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<title>Chinese Journal of Magnetic Resonance Imaging RSS feed</title>
<link>http://med-sci.cn/cgzcx/en/contents_list.asp?issue=201909</link>
<language>zh-cn</language>
<copyright>An RSS feed for Chinese Journal of Magnetic Resonance Imaging</copyright>
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<title><![CDATA[Study of cerebral microstructure in patients with cerebral small vessel disease on intravoxel incoherent motion]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2019.09.001</link>
<description><![CDATA[Objective: To investigate the feasibility of intravoxel incoherent motion (IVIM) in cerebral small vessel disease by studying microvasculature and parenchyma. Materials and Methods: Sixty-six patients with cerebral small vessel disease and thirty controls were retrospectively studied. IVIM images were used to measure the perfusion volume fraction f and parenchymal diffusivity D of the normal appearing white matter, deep grey matter, cortex and white matter hyperintensity. Group differences of them were investigated. Results: There were significant differences in the perfusion volume fraction f between two groups in the normal appearing white matter (t=2.548, P=0.011), deep grey matter (t=1.988, P＜0.001) and cortex (t=2.731, P=0.023). The perfusion volume fraction f (×10-2) of patients (normal appearing white matter 2.32±0.03, deep grey matter 2.94±0.04 and cortex 2.53±0.04) is higher than that of controls (normal appearing white matter 2.21±0.03, deep grey matter 2.68±0.05 and cortex 2.41±0.04). There were significant differences in the parenchymal diffusivity D between two groups in the normal appearing white matter (t=2.003, P=0.002), deep grey matter (t=2.186, P=0.003), cortex (t=2.569, P=0.012) and white matter hyperintensity (t=2.926, P=0.031). The parenchymal diffusivity D (×10-4) of patients (normal appearing white matter 7.34±0.04, deep grey matter 7.76±0.05, cortex 7.42±0.03 and white matter hyperintensity 9.37±0.10) is higher than that of controls (normal appearing white matter 7.16±0.04, deep grey matter 7.55±0.05, cortex 7.31±0.04 and white matter hyperintensity 8.94±0.12). Conclusions: The perfusion volume fraction f and parenchymal diffusivity D of the normal appearing white matter, deep grey matter and cortex in patients with cerebral small vessel disease are significantly higher than those in controls. IVIM can show anomalies in the perfusion volume fraction f and parenchymal diffusivity D. This suggests that IVIM imaging can help to detect and monitor the progression of cerebral small vessel disease.]]></description>
<pubDate>Fri,20 Sep 2019 00:00:00  GMT</pubDate>
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<title><![CDATA[The value of SWI and 3D-ASL in grading of gliomas]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2019.09.002</link>
<description><![CDATA[Objective: To evaluate the value of susceptibility weighted imaging and three-dimensional arterial spin labeling in identification of gliomas. Materials and Methods: Ninety-two patients with glioma (35 Ⅱ, 13 Ⅲ and 44 Ⅳ) were enrolled. All cases underwent SWI and 3D-ASL scans before operations and were confirmed by postoperative pathology. Intratumoral susceptibility signal intensity (ITSS), the maximal cerebral blood flow value (CBFmax), r1 (CBFmax/unaffected contralateral white matter area CBF1), r2 (CBFmax/unaffected contralateral gray matter area CBF2), r3 (CBFmax/contralateral mirror area normal brain tissue CBF3) were obtained by post-processing. Then did statistical analysis. The value of the ITSS was analyzed by non-parametric Mann-Whitney U test. The values of the 3D-ASL parameters were analyzed by one-way ANOVA. P＜0.05 was indicated as the statistically significant difference. Receiver operating characteristic (ROC) curve analysis was used to evaluate the performance of ITSS and 3D-ASL in discriminating between various grades of tumors. Results: The differences of ITSS in (Ⅱ vs. Ⅲ), (Ⅱ vs. Ⅳ) and (Ⅲ vs. Ⅳ) were statistically significant, and higher grades of gliomas showed higher ITSS scores (P＜0.05). But the CBFmax, r1, r2 and r3 were statistically significant just in the group of (Ⅱ vs. Ⅳ)(P＜0.05). The area under the curve (AUC), sensitivity and specificity of the combination of SWI and 3D-ASL were biggest. Conclusions: By combing SWI and 3D-ASL, the diagnostic efficacy of grading gliomas was greatest than that of a single technique, and SWI was more effective than 3D-ASL.]]></description>
