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• Clinical Article •
Study of MRI enhancement and diffusion weighted imaging in the recurrence of nasopharyngeal carcinoma after radiotherapy
ZHONG Hua  DAI Hai-yang  LI Li-hong  LI Xin  LIU Jin-wen 

DOI:10.12015/issn.1674-8034.2016.06.007.


[Abstract] Objective: To investigate the value of conventional MRI plane scan/enhancement and diffusion weighted imaging (DWI) in the diagnosis of nasopharyngeal carcinoma (NPC) after radiotherapy.Materials and Methods: Three hundred and eighty patients proved nasopharyngeal carcinoma by biopsy were collected in our hospital. All patients were treated with radiation therapy and received a regular follow up ranging from 6 months to 3 years and MRI scan for no less than one time. Conventional MRI examinations including plan scan and Gd-DTPA enhancement, and 168 patients were scanned with DWI.Results: During the follow up, 32 patients were confirmed NPC recurrence after radiotherapy. New occurred tumors showed irregular shapes, iso-or slightly low signal on T1WI, iso-or slightly higher signal on T2WI, and moderate to obvious enhanced after contrast medium administrated. Nineteen cases were found newly occurred bone destruction in the skull base, and 12 cases were found lymph node enlargement. On DWI, recurred tumors showed moderate or high signals, and the ADC value was (0.96±0.08)×10-3 mm2/s. While most none recurrence cases showed iso-or slightly high signal while some showed slightly low signal on DWI, and the ADC value was (1.31±0.16)×10-3 mm2/s, and the difference of ADC value between two groups has statistical significance (P<0.05).Conclusion: MRI enhancement and DWI have great value in the diagnosis of recurrence of nasopharyngeal carcinoma after radiotherapy.
[Keywords] Nasopharyngeal neoplasms；Magnetic resonance imaging；Diffusion weighted imaging；Radiotherapy

ZHONG Hua Department of Radiology, Huizhou Municipal Central Hospital, Huizhou 516001, China

DAI Hai-yang* Department of Radiology, Huizhou Municipal Central Hospital, Huizhou 516001, China

LI Li-hong Department of Radiology, Huizhou Municipal Central Hospital, Huizhou 516001, China

LI Xin Department of Radiology, Huizhou Municipal Central Hospital, Huizhou 516001, China

LIU Jin-wen Department of Radiology, Huizhou Municipal Central Hospital, Huizhou 516001, China

*Correspondence to: Dai HY, E-mail: d.ocean@163.com

Conflicts of interest   None.

ACKNOWLEDGMENTS  This work was part of Medical science and technology research foundation of Guangdong Province No. A2015536 the key support project of Huizhou Municipal Central Hospital No. 2015013
Received  2016-03-03
Accepted  2016-04-18
DOI: 10.12015/issn.1674-8034.2016.06.007
DOI:10.12015/issn.1674-8034.2016.06.007.

[1]
梁菊香，邓新源，罗志程, 等. MRI动态增强技术对鼻咽癌放疗后局部纤维化与复发的诊断研究. 中国CT和MRI杂志, 2014, 12(8): 111-114.
[2]
谢传淼，梁碧玲，林浩皋, 等. MRI对鼻咽癌T、N分期的影响.中华肿瘤杂志, 2002, 24(2): 181-184.
[3]
李贻卓，吴沛宏，崔智文. 鼻咽癌放疗后局部复发和纤维变的CT动态增强研究. 中国医学影像学杂志, 2000, 8(1): 25-26.
[4]
秦方辉，汪洋，孙宗琼, 等. MRI增强扫描在鼻咽癌放疗近期疗效评估中的应用价值. 磁共振成像, 2015, 6(6): 426-429.
[5]
钟镜联，梁碧玲，丁忠祥, 等. 应用MRI动态增强技术鉴别鼻咽癌放疗后枕骨斜坡纤维化与肿瘤复发. 癌症, 2006, 25(1): 105-109.
[6]
Lin GW, Wang LX, Ji M, et al. The use of MR imaging to detect residual versus recurrent nasopharyngeal carcinoma following treatment with radiation therapy. Eur J Radiol, 2013, 82(12): 2240-2246.
[7]
Teo PT, Tan NC, Khoo JB. Imaging appearances for recurrent nasopharyngeal carcinoma and post-salvage nasopharyngectomy. Clin Radiol, 2013, 68(11): 629-638.
[8]
Li H, Wang DL, Liu XW, et al. MRI signal changes in the skull base bone after endoscopic nasopharyngectomy for recurrent NPC: a serial study of 9 patients. Eur J Radiol, 2013, 82(2): 309-315.
[9]
李建鹏，邹玉坚，郑晓林, 等. 鼻咽癌放疗后复发与纤维化DE-MRI的特征及病理对照研究. 放射学实践, 2014, 29(8): 917-920.
[10]
曹慧芳，张敏，胡姣. MRI与18F-FDGPET/CT在鉴别鼻咽癌放射治疗后局部复发与纤维化的应用研究. 中国CT和MRI杂志, 2011, 9(1): 34-36.
[11]
吕建勋，徐坚民，沈新平. 鼻咽癌MRI动态增强曲线及其时间窗. 放射学实践, 2011, 26(7): 712-715.
[12]
李建鹏，邹玉坚，毕伟, 等. 动态增强MRI和18F-FDG PET/CT对鼻咽癌放疗后复发与纤维化的诊断价值. 影像诊断与介入放射学, 2015, 24(6): 471-475.
[13]
张华，李国文，谢爱民, 等. ET-CT和MRI在诊断鼻咽癌放疗后复发中的价值. 现代肿瘤医学, 2010, 18(11): 2123-2127.
[14]
王琛，赖少侣，刘丽东, 等. 扩散加权成像诊断鼻咽癌放疗后颅底斜坡复发. 中国医学影像技术, 2004, 30(7): 978-981.
[15]
Xu JF, Wu XW, Wang WQ, et al. Value of diffusion-weightedmagnetic resonance imagingon the follow-up of nasopharyngeal carcinomaafter radiotherapy. J Xray Sci Technol, 2014, 22(5): 605-612.

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