<?xml version="1.0" encoding="utf-8" ?>
<rss version="2.0">
<channel>
<title>Chinese Journal of Magnetic Resonance Imaging RSS feed</title>
<link>http://med-sci.cn/cgzcx/en/contents_list.asp?issue=202209</link>
<language>zh-cn</language>
<copyright>An RSS feed for Chinese Journal of Magnetic Resonance Imaging</copyright>
<item>
<title><![CDATA[Regional homogeneity changes after MR-guided focused ultrasound thalamotomy in essential tremor: A rs-fMRI study]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2022.09.001</link>
<description><![CDATA[Objective To explore long-term longitudinal changes in local spontaneous brain activity and correlation with clinical tremor scores after MR-guided focused ultrasound (MRgFUS) in essential tremor (ET) patients. Materials and Methods In this study, we included 9 patients with essential tremor who underwent MRgFUS thalamotomy in the Chinese PLA General Hospital from January 2019 to May 2019 and 9 healthy controls with no statistical difference in age and sex, and 9 healthy volunteers with matched age and sex. We collected resting-state functional MRI (rs-fMRI) data and Clinical Rating Scale for Tremor (CRST) at baseline, 6 months and 2 years after MRgFUS thalamotomy in ET patients and rs-fMRI data in healthy volunteers. We used a regional homogeneity (ReHo) approach in the REST plus v1.2 toolkit based on the MATLAB platform, based on whole-brain voxel paired-sample <i>t</i>-tests to identify difference in brain areas in ET patients at baseline and 2 years after MRgFUS thalamotomy, The ReHo values of this significantly different brain region in the HC and ET groups were extracted using the DPABI v5.1 toolkit, a two independent sample <i>t</i>-test was used to compare spontaneous and synchronous brain activity in this significantly different brain region between the HC and ET groups, and one-way repeated measures ANOVA was used to compare spontaneous and synchronous brain activity in this significantly different brain region between the ET group at baseline, 6 months after MRgFUS, and 2 years after MRgFUS. We used Spearman correlation analysis to correlate the trend between clinical tremor improvement in the ET group after surgery and the change in ReHo values in the ET group; and Pearson correlation analysis to correlate the rate of tremor improvement in the ET group 2 years after MRgFUS with the baseline ReHo values in the ET group. Results Findings showed that the significantly different brain regions in the ET group at baseline and 2 years after MRgFUS were located in the right postcentral gyrus. Compared with the HC group, the ReHo value of the right postcentral gyrus at baseline was significantly lower in the ET group (<i>P</i>＜0.01). There was no statistically significant difference in the right postcentral gyrus two years after MRgFUS in the ET group (<i>P</i>＞0.05). The ReHo value of the right postcentral gyrus increased in the ET group at baseline, 6 months after MRgFUS, and 2 years after MRgFUS (<i>F</i>=3.95, <i>P</i>＜0.05). There was a positive correlation between the improvement of clinical tremor and the change of ReHo value after operation; the improvement rate of CRST-A 2 years after MRgFUS in the ET group was negatively correlated with the baseline ReHo value in the ET group (<i>r</i>=-0.709, <i>P</i>=0.032). Conclusions MRgFUS thalamotomy helps relieve tremor symptoms in ET patients, MRgFUS thalamotomy affects the spontaneous and synchronous brain function of ET patients, and there is a correlation between ReHo and clinical score, which provide neuroimaging basis for the evaluation of nerve remodeling after MRgFUS.]]></description>
<pubDate>Tue,20 Sep 2022 00:00:00  GMT</pubDate>
</item>
<item>
<title><![CDATA[Correlation between intracranial volume parameters and cognitive impairment in idiopathic normal pressure hydrocephalus]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2022.09.002</link>
<description><![CDATA[Objective To investigate the correlation between cognitive impairment and intracranial volume parameters in patients with idiopathic normal pressure hydrocephalus (iNPH). Materials and Methods The clinical data were collected from Department of Neurology in Aviation General Hospital from January 2018 to February 2019. Thirty-seven iNPH cases were enrolled. Twenty controls with normal cognitive function matched with the age, gender and educational level of the study group were enrolled from health examination center. All subjects underwent cranial magnetic resonance imaging, Mini Mental State Examination (MMSE), Montreal Cognitive Assessment scale (MoCA). The total intracranial volume, cerebrospinal fluid (CSF) volume, gray matter volume and white matter volume were measured. The relative cerebrospinal fluid volume ratio, gray matter volume ratio and white matter volume ratio were calculated separately. Meanwhile, the Evan<sup><sup>,</sup></sup>s index (EI) and callosal angle (CA) of all subjects were measured. The correlation of cerebrospinal fluid volume ratio, gray matter volume ratio and white matter volume ratio with MMSE and MoCA was analyzed. Results There were no significant differences (<i>P</i>＞0.05) in age and sex between the iNPH group and the control group and there were significant differences (<i>P</i>＜0.05) in EI, CA, gray matter volume ratio, white matter volume ratio and cerebrospinal fluid (CSF) volume ratio. White matter volume ratio was positively correlated with MMSE (<i>r</i>=0.492, <i>P</i>=0.001). The volume ratio of gray matter was negatively correlated with MMSE (<i>r</i>=-0.478, <i>P</i>=0.002). While CSF volume ratio, EI, CA were not correlated with MMSE. There was no correlation between intracranial volume parameters and MoCA. Conclusions The brain white matter volume ratio and gray matter volume ratio are related to cognitive dysfunction in patients with iNPH. The brain white matter volume ratio is negatively related to cognitive dysfunction and the brain gray matter volume ratio is positively related to cognitive dysfunction. When the brain white matter volume ratio is large, the cognitive dysfunction is relatively mild.When the brain gray matter volume ratio is large, the cognitive dysfunction is relatively serious. The measurement of brain white matter volume ratio and gray matter volume ratio can provide objective imaging evidence for the evaluation of cognitive dysfunction in iNPH.]]></description>
<pubDate>Tue,20 Sep 2022 00:00:00  GMT</pubDate>
</item>
<item>
<title><![CDATA[Meta-analysis of local spontaneous brain activity changes in acute and subacute mild traumatic brain injury]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2022.09.003</link>
<description><![CDATA[Objective To explore the most consistent vulnerable regions of mild traumatic brain injury (mTBI) studied by resting state functional magnetic resonance imaging (rs-fMRI), and to reveal the underlying neural mechanism of mTBI. Materials and Methods A search was performed for studies on mTBI resting state brain activation abnormalities by regional homogeneity (ReHo), amplitude of low-frequency fluctuation (ALFF) and fraction amplitude of low-frequency fluctuation (fALFF) before March 2022. The brain regions with abnormal local spontaneous brain activity in mTBI patients compared with healthy subjects in previous studies were summarized, and the signed differential mapping (SDM) software was used for data processing and analysis. Results A total of 11 studies (401 mTBI and 371 healthy controls) were included. Based on meta-analysis, it was confirmed that mTBI patients had significantly increased local spontaneous brain activity in right lingual gyrus, left middle occipital gyrus, right dorsolateral superior frontal gyrus and left central sulcus. Local spontaneous brain activity was decreased in the left anterior cingulate and paracingulate gyrus, right angular gyrus and left middle frontal gyrus (<i>P</i>＜0.005, peak height <i>Z</i>＞1, cluster extent≥20 voxels). Conclusions Meta-analysis was used to confirm the abnormal core brain regions in mTBI patients. These findings help delineate specific areas of interest and understand the neurobiological basis of mTBI.]]></description>
