pain-related processing.]]></description>
<pubDate>Tue,20 Jul 2021 00:00:00  GMT</pubDate>
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<title><![CDATA[The value of T2 mapping texture features of 3.0 T MRI in grading cartilage injury of knee osteoarthritis]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2021.07.007</link>
<description><![CDATA[Objective: To explore the diagnostic performance of texture analysis based on 3.0 T MRI T2 mapping in different levels of cartilage injury in knee osteoarthritis patients. Materials and Methods: Retrospective analysis of experimental group keen osteoarthritis patients (KOA) 72 knee joints and control group healthy volunteers (H) 22 knee joints. Through the sagittal T2 mapping T2 pseudocolor, to draw ROI and mark ICRS grading in a T2 artifact, a total of 201 articular surface images were selected consistent with MRI ICRS grading and arthroscopic grading, OK software was used to extract and analyze texture parameters. According to the ratio of 7∶ 3, 143 articular surface images were randomly selected as the training set, and the remaining 58 articular surface images were used as the verification set. The parameters of the training set were filtered by Spearman and sbf (select by filter), the characteristics were selected by random forest function, and the model was established by ctree to give the weight of the characteristics in the identification of normal cartilage and different cartilage injury grades. AUC, sensitivity, specificity and accuracy were used to evaluate the performance of the model in predicting normal cartilage and different cartilage injury grades. Results: MinLocation, MaxSize and Maximun3DDiameter weights are consistent, among them MinLocation was the largest weight of each damage grade, over 0.75. AUC value of normal cartilage in training set was 0.91, grade Ⅰ damage AUC 0.82, grade Ⅱ damage AUC 0.84, grade Ⅲ damage AUC 0.88; verified that the AUC value of concentrated normal cartilage was 0.87, grade Ⅰ damage AUC 0.74, grade Ⅱ damage AUC 0.84, grade Ⅲ damage AUC 0.96. AUC highest was the validation of the grade Ⅲ damage to cartilage, 0.96. The second was the training of normal cartilage, 0.91. Both in the training set and the verification set show good predictive value. The most sensitive is the injury of cartilage in training set Ⅰ, 0.83 percent. The highest specificity was the injury of cartilage in training set Ⅲ , 0.98. Conclusions: Texture parameters extracted by T2 mapping have better ability to distinguish different cartilage damage.]]></description>
<pubDate>Tue,20 Jul 2021 00:00:00  GMT</pubDate>
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<title><![CDATA[Analysis of corticospinal tract injury in stroke based on a corticospinal tract template derived from healthy subjects]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2021.07.008</link>
<description><![CDATA[Objective: To explore the relationship between diffusion parameters of corticospinal tract (CST) and motor dysfunction in stroke using diffusion tensor imaging (DTI). Materials and Methods: DTI data were collected from 37 unilateral subcortical stroke patients and 30 healthy subjects (HCs). A CST template was generated from the CST of HCs which was tracked by using the probabilistic tractography. Based on the template, the diffusion parameters of fractional anisotropy (FA) and mean diffusivity (MD) were measured , further, the FA ratio (rFA), FA asymmetry (FAasy), MD ratio (rMD) and MD asymmetry (MDasy) were calculated to assess the CST impairments in stroke patients. Furthermore, the correlations of these CST diffusion parameters with Fugl-Meyer Assessment (FMA) were performed. Results: Compared with HCs, FA of the ipsilesional CST and rFA decreased significantly (t=-15.775, t=-11.111, P＜0.001, respectively) while FAasy increased significantly (t=9.473, P＜0.001); MD of the ipsilesional CST and rMD increased significantly (t=9.553, t=7.733, P＜0.001, respectively) while MDasy decreased significantly (t=-8.941, P＜0.001); no significant differences of these diffusion parameters were observed in the contralesional CST (P＞0.05). Neither disease duration nor lesion size was significantly correlated with these diffusion parameters (P＞0.05). FA of the ipsilesional CST and rFA was positively correlated with "hand+wrist" and upper limb FMA (r=0.342, P=0.038; r=0.479, P=0.003; r=0.343, P=0.038; r=0.482, P=0.003, respectively), while FAasy was negatively correlated with "hand+wrist" and upper limb FMA (r=-0.353, P=0.032; r=-0.490, P=0.002, respectively). In addition, stepwise regression analysis revealed that the correlations between FAasy and "hand+wrist" and upper limb FMA was stronger than that with FA of the ipsilesional CST and rFA (Beta=-0.353, P=0.032; Beta=-0.490, P=0.002, respectively). Conclusions: FA parameters derived from CST template may reflect CST microstructural integrity impairments following stroke. FAasy was closely related to the "hand+wrist" and upper limb FMA implying an important reference index for assessing motor dysfunction of the upper limbs and "hand+wrist" in stroke patients.]]></description>
