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• fMRI Papers •
Research progress of functional magnetic resonance image in vulnerability to depression
LIU Guang-yao  ZHANG Jing  ZHANG Lan  LIU Hong 

DOI:10.12015/issn.1674-8034.2016.06.004.


[Abstract] Vulnerability to depression is an inner quality which can cause depression appear under certain conditions, it is the inside foundations of the disease occurrence and the researchers have pay more and more attention to it, as well as it related to biology, personality, cognition, environmental factors, there also has appeared a lot of theoretical research. In recent years with the development of fMRI technology in the neuropsychiatric field, the researchers began to use fMRI to explore the neurobiological foundations of the vulnerability to depression. Using fMRI we examined the features of brain structure and brain function in resting state in subjects with vulnerability to depression, and explored their specificity of the biomarker, in order to provide new clue to neurobiological basis of vulnerability to depression associated with phatophysiological mechanism. In the current paper, we tried to provide a review of fMRI studies focusing on the following aspects: the definition and classification of vulnerability to depression, the brain structure and function changes in depression susceptible.
[Keywords] Depression disorder；Vulnerability to depression；Magnetic resonance imaging, functional

LIU Guang-yao Department of Magnetic Resonance Imaging, Lanzhou University Second Hospital, Lanzhou 730050, China

ZHANG Jing* Department of Magnetic Resonance Imaging, Lanzhou University Second Hospital, Lanzhou 730050, China

ZHANG Lan Department of Psychological health, Lanzhou University Second Hospital, Lanzhou 730050, China

LIU Hong Department of Magnetic Resonance Imaging, Lanzhou University Second Hospital, Lanzhou 730050, China

*Correspondence to: Zhang J, E-mail: lztong2001@163.com

Conflicts of interest   None.

ACKNOWLEDGMENTS  This work was part of Youth Science and Technology Fund Project of Gansu No. 1506RJYA218
Received  2016-01-11
Accepted  2016-03-02
DOI: 10.12015/issn.1674-8034.2016.06.004
DOI:10.12015/issn.1674-8034.2016.06.004.

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