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<title>Chinese Journal of Magnetic Resonance Imaging RSS feed</title>
<link>http://med-sci.cn/cgzcx/en/contents_list.asp?issue=202109</link>
<language>zh-cn</language>
<copyright>An RSS feed for Chinese Journal of Magnetic Resonance Imaging</copyright>
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<title><![CDATA[Effect of vestibular rehabilitation on spontaneous brain activity in patients with vestibular migraine: a resting state MRI study]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2021.09.001</link>
<description><![CDATA[Objective: To evaluate the effect of vestibular rehabilitation (VR) training on spontaneous neural activity, and to explore the neuropathological mechanism in vestibular migraine (VM) treatment in patients with VM by resting state functional magnetic resonance imaging (fMRI). Materials and Methods: Fourteen patients with VM who were diagnosed for the first time and did not receive VR training within 6 months were included in this study. They were examined with resting state fMRI before and after VR training for one month. The clinical related indexes including Dizziness Handicap Inventory (DHI), Hamilton Depression Scale (HAMD) and Hamilton Anxiety Scale (HAMA) scores were collected. The changes of spontaneous neural activity in VM patients after VR training were observed, and the amplitude of low-frequency fluctuation (ALFF) of brain regions with statistical differences were extracted. The correlation analysis was performed with clinical related scores. Results: After one month of VR training, the ALFF values in the right partial insula and frontal triangle of VM patients were significantly reduced, and the difference was statistically significant (GRF correction, P＜0.05), and the ALFF values in the right insula of VM patients after VR training were positively correlated with the DHI score after VR training (r=0.549, P＜0.05). Conclusions: After VR training, the activity of right insular lobe and part of frontal lobe in VM patients was weakened, which may be the neuropathological mechanism of VM migraine. There was a positive correlation between the degree of symptom relief and the decrease of right insular nerve activity in VM patients.]]></description>
<pubDate>Mon,20 Sep 2021 00:00:00  GMT</pubDate>
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<title><![CDATA[Preliminary application of amide proton transfer-MRI in diagnosis of nasopharyngeal carcinomas]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2021.09.002</link>
<description><![CDATA[Objective: To explore the potential value of applying amide proton transfer weighted imaging (APT-weighted imaging) in nasopharynx. Materials and Methods: From June 2020 to February 2021, 50 patients with pathologically confirmed nasopharyngeal carcinoma (NPC) who have undergone APT-weighted imaging were retrospective enrolled, and their APT-weighted imaging and clinicopathological data were collected. Two radiologists independently evaluated the performance of APT map in depicting the NPC lesion and their consistency was tested using Kendall<sup><sup>,</sup></sup>s Tau-b was used to analyze the consistency of the results by the two radiologists. Paired t-test was used to analyze the consistency in the APT values between the left and right side of temporal muscles, parotid glands, cerebellum and turbinate and the difference in the APT values between nasopharyngeal carcinoma tissue and normal nasopharyngeal left and right temporal muscle, parotid glands, cerebellum and turbinate on the same slice. Student t-test was used to compare APT values between differentiated and undifferentiated subtypes of NPC. Results: In terms of performance of lesion depiction, two radiologists agreed with a correlation coefficient of 0.844. There were no significantly difference in APT values between left and right of temporal muscles, parotid glands, cerebellum, and turbinates (P=0.475, 0.765, 0.443, and 0.544, respectively). The difference in APT values between nasopharyngeal carcinoma lesions and normal nasopharyngeal and parotid gland tissues was not statistically significant (P= 0.338 vs. P=0.664 & 0.933), but the APT values of nasopharyngeal carcinoma lesions were significantly higher than the left and right temporal muscles and cerebellum tissues (P＜0.001), but lower than the turbinate tissue (P＜0.001). When it comes to subtypes of NPC, no significant difference was found in APT values between differentiated 1.97%±0.89% and undifferentiated NPC 1.95%±0.82%. Conclusions: This study showed that APT imaging is satisfactory in depicting nasopharyngeal lesions, and technically feasible in the nasopharyngeal area. APT effect of different tissue types can be accurately quantified in this area, which provides practical experience in clinically applying APT imaging to the nasopharynx.]]></description>
<pubDate>Mon,20 Sep 2021 00:00:00  GMT</pubDate>
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<title><![CDATA[The study of high-resolution diffusion tensor imaging in thyroid-associated ophthalmopathy]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2021.09.003</link>
<description><![CDATA[Objective: To study the application of high-resolution MR diffusion readout-segmented of long variable echo-trains diffusion tensor imaging (Resolve DTI) in the early stage of optic nerve microstructure injury in patients with thyroid associated ophthalmopathy (TAO). Materials and Methods: Thirty TAO patients and 30 age and sex matched healthy controls (HC) were enrolled in this study. Conventional MRI and Resolve DTI sequences were used to scan the orbit respectively. FA, ADC, AD and RD values of bilateral optic nerves were measured. Quantitative parameters related to DTI of bilateral optic nerves were compared between patients and HC. Results: FA value of bilateral optic nerves in TAO patients was significantly lower than that of HC (P=0.009, P=0.003; P＜0.05), ADC and AD value had no significant difference (P=0.364, P=0.053, P=0.955, P=0.211; P＞0.05), and RD value was higher than that of HC (P=0.010, P=0.009; P＜0.05). Conclusions: Resolve DTI imaging technology is helpful to provide objective basis for the damage of the early stage of optic nerve microstructure injury in TAO patients, and to provide help for the treatment of optic neuropathy in TAO patients.]]></description>
