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• fMRI Papers •
Research progress of functional magnetic resonance image in vulnerability to depression
LIU Guang-yao  ZHANG Jing  ZHANG Lan  LIU Hong 

DOI:10.12015/issn.1674-8034.2016.06.004.


[Abstract] Vulnerability to depression is an inner quality which can cause depression appear under certain conditions, it is the inside foundations of the disease occurrence and the researchers have pay more and more attention to it, as well as it related to biology, personality, cognition, environmental factors, there also has appeared a lot of theoretical research. In recent years with the development of fMRI technology in the neuropsychiatric field, the researchers began to use fMRI to explore the neurobiological foundations of the vulnerability to depression. Using fMRI we examined the features of brain structure and brain function in resting state in subjects with vulnerability to depression, and explored their specificity of the biomarker, in order to provide new clue to neurobiological basis of vulnerability to depression associated with phatophysiological mechanism. In the current paper, we tried to provide a review of fMRI studies focusing on the following aspects: the definition and classification of vulnerability to depression, the brain structure and function changes in depression susceptible.
[Keywords] Depression disorder；Vulnerability to depression；Magnetic resonance imaging, functional

LIU Guang-yao Department of Magnetic Resonance Imaging, Lanzhou University Second Hospital, Lanzhou 730050, China

ZHANG Jing* Department of Magnetic Resonance Imaging, Lanzhou University Second Hospital, Lanzhou 730050, China

ZHANG Lan Department of Psychological health, Lanzhou University Second Hospital, Lanzhou 730050, China

LIU Hong Department of Magnetic Resonance Imaging, Lanzhou University Second Hospital, Lanzhou 730050, China

*Correspondence to: Zhang J, E-mail: lztong2001@163.com

Conflicts of interest   None.

ACKNOWLEDGMENTS  This work was part of Youth Science and Technology Fund Project of Gansu No. 1506RJYA218
Received  2016-01-11
Accepted  2016-03-02
DOI: 10.12015/issn.1674-8034.2016.06.004
DOI:10.12015/issn.1674-8034.2016.06.004.