<pubDate>Tue,20 Jul 2021 00:00:00  GMT</pubDate>
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<title><![CDATA[Study of whole-liver histogram analysis based on Gd-EOB-DTPA hepatobiliary phase for evaluating liver fibrosis in rabbits]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2021.07.009</link>
<description><![CDATA[Objective: To explore parameters derived from whole-liver histogram analysis (HA) with Gd-EOB-DTPA enhanced MRI hepatobiliary phase in quantitatively evaluating liver fibrosis (LF). Materials and Methods: One hundred rabbits were randomly divided into CCl4-induced LF group (n=80) and control group (n=20), and then were scheduled for hepatobiliary phase imaging examination. Whole-liver region of interest was drawn, and histogram analysis metrics including minimum, maximum, mean, median, skewness, kurtosis, inhomogeneity, entropy, and nth percentiles were extracted from hepatobiliary phase. Parameters were compared among different LF stages using Mann-Whitney U test and receivers operating characteristic curve, using histopathological results as reference standard. Results: Eighty-four patients were enrolled, 18, 17, 17, 18, and 14 rabbits were pathologically diagnosed as F0—F4, respectively. HAparameters including the inhomogeneity (r=0.809), 90th (r=0.718), 75th (r=0.645), entropy (r=0.546), median (r=0.425) and kurtosis (r=0.305) of hepatobiliary phase demonstrated significant positive correlation with increasing fibrosis stage (P＜0.05). Inhomogeneity, 90th, 75th and entropy were of value in different normal (F0), early stage (F1—F2) and advanced (F3—F4) stage. The inhomogeneity parameter demonstrated higher diagnostic efficacy than other histogram analysis parameters in fibrosis staging, with an AUC value of 0.87 for F0 vs. F1—F4, 0.77 for F0 vs. F1—F2, 0.90 for F1—F2 vs. F3—F4, and 0.97 for F0 vs. F3—F4. Conclusions: Histogram analysis of Gd-EOB-DTPA enhanced MRI hepatobiliary phase provide higher diagnostic value in distinguishing LF stages, which can be served as an effective imaging alternative in staging LF.]]></description>
<pubDate>Tue,20 Jul 2021 00:00:00  GMT</pubDate>
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<title><![CDATA[Resting state functional magnetic resonance imaging of somatic symptom disorder based on fALFF and DC]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2021.07.010</link>
<description><![CDATA[Objective: Using resting-state functional magnetic resonance image (rs-fMRI) combined with fractional amplitude of low-frequency fluctation (fALFF) and degree centrality (DC) to explore the change of brain function in patients with somatic symptom disorder (SSD), so that it will provide reference information for clinical treatment. Materials and Methods: Forty five right-handed patients with somatic symptoms disorder and 43 right-handed healthy controls participated in rs-fMRI scanning. ALFF and DC analysis were used to detect the characteristics of spontaneous brain activity in SSD patients at resting-state. SPM 12 software was used to analyze fMRI data. The statistical threshold of fALFF and DC was voxel level (P＜0.001) by two sample t-test. The cluster level was corrected by family wise error (FWE), P＜0.05. When the cluster more than 10 voxels was reported. Results: Patients with SSD showed increased fALFF values in limbic lobe, and thalamus compared with HCs. Besides, atients wit SSD showed decreased DC values in frontal lobe, cingulate gyrus. Conclusions: These dysfunction areas seem to have a particular importance for the occurrence of SSD, which may result in dysfunction in emotional processing, interoception, and body perception.]]></description>
<pubDate>Tue,20 Jul 2021 00:00:00  GMT</pubDate>
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<title><![CDATA[Multiparameters of DWI and DCE-MRI in differentiation between parotid Warthin tumor and pleomorphic adenoma]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2021.07.011</link>