<pubDate>Mon,20 Sep 2021 00:00:00  GMT</pubDate>
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<title><![CDATA[Preliminary study on papillary muscle morphology of the left ventricle in patients with hypertrophic cardiomyopathy by cardiac MR imaging]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2021.09.004</link>
<description><![CDATA[Objective: To explore the value of papillary muscle (PM) morphology in patients with hypertrophic cardiomyopathy (HCM) by cardiac magnetic resonance imaging (CMR). Materials and Methods: Seventy-eight patients who underwent CMR from January 2015 to Octorber 2019 in our hospital were enrolled in this study, including 48 cases of patients with HCM and 30 cases of patients with negative CMR. Patients with HCM were divided into HCM with left ventricle (LV) outflow obstructions subgroup (n=10) and without obstructions subgroup (n=38). For each patients, the evaluation of LV end-diastolic volume index (EDVi), end-systolic volume index (ESVi), ejection fraction (EF), and ventricle wall mass index (LVMi) were performed with CVI 42 (Circle Cardiovascular Imaging, Canada), as well as number and mass index of papillary muscles (PMMi). Intra- and interobserver reproducibility was also estimated after four weeks in a random subset of 20 patients, 10 for each group. Independent-samples t test, Spearman<sup><sup>,</sup></sup>s correlation, and Bland-Altman statistics were used. Results: Compared with patients with negative CMR, the PM number, PMMi and LVMi were significantly greater in patients with HCM [(2.4±0.6) vs. (2.1±0.3), (5.8±1.2) g/m2 vs. (2.8±0.5) g/m2, (118.6±21.5) g/m2 vs. (58.4±6.9) g/m2, P＜0.05 respectively]. Moreover, the LVMi and PMMi in patients with LV outflow obstructions were significantly greater than those without obstructions [(131.9±15.3) g/m2 vs. (115.7±21.8) g/m2, (6.8±1.4) g/m2 vs. (5.5±0.9) g/m2, P＜0.05 respectively]. In patients with HCM, PMMi was weakly correlated with the magnitude of LV outflow gradient (r=0.405, P＜0.05). The reproducibility of PMMi measurements was excellent (intraclass correlation coefficients, ICC=0.961, 0.913). The Bland-Altman analysis chart showed only a few spots outside the 95% consistency boundaries. Conclusions: For patients with HCM, PM morphologic abnormalities are common and PMMi correlates with magnitude of LV outflow gradient. CMR can be used to estimate PM morphology with good reproducibility.]]></description>
<pubDate>Mon,20 Sep 2021 00:00:00  GMT</pubDate>
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<title><![CDATA[Study on the value of liver-specific contrast agent MRI abbreviated sequence in screening small hepatocellular carcinoma in high-risk population]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2021.09.005</link>
<description><![CDATA[Objective: To compare the screening ability of three groups of abbreviated MRI sequences for small hepatocellular carcinoma (small hepatocellular carcinoma, sHCC) in a high-risk population of hepatocellular carcinoma (HCC). Materials and Methods: The images of 121 patients with pathological results who underwent full sequence gadoxetic acid-enhanced MR in Henan People<sup><sup>,</sup></sup>s Hospital from January 2017 to October 2020 were collected. Three groups of optimized sequences were extracted from the whole sequence for independent evaluation by two radiologists: (1) Non-contrast group, including T2WI and DWI sequences. (2) Dynamic enhancement group, including four-phase enhanced images of disodium gadolinium (early arterial phase, arterial phase, portal venous phase, equilibrium phase). (3) Hepatobiliary phase group, including T2WI, DWI and 20 min T1-HBP sequences. According to the pathological results, the patients were divided into positive or negative liver cancer, and the diagnostic efficiency of the abbreviated sequence in the three groups was calculated. Results: The scanning and preparation time of the three groups of abbreviated MRI sequences (minutes: seconds) are 12:52, 13:04 and 14:06, respectively. The sensitivity and 95% confidence interval of the three abbreviated sequences for diagnosing small hepatocellular carcinoma were 0.855 (0.750, 0.928), 0.913 (0.820, 0.967), 0.942 (0.858, 0.984), and the specificity was 0.731 (0.590, 0.844), 0.904 (0.790, 0.968), 0.885 (0.766, 0.956). The coincidence rate was 0.802 (0.719, 0.869), 0.909 (0.843, 0.954), 0.917 (0.853, 0.960). The positive likelihood ratios of the three groups were 3.18, 9.51, 8.19, the negative likelihood ratios were 0.19, 0.09, 0.06, and the Youden index was 0.586, 0.817 and 0.827 respectively. Conclusions: The sensitivity of non-contrast group is higher, which is helpful for small hepatocellular carcinoma screening, while the specificity and coincidence rate of dynamic enhancement group and hepatobiliary phase group are higher, and the diagnostic efficacy of screening small hepatocellular carcinoma is better.]]></description>
<pubDate>Mon,20 Sep 2021 00:00:00  GMT</pubDate>
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<title><![CDATA[Diagnostic performance of MRI and CT for hepatocellular carcinoma less than 3cm based on liver reporting and data system version 2018]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2021.09.006</link>