<pubDate>Tue,20 Sep 2022 00:00:00  GMT</pubDate>
</item>
<item>
<title><![CDATA[Value of multi-parameter diffusion weighted imaging in the differential diagnosis of benign and malignant TIC type Ⅱ breast lesions]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2022.09.004</link>
<description><![CDATA[Objective To explore the value of parameters obtained by mono-exponential diffusion-weighted imaging (DWI), intravoxel incoherent motion-DWI (IVIM-DWI) and diffusion kurtosis imaging (DKI) in the differential diagnosis of benign and malignant breast lesions with plateau time-signal-curve (TIC) type-Ⅱ in dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI). Materials and Methods A total of 103 cases with breast TIC type-Ⅱ lesions in the Affiliated Hospital of Jining Medical University from October 2019 to January 2021 were reviewed retrospectively. The patients were divided into benign group (25 patients, 25 lesions) and malignant group (78 patients, 78 lesions) according to the pathological results,the ADC value, true diffusion coefficient (D value), perfusion-related diffusion coefficient (D<sup>*</sup> value), perfusion fraction (f value), mean diffusion rate (MD value) and mean kurtosis value (MK value) were measured. Independent samples <i>t</i>-test was used to compare the differences of each parameter between the two groups, and univariate/multivariate logistic regression analyses were further performed. Receiver operating characteristic (ROC) curve and area under the curve (AUC) were used to analyze the diagnostic efficacy of each parameter alone or combination diffusion models (DWI+IVIM, DWI+DKI and DWI+IVIM+DKI) in differentiating benign and malignant breast TIC type-Ⅱ lesions. Results The ADC, D, f, MD, and MK values of the two groups were significantly different (<i>P</i>＜0.05), but the D<sup>*</sup> value of the two groups had no significant difference (<i>P</i>＞0.05). Multiple logistic regression analysis showed that the D value and MK value were independent influencing factors in the differential diagnosis of the two groups, with the largest odds ratio for MK value (AUC 0.871, specificity 88.0%, sensitivity 80.8% and accuracy 78.6%). There was no significant difference in AUC among each combined diffusion model (<i>P</i>＞0.05), but three-combination diffusion model achieved the greatest diagnostic efficiency (AUC 0.915, sensitivity 92.3%, specificity 84.0% and accuracy 86.4%), and the AUC of which was statistically higher than that of DWI (AUC 0.816, <i>P</i>＜0.05). Conclusions DWI combined with IVIM and DKI have a good differential diagnostic value for benign and malignant breast TIC type-Ⅱ lesions.]]></description>
<pubDate>Tue,20 Sep 2022 00:00:00  GMT</pubDate>
</item>
<item>
<title><![CDATA[Comparative assessment of MRI BI-RADS 4 breast lesions with Kaiser score and apparent diffusion coefficient value]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2022.09.005</link>
<description><![CDATA[Objective To investigate the diagnostic performance of the Kaiser score and apparent diffusion coefficient (ADC) to Breast Imaging Reporting and Data System (BI-RADS) Category 4 lesions at dynamic contrast-enhanced MRI (DCE-MRI). Materials and Methods The cases who underwent breast MRI and were classified as BI-RADS category 4 with clear pathological findings in Hebei General Hospital from June 2020 to February 2022 were retrospectively analyzed. The measurement of ADC value was designated by experienced physicians to designate a region of interest (ROI) and measured. Using logistic regression combined Kaiser score and ADC value to obtain the predictor Kaiser+. Receiver operating characteristic (ROC) curve analysis was performed to evaluate the diagnostic performance of Kaiser score, Kaiser+ and ADC. The area under the curve (AUC) values were calculated and compared by using the Delong test. Results The study involved 128 women with 165 lesions. Overall diagnostic performance for Kaiser score (AUC=0.882) was significantly higher than for ADC (AUC=0.582; <i>P</i>＜0.05). There were no significant differences in AUCs between Kaiser score and Kaiser+ (<i>P</i>=0.885). Compared with ADC value, the Kaiser score is independent of background parenchymal enhancement when making a lesion diagnosis. Conclusions For BI-RADS 4 breast lesions, the Kaiser score is superior to ADC mapping and may help to avoid unnecessary biopsies. However, the combination of both indicators did not significantly contribute to breast cancer diagnosis.]]></description>
<pubDate>Tue,20 Sep 2022 00:00:00  GMT</pubDate>
</item>
<item>
<title><![CDATA[The value of 3D convolution neural network based on multimodal MRI images in the classification of liver fibrosis]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2022.09.006</link>
<description><![CDATA[Objective To construct a 3D convolution neural network (CNN) model of multi-modal MRI images, and verify its value in classification of liver fibrosis (LF). Materials and Methods Two hundred and twenty four cases with LF confirmed by pathology were retrospectively collected. All patients underwent 3.0 T MRI exams. Collected the T1WI, T2WI, and apparent diffusion coefficient (ADC) images and randomly divided them into training group and testing group according to the ratio of 8∶2. After the images were preprocessed, the images of training group were used to iteratively train the network structure of the model. And then a 3D-CNN model was established to distinguish between no-significant LF (S0-S1) and significant LF (≥S2). The 3D-CNN model was composed of three convolution layers, three pooling layers and two fully connected layers. The accuracy (ACC), loss function curves and receiver operating characteristic (ROC) curves acquired by using the testing dataset were used to evaluate the performance of the 3D-CNN model. Results The area under the curve (AUC) value of 3D-CNN model based on multiparametric MRI for LF classification was 0.94 in the training group and 0.98 in the testing group. Conclusions The multiparametric 3D-CNN deep learning model may be an effective method, which can distinguish between no-significant and significant LF. It provides more options for non-invasive assessment of LF.]]></description>
<pubDate>Tue,20 Sep 2022 00:00:00  GMT</pubDate>
</item>
<item>
<title><![CDATA[Correlation between Gd-EOB-DTPA enhanced MRI T1 mapping and Ki-67 expression in hepatocellular carcinoma]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2022.09.007</link>
