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<title>Chinese Journal of Magnetic Resonance Imaging RSS feed</title>
<link>http://med-sci.cn/cgzcx/en/contents_list.asp?issue=201509</link>
<language>zh-cn</language>
<copyright>An RSS feed for Chinese Journal of Magnetic Resonance Imaging</copyright>
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<title><![CDATA[The relative level of choline: the value in the preoperative evaluation of cerebral glioma grading and the correlation with cell proliferation in gliomas]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.3969/j.issn.1674-8034.2015.09.001</link>
<description><![CDATA[Objective:  To investigate the value of the relative level of choline measured by proton magnetic resonance spectroscopy in the preoperative evaluation of cerebral gliomas grading and the correlation with cell proliferation in gliomas. Materials and Methods: Fifty-eight patients with cerebral gliomas confirmed by histopathology were collected. All patients were performed with 1H-MRS. On the basis of the histopathological diagnosis, the patients were classified into three groups: grade  Ⅰ—Ⅱ(low-grade), 25 cases, grade Ⅲ, 19, grade Ⅳ, 14. Those whose grades were Ⅲ or Ⅳ were classified into high-grade gliomas group that included 33 cases. The regions of the maximum Cho/Cr value in solid portion of the tumors and the contralateral normal white matter were selected as regions of interest (ROI). The values of Cho/NAA, Cho/Cr, relative Cho/NAA (rCho/NAA) and relative Cho/Cr (rCho/Cr) of ROIs were obtained. Ki-67 grading was defined as follow: labeling index (LI) <5% is negative (－), 5%≤LI<25% is weakly positive(+), 25%≤LI<50% is positive (++), and LI ≥50% is strongly positive (+++). The differences of parameters of the relative level of choline among three groups were analyzed, if the parameters of the relative level of choline had no significant difference between grade Ⅲ and Ⅳ gliomas, we compared the difference between low-grade and high-grade gliomas. The optimum diagnostic thresholds of the parameters were achieved by using receiver operating characteristic curve (ROC), and we calculated the area under the curve (AUC), sensitivity, specificity and accuracy. The correlation between Ki-67 grading and glioma grading, and the correlation between Ki-67 grading and parameters of the relative level of choline were analyzed. Result: The Cho/NAA, Cho/Cr, rCho/NAA and rCho/Cr values of solid portions of tumor of grade Ⅲ and grade Ⅳ gliomas were significantly higher than that of grade Ⅰ—Ⅱ gliomas (P<0.05), however, there was no significant difference between grade Ⅲ and grade Ⅳ gliomas (P>0.05). There were significant differences between low-grade and high-grade gliomas (P<0.05). In the parameters of the relative level of choline to differentiate high-grade gliomas from low-grade gliomas, the accuracy of Cho/NAA was the highest, which equaled to 81.0%, and the threshold was 3.04. The AUC of rCho/Cr was maximum, which was 0.823, and the threshold and accuracy were 2.70 and 77.6%, respectively. There was significant difference between different grade gliomas in Ki-67 grading, and there was a positive correlation between Ki-67 grading and gliomas grading (r=0.741, P<0.05). Cho/NAA, Cho/Cr and rCho/Cr had positive correlation with Ki-67 grading (r were 0.313, 0.444 and 0.336, respectively, P<0.05).  Conclusions: The relative level of choline is a great indicator that can indicate the state of gliomas cell proliferation and evaluate the level of malignant, it is helpful for classification of cerebral gliomas grading before operation.]]></description>
<pubDate>Sun,20 Sep 2015 00:00:00  GMT</pubDate>
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<title><![CDATA[Geographical characteristic of patients with glioblastoma]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.3969/j.issn.1674-8034.2015.09.002</link>
<description><![CDATA[Objective: To provide a basis for decision-making in relocating the medical institute outside by exploring the geographical characteristic of patients with glioblastoma from the 5-year data of the institute. Materials and Methods: The data of 917 patients with glioblastoma were retrospectively analyzed, focused on the geographical distribution and dynamic change in number. All of the patients underwent operation in recent five years in the medical institute. Patient age and gender were compared among those from different geographical regions  Results: Patients from the local region were only 19.4% (178/917). Most of the patients were from adjacent eight geological regions. Patient gender showed no significance among different regions (χ2=7.488, P=0. 485), but the age was different (P=0.005).The oldest patients were from the local region (53.0±13.2 years).  Conclusions: The neurosurgical influence of the medical institute spreads from the local to the adjacent regions. The patients are mainly from regions out of Beijing with a minimal possibility of being influenced by relocated institute.]]></description>
