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• Technical Article •
Brief overview of principles and methods of quantitative susceptibility mapping
ZHENG Zhi-wei  CAI Cong-bo  CAI Shu-hui  CHEN Zhong 

DOI:10.12015/issn.1674-8034.2016.06.011.


[Abstract] Quantitative susceptibility mapping (QSM) has become a promising magnetic resonance imaging (MRI) technique for quantifying underlying magnetic properties of tissues. It provides an effective way to quantify and analyze tissue iron deposits, calcification and vessel oxygen saturation. It is also valuable in the investigation of cerebral hemorrhage, multiple sclerosis, Parkinson disease and other neurological diseases. The reconstruction of susceptibility map is a challenge work, which consists of several steps and the accuracy of susceptibility map depends on many factors. In this work, we will review the principles of quantitative susceptibility mapping and the procedure of susceptibility map reconstruction. The major methods in every step of susceptibility map reconstruction will be introduced. We will also present several major applications of QSM in clinic.
[Keywords] Quantitative susceptibility mapping；Susceptibility map reconstruction；Field fitting；Phase unwrapping；Background removing；Susceptibility inversion；Magnetic resonance imaging

ZHENG Zhi-wei Department of Electronic Science, Fujian Provincial Key Laboratory of Plasma and Magnetic Resonance, Xiamen University, Xiamen 361005, China

CAI Cong-bo Department of Communication Engineering, Xiamen University, Xiamen 361005, China

CAI Shu-hui* Department of Electronic Science, Fujian Provincial Key Laboratory of Plasma and Magnetic Resonance, Xiamen University, Xiamen 361005, China

CHEN Zhong Department of Electronic Science, Fujian Provincial Key Laboratory of Plasma and Magnetic Resonance, Xiamen University, Xiamen 361005, China

*Correspondence to: Cai SH, E-mail: shcai@xmu.edu.cn

Conflicts of interest   None.

ACKNOWLEDGMENTS  This work was supported by the National Natural Science Foundation of China No. 11275161, 81171331
Received  2016-03-04
Accepted  2016-04-10
DOI: 10.12015/issn.1674-8034.2016.06.011
DOI:10.12015/issn.1674-8034.2016.06.011.

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