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Clinical features and MRI findings of wernicke encephalopathy
ZHANG Shuang  PENG Ru-chen  XIN Rui-qiang  YANG Yan-hui  ZHENG Jing-li 

DOI:10.12015/issn.1674-8034.2016.02.010.


[Abstract] Objective: To investigate the clinical and MR imaging features of wernicke encephalopathy(WE).Materials and Methods: Retrospective analysis in February 2010 to June 2015, the clinical diagnosis of 10 cases of wernicke encephalopathy in patients with clinical and MRI image data.Results: Three of ten patients showed changes in consciousness and psychiatric syptoms, Three patients had ocular manifestations, and four had ataxia. On MR imaging, six patients had evidence of symmetric lesions in the medial thalami and in the periventricular region of the third or four ventricle, and in periaqueductal area. Two patients had evidence of mamillary bodies, column of the fornix; Two patient had evidence of tectal plate, mamillary bodies, periaqueductal area, bilateral signal-intensity alterations of the pre- and postcentral cortex. The imaging findings were hyperintensity on T2-weighted or T1-weighter and fluid-attenuated inversion recovery (FLAIR) images.Conclusion: Contrast enhancement in the mamillary bodies and thalamus is a typical finding of the disease in WE patients. MR imaging has a valuable diagnostic role in diagnosing early WE except for clinical symptoms.
[Keywords] Wernicke’s encephalopathy；Magnetic resonance imaging；Diffusion weighted imaging；Vit-B1

ZHANG Shuang Department of Radiology, BeiJing LuHe Hospital, Capital Medical University, Beijing 101100, China

PENG Ru-chen* Department of Radiology, BeiJing LuHe Hospital, Capital Medical University, Beijing 101100, China

XIN Rui-qiang Department of Radiology, BeiJing LuHe Hospital, Capital Medical University, Beijing 101100, China

YANG Yan-hui Department of Radiology, BeiJing LuHe Hospital, Capital Medical University, Beijing 101100, China

ZHENG Jing-li Department of Radiology, BeiJing LuHe Hospital, Capital Medical University, Beijing 101100, China

*Correspondence to: Peng RC, E-mail: 13501271260@163.com

Conflicts of interest   None.

Received  2015-11-23
Accepted  2016-01-04
DOI: 10.12015/issn.1674-8034.2016.02.010
DOI:10.12015/issn.1674-8034.2016.02.010.

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