<description><![CDATA[Objective To investigate the correlation between gadolinium-ethoxybenzyl-diethylenetriamine pentaacetic acid (Gd-EOB-DTPA) enhanced MRI T1 mapping and Ki-67 expression in hepatocellular carcinoma (HCC). Materials and Methods The data of 74 patients diagnosed with HCC in Shunde Hospital, Southern Medical University (the First People<sup><sup>,</sup></sup>s Hospital of Shunde) from July 2019 to December 2020 were retrospectively collected, and multiphase enhanced MRI scans with Gd-EOB-DTPA were performed before surgery, including pre-enhancement (Pre), arterial phase (AP), portal venous phase (PP), equilibrium phase (EP), hepatobiliary phase (HBP), T1 mapping, while Ki-67 staining was performed. Quantitative parameters including T1 relaxation time (T1rt), reduction rate of T1 relaxation time (rrT1rt), tumor to liver contrast ratio (TLR), contrast enhancement ratio (CER) were measured. The correlations between each quantitative parameter and the expression of pathological Ki-67 were analyzed using Spearman correlation coefficient. In addition, patients were divided into low Ki-67 expression group (≤25%, 40 cases) and high Ki-67 expression group (＞25%, 34 cases), and the differences of quantitative parameters between the two groups were compared by independent samples <i>t</i> test or Mann-Whitney <i>U</i> test. The diagnostic efficacy of each parameter was analyzed according to the receiver operating characteristic curve, and the difference of the area under the curve (AUC) of each parameter was compared by DeLong test (<i>P</i>＜0.05). Results T1rt-Pre, T1rt-20min are strongly positively correlated with Ki-67 [<i>r</i>=0.668 (95% <i>CI</i>: 0.515-0.780),<i>r</i>=0.659 (95%<i> CI</i>: 0.494-0.784),all <i>P</i>＜0.001]; TLR-Pre, TLR-HBP are moderately negatively correlated with Ki-67 [<i>r</i>=-0.495 (95%<i> CI</i>: -0.647--0.300), <i>r</i>=-0.497 (95%<i> CI</i>: -0.670--0.288), all <i>P</i>＜0.001]; TLR-PP, TLR-EP was weakly negatively correlated with Ki-67 [<i>r</i>=-0.272 (95%<i> CI</i>: -0.483--0.035)<i>, P</i>=0.019; <i>r</i>=-0.362 (95%<i> CI</i>: -0.568--0.142), <i>P</i>=0.002]. There were significant differences in T1rt-Pre, T1rt-20min, TLR-Pre, TLR-AP, TLR-EP, TLR-HBP between the two groups (all <i>P</i>＜0.05). The AUC of T1rt-Pre, T1rt-20min, TLR-Pre, TLR-AP, TLR-EP, TLR-HBP were 0.868 (95%<i> CI</i>: 0.769-0.936); 0.890 (95%<i> CI</i>: 0.795-0.951); 0.717 (95%<i> CI</i>: 0.670-0.869); 0.646 (95%<i> CI</i>: 0.527-0.754); 0.680 (95%<i> CI</i>: 0.561-0.784); 0.782 (95%<i> CI</i>: 0.670-0.869), respectively. The AUC values of T1rt-Pre and T1rt-20min were significantly different from those of TLR-Pre, TLR-AP and TLR-EP respectively (all <i>P</i>＜0.05), but had no statistical difference with TLR-HBP. Conclusions T1rt-Pre, T1rt-20min on Gd-EOB-DTPA enhanced MRI combined with T1 mapping were strong positive correlation with the expression of Ki-67 in HCC, and T1rt-Pre and T1rt-20min has a high evaluation value for the expression of Ki-67 in HCC.]]></description>
<pubDate>Tue,20 Sep 2022 00:00:00  GMT</pubDate>
</item>
<item>
<title><![CDATA[The investigation of association between radiologic extranodal extension and pathological grades of prostate cancer]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2022.09.008</link>
<description><![CDATA[Objective To investigate the correlation between radiologic extranodal extension (rENE) and prostate cancer Gleason score and International Society of Urological Pathology (ISUP) grades. Materials and Methods Ninety PCa N1 cases with integrated MRI and pathology data in Xijing Hospital affiliated to Air Force Medical University from January 2017 to June 2021 were selected. According to the presence or absence of rENE, they were divided into rENE+ and rENE- groups, of which 67 cases were in the rENE+ group and 23 cases in the rENE‍- group. The statistical differences between groups were analyzed using the Wilcoxon test. The correlation between rENE and Gleason scores, ISUP grades were evaluated by Spearman<sup><sup>,</sup></sup>s rank correlation coefficient. Relative risk (RR) rate of ISUP grades was also calculated. Results The Gleason scores and ISUP grades in rENE+ patients were higher than rENE- patients, the statistical differences between two groups were significant. Patients in the rENE+ group were 2.6 times more likely to have ISUP 5 than those in the rENE- group (RR=2.6, 95% <i>CI</i>: 1.477-3.676) and patients in the rENE- group were 17.4 times more likely to have ISUP≤3 than those in the rENE+ group (RR=17.4, 95% <i>CI</i>: 4.2-72.3). The Spearman<sup><sup>,</sup></sup>s rank correlation coefficient was 0.547 (95%<i> CI</i>: 0.363-0.688), 0.570 (95% <i>CI</i>: 0.367-0.716) in Gleason scores and ISUP grades. Conclusion rENE was moderately related to Gleason scores and ISUP grades. Compared to rENE- patients, rENE+ patients got higher Gleason scores and ISUP grades. rENE may be used to predict the degree of malignancy of PCa noninvasively.]]></description>
<pubDate>Tue,20 Sep 2022 00:00:00  GMT</pubDate>
</item>
<item>
<title><![CDATA[Value of amide proton transfer imaging and intravoxel incoherent motion imaging in estimating histologic grades of endometrial adenocarcinoma]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2022.09.009</link>
<description><![CDATA[Objective To investigate the effect of amide proton transfer (APT) imaging and intravoxel incoherent motion (IVIM) imaging in estimating histologic grades of endometrial adenocarcinoma (EA). Materials and Methods A total of 39 patients with pathologically confirmation of EA underwent pelvic magnetic resonance imaging (grade Ⅰ, <i>n</i>=16; grade Ⅱ, <i>n</i>=14; grade Ⅲ, <i>n</i>=9), including APT and IVIM sequences. APT values and IVIM-derived parameters (f, D, D<sup>*</sup>) of lesions were calculated respectively by two radiologists. We used a Shapiro-Wilk test to evaluate whether the APT values and IVIM-derived parameters were normally distributed. The intraclass correlation coefficient (ICC) was calculated to describe the correlations of the measurements of each parameter between two readers. The differences of APT values and IVIM-derived parameters were calculated and compared among three grades. Then the receiver operating characteristic (ROC) curves and DeLong test were used to evaluate the efficiency of the parameters with statistically differences. Spearman<sup><sup>,</sup></sup>s correlation analysis was also used between APT values and histologic grades, between IVIM-derived parameters and histologic grades, and between APT values and IVIM-derived parameters. Results All parameters in our research were normally distributed. The ICC of APT values and IVIM-derived parameters between the two readers showed excellent interobserver agreements (APT: 0.955; f: 0.958; D: 0.964; D<sup>*</sup>: 0.825). The APT values for grade Ⅱ and grade Ⅲ (3.17%±0.43%, 3.45%±0.42%) were significantly higher than grade Ⅰ (2.66%±0.63%), with statistically significant differences (<i>P</i>=0.012, <i>P</i>=0.001). The f values for grade Ⅱ and grade Ⅲ (0.170%±0.049%, 0.150%±0.011%) were significantly lower than grade Ⅰ (0.220%±0.080%), with statistically significant differences (<i>P</i>=0.027, <i>P</i>=0.010). The ROC analysis showed the AUC (area under the curve) of the APT values, f values and the combined diagnosis of both were as follows: grade Ⅰ vs. grade Ⅱ: 0.78, 0.70, 0.83; grade Ⅰ vs. grade Ⅲ: 0.86, 0.81, 0.92. There were no significant differences in AUC comparison among APT values, f values and combined diagnosis of both. APT values showed a positive correlation with histologic grades (<i>r</i><sub>s</sub>=0.578, <i>P</i>＜0.001) while f values showed a negative correlation (<i>r</i><sub>s</sub>=-0.416, <i>P</i>=0.008). Conclusions APT values and f values were correlated with the histologic grades of EA, and there was no significant difference of APT values and f values in differentiating the histologic grades of EA. APT and IVIM imaging may be helpful to predict histologic grades of EA.]]></description>
<pubDate>Tue,20 Sep 2022 00:00:00  GMT</pubDate>
</item>
<item>
<title><![CDATA[Magnetic resonance image compilation in the assessment of chronic supraspinatus tendinitis]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2022.09.010</link>