<description><![CDATA[Objective: To investigate the diagnostic value of liver reporting and data system version 2018 (LI-RADS v2018) for diagnosing hepatocellular carcinoma (HCC) less than 3 cm between MRI and CT. Materials and Methods: The data of total 73 patients with HCC less than 3 cm and liver cirrhosis induced by HBV confirmed by pathology from January 2009 to December 2020 were retrospectively analyzed. The CT and MRI features of the HCC lesion were analyzed and categorized according to the LI-RADS v2018. Then the lesions were classified and compared between CT and MRI. The accuracy of LI-RADS v2018 in the diagnosis of HCC were calculated and compared based on pathology. Results: The recognition rate of "capsule" appearance in the major features of HCC was significant higher in MRI than that in CT (P＜0.001). The recognition rates of mild to restricted diffusion (86.3%) was more common than the other ancillary features of HCC in MRI, and mosaic architecture (25.0%) was more common than the other ancillary features of HCC in CT. In comparison of CT and MRI, statistically significant difference were found in the HCC lesions classified based on LI-RADS v2018 (P＜0.001). When adopting LR-4/5 as a predictor of HCC, the accuracy was increased for MRI compared with CT (P=0.046). Conclusions: Based on LI-RADS v2018, the recognition rates of some HCC features and the accuracy of HCC were increased for MRI compared with CT.]]></description>
<pubDate>Mon,20 Sep 2021 00:00:00  GMT</pubDate>
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<title><![CDATA[Tentative discussion on cardiac magnetic resonance in differentiating common types of cardiac amyloidosis]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2021.09.007</link>
<description><![CDATA[Objective: To investigate the role of cardiac magnetic resonance (CMR) in differentiating common types of cardiac amyloidosis (CA). Materials and Methods: Retrospective analysis was performed on 57 cases of CA diagnosed by pathology and undergoing CMR examination, and they were divided into two groups: the cardiac light-chain amyloidosis group (AL-CA group) (n= 37) and the transthyretin-related amyloidosis group (ATTR-CA group) (n=20). The characteristics and scope of late gadolinium enhancement (LGE), extracellular volume (ECV), left ventricular ejection fraction (LVEF), the global and the level (the base, middle, apex) 3D radial strain rate (RS), the circumferential strain rate (CS), the longitudinal strain rate (LS) parameters were collected and statistically analyzed to learn about the differences between the two groups. Results: (1) The scores of right ventricular LGE (χ2=12.10, P＜0.01), atrial LGE (χ2=16.34, P＜0.01), transmural LGE (χ2=12.98, P＜0.01) and query amyloid late enhancement (QALE)(χ2=128.50, P＜0.01) in the ATTR-CA group were wider than those in the AL-CA group, the differences were statistically significant (all P＜0.05), while there was no significant difference in subendocardial LGE between the two groups (χ2=0.07, P=0.79).(2) ECV of basal segment (t=-2.51, P=0.02), middle segment (t=-2.13, P=0.04) and average ECV (t=-2.15, P=0.04) of ATTR-CA group were higher than those of AL-CA group, the differences were statistically significant (all P＜0.05), but there was no significant difference in ECV of apical segment between the two groups (t=-1.47, P=0.15). (3) The global longitudinal strain rate (GLS) (t=2.97, P＜0.01), the basal longitudinal strain rate (BLS) (t=3.43, P＜0.01), the middle longitudinal strain rate (MLS) (U=200.50, P＜0.01), and the apex longitudinal strain rate (ALS) (t=2.38, P=0.02) in the ATTR-CA group were higher than those in AL-CA group, and the differences were statistically significant (all P＜0.05). There was no statistically significant difference between the two groups in the global radial strain rate (GRS) (U=243.50, P=0.06), the basal radial strain rate (BRS) (U=315.00, P=0.53), the middle radial strain rate (MRS) (U= 294.50, P=0.32), and the apex radial strain rate (ARS) (U=254.5, P=0.09). And there also was no statistically significant difference between the two groups in the global circumferential strain rate (GCS) (t=1.45, P=0.15), the basal circumferential strain rate (BCS) (t= 0.52, P =0.60), the middle circumferential strain rate (MCS) (t=1.02, P=0.31), and the apex circumferential strain rate (ACS) (t=1.70, P=0.09). There was no significant statistical difference in relative apical sparing of longitudinal strain (RAS-LS) between the two groups (U=254.5, P=0.09). Conclusions: CMR has certain value in CA typing. The LGE, QALE score and ECV value in the ATTR-CA group were significantly higher than those in the AL-CA group, but the local or global LS of left ventricular was lower than that in the AL-CA group.]]></description>
<pubDate>Mon,20 Sep 2021 00:00:00  GMT</pubDate>
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<title><![CDATA[The stronger sensitivity to missed chances in individuals with IGD: a resting-state fMRI study]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2021.09.008</link>
<description><![CDATA[Objective: By using resting-state functional magnetic resonance imaging (rs-fMRI) technique, the current study investigated the neural mechanisms underlying the processing of missed chances and the response to missed chances in individuals with internet gaming disorder (IGD). Materials and Methods: We recruited 54 IGD participants [age: (22.00±2.27) years] and 53 demographic-matched healthy control (HC) participants [age: (21.89±2.87) years]. After the rs-fMRI scan, participants were asked to perform a sequential risk-taking task, in which they might encounter missed chances. Results: Compared with HC participants, the IGD participants exhibited more risk-taking behaviors (t=3.838, P＜0.01) and were more emotional sensitive to missed chances (t=3.413, P＜0.01). At the neural level, IGD participants showed stronger resting-state functional connectivity (rsFC) between ventral striatum (VS) and superior frontal gyrus (SFG). Additionally, the rsFC between VS and SFG was positively correlated with the emotional sensitivity to missed chances in HC group (r=0.290, P＜0.05). Conclusions: The results indicated that the rsFC between VS and SFG was related to the emotional sensitivity to missed chances, and the emotional and neural responses to missed chances were abnormal in IGD individuals.]]></description>