<pubDate>Fri,20 Sep 2019 00:00:00  GMT</pubDate>
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<title><![CDATA[Investigating the changes of ALFF of hearing related cortex of infants with sensorineural hearing loss by using fMRI]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2019.09.003</link>
<description><![CDATA[Objective: To study the changes of low frequency amplitude (ALFF) in hearing related brain regions of children with bilateral congenital severe sensorineural deafness (BCSSD) using resting-state functional magnetic resonance imaging (rs-fMRI). Materials and Methods: Twenty-five children (0—4 years old) with BCSSD were recruited in this study and they were divided into two groups: 16 “younger” children with ages below 2 years old and 9 “older” children with ages above 2 years old. Twenty age-matched healthy children (9 in the “younger” group and 11 in the “older” group) were also recruited as controls. All rs-fMRI scans were performed on a 3.0 T GE scanner (discovery 750 w). Data were analyzed to produce ALFF values in different brain regions. Results: In the “younger” group, patients with BCSSD had higher ALFF values compared to healthy controls in left anterior cuneiform lobe, right superior frontal gyrus, right middle occipital gyrus and right parietal lobule. Patients also showed lower ALFF values in left superior temporal gyrus and left inferior frontal gyrus. In the “older” group, patients with BCSSD had higher ALFF values in left anterior cingulate gyrus and left infratemporal gyrus. On the contrary, lower ALFF values were found in left inferior frontal gyrus and left superior temporal gyrus in patients, compared to healthy controls. Comparisons were also performed within the patient group, our results showed that “younger” patients had higher ALFF values in left superior temporal gyrus, left inferior frontal gyrus and insula, and had lower ALFF values in right medial frontal gyrus and left inferior temporal gyrus, compared to “older” patients. Conclusions: The results in this study indicate that functional remodeling may occur in the auditory sensory cortex of children with BCSSD. Functional magnetic resonance imaging can be used as a potential tool to assist preoperative evaluation and prognosis judgement of cochlear implants.]]></description>
<pubDate>Fri,20 Sep 2019 00:00:00  GMT</pubDate>
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<title><![CDATA[Preliminary study of magnetic resonance dynamic contrast enhancement combined with diffusion weighted imaging to identify high grade glioma recurrence and treatment-related changes]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2019.09.004</link>
<description><![CDATA[Objective: To investigate the value of dynamic contrast enhanced magnetic resonance imaging (DCE-MRI) and diffusion weighted imaging (DWI) in identifying recurrence and treatment-related changes of high grade glioma. Materials and Methods: Thirty-two patients with cerebral glioma resection and abnormal enhancement after radio-chemotherapy (22 patients had recurrence and 10 patients had treatment-related changes) were collected. All patients undergone routine magnetic resonance imaging, enhancement, DWI, DCE imaging within 2 months after the radio-chemotherapy. Ktrans, Kep, Ve, iAUC perfusion pseudo-color map and ADC map were obtained using post-processing work station, and their values of enhancement region were also calculated separately. The differences in parameters between recurrence and treatment-related changes were evaluated using Wilcoxon test, and the receiver operating characteristic (ROC) curve was plotted to calculate sensitivity and specificity with the area under the curve. Results: The higher Ktrans and iAUC values were observed in recurrence group (P＜0.05). The area under Ktrans and iAUC curves were 0.973 and 0.941,the sensitivity and specificity were 95.5%, 95.5% and 90%, 80% respectively, using the threshold of 0.128 and 0.152. The recurrence group had the lower average ADC value than the treatment-related changes group (P＜0.05), and the area under the average ADC curve was 0.864 (sensitivity and the specificity of 86.4% and 80%, respectively). The Ktrans value had the highest diagnostic efficacy, the sensitivity can improve to 100% on detecting recurrence when incorporating Ktrans and ADC values. Conclusions: DCE-MRI combined with DWI has important clinical value on the differential diagnosis between recurrence and treatment-related changes in high grade glioma.]]></description>