<description><![CDATA[Objective To investigate the diagnostic value of quantitative parameters of magnetic resonance image compilation (Magic) sequence on chronic supraspinatus tendinitis. Materials and Methods Forty-two patients with clinical suspicion of supraspinatus tendinitis (tendinitis group) and 28 healthy volunteers (control group) were prospectively collected. Conventional anatomical imaging sequences T2WI fat saturation (FS) sequence and T1WI FS sequence in axial view, T1W FS sequence in oblique coronal view, proton density weighted (PDW) sequence in oblique sagittal view and Magic sequence in oblique coronal view were performed with SIGNA<sup>TM</sup> Architect 3.0 T scanner. The supraspinatus tendon was divided into lateral, medial and middle subregions according to its shape in oblique coronal T2WI images view on Magic sequence. Two radiologists with 10 years of experience in musculoskeletal system diagnosis measured the T1, T2 and proton density (PD) values of the supraspinatus tendon on the Magic oblique coronal images, interclass correlation coefficient (ICC) were used to compared the consistency between and within observers. One-way analysis of variance or Kruskal-Wallis <i>H</i> test were used to compare the differences of quantitative parameters in different regions. Receiver operating characteristic (ROC) curves were drawn for parameters with statistically significant differences to evaluate the diagnostic efficacy for tendinitis. Results The T1 and T2 value in the lateral subregion, T2 value in the middle subregion of the tendinitis group were higher than those in the control group, and the difference was statistically significant (<i>P</i>＜0.05). The PD values in lateral subregion, T1 values and PD values in the middle subregion had no significant difference between the two groups (<i>P</i>＞0.05). The T1, T2 and PD value in the medial subregion had no significant difference between the two groups (<i>P</i>＞0.05). The AUC of T1 value in the lateral subregion for the diagnosis of supraspinatus tendinitis was 0.821, sensitivity and specificity were 90.5% and 67.9%. The AUC of T2 value in the lateral subregion was 0.733, sensitivity and specificity were 66.7% and 78.6%. The AUC of T2 value in the middle subregion was 0.682, sensitivity and specificity were 61.9% and 75.0%. The above three values had high diagnostic efficacy for supraspinatus tendinitis. Conclusions The T1 and T2 values of Magic sequence are effective quantitative parameters reflecting chronic supraspinatus tendinitis, which can provide quantitative objective basis of supraspinatus tendinitis.]]></description>
<pubDate>Tue,20 Sep 2022 00:00:00  GMT</pubDate>
</item>
<item>
<title><![CDATA[Identification of triangular fibrocartilage complex injury based on MRI radiomics model]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2022.09.011</link>
<description><![CDATA[Objective To develop a MRI-based radiomics model to evaluate the diagnostic efficiency of the injury of triangular fibrocartilage complex (TFCC). Materials and Methods In this retrospective study, 100 cases (injury/non-injury: 50/50) were enrolled from China-Japan Union Hospital of Jilin University within January 2019 to December 2021. All patients had high resolution 3.0 T MRI examination of the wrist. Radiomics features of each patient were extracted from T2-weighted coronal imaging by manual segmentation. The Mann-Whitney <i>U</i> test and least absolute shrinkage and selection operator (LASSO) algorithm were used to eliminate irrelevant and redundant features, to additionally choose the significant features. The most significant parameters were used to build the prediction model by support vector machine (SVM) classifier. Predictive performance of the model was validated using the area under  the receiver operating characteristics (ROC) curve (AUC), accuracy, sensitivity and specificity. Results A total of 88 initial radiomics features were extracted from each image. Twelve relevant radiomic features were selected based on the Mann-Whitney <i>U</i> test and LASSO algorithm. The classifier constructed with SVM achieved an AUC of 0.88 based on the most significant features, the accuracy, sensitivity and specificity were 90%, 92% and 100% respectively. The radiomics model exhibited good performance in predicting the injury of TFCC. Conclusions The MRI-based radiomics model could provide a non-invasive tool to identify the injury of TFCC and improve the detection rate of it.]]></description>
<pubDate>Tue,20 Sep 2022 00:00:00  GMT</pubDate>
</item>
<item>
<title><![CDATA[Quantitative assessment of bone marrow fat fraction of proximal femur in healthy subjects based on MRI mDIXON‐Quant technique]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2022.09.012</link>
<description><![CDATA[Objective The proton density fat fraction (PDFF) of bone marrow was obtained by MRI mDIXON‐Quant sequence. The change trend of bone marrow fat content in the proximal femur of healthy subjects was observed, and the effects of age, gender and body mass index (BMI) on bone marrow fat content were detected. Materials and Methods From June 2021 to March 2022, a total of 227 patients aged 20-80 years were recruited for routine MRI examination and mDIXON-Quant examination of the proximal femur. The inclusion criteria and the image quality were satisfactory, with age of (53.59±14.20) years. The PDFF values of femoral head, femoral neck, greater trochanter and intertrochanter were obtained. Mann-Whitney <i>U</i> test was used to compare the difference of bone marrow PDFF values in different age groups and genders, and Kruskal-Wallis test was used to compare the bone marrow PDFF values in different regions. The Spearman correlation test was used to analyze correlations between age, gender, BMI and bone marrow PDFF, respectively. Finally, multiple linear regression analysis was performed on the PDFF values of each region of proximal femur with age, gender and BMI. Results The PDFF value of bone marrow in young and middle-aged subjects was lower than that in old subjects, and the PDFF value of each subregion was positively correlated with age (<i>P</i>＜0.05). The bone marrow PDFF of males was higher than that of females in all of subregions (<i>P</i>＜0.05). There were significant differences in PDFF between the subregions (<i>P</i>＜0.05). The bone marrow PDFF of the greater trochanter was the highest. The femoral neck PDFF was the lowest. Conclusions The bone marrow fat content in proximal femur increased with age. The amount of bone marrow fat content in the proximal femur may be higher in men than in women. The content of bone marrow fat was different between subregions of proximal femur.]]></description>
<pubDate>Tue,20 Sep 2022 00:00:00  GMT</pubDate>
</item>
<item>
<title><![CDATA[Experimental study on the evaluation of acute mesenteric artery ischemia in the small intestine wall injury of rabbits by quantitative magnetic resonance T2‐mapping technique]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2022.09.013</link>
