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• Clinical Article •
1H magnetic resonance spectroscopy studies on subclinical neurocysticercosis
WANG Qing  ZHANG Cheng-zhi  LI Xin-xiang  XU Kun  SU Jie 

DOI:10.12015/issn.1674-8034.2016.05.009.


[Abstract] Objective: To evaluate the clinical application of single voxel 1H magnetic resonance spectroscopy in diagnosis of subclinical neurocysticercosis.Materials and Methods: One hundred and ten cases of subclinical neurocysticercosis and 130 cases of cerebral cysticercosis (live worms stage) with contrast enhanced single voxel 1H magnetic resonance spectroscopy were screened for this study. Observation of the change in ratio of the lesions of the subclinical neurocysticercosis and some trace metabolites around the lesions was done.Results: The group of subclinical neurocysticercosis has no significant difference with normal control group in various biochemical metabolites. The ratios of NAA/Cho, Cho/Cr and Lip/Cr have statistical significance in the analysis and evaluation of subclinical neurocysticercosis group and live worms stage group. The ratio of NAA/Cho in subclinical neurocysticercosis group is higher than live worms stage group. The ratios of Cho/Cr and Lip/Cr of the former are lower than that of the latter. The ratios of NAA/Cho and Lip/Cr evaluate the differential diagnosis efficiency between subclinical neurocysticercosis stage and live worms stage on ROC curve.Conclusions: 1H-MRS reveals the changes in characteristics of subclinical neurocysticercosis stage and live worms stage so as to evaluate the corresponding diagnosis index of the ratios of NAA/Cho and Lip/Cr, which are of great value to early diagnosis and treatment of the neurocysticercosis.
[Keywords] Neurocysticercosis；Brain diseases；Magnetic resonance spectroscopy

WANG Qing Department of Radiology, Affiliated Hospital of Dali University, Yunnan Province, Dali 671000, China

ZHANG Cheng-zhi* Department of Radiology, Affiliated Hospital of Dali University, Yunnan Province, Dali 671000, China

LI Xin-xiang Department of Radiology, Affiliated Hospital of Dali University, Yunnan Province, Dali 671000, China

XU Kun Department of Radiology, Affiliated Hospital of Dali University, Yunnan Province, Dali 671000, China

SU Jie Department of Radiology, Affiliated Hospital of Dali University, Yunnan Province, Dali 671000, China

*Correspondence to: Zhang CZ, E-mail: dlfuzcz@163.com

Conflicts of interest   None.

ACKNOWLEDGMENTS  This study was supported by Grants the National Natural Science Foundation of China No. 81060225
Received  2015-05-05
Accepted  2016-03-24
DOI: 10.12015/issn.1674-8034.2016.05.009
DOI:10.12015/issn.1674-8034.2016.05.009.

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