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The research status of magnetic resonance imaging in Parkinson’s disease patients with depression
ZHU Ying-cheng  SHENG Ke  CHENG Ou-mei 

DOI:10.12015/issn.1674-8034.2016.03.012.


[Abstract] Parkinson's disease is a common neurodegenerative disease in the elderly, PD patients were mainly with the onset of motor disorders, but the incidence of non motor symptoms is also very high, the incidence of depression was the highest among the non motor symptoms. The symptoms of depression have a serious impact on the quality of life of patients with Parkinson's disease, and it is also an important factor to increase the motor impairment, cognitive impairment, accelerate the development of the disease and the effect of the treatment, but the mechanism is not clear. At present, functional imaging studies suggest that the pathogenesis of PD with depression may be related to the pathogenesis of dopamine neurons, 5-serotonin neurons and prefrontal-limbic system.
[Keywords] Parkinson disease；Depression；Magnetic resonance imaging

ZHU Ying-cheng Department of Neurology, the First Affiliated Hospital of Chongqing Medical University, Chongqing 400016, China

SHENG Ke Internal Medicine, Hospital of Chongqing University, Chongqing 400044, China

CHENG Ou-mei* Department of Neurology, the First Affiliated Hospital of Chongqing Medical University, Chongqing 400016, China

*Correspondence to: Cheng OM, E-mail: chengoumei01@aliyun.com

Conflicts of interest   None.

ACKNOWLEDGMENTS  This paper is supported by the National Natural Science Foundation of China No. 81471334
Received  2016-01-13
Accepted  2016-02-13
DOI: 10.12015/issn.1674-8034.2016.03.012
DOI:10.12015/issn.1674-8034.2016.03.012.

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