<pubDate>Fri,20 Sep 2019 00:00:00  GMT</pubDate>
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<title><![CDATA[fMRI study of inhibitory control network in heroin addicts with different genotypes of DRD2 TaqIA]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2019.09.005</link>
<description><![CDATA[Objective: To investigate the differences in inhibition control networks between different genotype heroin addicts of DRD2 TaqIA. Materials and Methods: A total of 57 heroin addicts were recruited. The DRD2 TaqIA gene type was divided into A+ group and A-type group, matching 46 healthy individuals. Firstly, three groups of impulsive scales were evaluated, and then the right inferior frontal gyrus was used as the whole brain functional connection. Results: The differences brain network were statistically analyzed between the heroin group and the healthy control group, the A+ group and the A-type group. The total scores of impulses, behavioral impulses and unplanned impulses in heroin group were significantly higher than those in normal group, but there was no significant difference between type A+ group and A- type group. Compared with the normal group, the functional connections between the right inferior frontal gyrus and bilateral posterior cingulate, anterior cuneiform, lingual gyrus and talus gyrus were enhanced, and bilateral parietal lobe were decreased in heroin addiction group. Compared with the A-type group, the functional connections between the right inferior frontal gyrus and cerebellum were enhanced, and bilateral anterior cingulate, medial prefrontal and left insular lobes were decreased in A+ type group. Conclusions: Heroin addicts have higher psychological impulsivity and abnormal control network; compared with A-genotype, A+ genotype heroin addicts have less inhibition and control ability, and may be more likely to take drugs or relapse.]]></description>
<pubDate>Fri,20 Sep 2019 00:00:00  GMT</pubDate>
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<title><![CDATA[Clinical application of bi-ventricular strains in ischemic cardiomyopathy and non-ischemic dilated cardiomyopathy]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2019.09.006</link>
<description><![CDATA[Objective: The purpose of this study was to evaluate if cardiac magnetic resonance feature-tracking (MR-FT) could be applied to detect the differences of both ventricular function between ischemic cardiomyopathy (ICM) and non-ischemic dilated cardiomyopathy (NIDCM). Materials and Methods: Twenty-five subjects with NIDCM and 14 subjects with ICM underwent cardiac magnetic resonance imaging and late gadolinium enhancement (LGE). Cardiac function including global and segmental strains of both ventricles was analyzed using feature tracking technology to obtain myocardial 3D strain parameter values in all directions. Analysis of Mann-Whitney U-test or t-test were used for above parameters. For those significant different parameters, Pearson linear correlation analysis and Logistic regression analysis was carried out. For RVEF and RV LS, receiver operating characteristic (ROC) curve was used to analyze their diagnostic performance in distinguishing NIDCM from ICM. Results: Compared with ICM, both ventricular ejection fractions significantly decreased (P＜0.001) and all global strain indicators of LV significantly decreased in the NIDCM (P＜0.01). Left ventricular ejection fraction (LVEF) in NIDCM was correlated with both circumferential strain (r=-0.849, P＜0.001) and longitudinal strain (r=-0.759, P＜0.001) significantly. LVEF in ICM was correlated with radial strain (r=0.735, P＜0.01), circumferential strain (r=-0.746, P＜0.01) and longitudinal strain (r=-0.708, P＜0.01) significantly. The peak values of radial strain, circumferential strain and longitudinal strain of LGE-positive myocardial segments in two groups were lower than those in LGE-negative ones [ICM: (32.77±27.40)% vs (52.22±29.16)%, (-26.16±14.90)% vs (-31.43±12.80)%, (-18.29±9.80%) vs (-23.54±11.70)%, P＜0.001. NIDCM: (14.99±20.47)% vs (22.36±21.92)%, (-11.53±7.77)% vs (-14.70±8.31)%, (-11.85±7.20)% vs (-13.94±7.99)%, P＜0.001]. The peak values of radial strain, circumferential strain and longitudinal strain of LGE-negative myocardial segments in NIDCM were lower than ICM [(14.99±20.47)% vs (32.77±27.40)%, (-11.53±7.77)% vs (-26.16±14.90)%, (-11.85±7.20)% vs (-18.29±9.80)%, P＜0.01]. Conclusions: MR-FT can evaluate the bi-ventricular function of NIDCM and ICM from both global and local aspects, especially in the right ventricle, so as to provide more evidence for clinical diagnosis and treatment.]]></description>
<pubDate>Fri,20 Sep 2019 00:00:00  GMT</pubDate>
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<title><![CDATA[Diagnostic performance of diffusion weighted imaging for differentiating benign and malignant gallbladder lesions: a Meta-analysis]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2019.09.007</link>
<description><![CDATA[Objective: To evaluate the diagnostic value of diffusion weighted magnetic resonance imaging in patients with gallbladder lesions by Meta-analysis. Materials and Methods: Based on validity criteria for diagnostic research published by PubMed, EMbase, Web of Science, The Cochrane Library, CNKI, Wanfang Data, CBM and VIPfrom inception to December 2018, to search the differentiation of gallbladder lesions with diffusion weighted imaging (DWI) . Two investigators independently screened literature according to the inclusion and exclusion criteria, extracted data, and assessed the risk of bias of included studies by using the QUADAS-2 tool and Review Manager 5.3, and then Meta-analysis was conducted using Stata 12.0 software. Results: A total of 13 articles were included (8 English, 5 Chinese). The results of Meta-analysis showed that, the pooled sensitivity (Sen), specificity (Spe), positive likelihood ratio (+LR), negative likelihood ratio (-LR), diagnostic odds ratio (DOR) of DWI for differentiating benign and malignant gallbladder lesions were 0.88(95%CI, 0.78—0.94), 0.85(95%CI, 0.79—0.89), 5.84(95%CI, 3.97—8.59), 0.14(95%CI, 0.07—0.28), 41.88 (95%CI, 15.42—113.69), and the area under summary receiver operating characteristic (SROC) curve of DWI for differentiating benign and malignant gallbladder lesions is 0.93, Q*=0.86. The pooled Sen, Spe, +LR, -LR, DOR of apparent diffusion coefficient (ADC) for differentiating benign and malignant gallbladder lesions were 0.79(95%CI, 0.71—0.86), 0.93(95%CI, 0.83—0.97), 10.8(95%CI, 4.7—25.1), 0.22(95%CI, 0.16—0.32), 48(95%CI, 18—127), and the area under SROC curve of ADC for differentiating benign and malignant gallbladder lesions is 0.89, Q*=0.82 respectively. Conclusions: Diffusion weighted magnetic resonance imaging is of great accuracy in differentiating benign and malignant gallbladder lesions.]]></description>
<pubDate>Fri,20 Sep 2019 00:00:00  GMT</pubDate>
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<title><![CDATA[Application value of magnetic resonance T2 mapping imaging in evaluation of knee osteoarthritis cartilage injury]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2019.09.008</link>
<description><![CDATA[Objective: To observe the change of T2 value in cartilage injury and the diagnostic value and clinical significance of T2 mapping imaging in osteoarthritis (OA) cartilage injury. Materials and Methods: Sixty patients with knee osteoarthritis were selected as the observation group and thirty healthy volunteers were selected as the control group. The two group patients underwent GE Signa 3.0 T MRI scanning including conventional and T2 mapping imaging sequence. The average T2 value of cartilage in 7 regions including weight-bearing area and non-weight-bearing area of medial and lateral femoral condyle, medial tibial plateau, lateral tibial plateau and patella cartilage were measured respectively. Results: The average T2 values of cartilage in regions in the observation group were higher compared with the control group (P＜0.05). Except for the medial femoral condyle of the control group, the average T2 values of the weight-bearing areas of medial and lateral femoral condyle of the observation group and lateral femoral condyle of the control group were higher than those