Share:
Share this content in WeChat
X
DWI Papers
Rectal cancer lymph node can be identified by diffusion-weighted MRI with multiple b values
LI Jian-ming  LIU Yun-xia  ZHANG Meng-chao  QU Yang-chun 

DOI:10.12015/issn.1674-8034.2016.02.003.


[Abstract] Objective: To prospectively assess the diagnostic performance of diffusion-weighted (DWI) magnetic resonance imaging(MRI) in the detection of rectal cancer metastasis lymph nodes by using multiple b values and T2 weighted Imaging.Materials and Methods: Review of 80 cases of endoscopic and postoperative pathology confirmed DWI images of rectal cancer patients of China-Japan Friendship Hospital Affiliated Jilin University; DWI multi b scan, b values was 0, 20, 30, 50, 600, 800, 1000 s/mm2; Through analysis of workstation software, based on b value generated table apparent diffusion coefficient apparent diffusion coefficient (ADC) diagram. According to pathological results, will be divided into group A/B(metastasis lymph nodes and the metastasis lymph node), retrospective measurement and analysis of different b values metastasis lymph node detection rate; Measuring the size of different lymph nodes, multiple b value of ADC figure that lymph node detection rate; Analysis of more than two sets of lymph node b value of ADC value, the measurement of lymph node metastasis of sensitivity, specificity, ROC curve drawing.Results: (1)With the increase of b value (0—1000 s/mm2), lymph node detection rate decline; Ratio that image lymph nodes signal-to-noise of DWI can increasing. (2)More than 8 mm diameter lymph nodes, b value of DWI image detection rate is consistent, be more no significant statistical difference. (3)The high field strength more b value, the difference of group A/B lymph node with ADC values was statistically significant. (4)The best cut-off point for diagnosis the nature of lymph node, ADC values is 0.98×10-3mm2/s has a moderate sensitivity, high specificity.Conclusion: Identification the nature of lymph node, high field strength b value of DWI imaging can be more effective with high specificity and medium sensitivity.
[Keywords] Rectal neoplasms;Lymph nodes;Magnetic resonance imaging;Diffusion weighted imaging

LI Jian-ming Department of Radiology, China-Japan Friendship Hospital Affiliated Jilin University, Changchun 130000, China

LIU Yun-xia* Department of Radiology, China-Japan Friendship Hospital Affiliated Jilin University, Changchun 130000, China

ZHANG Meng-chao Department of Radiology, China-Japan Friendship Hospital Affiliated Jilin University, Changchun 130000, China

QU Yang-chun Department of Radiology, China-Japan Friendship Hospital Affiliated Jilin University, Changchun 130000, China

*Correspondence to: Liu YX, E-mail: 854732649@qq.com

Conflicts of interest   None.

ACKNOWLEDGMENTS  This work was part of scientific research project of Health and Family Planning Commission of Jilin Province No. 2011I109
Received  2015-08-11
Accepted  2015-12-23
DOI: 10.12015/issn.1674-8034.2016.02.003
DOI:10.12015/issn.1674-8034.2016.02.003.

[1]
Sun YQ, Tong T. Apparent diffusion coefficient (ADC) value: a potential imaging biomarker that reflects the biological features of rectal cancer. PLoS ONE, 2014, 9(10): 109371.
[2]
Seung HK. Apparent diffusion coefficient for lymph node characterization after chemoradiation therapy for locally advanced rectal cancer. Acta Radiol December, 2015, 56(12): 1446-1453.
[3]
何云飞, 杜丽云, 靳仓正.弥散加权成像评价直肠癌淋巴结转移的价值. CT理论与应用研究, 2014, 23(2): 267-273.
[4]
Tamer F, Taha A. Neck lymph nodes: characterization with diffusion-weighted MRI. Egypt J Radiol, 2012, 43(2): 173-181.
[5]
Yamaguchi K, Schacht D, Nakazono T, et al. Diffusion weighted images of metastatic as compared with nonmetastatic axillary lymph nodes in patients with newly diagnosed breast cancer. J Magn Reson Imaging, 2014, 42(3): 771-778.
[6]
Vag T, Heck MM, Beer AJ, et al. Preoperative lymph node staging in patients with primary prostate cancer: comparison and correlation of quantitative imaging parameters in diffusion-weighted imaging and 11C-choline PET/CT. Eur Radiol, 2014, 24(8): 1821-1826.
[7]
康英杰, 张皓. 磁共振弥散加权成像在直肠癌检查中的价值.磁共振成像, 2015, 6(2): 155-160.
[8]
都雪朝, 潘卫东, 薛华丹. MRI在直肠癌诊疗中的发展过程与应用. 磁共振成像, 2015, 6(7): 549-553.
[9]
Turgut Seber, Emrah Caglar. Diagnostic value of diffusion-weighted magnetic resonance imaging: differentiation of benign and malignant lymph nodes in different regions of the body. Clinical Imaging, 2015, 5(6): 856-862.
[10]
陈泉桦, 刘彪. 乳腺MRI多b值下ADC值定量对腋窝淋巴结定性诊断价值及b值优化. 磁共振成像, 2014, 5(4): 264-268.
[11]
Thoeny HC, Froehlich JM, Triantafyllou M, et al. Metastases in normal-sized pelvic lymph nodes:detection with diffusion-weighted MR imaging. Radiology, 2014, 273(1): 125-135.
[12]
Kim JH, Beets GL, Kim MJ, et al. High-resolution MR imaging for nodal staging inrectal cancer: are there any criteria in addition to the size. Eur J Radiol, 2004, 52(1): 78-83.
[13]
Low RN, Gurney J. Diffusion-weighted MRI(DWI)in the oncology patient:value of breathhold DWI compared to unenhanced and gadolinium-enhanced MRI. J Magn Reson Imaging, 2007, 25(4): 848-858.
[14]
Mukhedi SK, Chenevert TL, Castillo M, et al. Diffusion-weighted magnetic resonance imaging. J Neurophthalmol, 2002, 22(2): 118-122.
[15]
Bammer R. Basic principles of diffusion-weighted imging. Eur J Radiol, 2003, 45(3): 169-184.
[16]
Mürtz P, Flacke S, Träber F, et al. Abdomen:diffusion-weighted MR imagingwithpulse-triggeredsingle-shotsequences. Radiology, 2002, 224(1): 258-264.
[17]
刘妍, 夏黎明, 邹明丽, 等磁共振扩散加权成像及ADC测量在淋巴结病变鉴别诊断中的价值.中国医学影像技术, 2006, 22(5): 730-732.
[18]
Razek AA, Soliman NY, Elkhamary S, et al. Role of diffusion-weighted MR imaging in cervical lymphadenopath. Euro Radiol, 2006, 16(7): 1468-1477.
[19]
King AD, Ahuja AT, Yeung DK, et al. Malignant cervial lymphadenopathy:diagnostic accuracy of diffusion-weighted MR imaging. Radiology, 2007, 245(3): 806-813.
[20]
Sumi M, van Sakihama N, Sumi T. Discrimination of metastatic cervical lymph nodes with diffusion-weighted MR imaging in patients with head and neck cancer. American Journal of Neuroradiology, 2003, 24(8): 1627-1634.

PREV Value of DWI to transplanted renals with early acute rejection: a preliminary study
NEXT Preliminary using multivoxel 1H-MRS to reveals the effect of CPAP treatment in moderate and severe OSAHS patients
  



Tel & Fax: +8610-67113815    E-mail: editor@cjmri.cn