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• DWI Papers •
The value of MR intravoxel incoherent motion diffusion weighted imaging in T stage and differentiated degree of rectal adenocarcinoma
ZHANG Dan-xia  ZHU Shao-cheng  GUAN Shu  ZHANG Lin  LI Chao 

DOI:10.12015/issn.1674-8034.2016.08.001.


[Abstract] Objective: To investigate the value of intravoxel incoherent motion diffusion weighted imaging (IVIM-DWI) quantitative parameters in T stage and differentiated degree of rectal adenocarcinoma.Materials and Methods: Fourtyeight cases of rectal adenocarcinoma confirmed by colonoscopy underwent 3.0 T MR examination,their clinicopathologic data were collected (42 cases were pure adenocarcinoma, 6 cases were adenocarcinoma with partial mucinous adenocarcinoma). GE AW4.5 workstation was used to calculate the value of ADC, D, D* and f of various T stages and differentiated degree. All parameters of various T stages and differentiated degree were compared by ANOVA and comparison between the two groups by LSD.Results: The ADC and D value in various T stage and in various degrees of differentiation were all statistically significant, for rectal adenocarcinoma of T2-T4, the value of ADC were (1.200±0.117)×10-3 mm2/s, (0.913±0.104)× 10-3 mm2/s, (0.786±0.450)×10-3 mm2/s, The value of D were (0.737±0.055)×10-3 mm2/s, (0.608±0.091)×10-3 mm2/s , (0.593±0.041)×10-3 mm2/s, the value of ADC in high, medium and low differentiation were (1.353±0.080)×10-3 mm2/s, (0.984±0.028)×10-3 mm2/s, (0.808±0.075)×10-3 mm2/s respectively, the value of D in high, medium and low differentation were (0.805±0.085)×10-3 mm2/s, (0.645±0.081)×10-3 mm2/s, (0.525±0.057)×10-3 mm2/s, D* and f value were no significant difference.Conclusion: ADC and D value are able to reflect T stage and differentiation features of rectal adenocarcinoma, IVIM-DWI can serve as a complement sequence for conventional MR sequences, can provide more information to choose the best treatment.
[Keywords] Rectal neoplasms；Adenocarcinoma；Diffusion weighted imaging；Magnetic resonance imaging；Intravoxel incoherent motion

ZHANG Dan-xia Graduate Department of Xinxiang Medical University, Xinxiang 453003, China; People's Hospital of Henan Province, Zhengzhou 450003, China

ZHU Shao-cheng* People's Hospital of Henan Province, Zhengzhou 450003, China

GUAN Shu Graduate Department of Xinxiang Medical University, Xinxiang 453003, China; People's Hospital of Henan Province, Zhengzhou 450003, China

ZHANG Lin People's Hospital of Henan Province, Zhengzhou 450003, China; Zhengzhou University, Zhengzhou 450003, China

LI Chao Graduate Department of Xinxiang Medical University, Xinxiang 453003, China; People's Hospital of Henan Province, Zhengzhou 450003, China

*Correspondence to: Zhu SC, E-mail: zsc2686@163.com

Conflicts of interest   None.

Received  2016-05-26
Accepted  2016-07-25
DOI: 10.12015/issn.1674-8034.2016.08.001
DOI:10.12015/issn.1674-8034.2016.08.001.

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