Share：
Share this content in WeChat
X
[Chinese][PDF]88075
• Clinical Article •
Imaging and ADC value in differential diagnosis of intracranial hemangiopericytoma and anaplastic meningioma: a comparative study
CHEN Fei  SHEN Xue-jiao  MA Li  LAN Yu-xia  SUN Peng-Fei 

DOI:10.12015/issn.1674-8034.2016.11.004.


[Abstract] Objective: To analyze MRI features of intracranial hemangiopericytoma (HPC) and Anaplastic Meningioma (AM). Exploring the value of DWI and ADC value in differential diagnosis of them.Materials and Methods: The imaging data of 20 cases of HPC and 31 cases of AM pathologically confirmed were collected. They all had plain and enhanced MRI scans and diffusion weighted MRI scans. The results were analyzed in all cases.Results: Differences in tumor shape (χ2=4.763, P<0.05), hemorrhage (χ2=8.400, P<0.01), signal void of vessel (χ2=26.793, P<0.001), brain tumor interface (χ2=4.432, P<0.05), dural attachment (χ2=15.093, P<0.001), dural tail (χ2=9.670, P<0.01), enhancement (χ2=8.025, P<0.01) and homogenous enhancement (χ2=5.097, P<0.05) between HPC and AM were statistically significant. Differences in T2WI signal (χ2=3.227, P>0.05), cystic necrosis (χ2=0.658, P>0.05), peritumoral edema (χ2=0.056, P>0.05) and bone destruction (χ2=2.588, P>0.05) were not statistically significant. The former had mostly lobulated, irregular shape, cystic necrosis, hemorrhage and tumor blood flow within the empty signal more common, clear brain tumor interface, significant heterogenous enhancement, narrow base connected with dural, rare dural tail, the latter was mostly round or oval, rare cystic necrosis and hemorrhage, fuzzy brain tumor interface, significant homogenous enhancement, wide base connected with dural, dural tail more common. Twenty cases of HPC showed equal or slightly higher signal on DWI, and the ADC mean was (1.21±0.14)×10-3 mm2/s. In 28 from 31 cases of AM, DWI showed higher or slightly higher signal, 3 cases showed low signal, ADC mean was (0.82±0.12) ×10-3 mm2/s, Which was significantly lower than that of HPC (t=10.39, P<0.001). When optimal cut point of ADC was 1.07×10-3 mm2/s for diagnosis of HPC and AM, the area under the ROC curve was 0.98±0.01, 95% confidence intervals was 0.95-1.00, the sensitivity, specificity and accuracy was 90%, 100% and 90%.Conclusions: The MRI features are helpful in differential diagnosis of HPC and AM, ADC values can be applied as a complementary tool in the differential diagnosis of them, which can increase the diagnostic accuracy.
[Keywords] Hemangiopericytoma；Meningioma；Magnetic resonance imaging

CHEN Fei Department of Radiotherapy, Lanzhou University Second Hospital, Lanzhou 730030, China

SHEN Xue-jiao Department of Radiotherapy, Lanzhou University Second Hospital, Lanzhou 730030, China

MA Li Department of Radiotherapy, Lanzhou University Second Hospital, Lanzhou 730030, China

LAN Yu-xia Department of Radiotherapy, Lanzhou University Second Hospital, Lanzhou 730030, China

SUN Peng-Fei* Department of Radiotherapy, Lanzhou University Second Hospital, Lanzhou 730030, China

*Correspondence to: Sun PF, E-mail: sunpengfeiby@163.com

Conflicts of interest   None.

Received  2016-07-22
Accepted  2016-10-08
DOI: 10.12015/issn.1674-8034.2016.11.004
DOI:10.12015/issn.1674-8034.2016.11.004.

[1]
Rutkowski MJ, Sughrue ME, Kane AJ, et al. Predictors of mortality following treatment of intracranial hemangiopericytoma. J Neurosurg, 2010, 113(2): 333-339.
[2]
Louis DN, Ohgaki H, Wiestler OD, et al. The 2007 WHO classifcation of tumours of the central nervous system. Acta Neuropathol, 2007, 114(6): 97-109.
[3]
Louis DN, Perry A, Reifenberger G, et al. The 2016 World Health Organization classification of tumors of the central nervous system: a summary. Acta Neuropathol, 2016, 131(6): 803-820.
[4]
Joung HL. Meningiomas: diagnosis, treatment, and outcome. Springer, 2009, 23(6): 48-49.
[5]
白亮彩，周俊林，徐瑞,等.颅内间变型血管周细胞瘤的MR特征.实用放射学杂志, 2012, 28(8): 1186-1188.
[6]
魏晓辉，周俊林，黎卫平,等.颅内血管外皮细胞瘤囊变坏死与P73表达相关性的研究.中国临床医学影像杂志, 2010, 21(1): 9-12.
[7]
Matsushima N, Maeda M, Takamura M, et al. MRI findings of atypical meningioma with microcystic changes. J Neurooncol, 2007, 82(3): 319-321.
[8]
岳松虹，魏晋艳，周俊林,等.微囊型脑膜瘤与非典型性脑膜瘤影像学对比研究.中国医学影像学杂志, 2014, 22(12): 891-894.
[9]
Akiyama M, Sakai H, Onoue H, et al. Imaging intracranial haemangiopericytomas: study of seven cases. Neuroradiology, 2004, 46(3): 194-197.
[10]
陈荣，彭德昌，胡祖力,等.颅内血管周细胞瘤与血管瘤型脑膜瘤的磁共振成像征象对比分析.磁共振成像杂志, 2016, 7(3): 173-179.
[11]
Oshino S, Kato A, Wakayama A, et al. Magnetoencephalographic analysis of cortical oscillatory activity in patients with brain tumors: synthetic aperture magnetometry (SAM) functional imaging of delta band activity. Neuroimage, 2007, 34(3): 957-964.
[12]
程敬亮，赵艺蕾，王斐斐,等.脑膜瘤"脑膜尾征"的MRI表现及其病理学基础.磁共振成像, 2010, 1(2): 115-119.
[13]
Bulakbasi N, Guvenc I, Onguru O, et al. The added value of the apparent diffusion coefficient calculation to magnetic resonance imaging in the differentiation and grading of malignant brain tumors. J Comput Assist Tomogr, 2004, 28(6): 735-746.
[14]
Liu G, Chen ZY, Ma L, et al. Intracranial hemangiopericytoma: MR imaging findings and diagnostic usefulness of minimum ADC values. J Magn Reson Imaging, 2013, 38(5): 1146-1151.
[15]
李桥，周碧婧，何慧瑾,等. ADC值在鉴别血管外皮细胞瘤与脑膜瘤中的应用.中国医学计算机成像杂志, 2015, 21(5): 419-425.

PREV Middle cerebral artery plaque in patients with recurrent acute ischemic stroke: studied with high-resolution magnetic resonance imaging
NEXT Comparison of 3D-ASL and 1H-MRS magnetic resonance imaging techniques for the preoperative grading of brain glioma
  


LINK


Tel & Fax: +8610-67113815    E-mail: editor@cjmri.cn