<pubDate>Mon,20 Sep 2021 00:00:00  GMT</pubDate>
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<title><![CDATA[The effects of repetitive transcranial magnetic stimulation on the left executive control network in heroin dependent individuals: a resting-state fMRI study]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2021.09.009</link>
<description><![CDATA[Objective: To investigate the effect of repetitive transcranial magnetic stimulation (rTMS) on the left executive control network (ECN) in heroin dependent individuals. Materials and Methods: Nineteen heroin dependent individuals (rTMS group) and 22 healthy control subjects (HC group) matched with age, sex and education level were included. The fMRI and behavioral data of the rTMS group were collected before and after treatment, and the fMRI data of the HC group were collected. The differences of cue-induced craving and left ECN before and after treatment in the rTMS group were analyzed. Results: The heroin cue-induced craving score of the rTMS group after treatment (1.47±2.61) was significantly decreased than before treatment (1.82±2.91) (P＜0.05). The abnormally increased functional connectivity between the left dorsolateral prefrontal cortex (DLPFC) and the right DLPFC (MINI coordinate: x=27, y=39, z=51; voxels: 73; corrected by GRF, P＜0.05) was significantly decreased in the rTMS group after treatment with similar tendency toward that of the HC group. Conclusions: It suggested that rTMS can reduce drug cue-induced craving of heroin dependent individuals and help restore abnormal left ECN function of heroin dependent individuals.]]></description>
<pubDate>Mon,20 Sep 2021 00:00:00  GMT</pubDate>
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<title><![CDATA[Brain gray matter volume and functional brain network in patients with lower back pain: a MRI study]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2021.09.010</link>
<description><![CDATA[Objective: To investigate the abnormalities of brain gray matter (GM) and the functional network changes in patients with lower back pain (LBP). Methods and Methods: FMRI was performed on 20 individuals with LBP and 20 age and gender-matched healthy controls (HC). The GM volumes of the two groups were compared by voxel-based morphological (VBM) analysis. In order to reflect the network efficiency, network-based statistics were performed to explore the differences between the brain networks of patients with LBP and those with HC. Results: In comparison of HC, patients with LBP showed reduced GM volumes in several brain cortical areas (P＜0.001). The brain networks in LBP showed a significantly longer characteristic path length as well as a lower clustering coefficient (P＜0.001), global efficiency (P=0.001) and local efficiency (P＜0.001) compared with HC, which led to unstable and inefficient brain networks. In addition, LBP patients showed significantly decreased functional connectivity in several brain areas (P＜0.001). Conclusions: LBP will result in the volume reduction of GM and the damage of the topological properties of the functional brain network. Our results provide a further insight into the neural mechanisms behind LBP.]]></description>
<pubDate>Mon,20 Sep 2021 00:00:00  GMT</pubDate>
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<title><![CDATA[Evalution on the visualization of the extracranial branch of trigeminal nerve using the 3.0 T MR CE 3D-STIR TSE sequence]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2021.09.011</link>
<description><![CDATA[Objective: To investigate the clinical value of contrast-enhanced, three-dimensional spin echo with a short time inversion recovery (CE 3D-STIR-TSE) sequence in the visualization of the anatomical structure of the extracranial branch of the trigeminal nerve. Materials and Methods: Magnetic resonance imaging (MRI) data was collected from a total of 21 healthy individuals (10 male, 11 female), with an average age of (40.78±8.34) years, between July and December 2020. To image the extracranial trigeminal nerve, we utilized the PHILIPS Ingenia 3.0 T MR (CE 3D-STIR-TSE sequence), using gadolinium-diethylenetriamine pentaacetic acid (Gd-DTPA) at a dose of 0.12 mmol/kg as a contrast agent. The original image data was analyzed and evaluated independently by two radiologists, who assigned a score based on how much of the nerve trunk was clearly visible: 4 points for clear display of the complete course of the nerve; 3 points for 50% to 66% of the nerve trunk; 2 points for 33% to 50% of the nerve trunk; 1 point for less than 33% of the nerve trunk; and 0 point if the nerve trunk was not seen. Paired t-test was used to compare the clarity between the left and right branches of the trigeminal nerve for each patient, and a P value＜0.05 was considered a significant difference, in terms of the trigeminal nerve branch clear display rate (4 points cases/total number of cases) and the majority display rate (greater than or equal 3 points cases/total number of cases). Results: The Kappa scores of each branch of the trigeminal nerve in the two groups were＞0.75, with good consistency. Paired t-test comparing the left and right sides of each branch of the trigeminal nerve showed P values＞0.05, with no statistical difference in clarity. The clear and complete display of the ophthalmic meridian, maxillary nerve, auriculotemporal nerve, lingual nerve and inferior alveolar nerve was seen in 80.9%, 76.2%, 80.9%, 90.4%, and 100% of images, respectively. Clear display of 50% to 66% of the same nerves was evident in 90.4%, 85.7%, 90.4%, 95.2%, and 100%, respectively. Conclusions: Our study shows that it is possible to image the anatomy of the extracranial branches of the trigeminal nerve with high accuracy, using the 3.0 T MR CE 3D-STIR TSE sequence.]]></description>
<pubDate>Mon,20 Sep 2021 00:00:00  GMT</pubDate>