of the corresponding non-weight-bearing areas (P＜0.05). The average T2 value of superficial cartilage was higher than that of deep cartilage in the same region except for the weight-bearing area of medial femoral condyle in the observation group (P＜0.05). The average T2 values of the weight-bearing areas of medial and lateral femoral condyle in the severe and mild OA group were both higher compared with the normal group (P＜0.05), however, there was no significant difference in the T2 value of weight-bearing areas of medial and lateral femoral condyle between the severe OA group and the mild OA group (P＞0.05). Conclusions: T2 mapping can detect the changes of cartilage T2 value and it is helpful for OA patients to start treatment without delay, monitor disease progress and conduct the follow-up of cartilage repair.]]></description>
<pubDate>Fri,20 Sep 2019 00:00:00  GMT</pubDate>
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<title><![CDATA[Comparison of 3D non-contrast enhanced foot MR angiography using steady-state free precession with single and multi-directional FSD modules preparation]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2019.09.009</link>
<description><![CDATA[Objective: To compare the image quality of pedal arteries acquired from three-dimensional (3D) non-contrast enhanced magnetic resonance angiography (NCE-MRA) using steady-state free precession (SSFP) sequence with single directional and multi-directional flow-sensitive dephasing (FSD) modules preparation, respectively. Materials and Methods: A total of 32 healthy volunteers and 3 patients with diabetes prospectively underwent 3D NCE-MRA applying ECG (Electrocardiograph)-triggered SSFP sequence with single directional and two directional FSD modules successively in pedal arteries at a 1.5 T MR scanner. Number of diagnostic arterial segments, signal-to-noise ratio (SNR) of pedal artery, contrast-to-noise ratio (CNR) between pedal artery and surrounding muscle, vessel sharpness, and image quality on a four point score of three main segments (dorsal artery, lateral plantar artery, and pedal arch) were statistically compared for the two techniques. Results: No significant difference existed in number of diagnostic arterial segments, SNR, CNR, and vessel sharpness of NCE-MRA images acquired from SSFP sequence with one FSD module applied in only readout direction and two FSD modules applied in both readout and partition-encoding directions (P＞0.05). The image quality scores of NCE-MRA with single directional FSD module was higher than that with two directional FSD modules. However, pedal arch not displayed completely in full length in some images acquired with single directional FSD module was delineated well in images acquired with two directional FSD modules. Conclusions: NCE-MRA using SSFP with multi-directional FSD module could display the pedal arterial segments better than that with only single directional FSD module.]]></description>
<pubDate>Fri,20 Sep 2019 00:00:00  GMT</pubDate>
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<title><![CDATA[New advances in high-resolution magnetic resonance imaging in intracranial atherosclerotic diseases]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2019.09.012</link>
<description><![CDATA[Intracranial atherosclerotic disease is an important cause of ischemic stroke. High-resolution magnetic resonance imaging is the only non-invasive technique that can realize the analysis of the structure of living intracranial arterial wall, which improves the atherosclerotic plaque. The detection rate presents important features related to clinical pathogenesis, and has clear value for guiding clinical treatment. This article reviews the principles and development of high-resolution magnetic resonance imaging techniques and the research progress in intracranial atherosclerotic plaques in the past two years.]]></description>
<pubDate>Fri,20 Sep 2019 00:00:00  GMT</pubDate>
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<title><![CDATA[The diffusion tensor imaging research of subcortical ischemic vascular disease]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2019.09.013</link>
