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• Clinical Article •
Specimens of colorectal cancer in vitro MRI pathological control study for signs of lymph node metastasis
MA Xiao-mei  XU Xiang-jiu  HUANG Gang  ZHOU Xing  HE Jian-wei  XIE Zong-yuan  LIU- Lu 

DOI:10.12015/issn.1674-8034.2016.01.008.


[Abstract] Objective: To summarize the metastasis signs of rectal cancer lymph node on high resolution MR and DWI, to explore the accuracy of MRI examination of benign and malignant lymph node.Materials and Methods: Fourteen patients who confirmed as rectal cancer by pathology and accepted total mesentery excision rectal cancer were included in the study, and their specimens were examined by high-resolution MRI and DWI. Then according to the pathological examination, analyze the high-resolution MRI manifestations and DWI parameters characteristics of metastasis lymph node.Results: There are 14 patients with rectal cancer were concluded in the study, specimens MRI detected 112 lymph node and postoperative pathology examination found metastasis lymph nodes 22, reactive lymph nodes 36, normal lymph node 53. Most metastasis lymph node is neither smooth edge, no uniform internal signals, compared with benign lymph nodes, the difference was statistically significant (P<0.05). Most metastasis lymph node is neither smooth edge, no uniform internal signals, compared with benign lymph nodes, the difference was statistically significant, P values were less than 0.05. The short diameter of reactive hyperplastic lymph node and metastasis lymph nodes are 0.47—0.96 cm, 0.52—0.96 cm respectively, they are greater than normal lymph nodes (0.25—0.72 cm), the difference was statistically significant (P<0.05), but the difference between the reactive hyperplastic lymph node and metastasis lymph nodes has no statistical significance (P>0.05). The ratio of short diameter and length diameter are 0.855±0.047 and 0.0273±0.006, the difference was statistically significant (P<0.05). The ADC values of metastatic lymph nodes is markedly lower than the normal lymph nodes [(0.722±0.047)×10-3 mm2/s: (0.868±0.064)×10-3 mm2/s], but with reactive hyperplastic lymph node (0.734±0.078)×10-3 mm2/s was no significant difference.Conclusions: The edge and internal signal of the lymph node within the rectal mesentery displayed clearly on high-resolution magnetic resonance imaging (MRI), it has high diagnostic value for the assessment of metastasis lymph node metastasis. DWI for distinguishing normal lymph nodes with metastasis lymph node has certain value, but to identify reactive hyperplastic lymph nodes with metastasis lymph nodes, it has no significant means.
[Keywords] Rectal neoplasms；Lymph nodes；Magnetic resonance imaging；Pathology

MA Xiao-mei Gansu University of Traditional Chinese Medicine, Lanzhou 730000, China

XU Xiang-jiu* Department of Radioligy, Gansu Province Hospital, Lanzhou 730000, China

HUANG Gang Department of Radioligy, Gansu Province Hospital, Lanzhou 730000, China

ZHOU Xing Department of Radioligy, Gansu Province Hospital, Lanzhou 730000, China

HE Jian-wei Department of Radioligy, Gansu Province Hospital, Lanzhou 730000, China

XIE Zong-yuan North China University of Science and Technology Affiliated Hospital, Tangshan 063000, China

LIU- Lu Gansu University of Traditional Chinese Medicine, Lanzhou 730000, China

*Correspondence to: Xu XJ, E-mail: xvxiangjiu@sina.com

Conflicts of interest   None.

ACKNOWLEDGMENTS  This article is funded by scientific research project of G ansu Provincial health industry No. GSWST2013-01
Received  2015-11-03
Accepted  2015-12-02
DOI: 10.12015/issn.1674-8034.2016.01.008
DOI:10.12015/issn.1674-8034.2016.01.008.

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