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<title><![CDATA[Prediction of Ki-67 expression level in glioblastoma by radiomics model based on T2WI]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2021.09.012</link>
<description><![CDATA[Objective: To explore the value of T2WI imaging model in predicting Ki-67 proliferation level of glioblastoma before operation. Materials and Methods: The preoperative MRI images of 96 patients with glioblastoma diagnosed by pathology in our hospital were retrospectively analyzed. According to the expression level of Ki-67, the patients were divided into two groups: low expression group (Ki-67＜50%) and high expression group (Ki-67≥50). The volume of interest (VOI) was manually sketched on the T2WI axial image and the imaging features were extracted. All cases are divided into training group and test group according to 70%∶30%. The training group was used for feature screening and the establishment of machine learning models. Feature selection was completed by t-test and LASSO. After feature screening, three machine learning models of random forest (RF), Logistic regression and support vector machine (SVM) were established. The test group was used to verify the established model and draw ROC curves, and the results were expressed as accuracy, sensitivity, specificity and AUC. Results: There was no significant difference in age and sex between Ki-67 low expression group and high expression group. Among the three machine learning models, the RF model has the highest diagnostic efficiency, and the accuracy, sensitivity, specificity and AUC are 0.72, 0.67, 0.76 and 0.72 respectively. The comprehensive diagnostic efficiency of the SVM model is the lowest, while the SVM model is between them. Conclusions: The imaging model based on T2WI image has a certain value in predicting the level of Ki-67 expression in glioblastoma before operation, among which RF model is the best.]]></description>
<pubDate>Mon,20 Sep 2021 00:00:00  GMT</pubDate>
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<title><![CDATA[The correlation between diffusion kurtosis imaging and pathological condition in clear cell renal carcinoma]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2021.09.013</link>
<description><![CDATA[Objective: To investigate if the mean diffusivity (MD) and mean kurtosis (MK) allows assessment of pathological condition of clear cell renal cell carcinoma (CCRCC), including microvessel density (MVD), microvessel area (MVA), and Ki-67. Materials and Methods: Thirty-three patients were enrolled in this study, with CCRCC confirmed by surgical pathology. For diffusion kurtosis imaging (DKI), a coronal echo planar imaging (EPI) sequence was performed (repetition time: 4000 ms; echo time: 99 ms; diffusion direction: 3; number of acquisitions: 4; b=0, 800, and 1600 s/mm2; and slice thickness: 4 mm with no intersection gap). MD, MK, MVD, MVA, and Ki-67 were compared between the different nuclear grades. Correlations between MVD, MVA, and Ki-67 and DKI parameters were evaluated. Results: The MDs of low grade and high grade CCRCCs were (2.43±0.11)×10-3 mm2/s and (2.22±0.07)×10-3 mm2/s, respectively. The MK was 0.73±0.03 and 0.82±0.04, respectively. MK were better than MD values in identifying the grade of nuclear grade. A significant difference between high and low grade in MVD, MVA, and Ki-67 was found (t=-8.23, -15.47, and -7.84, respectively, P＜0.05). Significant negative correlations between the MD value and MVD, MVA, and Ki-67 were observed (r= -0.710, -0.746, and -0.733, respectively, P＜0.05). Significant positive correlations between the MK value and MVD, MVA, and Ki-67 were observed (r=0.787, 0.772, and 0.801, respectively, P＜0.05). Conclusions: DKI can be used to noninvasively assess MVD, MVA, and Ki-67 of CCRCC.]]></description>
<pubDate>Mon,20 Sep 2021 00:00:00  GMT</pubDate>
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<title><![CDATA[Diagnostic value of DCE-MRI combined with DWI for central gland prostate cancer]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2021.09.014</link>
<description><![CDATA[Objective: To explore the application value of dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) and diffusion-weighted imaging (DWI) in the diagnosis of central gland prostate cancer (CGPCa). Materials and Methods: The clinical data of 113 patients with prostate diseases confirmed by needle biopsy or surgical pathology in the hospital between January 2017 and January 2020 were retrospectively analyzed. According to the disease type, the patients were divided into CGPCa group (n=51) and benign prostatic hyperplasia group (BPH group, n=62). All patients were subjected to routine MR, DCE-MRI and DWI scanning. The MR images of the two groups were analyzed. The DCE-MRI quantitative parameters and apparent diffusion coefficient (ADC) values were compared between the two groups and between patients with different degrees of CGPCa. The receiver operating characteristic (ROC) curve was used to analyze the diagnostic value of DCE-MRI, DWI and their combination in CGPCa. Results: The volume transfer (Ktrans) and rate constant (Kep) values of CGPCa group were significantly higher than those of BPH group (P＜0.001), and the ADC value was significantly lower than that of BPH group (P＜0.001), but there was no significant difference in the volume fraction (Ve) value between the two groups (P=0.391). In CGPCa group, the Ktrans and Kep values of the low-risk group were significantly lower than those of the middle and high-risk group (P＜0.001), and the ADC value was significantly higher than that of the middle and high-risk group (P＜0.001), but there was no significant difference in the Ve value between the two groups (P=0.249). ROC curve analysis results showed that the area under the curve (AUC) values of Ktrans, Kep, ADC value and their combined diagnosis were 0.732, 0.813, 0.862, and 0.901, respectively (P＜0.001). The sensitivity and specificity of combined diagnosis were higher than those of each index (P＜0.001). Conclusions: Both DCE-MRI and DWI can be used for differential diagnosis of CGPCa. The quantitative parameters Ktrans, Kep value and ADC value of DCE-MRI can provide imaging reference for clinical differential diagnosis of CGPCa, and the combined diagnosis can further improve the diagnostic efficiency.]]></description>
