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• Clinical Article •
A study of acupuncture Dazhong and Taixi acupointsbased on fMRI
ZHANG Fan  LI Xiao-ling  WU Di  ZHANG He  LI Ya-xue  ZHANG Qin-hong  SUN Zhong-ren 

DOI:10.12015/issn.1674-8034.2016.07.001.


[Abstract] Objective: Using functional magnetic resonance imaging to observe the brain blood oxygen level dependent signal change by acupuncturing the right side of kidney channel of foot shaoyin Dazhong and Taixi acupoints, to explore the relationship between efficacy and activate brain areas. To observe the brain blood oxygen level dependent signal change by acupuncturing the right side of kidney channel of foot shaoyin Dazhong and Taixi acupoints based on blood oxygen level dependent functional magnetic resonance imaging, and to explore the relationship between efficacy and activate brain areas.Materials and Methods: Using 3.0 T dual-source double gradient magnetic resonance to collect the Bold signal data of 14 healthy volunteers who were acupunctured the right side of kidney channel of foot shaoyin Dazhong and Taixi acupoints, then using SPM12 (statistical parametric mapping) to process data and statistical analysis.Results: The active cerebral areas by acupuncturing Dazhong and Taixi acupoints include: The left frontal lobe, left medial frontal gyrus (Ba44), left inferior frontal gyrus and right insula (Ba13), right frontal, right cerebellum anterior lobe, right thalamus, right cerebellar lobe, right parietal lobe(Ba22), right posteriorcentral gyrus (Ba4), deactivate brain regions include: The left side of the midbrain, the right side Limbic lobe and hippocampus (Ba17).Conclusion: Acupuncture Dazhong and Taixi acupoints can cause the relative specificity reaction helpful to early diagnosis and condition evaluation. specificity reaction of brain central nervous. Its curative effect is closely associated with the limbic system especially the thalamic activation.
[Keywords] Acupuncture points；Dazhongacupoint；Taixiacupoint；Brain；Magnetic resonance imaging

ZHANG Fan Heilong-jiang University of Traditional Chinese Medicine, Harbin 150040, China

LI Xiao-ling First Hospital Affiliated to Heilong-jiang University of Traditional Chinese Medicine, Harbin 150040, China

WU Di Heilong-jiang University of Traditional Chinese Medicine, Harbin 150040, China

ZHANG He Heilong-jiang University of Traditional Chinese Medicine, Harbin 150040, China

LI Ya-xue First Hospital Affiliated to Heilong-jiang University of Traditional Chinese Medicine, Harbin 150040, China

ZHANG Qin-hong Heilong-jiang University of Traditional Chinese Medicine, Harbin 150040, China

SUN Zhong-ren* Heilong-jiang University of Traditional Chinese Medicine, Harbin 150040, China

*Correspondence to: Sun ZR, E-mail: 1035186010@qq.com

Conflicts of interest   None.

ACKNOWLEDGMENTS  This paper is supporting by Natural Science Foundation of China No. 81373714, 81473761 This paper is supporting by Heilongjiang province natural science foundation No. D201214 This paper is supporting by Heilongjiang provincial health departmentscientificfund No. 2012-345
Received  2016-02-03
Accepted  2016-03-23
DOI: 10.12015/issn.1674-8034.2016.07.001
DOI:10.12015/issn.1674-8034.2016.07.001.

[1]
张连才，张启明．中医肾与现代西医学组织器官的相关性研究．辽宁中医药杂志, 2003, 30(8): 634-645.
[2]
Cho ZH, Chung SC, Jones JP, et al. New findings of thecorrelation between acupoints and corresponding brain cortices using functional MRI. Proc Natl Acad Sci U S A, 1998, 95(5): 2670-2673.
[3]
Zhang Q, Li A, Yue J, et al. Using functional magnetic resonance imaging to explore the possible mechanism of the action of acupuncture at Dazhong (KI4) on the functional cerebral regions of healthy volunteers. Inter Med J, 2015, 45(6): 669-671.
[4]
徐佐宇，李昂，李晓陵，等．针刺大钟穴激活脑区的功能MRI研究.磁共振成像, 2014, 5(5): 332-335.
[5]
曹丹娜，王丰，张帆，等．应用功能磁共振技术分析针刺太溪穴的降压机制．中国老年学杂志, 2015, 35(15): 4314-4316.
[6]
骆方．大钟穴的临床应用．浙江中医学院学报, 1992, 16(3): 50.
[7]
王超，雍长福．促性腺素释放激素(GnRH）的作用机制．宁夏农学院学报, 2002, 23(3): 53-55, 82.
[8]
梁文娜，李灿东，甘慧娟，等．围绝经期综合征肝郁病理与雌性激素的相关性研究．中华中医药杂志, 2011, 26(9): 1961-1963.
[9]
罗晓梅，谢守珍，陈亚琼．围绝经期潮热发病机制．生殖医学杂志, 2008, 17(6): 495-498.
[10]
Hui KK, Liu J, Marina O, et al. The integrated response of the human cerebro- cerebellar and limbic systems to acupuncture stimulation at ST36 as evidenced by fMRI. Neuroimage, 2005, 27(3): 479-496.
[11]
Fang J, Jin Z, Wang Y, et al. The salient characteristics of the central effects of acupuncture needling: limbic-paralimbic-neocortical network modulation. Hum Brain Mapp, 2008, 30(4): 1196-1206.
[12]
Claunch JD, Chan ST, Nixon EE, et al. Commonality and specificity of acupuncture action at three acupoints as evidenced by fMRI. Am J Chin Med, 2012, 40(4): 695-712.
[13]
李双成，王磊，张凯．边缘系统的构成及功能．河北医科大学学报, 2003, 24(4): 248-250.
[14]
Mayer DJ. Biological mechanisms of acupuncture. Prog Brain Res, 2000, 122: 457-477.
[15]
Reynolds DV. Surgery in the rat during electrical analgesia induced by focal brain stimulation. Science, 1969, 164(3878): 444-445.
[16]
Wager TD, Rilling JK, Smith EE, et al. Placebo- induced change in fMRI in the anticipation and experience of pain. Science, 2004, 303(5661): 1162-1167.
[17]
Maarrawi J, Peyron R, Mertens P, et al. Motor cortex stimulation for pain control induces changes in the endogenous opioid system. Neurology, 2007, 69(9): 827-834.
[18]
秦玉革，王峰，李梅，等．独刺大钟穴为主治疗虚证腰肌劳损疗效观察．上海针灸杂志, 2011, 30(11): 749-752.
[19]
韩数，霍金，金亨镐．针刺大钟穴治疗足跟痛临床疗效观察．辽宁中医药大学学报, 2012, 14(11): 145-146.
[20]
王国清，欧阳怀亮，黄泳，等．太溪穴临床应用概述．针灸临床杂志, 2013, 29(7): 34-36.
[21]
Napadow V, Dhond R, Park K, et al. Time-Variant fMRI activity in the brainstem and higher structures in response to acupuncture. Neuroimage, 2009, 47(1): 289-301.
[22]
Choi EM, Jiang F, Longhurst JC. Point specificity in acupuncture. Chin Med, 2012, 7: 4.
[23]
方继良，王小玲，荣培晶，等．针刺脑效应fMRI国际研究进展．中国中西医结合影像学杂志, 2013, 11(2): 197-202.

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