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• Stroke MRI •
The study of carotid plaque characteristic of the low risk and high risk of acute ischemic stroke based on essen stroke risk score system
LIU Bi-ying  SHE De-jun  QI Wan  XU Ya-ye  YE Cheng-bin  ZHANG Yu-yang  LIU Ying 

DOI:10.12015/issn.1674-8034.2016.10.004.


[Abstract] Objective: To investigate the difference of carotid plaque burden and plaque composition between the low risk and high risk of acute ischemic stroke (AIS) patients based on essen stroke risk score (ESRS).Materials and Methods: Forty-one patients with AIS proved by clinic and follow-up, including low risk AIS (n=25) and high risk AIS (n=16), were enrolled in this retrospective and ethics committee-approved study. Carotid plaque high-resolution MR imaging was performed in all patients, and the responsible carotid arteries were quantitatively and qualitatively analyzed. The carotid plaque burden and compositional features were compared between the low and high risk stroke patients.Results: (1) The prevalence of recurrent AIS, age, diabetes mellitus smoking and peripheral arterial disease in patients with high risk AIS were significantly greater than patients with low risk (all P<0.05). (2) There existed statistical difference between low and high risk AIS patients in normalized wall index (NWI), lumen diameter (LD), wall thickness (WT) and stenosis (all P<0.05). (3) Patients with high risk AIS had a significantly higher prevalence of fibrous cap rupture (FCR), intra-plaque hemorrhage (IPH) compared, lipid rich necrotic core (LRNC) and lumen stenosis >50% with those with low risk AIS (both P<0.05). The LRNC area, LRNC index, IPH area and IPH index in high risk AIS patients was statistically higher than that in low (all P<0.05).Conclusion: There existed some differences between low risk and high risk AIS patients, and ESRS combined with carotid plaque high-resolution MR imaging will be helpful for the stratification study for AIS patients.
[Keywords] Stroke；Essen stroke risk score；Magnetic resonance imaging；Carotid plaque

LIU Bi-ying Department of Radiology, the People's Hospital of Fujian Traditional Chinese Medicine University, Fuzhou 350004, China

SHE De-jun Department of Radiology, the First Affiliated Hospital of Fujian Medical University, Fuzhou 350005, China

QI Wan* Department of Radiology, the People's Hospital of Fujian Traditional Chinese Medicine University, Fuzhou 350004, China

XU Ya-ye Department of Radiology, the People's Hospital of Fujian Traditional Chinese Medicine University, Fuzhou 350004, China

YE Cheng-bin Department of Radiology, the People's Hospital of Fujian Traditional Chinese Medicine University, Fuzhou 350004, China

ZHANG Yu-yang Department of Radiology, the First Affiliated Hospital of Fujian Medical University, Fuzhou 350005, China

LIU Ying Department of Radiology, the First Affiliated Hospital of Fujian Medical University, Fuzhou 350005, China

*Correspondence to: Qi W, E-mail: 742860555@qq.com

Conflicts of interest   None.

ACKNOWLEDGMENTS  This work was part of Key personnel training project of Fujian Provincial health and family Planning commission No. 2013-ZQN-JC-12
Received  2016-07-12
Accepted  2016-09-23
DOI: 10.12015/issn.1674-8034.2016.10.004
DOI:10.12015/issn.1674-8034.2016.10.004.

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