<description><![CDATA[Objective: To investigate the value of multiparametric features including diffusion weighted imaging and dynamic contrast-enhanced MRI in differentiation between parotid Warthin tumor and pleomorphic adenoma (PA). Materials and Methods: Forty-eight patients were included in this study including 32 parotid Warthin tumors and 24 pleomorphic adenomas. Conventional and multiparametric MRI features were analyzed. Differences in conventional MRI features, ADCs, previous signal intensity (SIpre)、maximum signal intensity of enhancement (SImax) and signal intensity of the end of enhancement (SIend), wash-out ratio (WR), time to peak (TTP), and time-intensity curves (TICs) types between the two entities were determined by χ2 test and independent samples t-test.Receiver operating characteristic (ROC) curves of parameters being statistically different between groups were drawn for differential diagnosis of Warthin tumor and PA of parotid gland, and the corresponding diagnostic efficacy were analyzed. Results: The ages of Warthin tumors were significantly older than those of pleomorphic adenomas (t=9.33, P＜0.05). The male to female ratios were significantly different between the two entities (P＜0.05). The ADCs of Warthin tumors [(0.634±0.201)×10-3 mm2/s] were significantly lower than those of pleomorphic adenomas [(1.084±0.453) ×10-3 mm2/s] (t=-5.00, P＜0.05). There were significant differences in SIpre (t=4.01, P=0.0002)、WR (t=15.10, P＜0.0001)、TTP (P＜0.05) and TIC types (P＜0.05) between the two entities. Taking ADC= 0.811×10-3 mm2/s as threshold drawing ROC for differential diagnosis of Warthin tumor and PA of parotid gland, the area under the curve (AUC), sensitivity, specificity, were 0.845 (P＜0.05), 83.3%, 90.63%. Taking TIC types drawing ROC, the AUC, sensitivity, specificity, were 0.961 (P＜0.05), 95.45%, 100%. Taking ADCs combined with TIC types drawing ROC, the AUC, sensitivity, specificity, were 0.984 (P＜0.05), 100%, 96.88%. Conclusions: Multiparameters and combined parameters of DWI and DCE-MRI were helpful to differential diagnosis of Warthin tumor and pleomorphic adenoma of parotid.]]></description>
<pubDate>Tue,20 Jul 2021 00:00:00  GMT</pubDate>
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<title><![CDATA[Multi-parameter MR scan was used to evaluate the clinical significance of T staging of renal cell carcinoma]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2021.07.012</link>
<description><![CDATA[Objective: To evaluate the accuracy of renal cell carcinoma (RCC) T staging by multi-parameter MR scan. Materials and methods: Through ethical approval, collected in June 2012 to June 2018 in Peking university first hospital uropoiesis surgical department confirmed by surgery pathology of renal cell carcinoma of 187 cases of patients with preoperative renal MR image data, with the pathological results as the gold standard, on the basis of renal cell carcinoma TNM staging T staging criteria evaluation: (1) The different sequence images (T2WI, DWI and enhanced scan portal T1WI) can measure the tumor size on the accuracy of the largest. (2) Accuracy of tumor invasion of perirenal/renal sinus fat. (3) Accuracy of thrombus with renal vein tumor. Kappa test was used to evaluate the consistency of multi-parameter MR and surgical pathology to evaluate the T staging of RENAL cell carcinoma. Results: The maximum diametres measured by T2WI, DWI and enhanced T1WI sequence images were (5.22±3.28) cm, (5.03±3.08) cm and (5.31±3.37) cm, respectively. The maximum diametres measured by pathology were (5.24±3.59) cm, and there was no significant difference between the four groups by Wilcoxon rank sum test. The sensitivity, specificity, positive predictive value and negative predictive value were 88.7%, 88.1%, 74.6% and 95.2%, respectively. The sensitivity, specificity, positive predictive value and negative predictive value of MR in the evaluation of renal vein tumor thrombus were 90.9%, 99.2%, 98.0% and 96.4%, respectively. The weighted Kappa value of MR for determining T stage of renal carcinoma and pathological tumor was 0.81. Conclusions: Preoperative multi-parameter MR examination for RCC patients can accurately determine tumor T stage and provide effective information for the selection of clinical treatment.]]></description>
<pubDate>Tue,20 Jul 2021 00:00:00  GMT</pubDate>
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<title><![CDATA[Clinical characteristics and MR imaging features of metanephric adenoma]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2021.07.013</link>
