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• Clinical Article •
The value of diffusion-weighted MRI in the preoperative diagnosis and staging of tongue carcinoma
Chen Chen  He Zhong-yun  Long Xue-ying  Xiang Yong-hua  Tian- Qiang  Zhou Le-jiang 

DOI:10.12015/issn.1674-8034.2016.01.006.


[Abstract] objective: To investigate the potential value of diffusion weighted imaging (DWI) and the apparent diffusion coefficient (ADC) for preoperative diagnosis and staging of patients with tongue carcinoma.Materials and Methods: Thirty-four patients with tongue carcinoma underwent DWI in addition to routine MR imaging before therapy, of which 32 patients underwent surgical treatment. The staging accuracy by routine MRI and DWI was compared with surgical pathology as the reference standard.Results: (1) Estimating of lesion size and extent of infiltration, DWI-MRI was more accurate than routine MRI (P<0.05). (2) Routine MRI diagnosed 45 lymph nodes metastasis and the calculated sensitivity, specificity, accuracy was 71.0%,96.0%, 88.9%. DWI-MRI detected 53 lymph nodes metastasis, and the obtained sensitivity, specificity, accuracy was 89.3%, 89.3%,98.0% 98.8%. There was no statistical significance between them. The mean ADC values of metastasis lymph nodes and benign nodes were 0.91 × 10-3 mm2/s and 1.65 × 10-3 mm2/s, respectively (P<0.01). (3) Routine MRI made over diagnosis of 6 cases and DWI-MRI only 1 case. The accuracy of routine MRI was 82.0% and DWI was 97.0%. Compared with the two methods, there was no statistical significance between them.Conclusions: DWI was of certain advantages in displaying the range of lesion and the ADC value measurement could provide useful information for diagnosis of lymph node metastasis for tongue cancer. DWI could improve preoperative diagnosis and staging accuracy for the tongue cancer.
[Keywords] Diffusion magnetic resonance imaging；Tongue neoplasms；Lymph Nodes

Chen Chen Department of Radiology, No.331 Hospital of Zhuzhou City, Hunan Province, Zhuzhou 412002, China

He Zhong-yun* Department of Radiology, No.331 Hospital of Zhuzhou City, Hunan Province, Zhuzhou 412002, China

Long Xue-ying Department of Radiology, Xiangya Hospital, Central South University, Changsha 410008, China

Xiang Yong-hua Department of Radiology, Hunan Provincial People’s Hospital, Changsha 410005, China

Tian- Qiang Department of Radiology, No.331 Hospital of Zhuzhou City, Hunan Province, Zhuzhou 412002, China

Zhou Le-jiang Department of Radiology, No.331 Hospital of Zhuzhou City, Hunan Province, Zhuzhou 412002, China

*Correspondence to: He ZY, E-mail: hezhongyun@126.com

Conflicts of interest   None.

ACKNOWLEDGMENTS  The paper is supported by National Health and Family Planning Commission of Hunan Province 2015 Annual Scientific Research Subject Plan Project No. B2015-161
Received  2015-06-17
Accepted  2015-08-23
DOI: 10.12015/issn.1674-8034.2016.01.006
DOI:10.12015/issn.1674-8034.2016.01.006.

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