<description><![CDATA[Objective To explore the diagnostic value of T2‐mapping in quantitatively monitoring and assessing dynamic small intestine wall injury after acute mesenteric artery ischemia (AMI) in a rabbit model by MRI. Materials and Methods Thirty-six New Zealand white rabbits were randomly divided into two groups. The experimental group performed surgical ligation of the arc-shaped vascular network of the 2nd-5th mesenteric artery and the blood supply vessels at both ends of the corresponding intestinal tract, followed by MR T2‐mapping imaging at 6 time points (1 h, 2 h, 3 h, 4 h, 5 h, 6 h), 3 rabbits at each time point. After scanning, 3 rabbits were euthanized, and the intestinal pathological specimens supplied by the third branch of the mesenteric artery arc vascular network were taken out to evaluate the severity of ischemic damage to the small intestinal wall and the changes in pathological characteristics. The control group underwent sham operation without ligation. The differences between the quantitative values of the experimental group and the control group at each time point were performed by independent samples <i>t</i> test, and the intra-group comparison of T2 values at each time point between the two groups was performed by one-way analysis of variance. A Gaussian fitting model was used to fit the T2 value to the ischemic time point to show the evolution of the ischemic intestinal wall in the small intestine, which was verified by histopathology. The fitting equation between T2 value and ischemic time point is f(<i>x</i>)=145×exp{-[(<i>x</i>-3.475)/4.297]<sup>2</sup>}, and the fitting coefficient R<sup>2</sup>=0.79. Results The T2 values of the experimental group at 6 time points were higher than those of the control group, and the difference was statistically significant (<i>P</i>＜0.05). There were statistical differences between T2<sub>3h</sub> and T2<sub>1h</sub>, T2<sub>2h</sub>, T2<sub>5h</sub> and T2<sub>6h</sub> in the experimental group (<i>P</i>＜0.05). With the progression of ischemia time, the T2 value first increased and then decreased. The pathological manifestations in the first 3 hours were mainly edema and infiltration of inflammatory cells. The T2<sub>3h</sub> value reached a peak value of (151.50±2.90) ms at nearly 3 hours of ischemia on the image; at 4 h of ischemia, the intestinal wall injury reached the muscle layer, and the bleeding area greatly increased, the T2<sub>4h</sub> value decreased to (142.50±4.30) ms, and the T2 value continued to decrease thereafter. Conclusions MRI T2-mapping technology helps to quantitatively evaluate the small intestinal wall damage in AMI, has certain advantages for early detection of the disease, and has a good clinical application prospect.]]></description>
<pubDate>Tue,20 Sep 2022 00:00:00  GMT</pubDate>
</item>
<item>
<title><![CDATA[Application of multi-shot echo planar imaging diffusion weighted imaging in the skull base]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2022.09.014</link>
<description><![CDATA[Objective To explore the performance of image reconstruction using image-space sampling (IRIS)-based multi-shot echo planar imaging diffusion weighted imaging (MS-EPI DWI) for the skull base region. Materials and Methods Forty-nine volunteerss were recruited, with an average age of (42.00±19.39) years old. All subjects underwent conventional single-shot echo planar imaging diffusion weighted imaging (SS-EPI DWI) and IRIS-based multiple-shot diffusion-weighted imaging (8, 6, 4, and 2 shots, respectively). The apparent diffusion coefficient (ADC) values, signal to noise ratio (SNR) and contrast to noise ratio (CNR) of bilateral cerebellum, brainstem and pons were measured or calculated. A five-point scoring method was used by two observers to subjectively evaluate the image quality. The Kappa test was adopted to evaluate the consistency of the scores by the two observers. The differences of ADC, SNR, CNR and subjective scores among MS-EPI DWI with different number of shots and SS-EPI DWI were analyzed using Friedman test. If the differences were statistically significant, subsequent multiple comparisons were performed with Bonferroni correction for <i>P</i> values. Results The scores by the two observers were in good agreement (Kappa=0.795, 0.871, 0.782, 0.880, 0.847). Compared with different shot times of MS-EPI DWI, there was no significant difference in ADC between the two sides of the cerebellum, and there was statistical difference in the rest of the data (<i>P</i>＜0.05). Compared with the SS-EPI DWI sequence, when the number of shots was 8, the ADC in the left brainstem and pons was smaller than that in the SS-EPI DWI (<i>P</i>＜0.05), and when the number of shots was 4 and 2, the ADC in the bilateral brainstem and pons was smaller than that in the SS-EPI DWI (<i>P</i>＜0.05). When the number of shots was 8, 6, and 2, the SNR, CNR and subjective scores of both sides of the cerebellum and pons and brain stem of MS-EPI DWI were higher than those of SS-EPI DWI. When the number of shots was 6, the SNR and CNR of the left cerebellum and pontine stem, the SNR and CNR of the right cerebellum, the SNR of the right pontine stem and subjective scores were significantly different from those of SS-EPI DWI (<i>P</i>＜0.05). Conclusions Compared with SS-EPI DWI, MS-EPI DWI based on IRIS that showed higher SNR and lower geometric distortion compared with SS-EPI DWI. MS-EPI DWI shots 6 is recommended for clinical skull base between imaging time and image quality.]]></description>
<pubDate>Tue,20 Sep 2022 00:00:00  GMT</pubDate>
</item>
<item>
<title><![CDATA[The value of diffusion kurtosis imaging in the early diagnosis of Parkinson<sup><sup>,</sup></sup>s disease]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2022.09.015</link>
<description><![CDATA[Objective To explore the value of diffusion kurtosis imaging (DKI) in the early diagnosis of Parkinson<sup><sup>,</sup></sup>s disease (PD). Materials and Methods Fifty patients with PD diagnosed by PD specialty in our hospital from January 2018 to June 2021 were randomly selected as PD group, and 50 healthy people who came to our hospital for physical examination at the same time were selected as healthy control (HC) group. The mean kurtosis (MK) value, axial kurtosis (Ka) value, radial kurtosis (Kr) value, mean diffusivity (MD) value, axial diffusivity (Da) value, radial diffusivity (Dr) value and fractional anisotropy (FA) value of brain nuclei DKI parameters in PD group and HC group were compared, and the correlation with Mini-mental State Examination (MMSE) score was compared. Results Except the Ka value of the red nucleus, the Kr value of the thalamus, putamen and globus pallidus, the other DKI parameters of the red nucleus, substantia nigra, thalamus, putamen, globus pallidus and caudate nucleus among the DKI parameters of the two groups were significantly different (<i>P</i>＜0.05). The area under the curve (AUC) of the MK value of the red nucleus and substantia nigra in PD patients is the largest, followed by the MD value of substantia nigra, Ka value of substantia nigra, Dr value of substantia nigra and MK value of red nucleus according to the area under the curve (AUC). The AUC were 1.000, 0.992, 0.818, 0.808 and 0.791, respectively. The correlation analysis between DKI parameters and MMSE score showed that MK value of substantia nigra (<i>r</i>=0.572, <i>P</i>=0.043) and MD value (<i>r</i>=0.827, <i>P</i>=0.039), MK value of red nucleus (<i>r</i>=0.738, <i>P</i>=0.042) and MD value (<i>r</i>=0.899, <i>P</i>=0.031) are positively correlated with MMSE score, and there was no significant correlation between other DKI parameters and MMSE score. Conclusions The DKI can be used in the diagnosis of PD, and the parameters of substantia nigra DKI can be used as a priority index for the differential diagnosis of PD and guiding the severity of PD.]]></description>
<pubDate>Tue,20 Sep 2022 00:00:00  GMT</pubDate>
</item>
<item>
<title><![CDATA[Value of diffusion-weighted imaging combined with diffusion kurtosis imaging in the hierarchical diagnosis and prognosis assessment of glioma]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2022.09.016</link>
