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Progress of PWI' application in the brain damage of diabetes
WANG Shan-cheng  LI Cheng  QU Hang  DU Fang 

DOI:10.12015/issn.1674-8034.2017.02.016.


[Abstract] Diabetic brain damage is a complication of diabetes in the central nervous system. The brain perfusion abnormalities is one of the manifestations of diabetic brain damage. Magnetic resonance perfusion imaging (PWI) can reflect the information of microcirculation, is divided into three categories, which are dynamic susceptibility contrast enhancement (DSC), dynamic contrast enhancement (DCE) and arterial spin labeling (ASL). With the development of magnetic resonance perfusion imaging, we get more early, comprehensive and accurate measurement of changes in the brain’s microcirculation. Especially, the ASL is a noninvasive method of PWI, it can be a quantitative and repeated way to meansure cerebral blood flow (CBF) and can avoid the risks bring by exogenous contrast agent effectively. ASL has been a powerful tool in diabetic research. This paper focuses on the research and application of PWI in the brain damage of diabetes.
[Keywords] Diabetic brain damage；Diabetic encephalopathy；Diabetes complications；Magnetic resonance imaging；Perfusion weighted imaging；Arterial spin labeling

WANG Shan-cheng Department of Medical Imaging, the First People’s Hospital of Yangzhou, the Second Clinical Medical College of Yangzhou University, Yangzhou 225001, China

LI Cheng Department of Radiology, Zhongda Hospital affiliated to Southeast University, Nanjing 210000, China

QU Hang Department of Medical Imaging, the First People’s Hospital of Yangzhou, the Second Clinical Medical College of Yangzhou University, Yangzhou 225001, China

DU Fang* Department of Medical Imaging, the First People’s Hospital of Yangzhou, the Second Clinical Medical College of Yangzhou University, Yangzhou 225001, China

*Correspondence to: Du F, E-mail: yzdufang@126.com

Conflicts of interest   None.

Received  2016-10-10
Accepted  2016-11-26
DOI: 10.12015/issn.1674-8034.2017.02.016
DOI:10.12015/issn.1674-8034.2017.02.016.

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