<description><![CDATA[Objective: To document the clinical characteristics and MR imaging features of metanephric adenoma (MA). Materials and Methods: Pathologically-proven MAs with complete MR protocol were retrospectively analyzed between January 2013 and December 2019. The clinical information and MR imaging features were reviewed. Two experienced radiologists in consensus observed the MR imaging features of all the cases. Results: Eleven cases of MA (3 males, 8 females) were enrolled in this study with age of (38.5±12.3) years old. All lesions were solitary. The diameter was (3.7±1.7) cm. Ten lesions were detected during routine health checkup. Two patient presented polycythemia. Ten patients underwent partial nephrectomy, and one radical nephrectomy. All lesions were well-defined, 7 lesions demonstrated exophytic growth, and 7 lesions were adjacent to the renal sinus. Two lesions showed complete pseudocapsule on T2WI and 4 incomplete pseudocapsule. Eight lesions showed cystic degeneration or necrosis and 2 hemorrhage. On T2WI 9 lesions showed inhomogeneous hypointensity, all lesion hyperintenisty on DWI, 8 of which showed rim hyperintensity, while on ADC map. All lesions showed hypointensity, 9 of which rim hypointensity. On T1WI 9 lesions showed hypointensity. On contrast-enhanced imaging, the signal intensity of MA lesions was lower than that of renal cortex, and MR lesions demonstrated progressive enhancement pattern. Conclusions: MA is common in young and middle-aged women, with unilateral single mass and no obvious clinical symptoms. The main MR imaging features are mainly exophytic, adjacent to renal sinus at the inner edge, hypointensity on T2WI, no or incomplete pseudocapsule, rim diffusion restriction on DWI, visible cystic degeneration and necrosis, rare hemorrhage, no lipid or fat, and mild progressive enhancement. The characteristics of MR imaging can help clinicians and radiologists to accurately diagnose MA.]]></description>
<pubDate>Tue,20 Jul 2021 00:00:00  GMT</pubDate>
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<title><![CDATA[Value of T2WI-FS based radiomics features in the diagnosis of cervical cancer metastasis and lymph vascular space invasion]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2021.07.014</link>
<description><![CDATA[Objective: To investigate the value of fat-suppression T2-weighted imaging (T2WI-FS) based radiomics features in the diagnosis of cervical cancer (CC) metastasis and lymph vascular space invasion (LVSI). Materials and Methods: The clinical data and image data of 66 CC patients in our hospital from June 2017 to June 2020 were retrospectively analyzed. Preoperative magnetic resonance imaging (MRI) horizontal position T2WI-FS images delineated the region of interest (ROI). Preprocessing image and ROI image were processed using A. K. software. A total of 402 radiomics features were extracted from T2WI-FS images. ANOVA+MW combined with LASSO methods were used to perform dimensionality reduction. Receiver operating characteristic (ROC) curve was used to value of T2WI-FS based radiomics features in the diagnosis of cervical cancer lymphatic metastasis and LVSI. Results: The pathological examination showed that there were 22 cases with lymphatic metastasis and 44 cases without metastasis. The analysis found that lymphatic metastasis was related to the depth of cervical interstitial infiltration and LVSI (all P＜0.01). There were 27 LVSI positive patients and 39 negative patients. Analysis found that LVSI was related to the degree of tissue differentiation, the depth of cervical interstitial infiltration and lymph node metastasis (all P＜0.01). The area under the curve (AUC), sensitivity (Sen) and specificity (Spe) of T2WI-FS imaging radiomics features in the diagnosis of lymphatic metastasis were 0.857, 85.0%, and 86.7%, respectively, and those in the diagnosis of LVSI were 0.807, 68.3% and 88.3%, respectively. Conclusions: Both lymph node metastasis and LVSI are affected by the depth of cervical stromal invasion. T2WI-FS imaging has high efficiency in evaluating lymph node metastasis and LVSI. The preoperative examination is of great significance in guiding surgical treatment and predicting prognosis of cervical cancer patients.]]></description>
<pubDate>Tue,20 Jul 2021 00:00:00  GMT</pubDate>
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<title><![CDATA[The correlation between intravoxel incoherent motion and microvessel density and pathological differentiation of cervical cancer]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2021.07.015</link>
