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• Stroke MRI •
Evaluation of the morphological characteristics and infarction pattern of unilateral middle cerebral artery occlusion using high resolution magnetic resonance imaging
ZHANG Xue-feng  LIU Qi  CHEN Shi-yue  ZHAN Qian  PENG Wen-jia  CHEN Lu-guang  TIAN Xia  LU Jian-ping 

DOI:10.12015/issn.1674-8034.2016.10.001.


[Abstract] Objective: To evaluate the two different morphological characteristics and corresponding infarction pattern of unilateral middle cerebral artery occlusion using high resolution magnetic resonance imaging (HR-MRI).Materials and Methods: The data of patients with ischemic stroke in hospital diagnosed as unilateral middle cerebral artery M1 segment occlusion was retrospectively analyzed. HR-MRI and DWI were performed in all patients within 1 week of symptom onset. To observe the morphological characteristics of occlusion of the middle cerebral artery (M1) segment and the cerebral infarction type on the cranial DWI. The patients were divided into plaque formation group and non plaque formation group according to the morphological characteristics of HR-MRI. DWI lesion patterns were classified as single cerebral infarction, multiple cerebral infarction, and no cerebral infarction (TIA).Results: Forty-four patients were included in the analysis, 30 cases of plaque formation group, while 14 cases of non plaque formation group. There were 16 cases in plaque formation group with the location of occlusion in the proximal of M1 segment, 14 cases in the distal and non plaque formation group in the proximal 13 cases, while 1 case in the distal, there was significant difference between the two groups (P=0.025, χ2=4.99), the location of occlusion of plaque formation group was mostly in the proximal. Plaque formation group and non plaque formation group of single cerebral infarction in 11 cases and 5 cases respectively, multiple infarction in 15 cases and 2 cases, no infarction lesion in 4 cases and 7 cases, there were significant differences in the types of cerebral infarction between the two groups (P=0.016, χ2=8.29). Infarction pattern in plaque formation was mostly multiple cerebral infarction, but the non plaque group was single cerebral infarction or no cerebral infarction (TIA).Conclusion: HR-MRI has important value in evaluating the morphological characteristics of the lumen of middle cerebral artery occlusion. Whether there is plaque in the lumen of the occlusion or collateral formation around the trunk may be one of the important reasons for different types of cerebral infarction after middle cerebral artery occlusion.
[Keywords] Middle cerebral artery；Magnetic resonance imaging, high resolution；Stroke；Atherosclerosis

ZHANG Xue-feng Department of Radiology, Changhai Hospital, the Second Military Medical University, Shanghai 200433, China

LIU Qi Department of Radiology, Changhai Hospital, the Second Military Medical University, Shanghai 200433, China

CHEN Shi-yue Department of Radiology, Changhai Hospital, the Second Military Medical University, Shanghai 200433, China

ZHAN Qian Department of Radiology, Changhai Hospital, the Second Military Medical University, Shanghai 200433, China

PENG Wen-jia Department of Radiology, Changhai Hospital, the Second Military Medical University, Shanghai 200433, China

CHEN Lu-guang Department of Radiology, Changhai Hospital, the Second Military Medical University, Shanghai 200433, China

TIAN Xia Department of Radiology, Changhai Hospital, the Second Military Medical University, Shanghai 200433, China

LU Jian-ping* Department of Radiology, Changhai Hospital, the Second Military Medical University, Shanghai 200433, China

*Correspondence to: Lu JP, E-mail: cjr.lujianping@vip.163.com

Conflicts of interest   None.

ACKNOWLEDGMENTS  This work was part of National Natural Science Foundation of China No. 31470910 Emerging frontier technology joint research program of Shanghai municipal hospital No. SHDC12013110 Twelth five-year plan of medical key project of the People's Liberation Army No. BWS12J026
Received  2016-06-10
Accepted  2016-08-01
DOI: 10.12015/issn.1674-8034.2016.10.001
DOI:10.12015/issn.1674-8034.2016.10.001.

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