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• Clinical Article •
Relationship between the diffusion-weighted imaging patterns of ischemic stroke in acute stage and the TOAST etiological type
SHEN Ting-wen  CHEN Hui-you  JIANG Liang  MAO Cun-nan  YIN Xin-dao 

DOI:10.12015/issn.1674-8034.2016.09.004.


[Abstract] Objective: To evaluate the relationship between the imaging appearance on DWI of ischemic stroke in acute stage and the TOAST etiological type.Materials and Methods: We retrospectively analysed 939 patients admitted to neurology department of our hospital who were diagnosed as acute ischemic stroke or TIA in 2012—2015, according to the patients' DWI and MRA imaging findings, clinical data and related auxiliary examinations to evaluate TOAST etiological type, using statistical methods to analyse the correlation of the imaging appearance on DWI and TOAST etiological type.Results: There were 437 cases in the single infraction group and 502 cases in the multiple infraction group. Comparing to the single infraction group, the patients in multiple infraction group were older and had higher proportion of atrial fibrillation and hyperhomocysteinemia. Proportion of patients' TOAST subtypes were: LAA 49.6%, SVO 38.9%, CE 6.3%, SUE 5.2%, and there were no patients evaluated for SOE. The imaging appearance on DWI in acute stage of ischemic stroke had relationship with the TOAST etiological type (χ2=398.470, P=0.000), 75 cases of large penetrating branch infraction (χ2=47.199, P=0.000), 175 cases of anterior circulation unilateral infraction (χ2=39.772, P=0.000) and 91 cases of anterior- posterior circulation infarction (χ2=23.967, P=0.000) were mainly related to LAA type. Two hundred and thirty-nine cases of small penetrating branch infarction were mainly related to SVO type (χ2=332.102, P=0.000).Conclusions: The imaging appearance on DWI in acute stage of ischemic stroke has relationship with the TOAST etiological type. Early DWI and MRA imaging findings can help the clinic to predict the etiology of ischemic stroke in acute stage.
[Keywords] Brain Infarction；Diffusion magnetic resonance imaging；Early diagnosis

SHEN Ting-wen Department of Radiology, Nanjing First Hospital, Affiliated Hospital of Nanjing Medical University, Nanjing 210000, China

CHEN Hui-you Department of Radiology, Nanjing First Hospital, Affiliated Hospital of Nanjing Medical University, Nanjing 210000, China

JIANG Liang Department of Radiology, Nanjing First Hospital, Affiliated Hospital of Nanjing Medical University, Nanjing 210000, China

MAO Cun-nan Department of Radiology, Nanjing First Hospital, Affiliated Hospital of Nanjing Medical University, Nanjing 210000, China

YIN Xin-dao* Department of Radiology, Nanjing First Hospital, Affiliated Hospital of Nanjing Medical University, Nanjing 210000, China

*Correspondence to: Yin XD, E-mail: y.163yy@163.com

Conflicts of interest   None.

Received  2016-06-17
Accepted  2016-08-17
DOI: 10.12015/issn.1674-8034.2016.09.004
DOI:10.12015/issn.1674-8034.2016.09.004.

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