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• Clinical Article •
Imaging and ADC value in differential diagnosis of intracranial hemangiopericytoma and anaplastic meningioma: a comparative study
CHEN Fei  SHEN Xue-jiao  MA Li  LAN Yu-xia  SUN Peng-Fei 

DOI:10.12015/issn.1674-8034.2016.11.004.


[Abstract] Objective: To analyze MRI features of intracranial hemangiopericytoma (HPC) and Anaplastic Meningioma (AM). Exploring the value of DWI and ADC value in differential diagnosis of them.Materials and Methods: The imaging data of 20 cases of HPC and 31 cases of AM pathologically confirmed were collected. They all had plain and enhanced MRI scans and diffusion weighted MRI scans. The results were analyzed in all cases.Results: Differences in tumor shape (χ2=4.763, P<0.05), hemorrhage (χ2=8.400, P<0.01), signal void of vessel (χ2=26.793, P<0.001), brain tumor interface (χ2=4.432, P<0.05), dural attachment (χ2=15.093, P<0.001), dural tail (χ2=9.670, P<0.01), enhancement (χ2=8.025, P<0.01) and homogenous enhancement (χ2=5.097, P<0.05) between HPC and AM were statistically significant. Differences in T2WI signal (χ2=3.227, P>0.05), cystic necrosis (χ2=0.658, P>0.05), peritumoral edema (χ2=0.056, P>0.05) and bone destruction (χ2=2.588, P>0.05) were not statistically significant. The former had mostly lobulated, irregular shape, cystic necrosis, hemorrhage and tumor blood flow within the empty signal more common, clear brain tumor interface, significant heterogenous enhancement, narrow base connected with dural, rare dural tail, the latter was mostly round or oval, rare cystic necrosis and hemorrhage, fuzzy brain tumor interface, significant homogenous enhancement, wide base connected with dural, dural tail more common. Twenty cases of HPC showed equal or slightly higher signal on DWI, and the ADC mean was (1.21±0.14)×10-3 mm2/s. In 28 from 31 cases of AM, DWI showed higher or slightly higher signal, 3 cases showed low signal, ADC mean was (0.82±0.12) ×10-3 mm2/s, Which was significantly lower than that of HPC (t=10.39, P<0.001). When optimal cut point of ADC was 1.07×10-3 mm2/s for diagnosis of HPC and AM, the area under the ROC curve was 0.98±0.01, 95% confidence intervals was 0.95-1.00, the sensitivity, specificity and accuracy was 90%, 100% and 90%.Conclusions: The MRI features are helpful in differential diagnosis of HPC and AM, ADC values can be applied as a complementary tool in the differential diagnosis of them, which can increase the diagnostic accuracy.
[Keywords] Hemangiopericytoma；Meningioma；Magnetic resonance imaging

CHEN Fei Department of Radiotherapy, Lanzhou University Second Hospital, Lanzhou 730030, China

SHEN Xue-jiao Department of Radiotherapy, Lanzhou University Second Hospital, Lanzhou 730030, China

MA Li Department of Radiotherapy, Lanzhou University Second Hospital, Lanzhou 730030, China

LAN Yu-xia Department of Radiotherapy, Lanzhou University Second Hospital, Lanzhou 730030, China

SUN Peng-Fei* Department of Radiotherapy, Lanzhou University Second Hospital, Lanzhou 730030, China

*Correspondence to: Sun PF, E-mail: sunpengfeiby@163.com

Conflicts of interest   None.

Received  2016-07-22
Accepted  2016-10-08
DOI: 10.12015/issn.1674-8034.2016.11.004
DOI:10.12015/issn.1674-8034.2016.11.004.

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