<pubDate>Mon,20 Sep 2021 00:00:00  GMT</pubDate>
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<title><![CDATA[Application value of conventional MRI examination and diffusion weighted imaging in preoperative evaluation of rectal cancer]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2021.09.015</link>
<description><![CDATA[Objective: To analyze the value of conventional MRI and diffusion weighted imaging (DWI) in preoperative evaluation of rectal cancer. Materials and Methods: The data of 42 rectal cancer patients in our hospital were collected retrospectively,all patients underwent pelvic MRI+DWI+enhancement scan before surgery, the T, N stages and circumferential resection margin (CRM) of rectal cancer were evaluated by MRI imaging performance, and the results were compared with the postoperative pathology to evaluate the accuracy of conventional MRI+DWI in the diagnosis of rectal cancer. The application value of DWI in the diagnosis and preoperative evaluation of rectal cancer was explored by measuring the ADC value of the tumor. Results: The results showed good agreement between the preoperative T ,N stages and CRM assessed by conventional MRI+DWI and the postoperative pathological results (Kappa values of 0.745, 0.691 and 0.642, respectively). Comparison of ADC value of rectal cancer with different T stages showed that the higher the T stage with the lower the ADC value, and the difference of ADC value between groups was statistically significant (T1—2 group compared with T3 group: P=0.015;T3 group compared with T4 group: P=0.01). The ADC value of CRM-positive was lower than that of CRM-negative, and the difference was statistically significant (P=0.015). Conclusions: Conventional MRI and DWI imaging have high application value in preoperative staging and CRM evaluation of rectal cancer. The value of ADC has a certain reference value for the diagnosis and preoperative evaluation of rectal cancer.]]></description>
<pubDate>Mon,20 Sep 2021 00:00:00  GMT</pubDate>
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<title><![CDATA[Preliminary study of APT combined with T2 mapping sequence in preoperative risk assessment of endometrial carcinoma]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2021.09.016</link>
<description><![CDATA[Objective: To investigate the value of amide proton metastasis (APT) combined with T2 mapping sequence in preoperative risk assessment of endometrial carcinoma (EC). Materials and Methods: The imaging data of 27 cases of endometrioid adenocarcinoma (among them, there were 10 cases of G1 grade, 11 cases of G2 grade and 6 cases of G3 grade) confirmed by surgery and pathology were retrospectively analyzed. All patients underwent 3.0 T magnetic resonance examination preoperatively, and the scanning sequence included APTw and T2 mapping. Patients were divided into high risk group and low risk group according to pathological type, pathological grade, degree of invasion and other factors. The APTw value of focal APT sequence and the T2 value of T2 mapping sequence were measured respectively by two observers. intraclass correlation coefficient (ICC) was used to test the consistency of measurement results of each parameter value between two observers. According to whether the data conform to normal distribution, independent sample t test or Mann-Whitney U test was used to compare the differences in the values of each parameter, and ROC curve was used to evaluate the efficiency of statistically different parameters in the differential diagnosis of EC in the high and low risk groups. Logistic regression was used to calculate the AUC of APTw combined with T2 mapping to identify EC in the high and low risk groups. DeLong test was used to compare the differences among AUC. Results: The consistency of parameters of lesions measured by two observers was good (ICC＞0.75). The APT value of the high-risk group (2.825%±0.432%) was higher than that of the low-risk group (2.238%±0.314%), and the T2 value of the high-risk group [(77.234±7.722) ms] was lower than that of the low-risk group [(85.870± 13.016) ms], the differences were statistically significant (t=-4.084, 2.164, P＜0.01, 0.040). AUC, sensitivity and specificity of APT value, T2 value and combined diagnosis of high-risk EC were 0.841, 70.0%, 94.1%, 0.674, 90.0%, 52.9%, 0.900, 80.0%, 88.2%, respectively. The P values of the differences between APTw, T2 mapping and combined AUC were 0.2315, 0.2292 and 0.0279, respectively. Conclusions: APT value and T2 value can effectively and quantitatively evaluate the preoperative risk of EC, and it has a good prospect of clinical application.]]></description>
<pubDate>Mon,20 Sep 2021 00:00:00  GMT</pubDate>
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<title><![CDATA[The analysis method of intracranial hypointense disease on T2WI]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2021.09.021</link>