<description><![CDATA[Objective: To analyse the value of intravoxel incoherent motion (IVIM) diffusion weighted imaging and histological microvessel density (MVD) in grading of cervical cancer and to investigate their correlation. Materials and Methods: Twenty-six patients with pathologically proved cervical cancer were analysed retrospectively. They were divided into G1 group (highly differentiated), G2 group (moderately differentiated) and G3 group (poorly differentiated) according to pathology grading of cervical cancer. All patients underwent IVIM MRI. The IVIM parameters (ADC, D, D*, f, fD*) were assessed. And these parameters were correlated with MVD. The MVD were determined with the CD34 stain. Kruskal-Wallis H test was used to compare differences of parameters among three groups. Spearman<sup><sup>,</sup></sup>s rank correlation analysis was used to evaluate the correlation of parameters and pathology grading and the correlation between IVIM parameters and MVD. Results: IVIM parameters, like D value and D* value, showed statistical difference among three groups (P=0.009 、 P=0.003). Pairwise comparison showed that D had significant difference (P＜0.05). Comparing with G1 and G3, G2 and G3, D* value showed significant difference. D value decreased with the increase of differentiation level (that is, the lowest median value of D value in the low-differentiation group). While the value of D* decreased gradually with the increase of differentiation level. The MVD was statistically significant among the three groups (P＜0.05). The correlation between IVIM parameters D* value and MVD was statistically significant (P＜0.05), showing a linear correlation (r2=-0.554). Conclusions: IVIM parameters (D、D*) and MVD have certain diagnostic value for cervical cancer grading. Besides, D* might be used in the noninvasive evalution of MVD.]]></description>
<pubDate>Tue,20 Jul 2021 00:00:00  GMT</pubDate>
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<title><![CDATA[MRI features and pathological mechanism of solitary plasmacytoma in the spine]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2021.07.016</link>
<description><![CDATA[Objective: To explore the MRI features and pathological mechanism of solitary plasmacytoma of the spine (SPS), so as to improve the understanding and diagnosis of SPS and provide the basis for treatment. Materials and Methods: MRI data of 17 patients with SPS confirmed by surgery and pathology were retrospectively analyzed. The MRI features and pathological mechanism were analyzed. Results: The tumors were located in cervical vertebrae in 1 case, thoracic vertebrae in 8 cases and lumbar vertebrae in 8 cases. Seventeen cases of SPS showed varying degrees of osteolytic bone destruction, mild swelling changes. Fourteen cases involving accessories, 13 cases of vertebral compression wedge. Thirteen cases of vertebral edge formation of asymmetric soft tissue masses, 12 cases of soft tissue masses protruding into the spinal canal, 7 cases surrounding the spinal canal to form a "encircling sign". Tumor mostly showed isointensity or slightly hypointensity on T1WI, and isointensity or slightly hyperintensity on T2WI. Enhanced scans were clearly and uniformly enhanced, 14 cases showed "mini brain like" sign. Histopathological features: the tumor cells are composed of small round cells with diffuse and dense arrangement, almost no intercellular matrix. Immunophenotype: 17 cases expressed CD138 and CD38, 12 cases expressed KAP, 7 cases expressed Lambda, 11 cases expressed CD79a, only 2 cases expressed CD20. Conclusions: The MRI features of SPS have certain characteristics. Understanding its MRI features and related pathological mechanism can be helpful to differentiate SPS from other single spinal tumors and improve the accuracy of preoperative diagnosis.]]></description>
<pubDate>Tue,20 Jul 2021 00:00:00  GMT</pubDate>
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<title><![CDATA[Advances in repetitive transcranial magnetic stimulation and magnetic resonance imaging in depression]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2021.07.021</link>
<description><![CDATA[Depression, as a mood disorder, has become the main course of global disability. It has affected more than 300 million people worldwide and can even lead to suicide in severe cases. Repetitive transcranial magnetic stimulation (rTMS), as a non-invasive antidepressant therapy, can improve the symptoms of patients with depression by using pulsed magnetic fields, which can act on the central nervous system to affect brain metabolism and neuroelectrical activity. This article summarizes from these following aspects—— the therapeutic targets and modes of rTMS and the effect evaluation of rTMS through magnetic resonance imaging, in order to improve the understanding of rTMS in ameliorating the core symptoms of depression.]]></description>
<pubDate>Tue,20 Jul 2021 00:00:00  GMT</pubDate>
