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• Clinical Article •
Follow-up value of Multi-modality imaging in the MRI assessment of recurrence after transcatheter arterial chemo embolization combined radiofrequency ablation of nodular hepatocellular carcinoma
LV Ting-ting  LIU Ai-lian  WANG He-qing  LI Ye  CHEN Li-hua  HAN Zheng 

DOI:10.3969/issn.1674-8034.2016.02.006.


[Abstract] Objective: To study the follow-up value of Multi-modality imaging in the MRI assessment of recurrence after transcatheter arterial chemoembolization (TACE) combined radiofrequency ablation (RFA) of nodular hepatocellular carcinoma (HCC).Materials and Methods: The clinical and pathological characteristics of single nodular hepatocellular carcinoma confirmed by clinical or pathological between September 2009 and September 2014 were retrospectively collected, and the patients were treated by RFA and TACE. At last, 105 cases were screened, including 87 males and 18 females, aged 46—83 years, and median age of 63 years. The recurrence points were divided into three groups: recurrence group, suspicious group and postoperative group. Combined with the recurrence group, the changes of the serial signals and morphological signs of the other two groups were observed in the tumor recurrence region of the tumor recurrence region. Statistical analysis: using chi square test to compare the signal and morphological changes between the three groups. According to the sequence signal of the recurrence group, the percentage of the morphology of the group was number. Using the ROC curve to compare the diagnostic thresholds of the serial signals between the recurrent group and the postoperative group. Using logistics regression to calculate the sensitivity and specificity of each sequence using signal and morphological characteristics for the diagnosis of suspicious group. Then the sequence was joint, find the maximum Youden index sequence matching.Results: Signal characteristics of suspicious group: T1WI showed low signal and mixed signal; T2WI showed high signal and mixed signal; DWI showed hyperintensity LAVA (enhancement). Morphological characteristics: the sequence mostly with half. The diagnostic efficacy: when four joint use T1WI, T2WI, DWI, LAVA and combined diagnostic sensitivity and specificity were 85.7% and 94.3%.Conclusion: Multi-modality imaging of MRI has the potential to assess the recurrence after TACE combined RFA of nodular HCCs .
[Keywords] Carcinoma, hepatocellular；Magnetic resonance imaging；Transcatheter arterial chemo embolization；Radiofrequency ablation；Diffusion weighte dimaging

LV Ting-ting Department of Radiology, First Affiliated Hospital of Dalian Medical University, Dalian 116010, China

LIU Ai-lian* Department of Radiology, First Affiliated Hospital of Dalian Medical University, Dalian 116010, China

WANG He-qing Department of Radiology, First Affiliated Hospital of Dalian Medical University, Dalian 116010, China

LI Ye Department of Radiology, First Affiliated Hospital of Dalian Medical University, Dalian 116010, China

CHEN Li-hua Department of Radiology, First Affiliated Hospital of Dalian Medical University, Dalian 116010, China

HAN Zheng Department of Radiology, First Affiliated Hospital of Dalian Medical University, Dalian 116010, China

*Correspondence to: Liu AL, E-mail: cjr.liuailian@vip.163.com

Conflicts of interest   None.

Received  2015-10-25
Accepted  2015-12-30
DOI: 10.3969/issn.1674-8034.2016.02.006
DOI:10.3969/issn.1674-8034.2016.02.006.

[1]
Song DS, Bae SH. Changes of guidelines diagnosing hepatocellular carcinoma during the last ten-year period. ClinMolHepatol, 2012, 18(3): 258-267.
[2]
Rammohan A, Sathyanesan J, Ramaswami S, et al. Embolization of liver Tumors: Past, present and future. World J Radiol, 2012, 4(9): 405-412.
[3]
郭永梅, 黄云海, 魏新华, 等. 3.0 T动态增强磁共振对卵巢肿瘤的半定量及定量分析研究. 磁共振成像, 2015, 6(10): 786-789.
[4]
Peng W, Chen Y, Jiang Q, et al.Spatial analysis of hepatocellular careinoma and socioeconomic status in China from a population-based cancer registry. Cancer Epidemiol, 2010, 34(1): 29-33．
[5]
陈柱，肖恩华.肝癌介入治疗的功能性磁共振成像评价研究进展. 中华临床医师杂志（电子版), 2014, 8(1): 7-13.
[6]
过川根, 张景峰, 徐顺良. 磁共振弥散加权成像联合动态增强在肝癌患者TACE术后病灶残留及复发监测中的应用价值.浙江大学学报（医学版), 2014, 15(1): 77-88.
[7]
Dong S, Ye XD, Yuan Z, et al. Relationship of apparent diffusion coefficient to survival for patients with unresectable primary hepatocellular carcinoma after chemoembolization. Eur J Radiol, 2012, 81(3): 472-477．
[8]
Peng ZW, Zhang YJ, Chen MS, et al. Radiofrequency ablation with orwithouttranscatheter arterial chemoembolization in the treatment ofhepatocellular carcinoma: a prospective randomized trial. J Clinoncol, 2013, 31(4): 426-432.
[9]
陈志刚, 黄超源, 连芳, 等. 早期肝细胞癌射频消融联合肝动脉化疗栓塞与手术切除疗效Meta分析．中华肿瘤防治杂志, 2015, 22(1): 59-65.
[10]
JeongAh Lee, Woo KyoungJeong, YongsooKim. Dual-energy CT to detect recurrent HCC after TACE: Initial experience of color-coded iodine CT imaging. European Journal of Radiology, 2013, 82(4): 569.
[11]
陶冉, 张久权. 磁敏感技术对肝癌包膜的显示. 实用放射学杂志, 2012, 28(5): 699-702.
[12]
明韦迪, 李晓光, 薛华丹, 等. 肝癌射频消融治疗后动态增强磁共振信号的随访研究．中华临床医师杂志（电子版), 2014, 8(4): 607-610.
[13]
钱亭, 尹化斌. 功能MRI评价肝癌经肝动脉灌注化疗栓塞术疗效的研究进展. 中华放射学杂志, 2013, 47(7): 669-670.
[14]
Park HJ, Kim SH, Jang KM. Added value of diffusio-weighted MRI for evaluating viable tumor of hepatocellular carcinomas treated with radiotherapy in patients with chronic liver disease, AJR, 2014, 202(1): 92-101.
[15]
Peeraully T, Rosenbrg ML. Spontaneous intracranial hypotension without intracranial hypotension. Neueoophthalmol, 2011, 31(3): 248-251.
[16]
曲金荣, 骆俊朋, 刘翠, 等. 比较多层螺旋CT和3.0 T MR成像在肝细胞癌射频治疗疗效评价中的作用. 中华放射学杂志, 2012, 46(8): 697-700.
[17]
Thoeny HC, Ross BD. Predicting and monitoring cancer treatment response with Diffusion-Weighted MRI. Journal of Magnetic Resonance Imaging, 2010, 32(1): 2-16.

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