<description><![CDATA[Most of intracranial lesions have hyperintense on T2WI, but part of the intracranial lesions can be characterized hypointense on T2WI, T2WI hypointense is an important imaging features of this kind of disease. On this basis, we give a induction and summary of these diseases, we hope for clinical work to narrow the differential diagnosis, and even can diagnose some diseases. The types of intracranial T2WI hypointense lesions are complex and the pathological basis is different.In this paper, according to the pathology base can be divided into nine categories, including hemoglobin degradation products (deoxyhemoglobin, intracellular methemoglobin hemoglobin and hemosiderin), containing melanin lesions, rich in mucus/protein/cholesterol clefts, rich in cell lesion, mineral deposits, flowing void effect, intracranial pneumatosis, fiber lesions and coagulation necrosis. The clinical lesion manifestations, pathological features and MRI features of the specific diseases under each category were summarized. The clinical features (such as age, sex, clinical manifestations and laboratory examination) and MRI manifestations (including lesion location, morphology, adjacent structure, and peripheral edema, etc.) that have diagnostic and differential diagnostic significance were emphasized. However, it is sometimes difficult to make a definitive diagnosis based on the low signal of T2WI alone. Therefore, the typical features of these diseases in other sequences and enhanced T1WI are also described. Combined with clinical and other MRI sequences, it is helpful for the diagnosis and differential diagnosis of T2WI hypointense lesions. A variety of intracranial lesions may present as T2WI hypointensity, but each of them has its own characteristics. We summarize their imaging findings for diagnosis.]]></description>
<pubDate>Mon,20 Sep 2021 00:00:00  GMT</pubDate>
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<title><![CDATA[Imaging research progress in mild cognitive impairment using convolutional neural networks]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2021.09.022</link>
<description><![CDATA[The Human Connected Group Project is the highest-level research project in the field of brain imaging, and artificial intelligence (AI) is an indispensable tool in the process of brain science research. As one of the latest technologies in the field of AI, convolutional neural networks (CNN) have outstanding performance in computer vision, image processing, etc., and have shown great clinical application prospects in the diagnosis and analysis of mild cognitive impairment (MCI). The author uses CNN as a clue to discuss its current research status and future development direction in the field of MCI.]]></description>
<pubDate>Mon,20 Sep 2021 00:00:00  GMT</pubDate>
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<title><![CDATA[Research progress of arterial spin labeling imaging in early diagnosis and prognosis evaluation of brain injury in premature infants]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2021.09.023</link>
<description><![CDATA[With the continuous development of magnetic resonance imaging technology, arterial spin labeling (ASL) technology could be used to measure and evaluate cerebral blood flow perfusion, and has been gradually applied in clinical practice. ASL technology has the unique advantages of safety and non-invasive, which is suitable for the diagnosis and prognosis evaluation of brain development and injury in premature infants, and provides medical imaging basis for early diagnosis and treatment. Therefore, this article reviews the clinical research status and progress of ASL technology in early diagnosis of common brain injury in premature infants.]]></description>
<pubDate>Mon,20 Sep 2021 00:00:00  GMT</pubDate>
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<title><![CDATA[The research progress of high-resolution magnetic resonance vessel wall imaging in intracranial atherosclerotic plaques]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2021.09.024</link>
<description><![CDATA[High-resolution magnetic resonance vessel wall imaging (HRMR-VWI) is a diagnostic imaging technique used to evaluate and differentiate intracranial vascular lesions. It<sup><sup>,</sup></sup>s detection rate of intracranial atherosclerotic plaques has obvious advantages over traditional imaging methods, and it can effectively display the wall structure and plaque properties, and now it has been widely used in clinical research. Intracranial atherosclerotic plaque is one of the main culprits of ischemic stroke, the detection and evaluation of which is very necessary for the prevention and treatment of ischemic stroke. This paper reviews the imaging features of intracranial atherosclerotic plaque and its relationship with risk factors affecting its stability,brain circulation.]]></description>
<pubDate>Mon,20 Sep 2021 00:00:00  GMT</pubDate>
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<title><![CDATA[Progress of multimodality magnetic resonance imaging in genotyping and prognostic evaluation of gliomas]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2021.09.025</link>
<description><![CDATA[Glioma is the most common intracranial primary tumor in adults, which is prone to recurrence, poor prognosis, and great harm. Genotyping of gliomas is important for the selection of treatment options and prognosis prediction. As the first choice for the diagnosis and evaluation of glioma, magnetic resonance imaging is of great value in reflecting genotyping as well as prognostic evaluation.This article reviews the research progress of multimodality magnetic resonance imaging (MRI) in genotyping and prognostic evaluation of glioma.]]></description>
<pubDate>Mon,20 Sep 2021 00:00:00  GMT</pubDate>
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<title><![CDATA[Application progress of MRI in central nervous system of heat stroke]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2021.09.026</link>
<description><![CDATA[Heat stroke is a fatal emergency, which has a poor prognosis and often causes multiple organ dysfunction including central nervous system. The pathophysiological basis of central nervous system complications of heat stroke includes cerebral hypoperfusion, inflammatory reaction, thrombosis and microbleeds, which lead to different imaging manifestations. Therefore, magnetic resonance imaging (MRI), diffusion weighted imaging (DWI), magnetic resonance venography (MRV), susceptibility weighted imaging (SWI), magnetic resonance spectroscopy (MRS), diffusion tensor imaging (DTI) and diffusion tensor tractography (DTT) have the potential value to provide quantitative and objective evidence for the diagnosis, clinical treatment and prognosis of heat stroke. This article reviews the various MRI techniques used in the central nervous system of heat stroke.]]></description>
