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• Clinical Article •
The value of "swallow tail" appearance of nigrosome on ESWAN at 3.0 T MR in the diagnosis of Parkinson’s disease
LIU Tai-yuan  BAI Yan  MA Xiao-yue  MA Lun  SHI Da-peng  DOU She-wei  WANG Mei-yun 

DOI:10.12015/issn.1674-8034.2016.04.005.


[Abstract] Objective: To explore the value of Enhanced gradient echo T2 star weighted angiography (ESWAN) findings of nigrosome at 3.0 T MR imaging in the diagnosis of Parkinson’s Disease (PD).Materials and Methods: The ESWAN findings of 58 patients with PD and 364 age-matched healthy control were retrospectively analyzed. All the subjects were divided into PD and non-PD group according to the presence or absence of nigrosome 1 on ESWAN imaging, e.g. "swallow tail" appearance, and the accuracy was evaluated.Results: Fifty-five (94.83%) of 58 PD patients did not show "swallow tail" appearance and the rest 3 were doubtful, while 344 (94.51%) of 364 non-PD patients did have this appearance. The sensitivity of "swallow tail" appearance in differentiating PD from non-PD patients was 95% and the specifity was 91%.Conclusion: The absence of "swallow tail" appearance in nigrosome on ESWAN imaging at 3.0 T MRI provides a new, easy and reliable tool for the diagnosis of PD.
[Keywords] Magnetic resonance imaging；Swallow tail；Parkinson's disease

LIU Tai-yuan Department of Radiology, Zhengzhou University People’s Hospital & Henan Provincial People’s Hospital, Zhengzhou 450003, China

BAI Yan Department of Radiology, Zhengzhou University People’s Hospital & Henan Provincial People’s Hospital, Zhengzhou 450003, China

MA Xiao-yue Department of Radiology, Zhengzhou University People’s Hospital & Henan Provincial People’s Hospital, Zhengzhou 450003, China

MA Lun Department of Radiology, Zhengzhou University People’s Hospital & Henan Provincial People’s Hospital, Zhengzhou 450003, China

SHI Da-peng Department of Radiology, Zhengzhou University People’s Hospital & Henan Provincial People’s Hospital, Zhengzhou 450003, China

DOU She-wei Department of Radiology, Zhengzhou University People’s Hospital & Henan Provincial People’s Hospital, Zhengzhou 450003, China

WANG Mei-yun* Department of Radiology, Zhengzhou University People’s Hospital & Henan Provincial People’s Hospital, Zhengzhou 450003, China

*Correspondence to: Wang MY, E-mail: mywang@ha.edu.cn

Conflicts of interest   None.

ACKNOWLEDGMENTS  This work was part of National Natural Science Foundation No. 31470047, 81271565 Henan Province Scientific and Technological Innovation Talents Project
Received  2016-01-09
Accepted  2016-03-04
DOI: 10.12015/issn.1674-8034.2016.04.005
DOI:10.12015/issn.1674-8034.2016.04.005.

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