<description><![CDATA[Objective To investigate the value of diffusion-weighted imaging (DWI) combined with diffusion kurtosis imaging (DKI) in the hierarchical diagnosis and prognosis assessment of glioma. Materials and Methods A total of 82 cases with glioma who were admitted to our hospital from February 2017 to February 2019 were retrospectively analyzed, and all of them underwent DWI and DKI before surgery. The conventional MRI scan characteristics, DWI and DKI parameters, including apparent diffusion coefficient (ADC), mean kurtosis (MK), axial kurtosis (Ka), radial kurtosis (Kr), mean diffusivity (MD) and fractional anisotropy (FA) of patients with different grades of glioma were compared. The patients were followed up until October 2021. According to the prognosis, the patients were divided into the survival group and the death group, and the prognosis were analyzed by univariate analysis and multivariate logistic regression analysis. The receiver operating characteristic (ROC) curve of DWI and DKI parameters predicting prognosis were drawn. Results Among the 82 glioma patients, 38 were low-grade (5 cases of grade 1, 33 cases of grade 2), and 44 were high grade (21 cases of grade 3, 23 cases of grade 4). There was no significant difference in the number of lesions, signal, lesion area, edema and enhancement in different grades of gliomas (<i>P</i>＞0.05). With the increase of glioma grade, ADC and MD decreased, while MK, Ka, Kr increased (all <i>P</i>＜0.05); the glioma grade was significantly negatively correlated with ADC and MD, and significantly positively correlated with Ka and Kr (all <i>P</i>＜0.05). As of October 2021, 40 cases of the 82 glioma patients survived and 42 cases died. In the death group, the proportion of high-grade glioma, multiple lesions, obvious edema, and obvious enhancement, as well as MK, Ka, and Kr, were higher than those in the survival group, and ADC was lower than that in the survival group (<i>P</i>＜0.05). Multivariate logistic regression analysis showed that glioma grade, peritumoral edema, tumor enhancement, ADC, and MK were prognostic factors (<i>P</i>＜0.05). The area under the curve of MK for predicting the prognosis of glioma patients was 0.835 (95% <i>CI</i>: 0.690-0.961), and the sensitivity and specificity were 86.6% and 80.5% when 0.550 was used as the cut-off value; the area under the curve of ADC predicting the prognosis was 0.789 (95% <i>CI</i>: 0.633-0.945), the sensitivity and specificity were 82.9% and 76.8% when the cut-off value was 1.240; the area under the curve of MK combined with ADC for predicting prognosis was 0.903 (95% <i>CI</i>: 0.808-0.994), the sensitivity and specificity were 93.9% and 85.4%. Conclusions The DWI combined DKI can non-invasively evaluate the proliferation activity and water molecule diffusion information of glioma cells, and has a high evaluation value for the grading diagnosis and prognosis evaluation of glioma. The combination of MK and ADC can effectively predict the prognosis of glioma patients.]]></description>
<pubDate>Tue,20 Sep 2022 00:00:00  GMT</pubDate>
</item>
<item>
<title><![CDATA[Tumor regression grade after neoadjuvant chemoradiotherapy for locally advanced rectal cancer: MRI and pathological control study]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2022.09.017</link>
<description><![CDATA[Objective To investigate the diagnostic efficacy of magnetic resonance tumor regression grade (mrTRG) and affecting factors. Materials and Methods A retrospective study was conducted in 129 cases with locally advanced low rectal cancer admitted to the Anorectal Disease Diagnosis and Treatment Center of Tianjin Union Medical Center from October 2017 to June 2021. All patients received conventional long-term concurrent chemoradiotherapy and radical surgery. MRI scans were performed 1 week before and 4 weeks after the end of concurrent chemoradiotherapy. Using pathologic tumor regression grade (pTRG) as the gold standard, Kappa test was used to analyze the diagnostic efficacy of mrTRG. The effects of different MR factors [diffusion-weighted imaging (DWI), T staging, high signal intensity on T2WI, mesorectal fascia invasion positive (MRF+), extramural vascular invasion positive (EMVI+)] on the diagnostic efficacy of mrTRG were evaluated by stratified analysis. Results Using T2WI alone, 57 cases were mrTRG 1-2 and 72 cases were mrTRG 3-5. Using T2WI combined with DWI, 70 cases were mrTRG 1-2 and 59 cases were mrTRG 3-5. The pathological results showed that 66 cases were pTRG 0-1 and 63 cases were pTRG 2-3. mrTRG was moderately consistent with pTRG (T2WI alone: Kappa=0.602, <i>P</i>＜0.001; T2WI+DWI: Kappa=0.693, <i>P</i>＜0.001). Compared with T2WI, T2WI combined with DWI increased the sensitivity (86.4% vs. 82.9%), specificity (83.9% vs. 77.1%), negative predictive value (89.7% vs. 79.4%), Jorden index (70.3% vs. 60.0%) and total coincidence rate (84.9% vs. 80.2%) of mrTRG. High T stage, T2WI high signal intensity, MRF+ and EMVI+ reduced the sensitivity, specificity, positive predictive value, negative predictive value, Jordon index and total coincidence rate of mrTRG in varying degrees (except the effect of high T2WI signal on mrTRG sensitivity). Conclusions T2WI combined with DWI can improve the diagnostic efficiency of mrTRG. High T stage, T2WI high signal intensity, MRF+, EMVI+ before neoadjuvant chemoradiotherapy will reduce the accuracy of mrTRG assessment.]]></description>
<pubDate>Tue,20 Sep 2022 00:00:00  GMT</pubDate>
</item>
<item>
<title><![CDATA[Difference of MRI characteristics and HIFU related parameters of four subtypes of adenomyosis]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2022.09.018</link>
<description><![CDATA[Objective To explore the differences of MRI characteristics and relevant parameters of high intensity focused ultrasound therapy of the four subtypes of adenomyosis based on magnetic. Materials and Methods A tatal of 203 cases with adenomyosis treated by high intensity focused ultrasound (HIFU) were retrospectively analyzed. According to the location relationship between the adenomyosis focus, the uterine junction zone and the endometrium shown by T2 weighted imaging (T2WI), the adenomyosis was divided into 43 cases of type Ⅰ (intrinsic), 48 cases of type Ⅱ (extrinsic), 29 cases of type Ⅲ (intrinsic) and 83 cases of type Ⅳ (intrinsic). The clinical data, preoperative MRI characteristics and postoperative treatment parameters of different subtypes were compared. Results The energy efficiency factor (EEF) of the four subtypes were 2.02, 3.18, 1.88, and 3.50 J/mm<sup>3</sup> respectively. The nonperfused volume ration (NPVR) of the four subtypes were 47.78%, 39.98%, 88.57%, and 32.47% respectively. The differences of EEF and NPVR of the four subtypes were statistically significant (<i>P</i>＜0.05). The differences of abortion history, fertility history and MRI characteristics of the four subtypes were statistically significant (<i>P</i>＜0.0<i>5</i>), and the differences of treatment time, irradiation time,irradiation dose, lesion volume and ablation volume of the four subtypes after HIFU ablation were statistically significant (<i>P</i>＜0.05). Conclusions The difference of NPVR and EEF among the four subtypes after HIFU ablation was statistically significant (<i>P</i>＜0.05). Therefore, this classification based on pathology and MRI is helpful for clinical preoperative decision-making.]]></description>
<pubDate>Tue,20 Sep 2022 00:00:00  GMT</pubDate>
</item>
<item>
<title><![CDATA[Research progress of different analysis methods of resting state magnetic resonance imaging in vascular cognitive impairment no dementia]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2022.09.027</link>
