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• Clinical Article •
Middle cerebral artery plaque in patients with recurrent acute ischemic stroke: studied with high-resolution magnetic resonance imaging
ZHANG Xue-feng  LIU Qi  CHEN Shi-yue  ZHAN Qian  PENG Wen-jia  CHEN Luguang  TIAN Xia  LU Jian-ping 

DOI:10.12015/issn.1674-8034.2016.11.003.


[Abstract] Objective: To study the morphological characteristics of middle cerebral artery plaque in patients with recurrent acute ischemic stroke by 3.0 T high resolution magnetic resonance imaging (HR-MRI).Materials and Methods: Retrospective analysis of clinical data of 77 cases of patients with acute ischemic stroke, the culprit plaques in middle cerebral artery, including 36 cases of patients with primary (primary group), 41 cases with recurrence (recurrence group), all patients underwent 3.0 T high resolution magnetic resonance imaging (plaque scanning sequence including TOF-MRA, DWI for the whole brain, T1WI,T2WI and contrast-enhanced T1WI). Comparative analysis of the primary and recurrent patients plaque morphological characteristics included lumen stenosis rate, minimal lumen area, plaque burden, plaque enhancement rate, T1WI and T2WI plaque signal strength index.Results: The lumen stenosis rate (P=0.002), plaque burden (P=0.005) and plaque enhancement ratio (P=0.037) were significantly higher in the recurrent group than in the primary group, and the minimal lumen area (P=0.001) was significantly smaller than that in the primary group. The T2WI signal intensity index of the recurrence group was higher than that of the primary group (P<0.001), while the T1WI signal strength index was not significantly different (P=0.245).Conclusions: High resolution magnetic resonance imaging can effectively evaluate the morphological characteristics of middle cerebral artery plaque in patients with recurrent acute ischemic stroke. Comprehensive evaluation of plaque characteristics can provide reference for the clinical and help to prevent recurrence stroke.
[Keywords] Infarction, middle cerebral artery；Magnetic resonance imaging；Plaque, atherosclerotic；Recurrence

ZHANG Xue-feng Department of Radiology, Changhai Hospital, the Second Military Medical University, Shanghai 200433, China

LIU Qi Department of Radiology, Changhai Hospital, the Second Military Medical University, Shanghai 200433, China

CHEN Shi-yue Department of Radiology, Changhai Hospital, the Second Military Medical University, Shanghai 200433, China

ZHAN Qian Department of Radiology, Changhai Hospital, the Second Military Medical University, Shanghai 200433, China

PENG Wen-jia Department of Radiology, Changhai Hospital, the Second Military Medical University, Shanghai 200433, China

CHEN Luguang Department of Radiology, Changhai Hospital, the Second Military Medical University, Shanghai 200433, China

TIAN Xia Department of Radiology, Changhai Hospital, the Second Military Medical University, Shanghai 200433, China

LU Jian-ping* Department of Radiology, Changhai Hospital, the Second Military Medical University, Shanghai 200433, China

*Correspondence to: Lu JP, E-mail: cjr.lujianping@vip.163.com

Conflicts of interest   None.

ACKNOWLEDGMENTS  The National Nature Science Foundation of China No. 31470910 The Emerging Frontier Technology Joint Research Program of Shanghai Municipal Hospital, China No. SHDC12013110 The twelth five-year plan of medical key project of the People's Liberation Army No. BWS12J026
Received  2016-09-23
Accepted  2016-10-13
DOI: 10.12015/issn.1674-8034.2016.11.003
DOI:10.12015/issn.1674-8034.2016.11.003.

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