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<title><![CDATA[Advances in imaging study on grading and typing of meningiomas]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2021.07.022</link>
<description><![CDATA[Meningiomas are the second most common intracranial tumors, most of which are benign and have a good prognosis. Compared with grade Ⅰ meningiomas, grade Ⅱ and Ⅲ meningiomas of the World Health Organization (WHO) have the characteristics of malignant growth, exuberant mitosis, rapid growth and uneven growth, and the doubling time of the tumor is short. Patients with grade Ⅱ and Ⅲ meningiomas are often treated by surgery combined with radiotherapy and chemotherapy, which are easy to relapse and metastasize after operation. Different subtypes of meningiomas are treated differently because of their different tissue components. Therefore, the preoperative non-invasive classification and classification of meningiomas, especially the accurate classification of grade Ⅱ and Ⅲ meningiomas were of great significance for the choice of clinical treatment. Traditional CT and MRI are the most commonly used and mature imaging methods for meningiomas, but the hemodynamic information of meningiomas can not be obtained. there are still some deficiencies in qualitative diagnosis, selection of clinical treatment, evaluation of prognosis, evaluation of curative effect and prediction of recurrence of meningiomas. With the application of new techniques such as energy spectrum CT, MRI functional imaging and molecular imaging, the diagnostic accuracy has been improved. In recent years, the rise of artificial intelligence can more effectively and non-invasively predict the classification of meningiomas and further improve the accuracy of preoperative diagnosis. This article reviews the imaging studies on the grading and classification of meningiomas.]]></description>
<pubDate>Tue,20 Jul 2021 00:00:00  GMT</pubDate>
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<title><![CDATA[MRI research progress of white matter lesions and related vascular cognitive impairment]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2021.07.023</link>
<description><![CDATA[By searching the literatures about white matter lesion (WML) and vascular cognitive impairment (VCI) and their internal correlation, the internal correlation and central mechanism of WML and VCI are gradually discussed from the aspects of etiology of WML, cognitive impairment caused by WML and possible internal mechanism of VCI caused by WML, so as to provide theoretical basis for clinical prevention and treatment. MRI technology plays an important role in clinical cognitive research with its unique advantages. It can improve the detection rate of VCI and provide reliable technical means for its mechanism research.]]></description>
<pubDate>Tue,20 Jul 2021 00:00:00  GMT</pubDate>
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<title><![CDATA[Research progress of DTI quantification in myelopathy]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2021.07.024</link>
<description><![CDATA[At present, there are many limitations in spinal magnetic resonance imaging. In recent years, with the application of diffusion tensor imaging (DTI), the quality of spinal imaging has been improved, and quantitative measurement has become possible, and it has been gradually applied in the diagnosis of various spinal diseases. In this paper, DTI imaging of spinal cord was studied in healthy spinal cord, amyotrophic lateral sclerosis (ALS), spinal cord compression, myelitis, multiple sclerosis. The applications of spinal cord injury (SCI), spinal cord injury (MS) and tumor were reviewed. DTI imaging of spinal cord can not only quantitatively describe the diffuse characteristics of healthy spinal cord, but also early diagnose various spinal cord diseases and define the lesion range, monitor the progress of the disease and evaluate the postoperative recovery.]]></description>
<pubDate>Tue,20 Jul 2021 00:00:00  GMT</pubDate>
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<title><![CDATA[Research progress of PET/MR imaging of carotid atherosclerotic plaque]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2021.07.025</link>
