Share：
Share this content in WeChat
X
[Chinese][PDF]74074
• Prostate Papers •
The diagnostic ability of T2WI combined with diffusion weighted imaging and dynamic contrast-enhanced MRI for prostate cancer detection using 3.0 T MR scanner
LIANG Jie  JI Jian-wei  FAN Zi-jian  ZHANG Li  WANG Xian-liang 

DOI:10.12015/issn.1674-8034.2016.05.004.


[Abstract] Objective: To evaluate the diagnostic ability of T2-weighted imaging (T2WI) combined with diffusion weighted imaging (DWI) and dynamic contrastenhanced MRI (DCE-MRI) for prostate cancer detection using 3.0 T MR scanner.Materials and Methods: Seventy-five prostate diseases patients pathologically proved underwent MRI examinations, including 40 patients with prostate cancer and 35 patients with non-prostate cancer. All patients were performed traditional MRI (T2WI) and functional MRI (DWI and DCE-MRI). The data obtained from T2WI, T2WI and DWI, T2WI and DCE and a combination of T2WI, DWI and DCE were scored and compared with pathological findings. Specificities, sensitivities and accuracies of the four protocols to diagnose PCa were evaluated.Results: The sensitivity and accuracy of four methods to prostate cancer diagnostic showed statistical significance (Q=15.391, 15.61, respectively. P<0.01). Pairwise comparison of sensitivity and accuracy between four methods, there was significant differences between T2WI and T2WI+DWI+DCE, T2WI+DCE and T2WI+DWI+DCE (P<0.05).Conclusions: The combination of T2WI and DWI and DCE-MRI can improve the sensitivity and accuracy of prostate cancer detection, and be of high diagnostic value for prostate cancer. The diagnosis efficiency of T2WI+DWI was slightly worse than T2WI+DWI+DCE, when elderly patients were hard to be checked for a long time, it can be as conventional MRI sequences.
[Keywords] Prostatic neoplasms；Magnetic resonance imaging

LIANG Jie Department of Medical Imaging of Weifang Medical University, Weifang 261053, China

JI Jian-wei Department of Medical Imaging, the People's Hospital of Zhucheng, Zhucheng 262200, China

FAN Zi-jian Department of Medical Imaging of Weifang Medical University, Weifang 261053, China

ZHANG Li Department of Medical Imaging of Weifang Medical University, Weifang 261053, China

WANG Xian-liang* Department of Medical Imaging, the People's Hospital of Weifang, Weifang 261041, China

*Correspondence to: Wang XL, E-mail: wangxianliang2011@126.com

Conflicts of interest   None.

Received  2016-01-31
Accepted  2016-04-02
DOI: 10.12015/issn.1674-8034.2016.05.004
DOI:10.12015/issn.1674-8034.2016.05.004.

[1]
王利伟，王牧，王绍娟, 等. MR扩散加权成像诊断前列腺癌的价值分析. 磁共振成像, 2014, 5(3): 198-201.
[2]
方俊华，闵祥德，冯朝燕, 等. 磁共振灌注加权成像定量参数在前列腺外周带前列腺癌鉴别诊断中的价值．磁共振成像, 2015, 6(2): 136-140.
[3]
Weinreb JC, Barentsz JO, Choyke PL, et al. PI-RADS Prostate Imaging-Reporting and Data System: 2015, Version 2. Eur Urol, 2016, 69(1): 16-40.
[4]
Ikonen S, Karkkainen P, Kivisaari L, et al. Endorectal magnetic resonance imaging of prostatic cancer:comparison between fat-suppressed T2-weighted fast spin echo and three-dimensional dualecho, steady-state sequences. Eur Radiol, 2001, 11(2): 236-241.
[5]
Miao H, Fukatsu H, Ishigaki T. Prostate cancer detection with 3 T MRI: comparison of diffusion-weighted and T2-weighted imaging. Eur J Radiol, 2007, 61(2): 297-302.
[6]
Kirkham AP, Emberton M, Allen C, et al. How good is MRI atdetecting and characterising cancer within the prostate? Eur Urol, 2006, 50(6): 1163-1174.
[7]
Turkbey B, Albert PS, Kurdziel K, et al. Imaging localized prostate cancer: current approaches and new developments. AJR Am J Roentgenol, 2009, 192(6): 1471-80.
[8]
Ren J, Huan Y, Ge Y, et al. Seminal vesicle invasion in prostate cancer: prediction with combined T2-weighted and diffusion - weighted MR imaging. Eur Radiol, 2009, 19(10): 2881-2486.
[9]
Franiel T, Ludemann L, Rudolph B, et al. Evaluation of normal prostate tissue, chronic prostatitis, and prostate cancer by quantitative perfusion analysis using a dynamic contrastenhanced inversion-prepared dual-contrast gradient echo sequence. Invest Radiol, 2008, 43(7): 481-487.
[10]
Ocak I, Bernardo M, Metzger G, et al. Dynamic contrast enhanced MRI of prostate cancer at 3 T: a study of pharmacokinetic parameters. AJR Am J Roentgenol, 2007, 189 (4): 849.
[11]
张盛箭，彭卫军，周良平. 动态增强MRI基本原理及其在前列腺癌中的应用. 中国医学影像技术, 2010, 26(2): 378-380.
[12]
Bloch BN, Furman HE, Hclbich TH, et al. Prostate cancer: accurate determination of extracapsular extension with high - spatial-resolution dynamic contrast-enhanced and T2-Weighted MR imaging. Initial results. Radiology, 2007, 245(1): 176-185.
[13]
肖利华. 郑晓林. 范宪淼. 磁共振弥散加权成像、T2加权成像及动态增强联合运用对前列腺癌的诊断价值. 实用放射学杂志, 2011, 27(10): 1520-1523.

PREV Feasibility study of FA and ADC values by diffusion tensor imaging: classify abnormal signal nodules in prostate transition zone
NEXT The diagnostic value of multiple b-value diffusion weighted imaging in prostate disease
  


LINK


Tel & Fax: +8610-67113815    E-mail: editor@cjmri.cn