<pubDate>Sun,20 Sep 2015 00:00:00  GMT</pubDate>
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<title><![CDATA[Comparison of susceptibility weighted imaging and TOF-MR angiography for the detection of middle cerebral artery thrombi in acute ischemic stroke]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.3969/j.issn.1674-8034.2015.09.003</link>
<description><![CDATA[Objectives: The aim of this study was to compare the diagnostic accuracy of both methods of susceptibility weighted imaging (SWI) and time-of-flight MR angiography (TOF-MRA) in determining middle cerebral artery occlusion in patients with acute ischemic stroke.  Materials and Methods: Sixty-one patients who presented with clinical symptoms for acute ischemic stroke in the territory of the middle (M1, M2/M3) cerebral artery (MCA) were performed with conventional MRI, DWI, SWI and TOF-MRA. The frequency of hypointense susceptibility vessel signs (SVS) on SWI and vessel occlusion or stenosis on TOF-MRA were compared using the McNemar test.  Results: All of the 61 patients displayed hyperintention on DWI in the infarction area. Forty-seven patients showed larger deep medullary vein than the contralateral. Fifty-nine patients displayed a clearly definable SVS on SWI. In 56 patients the SVS was associated with occlusion or stenosis on TOF-MRA. Sensitivity for detection of thrombi within M1 did not show any significant difference between both techniques (98.2% for both SWI and TOF-MRA) while the sensitivity for detection of thrombi within M2/M3 was significantly different (75.0% for SWI versus 37.5% for TOF-angiography, P<0.05).  Conclusions: SWI and TOF-MRA provide similar sensitivity for acute embolic occlusion in stroke while SWI is superior for the detection of embolic occlusion in small, tortuous arterial vessel segments and deep medullary vein.]]></description>
<pubDate>Sun,20 Sep 2015 00:00:00  GMT</pubDate>
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<title><![CDATA[The correlation of tumor volume, peritumoral edema with cerebral glioma histologic grade]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.3969/j.issn.1674-8034.2015.09.004</link>
<description><![CDATA[Objective:  Analyse the VG, VGW and EI to explore the role in the preoperative evaluation of cerebral glioma grade.  Materials and Methods: Five hundred and sixty-five cerebral glioma patients pathologically confirmed were examinated by head conventional MRI during several years. Result: (1) The VG, VGW and EI of high grade cerebral glioma were higher than those of low grade cerebral glioma. (2) The VG and VGW of the same grade cerebral glioma were related to the tumor location. (3) The EI of same grade cerebral glioma had nothing to do with the tumor location. Conclusions: (1) The VG, VGW and EI of high grade cerebral glioma were higher than those of low grade cerebral glioma, and they increased with the growth of malignant degree. (2) The VG and VGW of the same grade cerebral glioma were related to the tumor location. And the difference of low grade glioma in different parts is more significant. (3) The EI of same grade cerebral glioma had nothing to do with the tumor location.]]></description>
<pubDate>Sun,20 Sep 2015 00:00:00  GMT</pubDate>
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<title><![CDATA[The MRI diagnosis and clinical study of intraspinal epidermoid cyst]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.3969/j.issn.1674-8034.2015.09.005</link>
<description><![CDATA[Objective: To discuss the clinical characteristics and MRI diagnostic value of intraspinal epidermoid cyst. Materials and Methods: Twenty-seven cases (male 15 cases, female 12 cases) intraspinal epidermoid cyst with complete clinical and imaging data were diagnosed retrospectively, which confirmed by surgery and pathology. Results: The major clinical manifestations were unilateral or bilateral lower lamb pain, numbness weakness or strength decreased. Location of lesions were 13 in sacrococcygeal region, 4 in lumbosacral vertebral border area, 7 in lumbar segments, and 3 in thoracolumbar border area. Twenty-three lesions were in subdural space, and 4 in the spinal cord. The length of lesions was 2.7—9.0 cm, and the long axis was consistent with the spinal canal. On MRI, 8 cases showed uniformity hypo-intensity, 14 cases showed iso-/hypo- intensity, and 5 cases showed hyper-/hypo- intensity in T1WI. And 6 cases showed uniformity hyper-intensity, 21 cases showed iso-/hyper- intensity in T2WI. In contrast enhancement, only 4 cases showed irregular circular or linear peripheral enhancement. Sixteen cases complicated with other congenital bone deformation. Conclusions: The intraspinal epidermoid cyst most likely occurred congenitally, and often complicated with other congenital developmental malformation, which can be observed by X-ray photography. The intraspinal epidermoid cyst has characteristic MRI findings, which play an important role in its diagnosis and differential diagnosis.]]></description>
