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• Clinical Article •
Follow-up value of Multi-modality imaging in the MRI assessment of recurrence after transcatheter arterial chemo embolization combined radiofrequency ablation of nodular hepatocellular carcinoma
LV Ting-ting  LIU Ai-lian  WANG He-qing  LI Ye  CHEN Li-hua  HAN Zheng 

DOI:10.3969/issn.1674-8034.2016.02.006.


[Abstract] Objective: To study the follow-up value of Multi-modality imaging in the MRI assessment of recurrence after transcatheter arterial chemoembolization (TACE) combined radiofrequency ablation (RFA) of nodular hepatocellular carcinoma (HCC).Materials and Methods: The clinical and pathological characteristics of single nodular hepatocellular carcinoma confirmed by clinical or pathological between September 2009 and September 2014 were retrospectively collected, and the patients were treated by RFA and TACE. At last, 105 cases were screened, including 87 males and 18 females, aged 46—83 years, and median age of 63 years. The recurrence points were divided into three groups: recurrence group, suspicious group and postoperative group. Combined with the recurrence group, the changes of the serial signals and morphological signs of the other two groups were observed in the tumor recurrence region of the tumor recurrence region. Statistical analysis: using chi square test to compare the signal and morphological changes between the three groups. According to the sequence signal of the recurrence group, the percentage of the morphology of the group was number. Using the ROC curve to compare the diagnostic thresholds of the serial signals between the recurrent group and the postoperative group. Using logistics regression to calculate the sensitivity and specificity of each sequence using signal and morphological characteristics for the diagnosis of suspicious group. Then the sequence was joint, find the maximum Youden index sequence matching.Results: Signal characteristics of suspicious group: T1WI showed low signal and mixed signal; T2WI showed high signal and mixed signal; DWI showed hyperintensity LAVA (enhancement). Morphological characteristics: the sequence mostly with half. The diagnostic efficacy: when four joint use T1WI, T2WI, DWI, LAVA and combined diagnostic sensitivity and specificity were 85.7% and 94.3%.Conclusion: Multi-modality imaging of MRI has the potential to assess the recurrence after TACE combined RFA of nodular HCCs .
[Keywords] Carcinoma, hepatocellular；Magnetic resonance imaging；Transcatheter arterial chemo embolization；Radiofrequency ablation；Diffusion weighte dimaging

LV Ting-ting Department of Radiology, First Affiliated Hospital of Dalian Medical University, Dalian 116010, China

LIU Ai-lian* Department of Radiology, First Affiliated Hospital of Dalian Medical University, Dalian 116010, China

WANG He-qing Department of Radiology, First Affiliated Hospital of Dalian Medical University, Dalian 116010, China

LI Ye Department of Radiology, First Affiliated Hospital of Dalian Medical University, Dalian 116010, China

CHEN Li-hua Department of Radiology, First Affiliated Hospital of Dalian Medical University, Dalian 116010, China

HAN Zheng Department of Radiology, First Affiliated Hospital of Dalian Medical University, Dalian 116010, China

*Correspondence to: Liu AL, E-mail: cjr.liuailian@vip.163.com

Conflicts of interest   None.

Received  2015-10-25
Accepted  2015-12-30
DOI: 10.3969/issn.1674-8034.2016.02.006
DOI:10.3969/issn.1674-8034.2016.02.006.

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