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• Clinical Article •
Study of MRI enhancement and diffusion weighted imaging in the recurrence of nasopharyngeal carcinoma after radiotherapy
ZHONG Hua  DAI Hai-yang  LI Li-hong  LI Xin  LIU Jin-wen 

DOI:10.12015/issn.1674-8034.2016.06.007.


[Abstract] Objective: To investigate the value of conventional MRI plane scan/enhancement and diffusion weighted imaging (DWI) in the diagnosis of nasopharyngeal carcinoma (NPC) after radiotherapy.Materials and Methods: Three hundred and eighty patients proved nasopharyngeal carcinoma by biopsy were collected in our hospital. All patients were treated with radiation therapy and received a regular follow up ranging from 6 months to 3 years and MRI scan for no less than one time. Conventional MRI examinations including plan scan and Gd-DTPA enhancement, and 168 patients were scanned with DWI.Results: During the follow up, 32 patients were confirmed NPC recurrence after radiotherapy. New occurred tumors showed irregular shapes, iso-or slightly low signal on T1WI, iso-or slightly higher signal on T2WI, and moderate to obvious enhanced after contrast medium administrated. Nineteen cases were found newly occurred bone destruction in the skull base, and 12 cases were found lymph node enlargement. On DWI, recurred tumors showed moderate or high signals, and the ADC value was (0.96±0.08)×10-3 mm2/s. While most none recurrence cases showed iso-or slightly high signal while some showed slightly low signal on DWI, and the ADC value was (1.31±0.16)×10-3 mm2/s, and the difference of ADC value between two groups has statistical significance (P<0.05).Conclusion: MRI enhancement and DWI have great value in the diagnosis of recurrence of nasopharyngeal carcinoma after radiotherapy.
[Keywords] Nasopharyngeal neoplasms；Magnetic resonance imaging；Diffusion weighted imaging；Radiotherapy

ZHONG Hua Department of Radiology, Huizhou Municipal Central Hospital, Huizhou 516001, China

DAI Hai-yang* Department of Radiology, Huizhou Municipal Central Hospital, Huizhou 516001, China

LI Li-hong Department of Radiology, Huizhou Municipal Central Hospital, Huizhou 516001, China

LI Xin Department of Radiology, Huizhou Municipal Central Hospital, Huizhou 516001, China

LIU Jin-wen Department of Radiology, Huizhou Municipal Central Hospital, Huizhou 516001, China

*Correspondence to: Dai HY, E-mail: d.ocean@163.com

Conflicts of interest   None.

ACKNOWLEDGMENTS  This work was part of Medical science and technology research foundation of Guangdong Province No. A2015536 the key support project of Huizhou Municipal Central Hospital No. 2015013
Received  2016-03-03
Accepted  2016-04-18
DOI: 10.12015/issn.1674-8034.2016.06.007
DOI:10.12015/issn.1674-8034.2016.06.007.

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