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• Academic Debate •
The system applying and analyzing of Z spectrum in chemical exchange saturation transfer
BAI Shuai  HOU Yu-qing  HE Xiao-wei  XUE Xin-yu 

DOI:10.12015/issn.1674-8034.2016.04.010.


[Abstract] Objective: To create a simple and friendly software toolkit to display and analyze Z spectrum of Chemical Exchange Saturation Transfer (CEST), which is convenient for clinicians and researchers to apply and research.Materials and Methods: The data is collected by conventional CEST imaging method, and the system is made by MATLAB GUI. Fitting the Z spectrum of different region of interest (ROI) which are selected by taking the mouse, and also carrying on its analysis and comparison.Results: The different positions and different pixel values of image’s ROI, the Z spectrum are different, which reflect different biological information.Conclusion: Z spectrum directly determines the final CEST signal analysis and relates biomedical information extraction. The functions of this system mainly include CEST image denoising, the formation of asymmetric magnetization transfer rate (MTRasym) mapping, selecting ROI and fitting the Z spectrum. To fit the Z spectra of ROI which are selected by taking the mouse.
[Keywords] Chemical exchange saturation transfer；Region of interest；Z spectrum；Magnetic resonance imaging

BAI Shuai College of information science and technology, Northwest University, Xi'an 710127, China

HOU Yu-qing College of information science and technology, Northwest University, Xi'an 710127, China

HE Xiao-wei* College of information science and technology, Northwest University, Xi'an 710127, China

XUE Xin-yu College of information science and technology, Northwest University, Xi'an 710127, China

*Correspondence to: He XW, E-mail: hexw@nwu.edu.cn

Conflicts of interest   None.

ACKNOWLEDGMENTS  This work was part of project of National Natural Science Foundation of China No. 61372046
Received  2016-01-07
Accepted  2016-03-31
DOI: 10.12015/issn.1674-8034.2016.04.010
DOI:10.12015/issn.1674-8034.2016.04.010.

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