<pubDate>Mon,20 Sep 2021 00:00:00  GMT</pubDate>
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<title><![CDATA[Research progress of cardiovascular magnetic resonance in quantitative evaluation of tissue and function of myocardial hypertrophy]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2021.09.027</link>
<description><![CDATA[Cardiovascular magnetic resonance (CMR) has gradually developed into an indispensable tool in cardiology. It is a non-invasive technique, which can objectively evaluate the structure and function of myocardial tissue. In recent years, with the innovation of cardiac magnetic resonance scanning technology and the application of parallel acquisition, T1 mapping and T2 mapping technology can better quantitatively study the characteristics of myocardial tissue. Cardiac diffusion tensor imaging (DTI) can detect the movement direction and amplitude of water molecules in myocardial fibers at microscopic level. The emergence of myocardial strain technology provides a new choice for clinical evaluation of cardiac function. Great progress has been made in computer processing capacity and cloud computing, which effectively promotes the development of CMR artificial intelligence. This review summarizes the new progress of T1 mapping, T2 mapping, DTI, myocardial strain technology and artificial intelligence in quantitative evaluation of tissue and function of myocardial hypertrophy.]]></description>
<pubDate>Mon,20 Sep 2021 00:00:00  GMT</pubDate>
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<title><![CDATA[Progress in imaging assessment of the risk of esophageal varices and bleeding in cirrhosis]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2021.09.028</link>
<description><![CDATA[Esophageal variceal bleeding (EVB) was a fatal complication caused by cirrhosis, and its early prevention had always been a clinical difficulty. Gastroscopy was the gold standard for the diagnosis of esophageal varices (EV) and bleeding in cirrhosis, but it couldn’t widely carried out because of its traumatic nature. At present, some noninvasive detection technologies, which mainly included ultrasound, CT, MRI, and radiomics technology, had become important means of early diagnosis and follow-up of this disease. These noninvasive technologies were expected to replace gastroscopy in the diagnosis of cirrhosic esophageal varices and the assessment of esophageal variceal bleeding risk and provide a new way of thinking. This article will review the recent progress in non-invasive imaging diagnosis and prediction of EV and EVB.]]></description>
<pubDate>Mon,20 Sep 2021 00:00:00  GMT</pubDate>
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<title><![CDATA[Research progress of multimodal MRI in renal cell carcinoma]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2021.09.029</link>
<description><![CDATA[Renal cell carcinoma is one of the most common malignant tumors of urinary system. Its early diagnosis is still a challenging problem in clinical practice. Multimodal magnetic resonance imaging analyses the disease from anatomy and functional imaging, and provides important information for the early imaging diagnosis and the evaluation of therapeutic response of renal cell carcinoma by means of new magnetic resonance imaging technology to improve the prognosis of patients. The purpose of this article is to review the progress of magnetic resonance imaging in renal cell carcinoma.]]></description>
<pubDate>Mon,20 Sep 2021 00:00:00  GMT</pubDate>
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<title><![CDATA[Research progress of chemical exchange saturation transfer imaging technology in musculoskeletal system]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2021.09.030</link>
<description><![CDATA[Chemical exchange saturation transfer imaging (CEST) is a new type of magnetic resonance imaging technology, which can produce semi-quantitative results using the magnetization transfer ratio asymmetry (MTRasym) analysis, which can provide early diagnosis of musculoskeletal system related diseases and surgical decisions are of great significance. Traditional MRI can only reflect the morphological differences of the lesion, and it is difficult to provide help for the early diagnosis of the disease. CEST technology realizes early diagnosis of osteoarthritis (OA), intervertebral discs degeneration, and post operative evaluation of cartilage repair surgery by detecting changes in metabolites in anatomical structures. This technology has the advantages of non-invasive and quantitative detection, and has been widely developed and applied in the central nervous system and musculoskeletal system. This article summarizes the concept, principle, signal measurement and clinical application in the musculoskeletal system of CEST.]]></description>
<pubDate>Mon,20 Sep 2021 00:00:00  GMT</pubDate>
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<title><![CDATA[Research progress in preoperative imaging evaluation of oblique lumbar interbody fusion]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2021.09.031</link>
<description><![CDATA[Oblique lumbar interbody fusion (OLIF) has been widely used in the treatment of lumbar degenerative diseases, and patients have obtained satisfactory results. However, with the development of surgery, various complications have been reported continuously. And imaging is indispensable for OLIF preoperative guidance, extensive review of related papers in recent years, review the studies of imaging in the prevention of complications, such as the size of the surgical window, vascular anatomy, risk assessment of the nerve and ureteral injury, reduce or avoid intraoperative anatomical structure damage, to better guide the surgery.]]></description>
<pubDate>Mon,20 Sep 2021 00:00:00  GMT</pubDate>
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