<pubDate>Sun,20 Sep 2015 00:00:00  GMT</pubDate>
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<title><![CDATA[Correlation between susceptibility weighted imaging and pathological grade of clear cell renal cell carcinom]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.3969/j.issn.1674-8034.2015.09.006</link>
<description><![CDATA[Objective:  To evaluate the feasibility of SWI in grading clear cell renal cell carcinoma (CRCC) and compare the ability of SWI and necrosis for grading CRCCs. Materials and Methods: Retrospective reviews of 35 patients with pathologically-proven CRCCs were performed. All patients underwent both conventional MRI and SWI examinations. The morphologies of the intratumoral susceptibility signal intensities (ITSS) were classified into hemorrhage and microvessels. The differences of ITSSs and intratumoral necrosis between low- and high-grade CRCCs were assessed. The diagnostic values of ITSSs and necrosis in differentiating low- from high-grade CRCCs were compared. Results: ITSSs were seen in 31 of 35 patients. No ITSSs were seen in 4 patients with low-grade CRCCs. Mean scores of ITSSs were significantly lower in low-grade CRCCs (1.24±0.72) than that in the high-grade CRCCs (2.70±0.48) (P<0.01). No significant necrosis was seen in 10 patients with low-grade CRCCs. There was a significant difference of the presence of intratumoral necrosis between low- and high-grade CRCCs (P<0.05). Sensitivity, specificity, positive (PPV) and negative predictive values (NPV) were for ITSSs: 70.0%, 100%, 100%, and 89.3%, respectively; for necrosis: 100%, 40.0%, 40.0% and 100%. Conclusions: SWI can evaluate ITSSs and can be an alternative to grade CRCCs preoperatively.]]></description>
<pubDate>Sun,20 Sep 2015 00:00:00  GMT</pubDate>
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<title><![CDATA[Clinical value of apparent diffusion coefficient and quantitative parameters of MR dynamic enhancement of rectal cancer]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.3969/j.issn.1674-8034.2015.09.007</link>
<description><![CDATA[Objective:  To study the clinical value of diffusion weighted imaging (ADC) and MR dynamic enhanced quantitative parameters of rectal cancer.  Materials and Methods: Forty-seven patients of rectal cancer and 16 healthy volunteers underwent multiple b value diffusion weighted imaging (b values respectively 0, 800 s/mm2) and MR dynamic enhanced scanning (adopting the technology of LAVA ISO). (1) ADC values were measured, ADC map was obtained at b 800 s/mm2, three points of interest were measured on the lesions, and ADCmean was the average value. (2) Dynamic enhanced datas were inputted to workstation, and the homodynamic parameters, such as Ktrans, Ve and Kep, were obtained by the dynamic model software. The comparison of the two sample by t test. The Pearson analysis of correlation. The significant threshold was set as P<0. 05.  Results: ADCmean, Ktrans and Kep mean of the tumor group were respectively 0.8835×10-3 mm2/s and 2.6680 min-1, 4.7089 min-1, the healthy group respectively 1.34×10-3 mm2/s, 1.548 min-1, and 2.39 /min. It was respectively statistically significant in rectal cancer group and healthy group (P values<0.01). And Pearson correlation was not statistically significant (P values>0.05).  Conclusions: DWI ADCmean and dynamic enhanced quantitative parameters Ktrans and Kep can effectively distinguish tumor or normal rectal tissue quantitatively, and can be the biomarkers of the rectal cancer in the imaging.]]></description>
<pubDate>Sun,20 Sep 2015 00:00:00  GMT</pubDate>
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<title><![CDATA[A study of diffusion tensor imaging characteristics of uterine fibroids with homogeneous hypointense signal on T2WI]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.3969/j.issn.1674-8034.2015.09.008</link>