<description><![CDATA[Vascular cognitive impairment no dementia (VCIND) is a transitional stage between normal aging and vascular dementia . It refers to the disease of cognitive impairment caused by vascular lesions, however, its specific pathogenesis is not very clear, and there is a lack of specific imaging diagnostic markers in clinic. Resting state functional magnetic resonance imaging (rs-fMRI) technology combined with different analysis methods is applied to the study of the mechanism of vascular cognitive impairment no dementia. It can objectively reflect the brain functional activities, obtain the characteristic imaging indexes of VCIND patients, and provide some clues to explain its mechanism. This article reviews the application of different analysis methods of rs-fMRI in VCIND research.]]></description>
<pubDate>Tue,20 Sep 2022 00:00:00  GMT</pubDate>
</item>
<item>
<title><![CDATA[Research progress of brain fMRI by acupuncture at Houxi acupoint]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2022.09.028</link>
<description><![CDATA[Houxi acupoint is widely used in clinic because of its remarkable curative effect, but its acupuncture effect mechanism is not clear. Functional magnetic resonance imaging (fMRI) has become the first choice to visually explore the central effect mechanism of acupuncture acupoints. According to the relevant literature, the fMRI study on the brain after acupuncture at Houxi acupoint mainly focuses on the influencing factors and specificity. This paper analyzes the overall research trend in this field from the above two aspects, summarizes the relevant scientific research achievements and shortcomings, provides a better imaging basis for acupuncture clinical acupoint selection, and puts forward directional suggestions for follow-up acupuncture research.]]></description>
<pubDate>Tue,20 Sep 2022 00:00:00  GMT</pubDate>
</item>
<item>
<title><![CDATA[Research progress of MRI on myelin oligodendrocyte glycoprotein antibody disease in children]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2022.09.029</link>
<description><![CDATA[Myelin oligodendrocyte glycoprotein antibody disease (MOGAD) is a new subtype of idiopathic inflammatory demyelinating disease (IIDDs) of the central nervous system in children, involving the brain, optic nerve and spinal cord. MOGAD requires individualized clinical management and specific treatment regimens, but its clinical manifestations overlap with other subtypes of IIDDs, making clinical identification difficult. MRI has the advantages of high soft tissue resolution and multi-parameter and multi-sequence imaging, which can better display the differences of neuroimaging characteristics between MOGAD and other subtypes of IIDDs, and plays an important role in the diagnosis and differential diagnosis of MOGAD. In recent years, studies on MOGAD have mainly focused on the summary and induction of imaging features of brain, optic nerve and spinal cord lesions based on MRI conventional sequences, while few studies on new sequences and new technologies have been performed on MOGAD in children. Therefore, this paper reviews the clinical and MRI research progress of MOGAD in children, in order to improve the level of understanding of the disease.]]></description>
<pubDate>Tue,20 Sep 2022 00:00:00  GMT</pubDate>
</item>
<item>
<title><![CDATA[Research progress of new MRI technology in prognosis evaluation of neonatal hypoxic-ischemic encephalopathy]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2022.09.030</link>
<description><![CDATA[Neonatal hypoxic-ischemic encephalopathy (HIE) is characterized by high mortality, many sequelae, and poor prognosis, early assessment of neurological development of HIE is of great value in diagnosis, treatment, intervention, and improvement of prognosis. MRI is currently the most valuable imaging tool for assessing the prognosis of HIE helping to predict the early and long-term neurodevelopmental outcomes of HIE. This paper aims to explore the research progress of new MRI technologies, such as diffusion-weighted imaging, diffusion tensor imaging, diffusion kurtosis imaging, magnetic resonance spectroscopy, amide proton transfer imaging, arterial spin labeling, resting-state functional magnetic resonance imaging, radiomics, and deep learning in the prognosis evaluation of HIE.]]></description>
<pubDate>Tue,20 Sep 2022 00:00:00  GMT</pubDate>
</item>
<item>
<title><![CDATA[Application and research progress of MRI on cerebral small vessel disease and vascular cognitive impairment]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2022.09.031</link>
<description><![CDATA[Cerebral small vessel disease (CSVD), the most common cause of vascular dementia, is a wide range of cerebrovascular diseases with various etiologies. The prevalence of CSVD with age, which affects the quality of life of the elderly. With the development of neuroimaging and the application of more and more new imaging technologies, the early diagnosis of CSVD and its relationship with vascular cognitive impairment have become a research hotspot. This paper reviews the role and research progress of MRI in CSVD and vascular cognitive impairment, in order to provide imaging basis for the clinical diagnosis of CSVD.]]></description>
<pubDate>Tue,20 Sep 2022 00:00:00  GMT</pubDate>
</item>
<item>
<title><![CDATA[Research progress of T2-FLAIR mismatch sign in predicting molecular typing of lower-grade glioma]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2022.09.032</link>
<description><![CDATA[T2-fluid attenuated inversion recovery (FLAIR) mismatch sign is an easily recognized imaging sign in conventional magnetic resonance imaging, which is characterized by homogenous hyperintensity of the glioma on T2WI and can be suppressed by FLAIR. A large number of studies have shown that this sign can effectively predict the molecular typing of lower–grade gliomas, especially for the prediction of isocitrate dehydrogenase (IDH) mutation and 1p/19q non-codeletion. T2-FLAIR mismatch sign has great potential in future clinical application due to its noninvasive and high specificity. In this paper, we review the definition of T2-FLAIR mismatch sign, pathological-image mechanism, and clinical application.]]></description>
<pubDate>Tue,20 Sep 2022 00:00:00  GMT</pubDate>
</item>
<item>
<title><![CDATA[Research progress in MRI of anti‐N‐methyl‐D‐aspartate receptor encephalitis]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2022.09.033</link>
<description><![CDATA[Anti‐N‐methyl‐D‐aspartate receptor (NMDAR) encephalitis is the most common type of autoimmune encephalitis, and its incidence is increasing year by year. There are many factors that can trigger the occurrence of anti‐NMDAR encephalitis, which can be divided into neoplastic and non-neoplastic types. The clinical manifestations of anti‐NMDAR encephalitis are complex and varied, and it is difficult to be diagnosed. Nearly half of the patients showed abnormal signals on conventional MRI for the first time, and advanced MRI is an effective supplement to deepen the understanding of imaging and pathology and pathophysiology of the disease. In this paper, the recent advances in conventional MRI and advanced MRI technology of anti‐NMDAR encephalitis were reviewed, in order to improve the understanding of the disease.]]></description>
<pubDate>Tue,20 Sep 2022 00:00:00  GMT</pubDate>
</item>
<item>
<title><![CDATA[Progress in the clinical application of compressed sensing technology in brain MRI]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2022.09.034</link>