<description><![CDATA[Carotid atherosclerosis is recognized worldwide as an important factor leading to ischemic stroke and transient ischemic attack. In the past, many clinical trials used to measure the degree of carotid artery stenosis as a means of risk stratification. With the advancement of vascular imaging technology, it is now possible to stratify the risk of cerebrovascular accidents in patients not only according to the degree of carotid artery stenosis, but also according to the fragility of plaque rupture. People realize that the stability and vulnerability of the plaque are more important than the degree of stenosis. Because atherosclerotic diseases are driven by dynamic biological processes (inflammation is a key component), imaging plaque biology and plaque structure may provide important insights. Carotid PET/MR imaging is non-invasive. It can not only identify high-risk plaques, but also measure and detect plaque burden and activity. This review reviews the role of different tracers for state-of-the-art PET/MR imaging of atherosclerotic plaques, including the principles of this imaging method, current limitations, and future applications.]]></description>
<pubDate>Tue,20 Jul 2021 00:00:00  GMT</pubDate>
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<title><![CDATA[Progress in evaluation of left ventricular diastolic function by cardiac magnetic resonance]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2021.07.026</link>
<description><![CDATA[Diastolic dysfunction (DD) is a risk factor for adverse cardiovascular events. Assessment of diastolic function is vital in treatment monitoring and prognosis prediction for patient with heart failure. The evaluation methods of DD include: cardiac catheterization, echocardiography, cardiac magnetic resonance (CMR). CMR possess multiple advantages in the evaluation of diastolic function, such as accurate quantification of global and regional ventricular function, hemodynamic analysis. This article reviews the main methods and research prognosis of DD assessment by cardiac magnetic resonance.]]></description>
<pubDate>Tue,20 Jul 2021 00:00:00  GMT</pubDate>
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<title><![CDATA[Advances in the application of artificial intelligence in cardiovascular imaging]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2021.07.027</link>
<description><![CDATA[The advances in computing power and the explosion of data have ushered in the third wave of artificial intelligence. Artificial intelligence has brought convenience to imaging medicine and promoted the development of imaging medicine. Currently, the prevalence of cardiovascular diseases in China is on the rise, and the application of artificial intelligence as a new technology in the field of cardiovascular imaging has great potential. This paper summarizes the current situation of artificial intelligence in this field.]]></description>
<pubDate>Tue,20 Jul 2021 00:00:00  GMT</pubDate>
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<title><![CDATA[Application progress of MR radiomics in neoadjuvant chemotherapy for breast cancer]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2021.07.028</link>
<description><![CDATA[Individual differences and tumor heterogeneity affect the efficacy of neoadjuvant chemotherapy for breast cancer, so it is necessary to seek accurate and reliable non-invasive imaging modalities to early evaluate the efficacy of neoadjuvant chemotherapy for breast cancer. As a new diagnostic tool, radiomics is applied to the high-order feature analysis of tumors, which makes up for the deficiency of traditional MRI in evaluating tumor heterogeneity, and combines imaging, clinical and pathological data to improve the accuracy of diagnosis. This article mainly reviews the application value and challenges of MR radiomics in neoadjuvant chemotherapy for breast cancer.]]></description>
<pubDate>Tue,20 Jul 2021 00:00:00  GMT</pubDate>
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<title><![CDATA[Current status of whole-body magnetic resonance imaging in prostate cancer]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2021.07.029</link>
<description><![CDATA[The incidence of prostate cancer in China is increasing year by year. Metastatic prostate cancer accounts for a large proportion of newly diagnosed prostate cancer patients. Determining the metastatic burden of prostate cancer is critical for the selection of treatment methods and predicting prostate cancer prognosis. Whole-body magnetic resonance imaging (WB-MRI) can accurately assess the metastatic burden of prostate cancer and the treatment efficacy. Compared with positron emission tomography and computed tomography (PET-CT), WB-MRI has the advantages of low price, non-invasive, non-radiation, and no need for contrast agent. This article mainly reviews the application status of WB-MRI in prostate cancer and provides references for the clinical application and further research of WB-MRI.]]></description>
<pubDate>Tue,20 Jul 2021 00:00:00  GMT</pubDate>
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