<description><![CDATA[Subcortical ischemic vascular disease (SIVD) is a homogeneous subtype of vascular cognitive impairment (VCI). SIVD is one of the main reasons resulted in cognitive impairment and dementia in old ages. The patients of SIVD give a huge burden to our country and their families. However, the progress of SIVD is reversible. This makes the research of SIVD more important. The research of SIVD's imaging is benefit to predict the disease’s progress and outcome. This will enable us to intervene the progress of SIVD more effectively.]]></description>
<pubDate>Fri,20 Sep 2019 00:00:00  GMT</pubDate>
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<title><![CDATA[Advance researches on MRI in evaluation of pathological differentiation for hepatocellular carcinoma]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2019.09.014</link>
<description><![CDATA[Pathological grade of hepatocellular carcinoma (HCC) is an independent predictor of tumor prognosis. Poorly differentiated HCC has a high recurrence rate and poor prognosis. So accurate grading of HCC is closely related to clinical decision and prognosis prediction. In this paper, MR in the evaluation of preoperative pathological grade of HCC was reviewed.]]></description>
<pubDate>Fri,20 Sep 2019 00:00:00  GMT</pubDate>
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<title><![CDATA[Progress of magnetic resonance elastography in nonalcoholic fatty liver disease]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2019.09.015</link>
<description><![CDATA[In recent years, the prevalence of nonalcoholic fatty liver disease (NAFLD) in China is rising, and has become the largest chronic liver disease in China. Nonalcoholic fatty liver disease (NAFLD) includes nonalcoholic fatty liver disease (NAFL), nonalcoholic steatohepatitis (NASH) and its related liver cirrhosis, hepatocellular carcinoma (HCC). Among them, NASH has a higher risk of developing liver cirrhosis and hepatocellular carcinoma (HCC). Magnetic resonance elastic imaging (MRE) is of great value in the diagnosis and monitoring of the course of NAFLD. This article reviews the basic principle of MRE and its application in NAFLD.]]></description>
<pubDate>Fri,20 Sep 2019 00:00:00  GMT</pubDate>
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<title><![CDATA[A review of the research progress and idea discussion of functional magnetic resonance imaging with Tai Chi]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2019.09.016</link>
<description><![CDATA[The current paper provided a review of the research progress and idea discussion of functional magnetic resonance imaging with Tai Chi. With a series of analysis methods, previous studies indicated that Tai Chi can increase the functional connectivity between many brain regions and networks. Taken together, these results have revealed the possible mechanisms of Tai Chi in postponing the aging degeneration of human brain in the central neural function level. However, previous studies still have some limitations. In the future, detailed large-scale studies are still in need to further confirm the current results.]]></description>
<pubDate>Fri,20 Sep 2019 00:00:00  GMT</pubDate>
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<title><![CDATA[The advances of study on apoptosis molecular imaging through magnetic resonance]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2019.09.017</link>
<description><![CDATA[Apoptosis (programmed cell death) plays key roles in carcinogenesis as well as other diseases including neurodegenerative disorders, cortical necrosis, myocardial infarction, ischemia reperfusion, cell therapy and rejection of organ transplantation. Non-invasive assess of apoptosis is important for diagnosis disease occurrence and development and therapeutic effects judgment. Currently, MRI is one of the widespread non-invasive diagnostic modalities. Specific biomarker of apoptosis conjugated with MR contrast agents has been used to develop molecular MR probe and in preclinical or clinical trial. This study collected literatures on apoptosis molecular MR imaging in recent decade. We summarized the progress of study on utilization of molecular biomarker of apoptosis in MR imaging. We hope our research will provide useful clues for application and extension of molecular MR imaging of apoptosis in clinic.]]></description>
<pubDate>Fri,20 Sep 2019 00:00:00  GMT</pubDate>
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