<description><![CDATA[MRI is a common imaging technology in clinical practice. Due to its long scanning time, patient comfort and compliance are reduced, producing irreversible movement artifacts, resulting in impaired image quality and adverse effects on clinical diagnosis and work efficiency. Therefore, the need to shorten the MRI scanning time without affecting the image quality is very urgent. Compressed sensing (CS) technology is reconstructed and recovered by using sampling points much lower than the traditional sampling method, which can shorten the signal acquisition time. This technique can significantly shorten the scanning time, without affecting the MRI image quality, and even improve the image resolution and signal to ratio, which can well solve the above problems. Any technology requires a lot of scientific research before clinical practice to determine whether it has an impact on clinical diagnosis. In this review, we summaried the application of CS technology in craniocerebral MRI, discusses its application progress in various conventional MRI scanning sequences, and provides multi-angle information for the improvement of clinical scanning practice and CS technology and future scientific research hotspots.]]></description>
<pubDate>Tue,20 Sep 2022 00:00:00  GMT</pubDate>
</item>
<item>
<title><![CDATA[Research progress of magnetic resonance non-contrast three-dimensional coronary imaging]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2022.09.035</link>
<description><![CDATA[MR non-contrast three-dimensional coronary imaging has the unique advantages of no-radiation, no dependence on contrast agents and free breathing, which can non-invasively detect abnormalities in the coronary wall and lumen. With the continuous development of MRI sequences, acceleration technology and artificial intelligence, coronary imaging technology is also becoming more and more perfect and gradually applied in clinical practice, benefiting more patients. The application progress of coronary MRI in detecting coronary lumen and wall abnormalities is reviewed in this paper.]]></description>
<pubDate>Tue,20 Sep 2022 00:00:00  GMT</pubDate>
</item>
<item>
<title><![CDATA[Research progress in predicting axillary lymph node metastasis of breast cancer by preoperative MRI]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2022.09.036</link>
<description><![CDATA[Axillary lymph node metastasis (ALNM) is one of the important factors affecting postoperative recurrence or distant metastasis of breast cancer, and has a profound impact on the choice of treatment options and long-term quality of life for patients. At present, many prediction studies for ALNM based on MRI methodology, radiomics, and genomics have been proposed, and their conclusions have clear scientific and clinical significance. This article reviews the research progress of preoperative multiparametric MRI, MRI-based radiomics and machine learning in predicting axillary lymph node (ALN) status in breast cancer.]]></description>
<pubDate>Tue,20 Sep 2022 00:00:00  GMT</pubDate>
</item>
<item>
<title><![CDATA[Research progress of functional magnetic resonance imaging in evaluating biological behavior of hepatocellular carcinoma]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2022.09.037</link>
<description><![CDATA[Hepatocellular carcinoma (HCC) is the most common malignant tumor in the world. Its heterogeneity occurs in different aspects of disease progression. With the development of functional magnetic resonance imaging (fMRI), characteristic imaging signs and related parameters play a central role in evaluating the biological behavior of HCC. It can not only quantify the heterogeneity of HCC tissue structure, typing and cellular molecular expression, so as to comprehensively and deeply understand the changes of tumor molecular pathology, but also provides guidance for the treatment and prognosis evaluation of HCC patients. In this paper, the progress of fMRI in evaluating biological behavior of HCC is reviewed.]]></description>
<pubDate>Tue,20 Sep 2022 00:00:00  GMT</pubDate>
</item>
<item>
<title><![CDATA[Application progress of radiogenomics in the prediction of liver metastasis gene mutations in colorectal cancer]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2022.09.038</link>
<description><![CDATA[Colorectal cancer (CRC) is the one of the common gastroenteritis tumors, liver is the most common metastatic site of advanced CRC, colorectal liver metastasis (CRLM) is the main adverse factor that effects the long-term prognosis of patients. It is shown that CRLM is usually associated with the gene mutation status intimately. Traditional imaging methods still have some limitations in the prediction, diagnosis, treatment and prognosis of CRLM gene mutation. In recent years, radiogenomics has shown great potential and broad application prospects in predicting gene mutation status of CRLM, guiding treatment decision making, improving long-term prognosis and overall survival rate, and predicting treatment sensitivity.]]></description>
<pubDate>Tue,20 Sep 2022 00:00:00  GMT</pubDate>
</item>
<item>
<title><![CDATA[Progress of MRI in predicting of the tumor response after neoadjuvant chemoradiotherapy for rectal cancer]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2022.09.039</link>
<description><![CDATA[Because patients with locally advanced rectal cancer cannot directly remove the lesions, after neoadjuvant chemoradiotherapy (nCRT), some people have a more sensitive response, and a complete tumor response will occur. Therefore, local resection or "watch and wait" approach is expected to replace surgical resection for such patients, thereby preserving the patient<sup><sup>,</sup></sup>s anus and avoiding unnecessary surgical complications. Therefore, a noninvasive and reliable evaluation method is needed to determine tumor response after nCRT. MRI plays a crucial role in the initial staging of rectal cancer and in reassessing tumor response to nCRT. At present, the evaluation methods mainly include conventional MRI, functional MRI and MRI based on artificial intelligence prediction model. This paper comprehensively elaborated the research progress of the above three evaluation methods in predicting tumor response after neoadjuvant therapy for locally advanced rectal cancer.]]></description>
<pubDate>Tue,20 Sep 2022 00:00:00  GMT</pubDate>
</item>
<item>
<title><![CDATA[The latest research progress of functional MRI in traumatic cartilage injury of ankle joint]]></title>
<link>http://med-sci.cn/cgzcx/en/en_articlexml.asp?doi=10.12015/issn.1674-8034.2022.09.040</link>
<description><![CDATA[Ankle trauma often causes early injury of articular cartilage. If the articular cartilage injury is not diagnosed early, it may lead to further deterioration of the condition and induce a decrease or impairment of the patient<sup><sup>,</sup></sup>s mobility. At present, it is easy to miss the diagnosis of cartilage injury by conventional MRI scanning, and it is difficult to quantitatively evaluate the degree of cartilage injury. However, functional MRI (fMRI) can reflect the pathophysiological abnormalities of articular cartilage, and it has a high application prospect in early diagnosis and severity grading of ankle cartilage injury. To address this issue, this paper reviews the latest advances in the clinical application of fMRI techniques of ankle cartilage, in order to broaden the application scope of fMRI in early diagnosis and curative effect prediction of ankle cartilage.]]></description>
<pubDate>Tue,20 Sep 2022 00:00:00  GMT</pubDate>
</item>
</channel>
</rss>