<description><![CDATA[Objective: To observe the DTI characteristics of uterine fibroids with homogeneous hypointense signal on T2WI, including the comparison with normal muscle layers, and the difference of DTI parameters between fibroids at different location. Materials and Methods: Sixty-five patients with uterine fibroids were performed routine MRI scanning, enhanced scanning and DTI scan. Eighty uterine leiomyomas were analyzed, including 42 intramural hysteromyoma and 38 subserous fibroids. The fractional anisotropy (FA), mean diffusivity (MD) and relatively anisotropy (RA) of all lesions and normal muscle layers were calculated, all data were analyzed through Independent-Samples t test by SPSS 19.0. Results: MD values of hysteromyomas with homogeneous hypointense signal on T2WI was (1.275±0.204)×10-3 mm2/s, which was significantly lower than the myometrium, FA values (0.465±0.114) and RA values (0.420±0.110) were higher than the myometrium, but there was no significant difference between the parameters of subserous fibroids and intramural hysteromyoma. Conclusions: The DTI characteristics of uterine fibroids with homogeneous hypointense signal on T2WI had some characteristics, which were different with the normal muscle layer, and the location of hysteromyoma did not have much effect on the characteristics of DTI.]]></description>
<pubDate>Sun,20 Sep 2015 00:00:00  GMT</pubDate>
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<title><![CDATA[MRI findings of posterior root tear of the medial meniscus]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.3969/j.issn.1674-8034.2015.09.009</link>
<description><![CDATA[Objective: To determine the value of MRI for diagnosing the posterior root tear of the medial meniscus. Materials and Methods: MR examinations of 70 patients with the posterior root tear of the medial meniscus confirmed by knee arthroscopies were retrospectively reviewed, including 35 patients with posterior root tear of the medial meniscal (the posterior root tear group) and other 35 patients with medial meniscus tear without root tear (control group). The direct signs and the accompanying signs of posterior root tear were analyzed in the coronal, sagittal and axial planes of MRI. The incidences of the signs of posterior root tear were compared between two groups, the sensitivity and specificity with the direct signs of three planes in detecting posterior roots tear were calculated. Results: The incidences of a radial tear in the axial plane, the crack sign in the coronal and the ghost meniscus sign in the sagittal plane on the posterior root tear group were significantly higher than that on the control group (χ2=58.95, P<0.01. χ2=54.96, P<0.01. χ2=45.13, P<0.01). The sensitivity and specificity with the direct signs of three planes in detecting posterior roots tear were 91.43%, 100%, 94.29%, 100%, 85.71%, 94.29%, respectively. The incidences of the medial meniscus subluxation and the subcortical marrow edema deep to the meniscal root anchor on the posterior root tear group were higher (χ2=11.28，P=0.01；χ2=13.03， P<0.01). The incidences of cartilage lesion of medial tibiofemoral joint were no difference between two groups (P=0.12), the severities of cartilage lesion were higher on the posterior root tear group (P<0.01). Conclusions: The findings of posterior root tear of the medial meniscal were characteristic, MRI is a relatively good method for detection of posterior meniscus root tears.]]></description>
<pubDate>Sun,20 Sep 2015 00:00:00  GMT</pubDate>
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<title><![CDATA[Correlations between MR apparent diffusion coefficient values and prognostic factors of breast invasive ductal carcinoma]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.3969/j.issn.1674-8034.2015.09.010</link>
<description><![CDATA[Objective: To investigate correlations between apparent diffusion coefficient (ADC) values of invasive ductal carcinoma (IDC) and prognostic factors. Materials and Methods: We examined 47 patients by magnetic resonance imaging (MRI) of breast with pathologically confirmed IDC and measured the ADC values of each lesion. The mean ADC values were cross-check analyzed with the prognostic factors.Results: The mean ADC value was (0.957±0.151)×10-3 mm2/s. The mean ADC values of IDC showed inverse correlation with histological grades (r=0.876, P=0.000) and were significantly lower in the cases with large   tumor size (t=2.600, P=0.013), axillary lymph nodes metastasis (t=4.123, P=0.000), ER and PR positive  expression (t=3.557, P=0.003. t=3.599, P=0.002). HER-2 expression showed no significant correlation with ADC values (t=1.399,  P=0.173).  Conclusions: The ADC values were correlated with some prognostic factors and might provide valuable information for the prognosis of IDC.]]></description>
<pubDate>Sun,20 Sep 2015 00:00:00  GMT</pubDate>
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<title><![CDATA[MRI diagnosis of intraosseous ganglion]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.3969/j.issn.1674-8034.2015.09.011</link>