[1]
Alloy LB, Abramson LY, Walshaw PD, et al. A cognitive vulnerability-stress perspective on bipolar spectrum disorders in a normative adolescent brain,cognitive,and emotional development context. Dev Psychopathol, 2006, 18(4): 1055-1103.
[2]
Scher CD, Ingram RE, Segal ZV. Cognitive reactivity and vulnerability: empirical evaluation of construct activation and cognitive diatheses in unipolar depression. Clin Psychol Rev, 2005, 25(4): 487-510.
[3]
Solomon MB, Herman JP. Sex differences in psychopathology: of gonads,adrenals and mental illness. Physiol Behav, 2009, 97(2): 250-258.
[4]
Freeman EW, Sammel MD, Lin H, et al. Associations of hormones and menopausal status with depressed mood in women with no history of depression. Archives of General Psychiatry, 2006, 63(4): 375-382.
[5]
Munakata K, Fujii K, Nanko S, et al. Sequence and functional analyses of mtDNA in a maternally inherited family with bipolar disorder and depression. Mutat Res, 2007, 617(1-2): 119-124.
[6]
Clarke H, Flint J, Attwood AS, et al. Association of the 5- HTTLPR genotype and unipolar depression: A meta-analysis. Psychological medicine, 2010, 40(11): 1767.
[7]
张玉桃，吴岚，张生丛, 等. 抑郁相关人格维度与人格特质的关系及其对抑郁的影响. 中华行为医学与脑科学杂志, 2014, 23(7): 615-618.
[8]
Paulus DJ, Vanwoerden S, Norton PJ, et al. Emotion dysregulation,psychological inflexibility,and shame as explanatory factors between neuroticism and depression. J Affect Disord, 2016, 190: 376-385.
[9]
Subica AM, Allen JG, Frueh BC, et al. Disentangling depression and anxiety in relation to neuroticism,extraversion,suicide,and self-harm among adult psychiatric inpatients with serious mental illness. Br J Clin Psychol, 2015, 12(30): 1-22.
[10]
Floyd M, Scogin F, Chaplin WF. The dysfunctional attitudes scale: factorstructure,reliability,and validity with older adults．Aging Ment Health,2004,8(2): 153-160. Aging Ment Health, 2004, 8(2): 153-160.
[11]
Liu RT, Kleiman EM, Nestor BA, et al. The Hopelessness Theory ofDepression: A Quarter Century in Review. Clin Psychol (New York), 2015, 22(4): 345-365.
[12]
Spinhoven P, Drost J, van Hemert B, et al. Common rather than unique aspects of repetitive negative thinking are related to depressive and anxiety disorders and symptoms. J Anxiety Disord, 2015, 6(33): 45-52.
[13]
Hayden EP, Olino TM, Mackrell SV, et al. Cognitive vulnerability to depression during middle childhood: Stability and associations with maternal affective styles and parental depression. Pers Individ Dif, 2013, 55(8): 892-897.
[14]
Kamiya Y, Timonen V, Kenny RA, et al. The impact of childhood sexual abuse on the mental and physical health,and healthcare utilization of older adults. Int Psychogeriatr, 2015, 10(19): 1-8.
[15]
赵景欣，刘霞. 农村留守儿童的抑郁和反社会行为：日常积极事件的保护作用. 心理发展与教育, 2010, 6(26): 634-640.
[16]
房俊芳，王倩，王滨, 等. 功能MRI揭示抑郁症脑结构及功能变化的应用及展望. 磁共振成像, 2015, 6(1): 52-57.
[17]
Pezawas L, Meyer-Lindenberg A, Drabant EM, et al. 5- HTTLPR polymorphism impacts human cingulate-amygdala interactions: a genetic susceptibility mechanism fordepression. Nat Neurosci, 2005, 8(6): 828-834.
[18]
Ladouceur CD, Almeida JR, Birmaher B, et al. Subcortical gray matter volume abnormalities in healthy bipolar offspring: potential neuroanatomical risk marker for bipolar disorder?. J Am Acad Child Adolesc Psychiatry, 2008, 47(5): 532-539.
[19]
Amico F, Meisenzahl E, Koutsouleris N, et al. Structural MRI correlates for vulnerability and resilience to major depressive disorder. Journal of Psychiatry & Neuroscience, 2011, 36(1): 15-22.
[20]
张小崔，廖坚，朱雪玲, 等. 抑郁症认知易感者杏仁核体积的研究. 中国临床心理学杂志, 2011, 19(1): 10-13.
[21]
Zhang X, Yao S, Zhu X, et al. Gray matter volume abnormalities in individuals with cognitive vulnerability to depression: A voxel-based morphometry study. J Affect Disord, 2012, 136(3): 443-452.
[22]
阎锐，姚志剑，汤浩, 等. 首发抑郁症患者脑区低频振幅特征与症状群的相关性. 中华行为医学与脑科学杂志, 2014, 23(8): 673-675.
[23]
谭雅容，王阳，张宁, 等. 首发轻中度抑郁症患者认知行为治疗前后大脑局部变化的功能磁共振研究. 中华行为医学与脑科学杂志, 2014, 23(6): 490-493.
[24]
张小崔. 抑郁认知易感者脑结构及静息态脑功能的磁共振成像研究. 长沙: 中南大学, 2014.
[25]
Rao H, Gillihan SJ, Wang J, et al. Genetic variation in serotonin transporter alters resting brain function in healthy individuals. Biol Psychiatry, 2007, 62(6): 600-606.
[26]
Liu Z, Xu C, Xu Y, et al. Decreased regional homogeneity in insula and cerebellum: a resting-state fMRI study in patients with major depression and subjects at high risk for major depression. Psychiatry Res, 2010, 182(3): 211-215.
[27]
谢生辉，牛广明，高阳, 等. 首发抑郁症脑局部一致性静息态MRI对比研究. 磁共振成像, 2015, 6(1): 10-14.
[28]
Wei L, Duan X, Yang Y, et al. The synchronization of spontaneous BOLD activity predicts extraversion and neuroticism. Brain Research, 2011, 10(1419): 68-75.

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