<description><![CDATA[Objective: To explore the MRI features and diagnostic value of the intraosseous ganglion. Materials and Methods: Clinical data and imaging features of 10 cases surgically confirmed of intraosseous ganglion were respectively analyzed. Among these cases, 3 knees, 2 hips and 5 ankles were included. Results: MRI manifestations of lesions showed long T1, T2 signal, round or oval shape with low signal sclerotic rim, 1 case was found low signal interval, 1 case communicated to the joint cavity. Conclusions: Intraosseous ganglion showed characteristic image findings in MRI, MRI can display the characteristic signal and the adjacent involved cartilage lesions and joint relations, it has important clinical value.]]></description>
<pubDate>Sun,20 Sep 2015 00:00:00  GMT</pubDate>
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<title><![CDATA[DTI and SWI application progress on hippocampus in patients withAlzheimer<sup><sup>,</sup></sup>s disease]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.3969/j.issn.1674-8034.2015.09.013</link>
<description><![CDATA[Hippocampus is the main affected location in Alzheimer's disease. Diffusion tensor imaging (DTI) and susceptibility weighted imaging (SWI) are advanced technology of MRI. This review is about the research development on AD hippocampus by DIT and SWI primary measuring index.]]></description>
<pubDate>Sun,20 Sep 2015 00:00:00  GMT</pubDate>
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<title><![CDATA[Technical progress of pituitary adenoma MRI]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.3969/j.issn.1674-8034.2015.09.014</link>
<description><![CDATA[Conventional MRI technique has been widely used in the detection of pituitary lesions. The further spring of some advanced imaging techniques (e.g. magnetic transfer imaging, fast imaging employing steady-state acquisition, perfusion-weighted imaging, diffusion-weighted imaging, MR spectroscopy and etc.) enables the combination of various imaging techniques. It is the combined strategy that improves the detection rate, while significantly contributes to the preoperative evaluation, the surgical method’s election and the follow-up after operations.]]></description>
<pubDate>Sun,20 Sep 2015 00:00:00  GMT</pubDate>
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<title><![CDATA[The clinical application and technology progress of high-resolution MRI in carotid intraplaque hemorrhage]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.3969/j.issn.1674-8034.2015.09.015</link>
<description><![CDATA[Stroke is a leading cause of human death and disability, and carotid vulnerable plaque is closely related to the occurrence of stroke, intraplaque hemorrhage is an important feature of vulnerable plaque. Early identification of carotid plaque composition is crucial for the prevention and control of ischemic stroke. High-resolution MRI with advantages of high tissue resolution, non-invasiveness and repeatability, is an effective method to identify carotid vascular morphology and quantify carotid plaque composition. In recent years, MRI technology to diagnosing intraplaque hemorrhage rapidly and accurately is develop continuingly. In this paper, we made an overall review on MRI clinical applications and technical progress incarotid intraplaque hemorrhage.]]></description>
<pubDate>Sun,20 Sep 2015 00:00:00  GMT</pubDate>
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<title><![CDATA[Research advancements of single-domain antibody in molecular imaging of prostate cancer]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.3969/j.issn.1674-8034.2015.09.016</link>
<description><![CDATA[In the present, prostate cancer still remains one of the most common malignancy afflicting elderly men and its morbidity and mortality significantly increase with population aging, which makes prostate cancer remain a major global cancer problem. Earlier diagnosis and treatment is an essential strategy for better survival rate in prostate cancer. Single-domain antibody (SdAb) is an antigen-specific, variable fragment of camelid heavy chain-only antibody. The smaller size, better stability and ability to recognize and combine with unique epitope specifically as an affinity reagent have made SdAb a useful class of biomolecular for study and diagnostic and therapeutic application in malignancy. In this summary, we review the current relevant studies on SdAb for prostate cancer in molecular imaging, which may provide a new train of thought for future study and clinical application.]]></description>
<pubDate>Sun,20 Sep 2015 00:00:00  GMT</pubDate>
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